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The map label for this gene is ubiA [H]

Identifier: 86748972

GI number: 86748972

Start: 2115250

End: 2116200

Strand: Direct

Name: ubiA [H]

Synonym: RPB_1849

Alternate gene names: 86748972

Gene position: 2115250-2116200 (Clockwise)

Preceding gene: 86748971

Following gene: 86748973

Centisome position: 39.67

GC content: 67.3

Gene sequence:

>951_bases
ATGACCGGCGTCCCGATCAGCGGCGCGACGGCGCCGGTTGCCGACTCGACCGGCAACTGGGTCGACCGCCACGCGCCGGA
ATGGTCGCGGCCTTATCTCCGCCTCGCCCGGTTCGATCGTCCGATCGGTTCCTGGCTGCTGCTGATGCCATGCTGGTGGT
CGGCGGCGCTGGCGGCCGGCATGGCCAAGGAGCTCGGCCAACTGCCGCTGTTCTGCGCGCTGTTCTTCGTCGGCGCCTTC
GTGATGCGCGGCGCCGGCTGCACCTGGAACGACATCACCGACCGCGATCTCGACGGCAAGGTCGAGCGCACCCGGTCGCG
GCCGATCCCGGCCGGCCAGGTCACCGCCAAGCAGGCCGCCGCCTTCATGGTGACGCTGTCCTTCATCGGCCTTGCGGTTC
TTCTGCAGTTCAACAATTTCACCATCGCGACCGGCATCGCCTCGTTGATCATCGTCGCCGCCTATCCGTTCATGAAGCGG
ATCACCTACTGGCCGCAGATCGTGCTCGGGCTCGCGTTCTCGTGGGGCGCGCTGATGGGCTTCGCCGGCACGTTCGCGCG
GCTCGATCTGGTGGCGTTCGTGCTCTATGCCGGCTCGATCGCCTGGGTGGTCGGCTACGACACGATCTACGCGCATCAGG
ACGCCGAGGACGATCTGATGATCGGCATCAAGTCCACCGCGCTGCTGTTCGGCGACCGGACCCACGCCGCGCTGCTGGTT
CTCTACGGCCTCGCGGTGACGCTGCTCGGCACCGCCTTGCTGCTGGCGGACTCCGGCTGGTTCGGCTGGATCGGGCTCGC
CGCCTTCACGGTGCATCTGGTGTCGCAGATCGTCCGGCTCGACATCCACGACAGCCCGCTGTGCCTGAAGCTGTTCAAGT
CCAATCGCGACGCCGGCCTGTTGCTGTTCATCGGCCTGGCATGCGATGCCGTCGCCCGGACGATGACCTGA

Upstream 100 bases:

>100_bases
ACGTGCTCGGCTCGTCCACAGCGGCGCCCGAGGTGAATACGTCGGCCAAGAAATACGGTGGCACCACCTTCGACACGCTG
AACGGCAACGTGCTGCAGAG

Downstream 100 bases:

>100_bases
CGGCCGGCTGGCGCAAGCCTGCGCCAGCGGTTTGATTTTGATCAATTCCGACCAGTCGGGCACCGGCCAGATCGGGCCTC
GATGCTCGCGCAGCAAGGGC

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTGVPISGATAPVADSTGNWVDRHAPEWSRPYLRLARFDRPIGSWLLLMPCWWSAALAAGMAKELGQLPLFCALFFVGAF
VMRGAGCTWNDITDRDLDGKVERTRSRPIPAGQVTAKQAAAFMVTLSFIGLAVLLQFNNFTIATGIASLIIVAAYPFMKR
ITYWPQIVLGLAFSWGALMGFAGTFARLDLVAFVLYAGSIAWVVGYDTIYAHQDAEDDLMIGIKSTALLFGDRTHAALLV
LYGLAVTLLGTALLLADSGWFGWIGLAAFTVHLVSQIVRLDIHDSPLCLKLFKSNRDAGLLLFIGLACDAVARTMT

Sequences:

