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The map label for this gene is atoC [H]

Identifier: 86748554

GI number: 86748554

Start: 1618040

End: 1619542

Strand: Reverse

Name: atoC [H]

Synonym: RPB_1429

Alternate gene names: 86748554

Gene position: 1619542-1618040 (Counterclockwise)

Preceding gene: 86748555

Following gene: 86748553

Centisome position: 30.38

GC content: 67.93

Gene sequence:

>1503_bases
ATGGTTGAGCGAATTCTGATCGCGGACGACGATCCGGTGCAGCGCCGGCTGGTCGAGAACATGGTGCAGAAGTGCGGCTA
CGAGGCCGTGCTGGCCGACAGCGGCGACGCTGCGATGGCGCTGCTGACGGCGCCGGACACGGCTGCATTCGACGCCGTGG
TGCTCGATCTCGTGATGCCCGGCCTCGACGGCCTCGGCGTGCTCGGCAAGATCCGCGAGGCCGGCCTGAACGTGCCGGTG
ATCGTGCAGACCGCGCATGGCGGCATCGACAATGTGGTCTCGGCGATGCGCGCCGGCGCGCACGACTTCGTCGTCAAGCC
GGTCGGTATCGAGCGGCTGCAGGTCAGCTTGCGCAACGCACTCAACGCCAGCGCCCTGAAGGGCGAGTTGCAGCGAATCC
GTCACAGCCGCGAAGGCCGGCTGACGTTTTCCGACATCATCACCCGCAGCGACGCGATGGCCGCCGTGCTGCGCGCCGCG
CAGAAGGCCGCGGGCTCGTCGATCCCGGTGCTGATCGAGGGCGAATCCGGTGTCGGCAAGGAGATGTTCGCGCGCGCCAT
CCACGGCTCGAGCGAGCGACAGAGCAAGCCGTTCGTCGCCGTGAATTGCGGCGCGATCCCGGACAATCTGGTCGAGTCGA
TCCTGTTCGGGCACGAGAAGGGCGCGTTCACCGGCGCCACCGATCGCCACATGGGCAAGTTCGTCGAAGCCAGCGGCGGC
ACGCTGTTTCTCGACGAGGTCAGCGAATTACCGTTGGCCGCCCAGGTCAAGCTGCTGCGCGCGCTGCAGGAAGGCGCCGT
CGAGGCGGTCGGCGGACGCAAGCCGTTGAAGGTCGACGTCCGTATCATCTCGGCGACCAATCGCCGGCTGCTCGACCGGG
TCAAGGCCGGCCAGTTCCGCGAGGATCTGTTCTACCGCCTGCACGTCCTGCCGCTGACGGTGCCGCCGCTGCGGACGCGG
CGCGAGGACATCCCGCCGCTGCTGCGGCATTTTCTGGTGCGGTTCTGCGCCGAGGAGAACCGCAAGATCGGCGGCATCAG
CGGCGAAGCGATGGCCCGCCTTGCCCAGCTCGACTGGCCCGGCAACATCCGCCAGCTCGAAAACGCGGTGTATCGCGCCG
TGGTGATGAGCGAGGGCGATCAGCTCGGCATCGACGACTTCCCGCTGGCGAGCGCGCCCTCGACGGTGCCGACCGGCGAG
GCCGACGGCGAGCCGCTAATCCTGGAGCCGCCGGGGTCGGCGCAATTCGTCGTGGCCAACGAGGCGCCGATCGCACCGCT
GAGCACCCACGGCAGCCTGCAGATGCTGAACGCCAGCGGCGACGTCCGCGCACTGGACGAGTTGGAGAACGAGATCATCC
GCTTTGCGATCTCGCATTATCGCGGCCAGATGTCGGAAGTGGCGAGGCGGCTGAAAATCGGCCGCTCGACCCTGTATCGC
AAGCTCGACGAAATGGAAGCGGCGCGCGCAGCCAAGGCGTCGACGCCGGCGGACACACGCTGA

Upstream 100 bases:

