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The map label for this gene is yciR [C]

Identifier: 86748936

GI number: 86748936

Start: 2072969

End: 2075302

Strand: Direct

Name: yciR [C]

Synonym: RPB_1813

Alternate gene names: 86748936

Gene position: 2072969-2075302 (Clockwise)

Preceding gene: 86748935

Following gene: 86748937

Centisome position: 38.88

GC content: 64.7

Gene sequence:

>2334_bases
ATGCAGCTTGCCAGCCAAAAACACGACGCCGATCCTGAGATGTCGCCGGCTATCCACGCCGGGCTGGTCGAGTCGCTATT
CATGAATCCGGCGCCGATGATCGTCGGCGCGTTCGGGCCCGCGATCGCCGGATCGGTGATCGGGTTCGTCACCGGCAATG
TCTGGAATTGGCTCTGCGTTCCCCTGTTTGTCCTGGTCGGTATCGCGCGCGCGATGCAGATGCGCCGCTACCGCGAGCGG
AACGCGCCGCTTTCGCAGCACGATGCCGATGTCTGGGAAAAGCGCTACCGGCTTGGCGCGATCACGCACGGCATTTCGCT
CGGCATCTGGTCGTTGGTGGTCCTGCTGGATACGCAGGACACCGGCGCGCACATGCTCTGCATCACCACCGTCGTGGCCT
ACACATCGGCGGGCGTCGGCCGCACCTTCGGACGGCCCAAGATCTTTCATCTCCAGGTGCTGTTGAGCTGCGGACCTTTG
ATCATCGCGTTGATCATGGTCGGTGGCATCTACTATCTGGCGCTGGCTCTGCTCAGCACGGTGTTCTTCATCGCCATCCG
GCAGGTGACGTCGAGCTTGCAGCGGATCTATCTCGACGCCTGGATCGGTCGGGAGCGGGAGGCGGCGCTGGCACACCAGT
TCGATACGGCGCTGAACAACATGCCGCACGGCCTGTGCATGTTTCGCGCCGACGGGCGGCTGGCGGTGATGAACAATCGC
TTCGCTGAAATGATGAAGCTCGGCGGTGCGCTGGCCGAAGGCTCCCCGAGCGCGACCGAGATCGTCGCGACCTGCGTGAC
GGTGGGCGCCATTTCGGCGTCGAGCGGCCGCCTGATTCTGTCCGAGATCGACAATTCCCTGGCCGGTGAGATCGTCACCG
TCGGCGACGAGCCGGCGCCGCGCTCTTTGTCCTGGACATTCCAGCCGATGCCCGGCGGCGGCACGGTGGTGCTGGTCGAG
GACATCACCGAACGCCGCAACGCCGAAGCGCGCATCGTGCATCTGGCGCGTTACGACGAACTCACCACGTTGCCGAACCG
GGTGCAGTTCCGTGACGAAATCGAACGGATCCTCTCGCTCGAGCACGGCCACGGCAAGACGCGGCTGTCGGCACTGCTGT
TCATCGATCTCGATCAGTTCAAACAGGTCAACGACACGCTCGGCCATCCCTTGGGCGACCGGCTGCTGTGCGCGGTCGCG
GACCGGTTGCGCGACATGCTGCGGCCGGAGGACTTCGTGGCGCGGTTCGGCGGCGACGAGTTCGTCGTTTTCCAGCAGAA
CGTCCGCTCCGACGAGGACGCGGCCGTGCTGGCGCGGCGGATCGTCGAGCGGCTCAGCGACCGCTATCTGATCGAGCATC
ACGTCGTCGAGATCGGCGCCTCGATCGGCATCGCGATGACCTCGCCCGGCATTCGCGCCGACATCCTGCTGAAAAACGCC
GACATGGCGCTGTATCGCGCCAAGGCCGACGGCCGCGGCACCTTCTGCTTTTTCCGCGAGGAGATGGCGCACACCGTCGA
GGCGCGCCGCATTCTCGAACTCGATCTGCGCAAGGCGCTCGCCAACGAGGAGTTCGAGCTCTACTACCAGCCGCTGGTCA
ATCTCAAGACCGGACGGATCACGACCTGCGAGGCGCTGCTGCGCTGGAATCATCCGGTGCGCGGCACCGTGTCGCCGGTC
GACATCATCCCGGTCGCCGAAGAAATGGGCCTGATCGTCGATCTCGGTCGCTGGATCCTGCGCAAGGCGTGCATGGAATG
TATGATGTGGCCGAAGCAGGTCAGCGTTGCGGTCAACTTCTCCTCGCAGCAATTCCATCAGCGCGATATCCTCAACGAGG
TGCGCTACGCGCTCGAGGTGTCGGGCCTGCCGGCCAGCCGGCTCGAAATCGAGATCACCGAGTCCTCGCTGCTGCGCAAC
ACCCAGTTCACCCACGACGCGCTCGCGCAATTGCATGGCGAGGGCGTGCGGATCGCGCTCGATGATTTCGGCACCGGCTA
TTCGAGCCTGAGCTATCTGCACACGTTCCCGCTGCAGAAGGTCAAGATCGATCGCTCCTTCCTCGAGGGCATCGACAGCG
ACCGGCCGCTCACGCTGCTGCGTGGCGTGGCGCGGTTGAGCGCCGATCTCGGCATGTCCGTGGTGGTCGAGGGCATCGAG
ACCAACGAGCAGCTCGAGCTGATCAGTGCCGACGGCACCGTCACCGAAGCGCAGGGCTATTTGTTCAGCCGCCCGGTTCC
CGCTGCCCGCGTCCGGAAGCTGCTGACCGCCTCGCACGGCGAGCGTCAGAAGGACGGCAAGGTGCTGTCGATTCCGCTCC
GCTCCATCGCCTGA

