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The map label for this gene is aprE [H]

Identifier: 86748763

GI number: 86748763

Start: 1869479

End: 1870816

Strand: Direct

Name: aprE [H]

Synonym: RPB_1640

Alternate gene names: 86748763

Gene position: 1869479-1870816 (Clockwise)

Preceding gene: 86748762

Following gene: 86748764

Centisome position: 35.06

GC content: 59.94

Gene sequence:

>1338_bases
ATGCAATCCGCTCAATCGGAAGATCTCGCCGTCCAATTGAAGTCTCAGTTGCGGCCTGTGGTGTGGGGCGCGACCGTCGT
GATCGGGGTGTTTCTGTTCGCGATGACCGCCTGGAGCGTCGGCGCGCCGATGTCGAGCGCCGCGATCGCGTCGGGGGTCG
TGAGCCCCGATGGTAGCCGCAAGACGCTCCAGCATCTCGAAGGCGGCATTGTCCGCGAATTGCTGGTGCGCGAGGGCGAT
CACGTTCAGGCCGGGCAAGTCCTGATGCGTCTGGACCTGACGCAGGCGAGGGCGAATTTCACCGCAAAGCGCGACGAATG
GCTCCGGCTGCAGGCGATCAGGGCCCGCTACGAATCGCACGGGCTCAATCTCGAAGAGATGCGAATCCCGCAGGTGCTTC
TCGACGACAAGAGCGAAGAATTCACGGCCTTCATCGAGAACGAAAAGAAGCTGTTCGAAGGCCGCCGGCTGGAAGTGATC
GCGCGAGAGGACATCTACAATCAGCAGATCAAGCAGATCGAAGCCGAAATCAACGGGAAGCATCTCGAGCGGGAAGGCCT
CGACAAGATGCGAGGCTTCATCAATGAGGAGATCGGCGACAAGAGCGGGCTGCTGTTGCAGAACCTGGTGCGCAAGCCAG
AGGTCTTGGCGCTGCAACGCACCGAGGCGGAACTGACCTCCAAGATCGGGGTCAATCTGTCCGACATCGGGCGTGCGGAG
CAGAAGATCAAAGAGGTGCTGCTCGCCATGCGCGCCGTTCAAACCAAGTTCCGCGACGAGAATTCGGAACAGTTGATGAA
GGTGACCCGCGACATTGCCCAGATAGAAGGATCGCTGACGAATACCGGCGACATTCTCAGCCGGACCGACCTGATAGCGC
CGGTGTCCGGAACGGTCTTGCAGTTGCGCTTCAAGACCGTAGGCGGTGTCGTCAAGGCCGGCGACCAGATTCTCGACATC
GTGCCCGATGACGATGTGCTGGTGATCGATGCGAAACTCTCACCCACGGACATCGATGTGGTGCGGGTGGGCATGCCGGC
TCAGGTTCACTTTGATGCCTATGTCTCGCGTCGGACGCCGATGTTCGAAGGTGTCGTCAATCACGTGAGCTCGGACGCCA
TCGTCGATCAGGCGGCAGCGAACGCGCTGCAGCAGCGCTACTACCAGGTAAAGGTGCAAATCGACCGGAAGCAGATCGAT
CAGTACAAGCACATCACGCTGGTGCCCGGCATGCCCGCGGAAGCGTTCATCATGACCGGAACGCGGACTTTGTTCGAATA
CCTGACTGCGCCGATCCTCACGTCGTTCCGAAGGGCATTCCGCGAGGACTACAATTGA

Upstream 100 bases:

>100_bases
TCTCCAGCCGCGCCGCGCGCAGCGGAAACGATCAAACCATGCCGGTGCCGGCCCGCGCGTCGGGTGCCGCGCCGGCTCAC
CAGTGACGGGAACGACTGCC

Downstream 100 bases:

>100_bases
GTTCCTCATGAGTTGGTTCGACTGGCCGTGACGATGCCCCCAGCGCCATAGCGCGACGGTGCGCATTGCCTCGTTCCGAT
GGCCTGCCCGCCGTCCCGGC

Product: Type I secretion membrane fusion protein, HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MQSAQSEDLAVQLKSQLRPVVWGATVVIGVFLFAMTAWSVGAPMSSAAIASGVVSPDGSRKTLQHLEGGIVRELLVREGD
HVQAGQVLMRLDLTQARANFTAKRDEWLRLQAIRARYESHGLNLEEMRIPQVLLDDKSEEFTAFIENEKKLFEGRRLEVI
AREDIYNQQIKQIEAEINGKHLEREGLDKMRGFINEEIGDKSGLLLQNLVRKPEVLALQRTEAELTSKIGVNLSDIGRAE
QKIKEVLLAMRAVQTKFRDENSEQLMKVTRDIAQIEGSLTNTGDILSRTDLIAPVSGTVLQLRFKTVGGVVKAGDQILDI
VPDDDVLVIDAKLSPTDIDVVRVGMPAQVHFDAYVSRRTPMFEGVVNHVSSDAIVDQAAANALQQRYYQVKVQIDRKQID
QYKHITLVPGMPAEAFIMTGTRTLFEYLTAPILTSFRRAFREDYN

Sequences:

>Translated_445_residues
MQSAQSEDLAVQLKSQLRPVVWGATVVIGVFLFAMTAWSVGAPMSSAAIASGVVSPDGSRKTLQHLEGGIVRELLVREGD
HVQAGQVLMRLDLTQARANFTAKRDEWLRLQAIRARYESHGLNLEEMRIPQVLLDDKSEEFTAFIENEKKLFEGRRLEVI
AREDIYNQQIKQIEAEINGKHLEREGLDKMRGFINEEIGDKSGLLLQNLVRKPEVLALQRTEAELTSKIGVNLSDIGRAE
QKIKEVLLAMRAVQTKFRDENSEQLMKVTRDIAQIEGSLTNTGDILSRTDLIAPVSGTVLQLRFKTVGGVVKAGDQILDI
VPDDDVLVIDAKLSPTDIDVVRVGMPAQVHFDAYVSRRTPMFEGVVNHVSSDAIVDQAAANALQQRYYQVKVQIDRKQID
QYKHITLVPGMPAEAFIMTGTRTLFEYLTAPILTSFRRAFREDYN
>Mature_445_residues
MQSAQSEDLAVQLKSQLRPVVWGATVVIGVFLFAMTAWSVGAPMSSAAIASGVVSPDGSRKTLQHLEGGIVRELLVREGD
HVQAGQVLMRLDLTQARANFTAKRDEWLRLQAIRARYESHGLNLEEMRIPQVLLDDKSEEFTAFIENEKKLFEGRRLEVI
AREDIYNQQIKQIEAEINGKHLEREGLDKMRGFINEEIGDKSGLLLQNLVRKPEVLALQRTEAELTSKIGVNLSDIGRAE
QKIKEVLLAMRAVQTKFRDENSEQLMKVTRDIAQIEGSLTNTGDILSRTDLIAPVSGTVLQLRFKTVGGVVKAGDQILDI
VPDDDVLVIDAKLSPTDIDVVRVGMPAQVHFDAYVSRRTPMFEGVVNHVSSDAIVDQAAANALQQRYYQVKVQIDRKQID
QYKHITLVPGMPAEAFIMTGTRTLFEYLTAPILTSFRRAFREDYN

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 49837; Mature: 49837

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSAQSEDLAVQLKSQLRPVVWGATVVIGVFLFAMTAWSVGAPMSSAAIASGVVSPDGSR
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCH
KTLQHLEGGIVRELLVREGDHVQAGQVLMRLDLTQARANFTAKRDEWLRLQAIRARYESH
HHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
GLNLEEMRIPQVLLDDKSEEFTAFIENEKKLFEGRRLEVIAREDIYNQQIKQIEAEINGK
CCCHHHHCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCC
HLEREGLDKMRGFINEEIGDKSGLLLQNLVRKPEVLALQRTEAELTSKIGVNLSDIGRAE
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHEEEHHHHHHHHHHHCCCHHHHHHHH
QKIKEVLLAMRAVQTKFRDENSEQLMKVTRDIAQIEGSLTNTGDILSRTDLIAPVSGTVL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCEE
QLRFKTVGGVVKAGDQILDIVPDDDVLVIDAKLSPTDIDVVRVGMPAQVHFDAYVSRRTP
EEEHHHHCCHHHCCCCEEEECCCCCEEEEECCCCCCCCEEEEECCCCEEEHHHHHHCCCH
MFEGVVNHVSSDAIVDQAAANALQQRYYQVKVQIDRKQIDQYKHITLVPGMPAEAFIMTG
HHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEEECHHHHCCCCCEEEECCCCCCCEEECC
TRTLFEYLTAPILTSFRRAFREDYN
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQSAQSEDLAVQLKSQLRPVVWGATVVIGVFLFAMTAWSVGAPMSSAAIASGVVSPDGSR
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCH
KTLQHLEGGIVRELLVREGDHVQAGQVLMRLDLTQARANFTAKRDEWLRLQAIRARYESH
HHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
GLNLEEMRIPQVLLDDKSEEFTAFIENEKKLFEGRRLEVIAREDIYNQQIKQIEAEINGK
CCCHHHHCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCC
HLEREGLDKMRGFINEEIGDKSGLLLQNLVRKPEVLALQRTEAELTSKIGVNLSDIGRAE
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHEEEHHHHHHHHHHHCCCHHHHHHHH
QKIKEVLLAMRAVQTKFRDENSEQLMKVTRDIAQIEGSLTNTGDILSRTDLIAPVSGTVL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCEE
QLRFKTVGGVVKAGDQILDIVPDDDVLVIDAKLSPTDIDVVRVGMPAQVHFDAYVSRRTP
EEEHHHHCCHHHCCCCEEEECCCCCEEEEECCCCCCCCEEEEECCCCEEEHHHHHHCCCH
MFEGVVNHVSSDAIVDQAAANALQQRYYQVKVQIDRKQIDQYKHITLVPGMPAEAFIMTG
HHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEEECHHHHCCCCCEEEECCCCCCCEEECC
TRTLFEYLTAPILTSFRRAFREDYN
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]