>100_bases
CTGGCCGCACGCATTCGCAATGCTCTGACGTCTTCACGGGTCGTTAACGCTTTCACGCCCATGGTGCACCAATTCGGGAC
ACTGCGGGCTTGAGAGTGGT

Downstream 100 bases:

>100_bases
GCGAATTGTGGCGGCGCCGCGGCAAAGGCGGCGCCCAAATACCCGCCGGGAACATTCGAACCGTTGCGGTGTGGTGACAG
ACAAAGCTGGCAACACATGG

Product: two component, sigma54 specific, Fis family transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MVERILIADDDPVQRRLVENMVQKCGYEAVLADSGDAAMALLTAPDTAAFDAVVLDLVMPGLDGLGVLGKIREAGLNVPV
IVQTAHGGIDNVVSAMRAGAHDFVVKPVGIERLQVSLRNALNASALKGELQRIRHSREGRLTFSDIITRSDAMAAVLRAA
QKAAGSSIPVLIEGESGVGKEMFARAIHGSSERQSKPFVAVNCGAIPDNLVESILFGHEKGAFTGATDRHMGKFVEASGG
TLFLDEVSELPLAAQVKLLRALQEGAVEAVGGRKPLKVDVRIISATNRRLLDRVKAGQFREDLFYRLHVLPLTVPPLRTR
REDIPPLLRHFLVRFCAEENRKIGGISGEAMARLAQLDWPGNIRQLENAVYRAVVMSEGDQLGIDDFPLASAPSTVPTGE
ADGEPLILEPPGSAQFVVANEAPIAPLSTHGSLQMLNASGDVRALDELENEIIRFAISHYRGQMSEVARRLKIGRSTLYR
KLDEMEAARAAKASTPADTR

Sequences:

>Translated_500_residues
MVERILIADDDPVQRRLVENMVQKCGYEAVLADSGDAAMALLTAPDTAAFDAVVLDLVMPGLDGLGVLGKIREAGLNVPV
IVQTAHGGIDNVVSAMRAGAHDFVVKPVGIERLQVSLRNALNASALKGELQRIRHSREGRLTFSDIITRSDAMAAVLRAA
QKAAGSSIPVLIEGESGVGKEMFARAIHGSSERQSKPFVAVNCGAIPDNLVESILFGHEKGAFTGATDRHMGKFVEASGG
TLFLDEVSELPLAAQVKLLRALQEGAVEAVGGRKPLKVDVRIISATNRRLLDRVKAGQFREDLFYRLHVLPLTVPPLRTR
REDIPPLLRHFLVRFCAEENRKIGGISGEAMARLAQLDWPGNIRQLENAVYRAVVMSEGDQLGIDDFPLASAPSTVPTGE
ADGEPLILEPPGSAQFVVANEAPIAPLSTHGSLQMLNASGDVRALDELENEIIRFAISHYRGQMSEVARRLKIGRSTLYR
KLDEMEAARAAKASTPADTR
>Mature_500_residues
MVERILIADDDPVQRRLVENMVQKCGYEAVLADSGDAAMALLTAPDTAAFDAVVLDLVMPGLDGLGVLGKIREAGLNVPV
IVQTAHGGIDNVVSAMRAGAHDFVVKPVGIERLQVSLRNALNASALKGELQRIRHSREGRLTFSDIITRSDAMAAVLRAA
QKAAGSSIPVLIEGESGVGKEMFARAIHGSSERQSKPFVAVNCGAIPDNLVESILFGHEKGAFTGATDRHMGKFVEASGG
TLFLDEVSELPLAAQVKLLRALQEGAVEAVGGRKPLKVDVRIISATNRRLLDRVKAGQFREDLFYRLHVLPLTVPPLRTR
REDIPPLLRHFLVRFCAEENRKIGGISGEAMARLAQLDWPGNIRQLENAVYRAVVMSEGDQLGIDDFPLASAPSTVPTGE
ADGEPLILEPPGSAQFVVANEAPIAPLSTHGSLQMLNASGDVRALDELENEIIRFAISHYRGQMSEVARRLKIGRSTLYR
KLDEMEAARAAKASTPADTR

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=480, Percent_Identity=41.0416666666667, Blast_Score=337, Evalue=2e-93,
Organism=Escherichia coli, GI1788550, Length=483, Percent_Identity=40.1656314699793, Blast_Score=336, Evalue=2e-93,
Organism=Escherichia coli, GI1790299, Length=483, Percent_Identity=40.3726708074534, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI1788905, Length=374, Percent_Identity=43.048128342246, Blast_Score=285, Evalue=4e-78,
Organism=Escherichia coli, GI87082117, Length=260, Percent_Identity=50.3846153846154, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1789087, Length=257, Percent_Identity=47.4708171206226, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1789233, Length=339, Percent_Identity=40.4129793510324, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI87082152, Length=268, Percent_Identity=44.0298507462687, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1787583, Length=259, Percent_Identity=42.8571428571429, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI87081872, Length=246, Percent_Identity=42.6829268292683, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1786524, Length=252, Percent_Identity=44.8412698412698, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI87081858, Length=331, Percent_Identity=30.8157099697885, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789828, Length=270, Percent_Identity=34.8148148148148, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790552, Length=130, Percent_Identity=30, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789402, Length=108, Percent_Identity=34.2592592592593, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53909; Mature: 53909

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVERILIADDDPVQRRLVENMVQKCGYEAVLADSGDAAMALLTAPDTAAFDAVVLDLVMP
CCCEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHC
GLDGLGVLGKIREAGLNVPVIVQTAHGGIDNVVSAMRAGAHDFVVKPVGIERLQVSLRNA
CCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
LNASALKGELQRIRHSREGRLTFSDIITRSDAMAAVLRAAQKAAGSSIPVLIEGESGVGK
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCH
EMFARAIHGSSERQSKPFVAVNCGAIPDNLVESILFGHEKGAFTGATDRHMGKFVEASGG
HHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHEECCCC
TLFLDEVSELPLAAQVKLLRALQEGAVEAVGGRKPLKVDVRIISATNRRLLDRVKAGQFR
EEEECCHHCCCHHHHHHHHHHHHHCCHHHCCCCCCEEEEEEEEEHHHHHHHHHHHCCHHH
EDLFYRLHVLPLTVPPLRTRREDIPPLLRHFLVRFCAEENRKIGGISGEAMARLAQLDWP
HHHHHEEEEEEECCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
GNIRQLENAVYRAVVMSEGDQLGIDDFPLASAPSTVPTGEADGEPLILEPPGSAQFVVAN
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEC
EAPIAPLSTHGSLQMLNASGDVRALDELENEIIRFAISHYRGQMSEVARRLKIGRSTLYR
CCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLDEMEAARAAKASTPADTR
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVERILIADDDPVQRRLVENMVQKCGYEAVLADSGDAAMALLTAPDTAAFDAVVLDLVMP
CCCEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHC
GLDGLGVLGKIREAGLNVPVIVQTAHGGIDNVVSAMRAGAHDFVVKPVGIERLQVSLRNA
CCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
LNASALKGELQRIRHSREGRLTFSDIITRSDAMAAVLRAAQKAAGSSIPVLIEGESGVGK
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCH
EMFARAIHGSSERQSKPFVAVNCGAIPDNLVESILFGHEKGAFTGATDRHMGKFVEASGG
HHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHEECCCC
TLFLDEVSELPLAAQVKLLRALQEGAVEAVGGRKPLKVDVRIISATNRRLLDRVKAGQFR
EEEECCHHCCCHHHHHHHHHHHHHCCHHHCCCCCCEEEEEEEEEHHHHHHHHHHHCCHHH
EDLFYRLHVLPLTVPPLRTRREDIPPLLRHFLVRFCAEENRKIGGISGEAMARLAQLDWP
HHHHHEEEEEEECCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
GNIRQLENAVYRAVVMSEGDQLGIDDFPLASAPSTVPTGEADGEPLILEPPGSAQFVVAN
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEC
EAPIAPLSTHGSLQMLNASGDVRALDELENEIIRFAISHYRGQMSEVARRLKIGRSTLYR
CCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLDEMEAARAAKASTPADTR
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]