Upstream 100 bases:

>100_bases
GGGGTTTCGCGGAGTCGCGTAACGTCTCGCTAATCATCTTCACTCAGAAAGAGTTCATCTGCTCGGGATATAACGGGGCT
GAAAGGACCGCTTGCGCCTG

Downstream 100 bases:

>100_bases
TCCGACCATCGATCGCCTGAGCCGCGCGGAGATTTCGCAGGTCTGATTAACCCTAACGTTTCAAATGCTTTGCTTCGTCA
TTAAGGGGCCGTTAACGTTC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 777; Mature: 777

Protein sequence:

>777_residues
MQLASQKHDADPEMSPAIHAGLVESLFMNPAPMIVGAFGPAIAGSVIGFVTGNVWNWLCVPLFVLVGIARAMQMRRYRER
NAPLSQHDADVWEKRYRLGAITHGISLGIWSLVVLLDTQDTGAHMLCITTVVAYTSAGVGRTFGRPKIFHLQVLLSCGPL
IIALIMVGGIYYLALALLSTVFFIAIRQVTSSLQRIYLDAWIGREREAALAHQFDTALNNMPHGLCMFRADGRLAVMNNR
FAEMMKLGGALAEGSPSATEIVATCVTVGAISASSGRLILSEIDNSLAGEIVTVGDEPAPRSLSWTFQPMPGGGTVVLVE
DITERRNAEARIVHLARYDELTTLPNRVQFRDEIERILSLEHGHGKTRLSALLFIDLDQFKQVNDTLGHPLGDRLLCAVA
DRLRDMLRPEDFVARFGGDEFVVFQQNVRSDEDAAVLARRIVERLSDRYLIEHHVVEIGASIGIAMTSPGIRADILLKNA
DMALYRAKADGRGTFCFFREEMAHTVEARRILELDLRKALANEEFELYYQPLVNLKTGRITTCEALLRWNHPVRGTVSPV
DIIPVAEEMGLIVDLGRWILRKACMECMMWPKQVSVAVNFSSQQFHQRDILNEVRYALEVSGLPASRLEIEITESSLLRN
TQFTHDALAQLHGEGVRIALDDFGTGYSSLSYLHTFPLQKVKIDRSFLEGIDSDRPLTLLRGVARLSADLGMSVVVEGIE
TNEQLELISADGTVTEAQGYLFSRPVPAARVRKLLTASHGERQKDGKVLSIPLRSIA

Sequences:

>Translated_777_residues
MQLASQKHDADPEMSPAIHAGLVESLFMNPAPMIVGAFGPAIAGSVIGFVTGNVWNWLCVPLFVLVGIARAMQMRRYRER
NAPLSQHDADVWEKRYRLGAITHGISLGIWSLVVLLDTQDTGAHMLCITTVVAYTSAGVGRTFGRPKIFHLQVLLSCGPL
IIALIMVGGIYYLALALLSTVFFIAIRQVTSSLQRIYLDAWIGREREAALAHQFDTALNNMPHGLCMFRADGRLAVMNNR
FAEMMKLGGALAEGSPSATEIVATCVTVGAISASSGRLILSEIDNSLAGEIVTVGDEPAPRSLSWTFQPMPGGGTVVLVE
DITERRNAEARIVHLARYDELTTLPNRVQFRDEIERILSLEHGHGKTRLSALLFIDLDQFKQVNDTLGHPLGDRLLCAVA
DRLRDMLRPEDFVARFGGDEFVVFQQNVRSDEDAAVLARRIVERLSDRYLIEHHVVEIGASIGIAMTSPGIRADILLKNA
DMALYRAKADGRGTFCFFREEMAHTVEARRILELDLRKALANEEFELYYQPLVNLKTGRITTCEALLRWNHPVRGTVSPV
DIIPVAEEMGLIVDLGRWILRKACMECMMWPKQVSVAVNFSSQQFHQRDILNEVRYALEVSGLPASRLEIEITESSLLRN
TQFTHDALAQLHGEGVRIALDDFGTGYSSLSYLHTFPLQKVKIDRSFLEGIDSDRPLTLLRGVARLSADLGMSVVVEGIE
TNEQLELISADGTVTEAQGYLFSRPVPAARVRKLLTASHGERQKDGKVLSIPLRSIA
>Mature_777_residues
MQLASQKHDADPEMSPAIHAGLVESLFMNPAPMIVGAFGPAIAGSVIGFVTGNVWNWLCVPLFVLVGIARAMQMRRYRER
NAPLSQHDADVWEKRYRLGAITHGISLGIWSLVVLLDTQDTGAHMLCITTVVAYTSAGVGRTFGRPKIFHLQVLLSCGPL
IIALIMVGGIYYLALALLSTVFFIAIRQVTSSLQRIYLDAWIGREREAALAHQFDTALNNMPHGLCMFRADGRLAVMNNR
FAEMMKLGGALAEGSPSATEIVATCVTVGAISASSGRLILSEIDNSLAGEIVTVGDEPAPRSLSWTFQPMPGGGTVVLVE
DITERRNAEARIVHLARYDELTTLPNRVQFRDEIERILSLEHGHGKTRLSALLFIDLDQFKQVNDTLGHPLGDRLLCAVA
DRLRDMLRPEDFVARFGGDEFVVFQQNVRSDEDAAVLARRIVERLSDRYLIEHHVVEIGASIGIAMTSPGIRADILLKNA
DMALYRAKADGRGTFCFFREEMAHTVEARRILELDLRKALANEEFELYYQPLVNLKTGRITTCEALLRWNHPVRGTVSPV
DIIPVAEEMGLIVDLGRWILRKACMECMMWPKQVSVAVNFSSQQFHQRDILNEVRYALEVSGLPASRLEIEITESSLLRN
TQFTHDALAQLHGEGVRIALDDFGTGYSSLSYLHTFPLQKVKIDRSFLEGIDSDRPLTLLRGVARLSADLGMSVVVEGIE
TNEQLELISADGTVTEAQGYLFSRPVPAARVRKLLTASHGERQKDGKVLSIPLRSIA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=434, Percent_Identity=36.1751152073733, Blast_Score=271, Evalue=9e-74,
Organism=Escherichia coli, GI87081921, Length=435, Percent_Identity=31.7241379310345, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI226510982, Length=413, Percent_Identity=27.3607748184019, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1786507, Length=289, Percent_Identity=31.4878892733564, Blast_Score=144, Evalue=3e-35,
Organism=Escherichia coli, GI87081980, Length=265, Percent_Identity=35.4716981132075, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI87081845, Length=248, Percent_Identity=34.6774193548387, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1788502, Length=240, Percent_Identity=37.5, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1790496, Length=236, Percent_Identity=29.2372881355932, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1787055, Length=261, Percent_Identity=29.8850574712644, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1788381, Length=204, Percent_Identity=36.7647058823529, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI87081743, Length=236, Percent_Identity=30.5084745762712, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI87081881, Length=178, Percent_Identity=38.2022471910112, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082096, Length=261, Percent_Identity=27.9693486590038, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1787262, Length=167, Percent_Identity=34.7305389221557, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI87081977, Length=180, Percent_Identity=33.8888888888889, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788849, Length=238, Percent_Identity=30.2521008403361, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1786584, Length=163, Percent_Identity=33.7423312883436, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788956, Length=163, Percent_Identity=34.9693251533742, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI145693134, Length=160, Percent_Identity=36.875, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787816, Length=132, Percent_Identity=34.0909090909091, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1788085, Length=164, Percent_Identity=30.4878048780488, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082007, Length=162, Percent_Identity=32.7160493827161, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081974, Length=157, Percent_Identity=33.1210191082803, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 85983; Mature: 85983

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLASQKHDADPEMSPAIHAGLVESLFMNPAPMIVGAFGPAIAGSVIGFVTGNVWNWLCV
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHH
PLFVLVGIARAMQMRRYRERNAPLSQHDADVWEKRYRLGAITHGISLGIWSLVVLLDTQD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCC
TGAHMLCITTVVAYTSAGVGRTFGRPKIFHLQVLLSCGPLIIALIMVGGIYYLALALLST
CCCHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VFFIAIRQVTSSLQRIYLDAWIGREREAALAHQFDTALNNMPHGLCMFRADGRLAVMNNR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEHHH
FAEMMKLGGALAEGSPSATEIVATCVTVGAISASSGRLILSEIDNSLAGEIVTVGDEPAP
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCEECCCCCEEHHHHCCHHCCCEEEECCCCCC
RSLSWTFQPMPGGGTVVLVEDITERRNAEARIVHLARYDELTTLPNRVQFRDEIERILSL
CCCEEEEEECCCCCEEEEEECHHHCCCCCEEEEEEEHHHHHHCCCCHHHHHHHHHHHHHC
EHGHGKTRLSALLFIDLDQFKQVNDTLGHPLGDRLLCAVADRLRDMLRPEDFVARFGGDE
CCCCCHHEEEEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCE
FVVFQQNVRSDEDAAVLARRIVERLSDRYLIEHHVVEIGASIGIAMTSPGIRADILLKNA
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECC
DMALYRAKADGRGTFCFFREEMAHTVEARRILELDLRKALANEEFELYYQPLVNLKTGRI
CEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCC
TTCEALLRWNHPVRGTVSPVDIIPVAEEMGLIVDLGRWILRKACMECMMWPKQVSVAVNF
HHHHHHHHCCCCCCCCCCCCEEEECHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
SSQQFHQRDILNEVRYALEVSGLPASRLEIEITESSLLRNTQFTHDALAQLHGEGVRIAL
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHCCCCHHHHHHHHCCCCEEEEE
DDFGTGYSSLSYLHTFPLQKVKIDRSFLEGIDSDRPLTLLRGVARLSADLGMSVVVEGIE
ECCCCCHHHHHHHHHCCCHHHEECHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCC
TNEQLELISADGTVTEAQGYLFSRPVPAARVRKLLTASHGERQKDGKVLSIPLRSIA
CCCEEEEEECCCCEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEECHHHCC
>Mature Secondary Structure
MQLASQKHDADPEMSPAIHAGLVESLFMNPAPMIVGAFGPAIAGSVIGFVTGNVWNWLCV
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHH
PLFVLVGIARAMQMRRYRERNAPLSQHDADVWEKRYRLGAITHGISLGIWSLVVLLDTQD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCC
TGAHMLCITTVVAYTSAGVGRTFGRPKIFHLQVLLSCGPLIIALIMVGGIYYLALALLST
CCCHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VFFIAIRQVTSSLQRIYLDAWIGREREAALAHQFDTALNNMPHGLCMFRADGRLAVMNNR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEHHH
FAEMMKLGGALAEGSPSATEIVATCVTVGAISASSGRLILSEIDNSLAGEIVTVGDEPAP
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCEECCCCCEEHHHHCCHHCCCEEEECCCCCC
RSLSWTFQPMPGGGTVVLVEDITERRNAEARIVHLARYDELTTLPNRVQFRDEIERILSL
CCCEEEEEECCCCCEEEEEECHHHCCCCCEEEEEEEHHHHHHCCCCHHHHHHHHHHHHHC
EHGHGKTRLSALLFIDLDQFKQVNDTLGHPLGDRLLCAVADRLRDMLRPEDFVARFGGDE
CCCCCHHEEEEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCE
FVVFQQNVRSDEDAAVLARRIVERLSDRYLIEHHVVEIGASIGIAMTSPGIRADILLKNA
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECC
DMALYRAKADGRGTFCFFREEMAHTVEARRILELDLRKALANEEFELYYQPLVNLKTGRI
CEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCC
TTCEALLRWNHPVRGTVSPVDIIPVAEEMGLIVDLGRWILRKACMECMMWPKQVSVAVNF
HHHHHHHHCCCCCCCCCCCCEEEECHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
SSQQFHQRDILNEVRYALEVSGLPASRLEIEITESSLLRNTQFTHDALAQLHGEGVRIAL
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHCCCCHHHHHHHHCCCCEEEEE
DDFGTGYSSLSYLHTFPLQKVKIDRSFLEGIDSDRPLTLLRGVARLSADLGMSVVVEGIE
ECCCCCHHHHHHHHHCCCHHHEECHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCC
TNEQLELISADGTVTEAQGYLFSRPVPAARVRKLLTASHGERQKDGKVLSIPLRSIA
CCCEEEEEECCCCEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEECHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]