>Translated_316_residues
MTGVPISGATAPVADSTGNWVDRHAPEWSRPYLRLARFDRPIGSWLLLMPCWWSAALAAGMAKELGQLPLFCALFFVGAF
VMRGAGCTWNDITDRDLDGKVERTRSRPIPAGQVTAKQAAAFMVTLSFIGLAVLLQFNNFTIATGIASLIIVAAYPFMKR
ITYWPQIVLGLAFSWGALMGFAGTFARLDLVAFVLYAGSIAWVVGYDTIYAHQDAEDDLMIGIKSTALLFGDRTHAALLV
LYGLAVTLLGTALLLADSGWFGWIGLAAFTVHLVSQIVRLDIHDSPLCLKLFKSNRDAGLLLFIGLACDAVARTMT
>Mature_315_residues
TGVPISGATAPVADSTGNWVDRHAPEWSRPYLRLARFDRPIGSWLLLMPCWWSAALAAGMAKELGQLPLFCALFFVGAFV
MRGAGCTWNDITDRDLDGKVERTRSRPIPAGQVTAKQAAAFMVTLSFIGLAVLLQFNNFTIATGIASLIIVAAYPFMKRI
TYWPQIVLGLAFSWGALMGFAGTFARLDLVAFVLYAGSIAWVVGYDTIYAHQDAEDDLMIGIKSTALLFGDRTHAALLVL
YGLAVTLLGTALLLADSGWFGWIGLAAFTVHLVSQIVRLDIHDSPLCLKLFKSNRDAGLLLFIGLACDAVARTMT

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=288, Percent_Identity=46.875, Blast_Score=235, Evalue=5e-62,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=40.3636363636364, Blast_Score=175, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17553718, Length=295, Percent_Identity=44.0677966101695, Blast_Score=220, Evalue=8e-58,
Organism=Caenorhabditis elegans, GI32565247, Length=285, Percent_Identity=43.859649122807, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17553720, Length=192, Percent_Identity=46.875, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI32565245, Length=149, Percent_Identity=49.6644295302013, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI32565243, Length=148, Percent_Identity=49.3243243243243, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324370, Length=302, Percent_Identity=40.0662251655629, Blast_Score=199, Evalue=4e-52,
Organism=Drosophila melanogaster, GI21355567, Length=303, Percent_Identity=44.8844884488449, Blast_Score=234, Evalue=5e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34269; Mature: 34137

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGVPISGATAPVADSTGNWVDRHAPEWSRPYLRLARFDRPIGSWLLLMPCWWSAALAAG
CCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MAKELGQLPLFCALFFVGAFVMRGAGCTWNDITDRDLDGKVERTRSRPIPAGQVTAKQAA
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHH
AFMVTLSFIGLAVLLQFNNFTIATGIASLIIVAAYPFMKRITYWPQIVLGLAFSWGALMG
HHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAGTFARLDLVAFVLYAGSIAWVVGYDTIYAHQDAEDDLMIGIKSTALLFGDRTHAALLV
HHHHHHHHHHHHHHHHHCCEEEEEECHHEEECCCCCCCEEEEEEHHEEEECCCHHHHHHH
LYGLAVTLLGTALLLADSGWFGWIGLAAFTVHLVSQIVRLDIHDSPLCLKLFKSNRDAGL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCE
LLFIGLACDAVARTMT
EEHHHHHHHHHHHCCC
>Mature Secondary Structure 
TGVPISGATAPVADSTGNWVDRHAPEWSRPYLRLARFDRPIGSWLLLMPCWWSAALAAG
CCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MAKELGQLPLFCALFFVGAFVMRGAGCTWNDITDRDLDGKVERTRSRPIPAGQVTAKQAA
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHH
AFMVTLSFIGLAVLLQFNNFTIATGIASLIIVAAYPFMKRITYWPQIVLGLAFSWGALMG
HHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAGTFARLDLVAFVLYAGSIAWVVGYDTIYAHQDAEDDLMIGIKSTALLFGDRTHAALLV
HHHHHHHHHHHHHHHHHCCEEEEEECHHEEECCCCCCCEEEEEEHHEEEECCCHHHHHHH
LYGLAVTLLGTALLLADSGWFGWIGLAAFTVHLVSQIVRLDIHDSPLCLKLFKSNRDAGL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCE
LLFIGLACDAVARTMT
EEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA