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The map label for this gene is nuoG [H]

Identifier: 86748477

GI number: 86748477

Start: 1540375

End: 1542993

Strand: Direct

Name: nuoG [H]

Synonym: RPB_1352

Alternate gene names: 86748477

Gene position: 1540375-1542993 (Clockwise)

Preceding gene: 86748476

Following gene: 86748478

Centisome position: 28.89

GC content: 70.41

Gene sequence:

>2619_bases
ATGACCAAGAAGATCGAGATCGACGGCCGCATCATCGAGGCCAAGGACGACGAGGACCTGTTGTCGGCATGCCTGACGCA
CGGGGTCGATGTGCCGTATTTCTGCTGGCATGGCGCGCTCGGCTCGGTCGGGGCCTGCCGGCAATGCGCCGTGAAGGTGT
ATGCCGGCCCGAACGATACCGAAGGCCGGATCGTGATGAGTTGCATGACGCCGGTCGCGGATGTCGAGCGCGTCTCGGTC
AGCGATCCCGAGGCGGTGGCGTTTCGCGCGCAGGTGATCGAGTGGCTGATGGTCAACCATCCGCACGATTGCCCGGTGTG
CGAGGAGGCCGGCTCCTGCCATCTGCAGGACATGACAATCGCCACCGGCCACGCCATTCGCCGCTATCGCTTCGACAAGC
GCACCCATCGCAATCAGGATCTCGGGCCGCTGCTGACGCACGAGATGAACCGCTGCATCGCCTGCTATCGCTGCACCCGG
TTCTATCGCGACTATGCCGGCGGGCGCGATCTCGATGCCTTCGGCGCGCACGACGACGTGTATTTCGGCCGCGCCGAGGA
CGGCCCGCTGGACAGCCCGTTCGCCGGCAATCTCGCCGAAGTGTGTCCGACCGGCGTGTTCAACGACAAGGGCTGGTCTC
AGGACTACGCGCGCAAATGGGACATGCGGGCGACGCCGTCGATCTGCCCGCATTGCTCGCTCGGCTGCAACATTCTGGTC
GATCAGCGCGACGGCCGGGTCAAGCGGGTGCAGAACCGCTATCACGGCGCGCTGAACGGCTATTTCATCTGCGATCGTGG
CCGCTACGGCCCGCTCCACGTCGTCTCCGACAAGCGTCTCCTGACGCCCTTGATGCAAGGCGAGGCCGCCAGTGAAGCCG
ACGCCTGCGCGGCGGCGCACGCCGTCGTTGCCGAAGGCGCGATCGGCATCGGCTCGCCGCGCGCCTCGCTGGAGGCGAAC
TACGCGTTGCAGCGGCTGGTCGGGCCGGAGCGGTTCTTCGCCGGCGTCTCCGACGCCGAGGCGACGATGGTCCGCCGCAT
CGTCGCGATTGTGCGCGCGGGACCCGCGACCGTGGCGTCGCTTGCGGATGTGGAGCGGGCCGACGCCGTGCTGGTGCTGG
GCGACGATCTCACCAACGCATCGCCGCGGCTGGCGCTGGCGCTGCGGCAGACCGCGCGCGGCGCCGAGCGCGACCTCGCG
GAACAGAAGGGCGTGCCGCGCTGGCTCGATCCGGCGGTGCGAACCGCCGGCGAAGGCCGCCGCTCGCCGATCGCGCTGGT
GACGCCGGTCGCCGATCCGCTCGATCACATCGCGGCGCTTTCTCTCCGGCGCGACCCGCAGGCGATCGCTGCGTTAGGCG
CCGGCGTCGCAGCCGCGCTGCGTGGCGAGGCGCAGGGCGATGCCGATACCACGCGCGTCGCCGAGATCCTCGCAGTCGCG
CAGCGTCCGCTGATCGTCGCCGGTTGCTCGCTCGGCGTCGCCGACATCATCGAGGCCGCAGCGGCGATCGCCTCGGCGCT
CGGCGCCAAGGCCCGGATCGTGCTGCTGCCGCCGGAGGCCAACAGCATCGGCCTGGCCTTGCTCGGCGGCGACGGTCTCG
ACAGCGCCGCGGCATTGCTGGAGCGCGGCGCGGCCAAGACAGCGATCGTGCTGGAGAACGAGCTGTTCGAACGCGCGCCG
CGCGCCAGCGTCGAACGGCTGTTCGCTGCGGCGAAGTCGGTGGTGGCGCTGGATTCGATGGCCAGCGAAACCACCGCGCG
GGCATCGGTCGCGCTGCCGGTCGCGCCGTTCACCGGCTGCGCCGGCACTTTCGTCAACTACGAGGGCCGCGCGCAGCGCT
TCTTCGCCGCGGTGCCGCCTCAGGACAGCGCGCCGTCGGCGTGGCGCAGACTCGATGCGTTCGGCGCCGGCGATTGGCAC
AGCCTCGACGCGCTGATCGGCGATCTGATCGTCGAGTGGCCGGATCTGGTCGGCGTCGCCGATGCCGCGCCGAATGCGGA
TTTCATGATGGCCGACGGCCAGGTCACGCGCGCGCCGCGGCCGTATTCCGCCCGCACCGCCGACGACCGTGCCGGACAAT
TCGCCGACGCTGTGATTCCGATCGATCCCGACGGGCCGATGACGTTCGGCATCAAGGGCGCACGCGGCACCGCGGTGCCG
CCGCCGCTGATCACCAGCTATAAGACCGCCGGCCTGCACTCTGCCAACAACGTCACGCGCTTCATGGAAGAGATCGGCGG
CCCGCTGCGCGGCGGCGATCCGGGCGCCATGCTGCTGAAGCCGAATGCGGCTGCGCTGATCGATCCGCCGCCCTCTGAAC
CCGTCGCAGGCGAAGGCCTGTTGATGGTGCCGCTGCACGATGCGTTCTCGGGTTTCGAACTCAGCCGCGCCAGTGCGCTG
CTCGCCGCCCGCGCGCCGGCGCCGCGGCTGCTGCTGCATCCCGACGACGCCGCGCTGCATGGCCTCGCGCCAGGCGCCGC
GGTGCTGATCGACGGCCGAGCCTGCGCTGCGACGATTTCGCTCGACGCCTCGCTGCCGCGCGGCTGTGTGGCGATCAGCG
CCGGCATCGACGCGCCGCGCGGGCCGCTGCGCCGGGTGCGGCTGGAGGCTGCGCGATGA

Upstream 100 bases:

>100_bases
ACCTCAACACCGGCGCGCTGACGCCGCTGCGCAGCGGCCTCGAACGCTTCGGCGATATCTTCGCTGCCCATCTGCAGGGC
TCCTGTCCGGTGGGCCGCGC

Downstream 100 bases:

>100_bases
TCGGCCTCATCATCACCGCGATCATTTCGGCCGTGCTGATCATGGCGCTGCTGGTGGTCGCCGGCACGTTTACATGGGTT
GAGCGGCGGCTGCTCGGCTT

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 872; Mature: 871

Protein sequence:

>872_residues
MTKKIEIDGRIIEAKDDEDLLSACLTHGVDVPYFCWHGALGSVGACRQCAVKVYAGPNDTEGRIVMSCMTPVADVERVSV
SDPEAVAFRAQVIEWLMVNHPHDCPVCEEAGSCHLQDMTIATGHAIRRYRFDKRTHRNQDLGPLLTHEMNRCIACYRCTR
FYRDYAGGRDLDAFGAHDDVYFGRAEDGPLDSPFAGNLAEVCPTGVFNDKGWSQDYARKWDMRATPSICPHCSLGCNILV
DQRDGRVKRVQNRYHGALNGYFICDRGRYGPLHVVSDKRLLTPLMQGEAASEADACAAAHAVVAEGAIGIGSPRASLEAN
YALQRLVGPERFFAGVSDAEATMVRRIVAIVRAGPATVASLADVERADAVLVLGDDLTNASPRLALALRQTARGAERDLA
EQKGVPRWLDPAVRTAGEGRRSPIALVTPVADPLDHIAALSLRRDPQAIAALGAGVAAALRGEAQGDADTTRVAEILAVA
QRPLIVAGCSLGVADIIEAAAAIASALGAKARIVLLPPEANSIGLALLGGDGLDSAAALLERGAAKTAIVLENELFERAP
RASVERLFAAAKSVVALDSMASETTARASVALPVAPFTGCAGTFVNYEGRAQRFFAAVPPQDSAPSAWRRLDAFGAGDWH
SLDALIGDLIVEWPDLVGVADAAPNADFMMADGQVTRAPRPYSARTADDRAGQFADAVIPIDPDGPMTFGIKGARGTAVP
PPLITSYKTAGLHSANNVTRFMEEIGGPLRGGDPGAMLLKPNAAALIDPPPSEPVAGEGLLMVPLHDAFSGFELSRASAL
LAARAPAPRLLLHPDDAALHGLAPGAAVLIDGRACAATISLDASLPRGCVAISAGIDAPRGPLRRVRLEAAR

Sequences:

>Translated_872_residues
MTKKIEIDGRIIEAKDDEDLLSACLTHGVDVPYFCWHGALGSVGACRQCAVKVYAGPNDTEGRIVMSCMTPVADVERVSV
SDPEAVAFRAQVIEWLMVNHPHDCPVCEEAGSCHLQDMTIATGHAIRRYRFDKRTHRNQDLGPLLTHEMNRCIACYRCTR
FYRDYAGGRDLDAFGAHDDVYFGRAEDGPLDSPFAGNLAEVCPTGVFNDKGWSQDYARKWDMRATPSICPHCSLGCNILV
DQRDGRVKRVQNRYHGALNGYFICDRGRYGPLHVVSDKRLLTPLMQGEAASEADACAAAHAVVAEGAIGIGSPRASLEAN
YALQRLVGPERFFAGVSDAEATMVRRIVAIVRAGPATVASLADVERADAVLVLGDDLTNASPRLALALRQTARGAERDLA
EQKGVPRWLDPAVRTAGEGRRSPIALVTPVADPLDHIAALSLRRDPQAIAALGAGVAAALRGEAQGDADTTRVAEILAVA
QRPLIVAGCSLGVADIIEAAAAIASALGAKARIVLLPPEANSIGLALLGGDGLDSAAALLERGAAKTAIVLENELFERAP
RASVERLFAAAKSVVALDSMASETTARASVALPVAPFTGCAGTFVNYEGRAQRFFAAVPPQDSAPSAWRRLDAFGAGDWH
SLDALIGDLIVEWPDLVGVADAAPNADFMMADGQVTRAPRPYSARTADDRAGQFADAVIPIDPDGPMTFGIKGARGTAVP
PPLITSYKTAGLHSANNVTRFMEEIGGPLRGGDPGAMLLKPNAAALIDPPPSEPVAGEGLLMVPLHDAFSGFELSRASAL
LAARAPAPRLLLHPDDAALHGLAPGAAVLIDGRACAATISLDASLPRGCVAISAGIDAPRGPLRRVRLEAAR
>Mature_871_residues
TKKIEIDGRIIEAKDDEDLLSACLTHGVDVPYFCWHGALGSVGACRQCAVKVYAGPNDTEGRIVMSCMTPVADVERVSVS
DPEAVAFRAQVIEWLMVNHPHDCPVCEEAGSCHLQDMTIATGHAIRRYRFDKRTHRNQDLGPLLTHEMNRCIACYRCTRF
YRDYAGGRDLDAFGAHDDVYFGRAEDGPLDSPFAGNLAEVCPTGVFNDKGWSQDYARKWDMRATPSICPHCSLGCNILVD
QRDGRVKRVQNRYHGALNGYFICDRGRYGPLHVVSDKRLLTPLMQGEAASEADACAAAHAVVAEGAIGIGSPRASLEANY
ALQRLVGPERFFAGVSDAEATMVRRIVAIVRAGPATVASLADVERADAVLVLGDDLTNASPRLALALRQTARGAERDLAE
QKGVPRWLDPAVRTAGEGRRSPIALVTPVADPLDHIAALSLRRDPQAIAALGAGVAAALRGEAQGDADTTRVAEILAVAQ
RPLIVAGCSLGVADIIEAAAAIASALGAKARIVLLPPEANSIGLALLGGDGLDSAAALLERGAAKTAIVLENELFERAPR
ASVERLFAAAKSVVALDSMASETTARASVALPVAPFTGCAGTFVNYEGRAQRFFAAVPPQDSAPSAWRRLDAFGAGDWHS
LDALIGDLIVEWPDLVGVADAAPNADFMMADGQVTRAPRPYSARTADDRAGQFADAVIPIDPDGPMTFGIKGARGTAVPP
PLITSYKTAGLHSANNVTRFMEEIGGPLRGGDPGAMLLKPNAAALIDPPPSEPVAGEGLLMVPLHDAFSGFELSRASALL
AARAPAPRLLLHPDDAALHGLAPGAAVLIDGRACAATISLDASLPRGCVAISAGIDAPRGPLRRVRLEAAR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=285, Percent_Identity=32.280701754386, Blast_Score=180, Evalue=6e-45,
Organism=Escherichia coli, GI145693161, Length=889, Percent_Identity=42.1822272215973, Blast_Score=680, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565758, Length=665, Percent_Identity=27.8195488721804, Blast_Score=189, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI32566231, Length=636, Percent_Identity=27.8301886792453, Blast_Score=179, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI193209088, Length=253, Percent_Identity=33.9920948616601, Blast_Score=149, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24640559, Length=414, Percent_Identity=30.1932367149758, Blast_Score=173, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24640557, Length=414, Percent_Identity=30.1932367149758, Blast_Score=173, Evalue=5e-43,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574 [H]

Pfam domain/function: PF00111 Fer2; PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 91952; Mature: 91820

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKIEIDGRIIEAKDDEDLLSACLTHGVDVPYFCWHGALGSVGACRQCAVKVYAGPNDT
CCCEEEECCEEEECCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHCEEEEEECCCCC
EGRIVMSCMTPVADVERVSVSDPEAVAFRAQVIEWLMVNHPHDCPVCEEAGSCHLQDMTI
CCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEEEEE
ATGHAIRRYRFDKRTHRNQDLGPLLTHEMNRCIACYRCTRFYRDYAGGRDLDAFGAHDDV
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
YFGRAEDGPLDSPFAGNLAEVCPTGVFNDKGWSQDYARKWDMRATPSICPHCSLGCNILV
EECCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEE
DQRDGRVKRVQNRYHGALNGYFICDRGRYGPLHVVSDKRLLTPLMQGEAASEADACAAAH
ECCCCHHHHHHHHHCCCCCCEEEECCCCCCCEEEECCCHHHHHHHCCCCCCHHHHHHHHH
AVVAEGAIGIGSPRASLEANYALQRLVGPERFFAGVSDAEATMVRRIVAIVRAGPATVAS
HHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHH
LADVERADAVLVLGDDLTNASPRLALALRQTARGAERDLAEQKGVPRWLDPAVRTAGEGR
HHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHHHCHHHHHCCCCC
RSPIALVTPVADPLDHIAALSLRRDPQAIAALGAGVAAALRGEAQGDADTTRVAEILAVA
CCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
QRPLIVAGCSLGVADIIEAAAAIASALGAKARIVLLPPEANSIGLALLGGDGLDSAAALL
CCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHH
ERGAAKTAIVLENELFERAPRASVERLFAAAKSVVALDSMASETTARASVALPVAPFTGC
HCCCCCEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCC
AGTFVNYEGRAQRFFAAVPPQDSAPSAWRRLDAFGAGDWHSLDALIGDLIVEWPDLVGVA
CCCEECCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHCEEC
DAAPNADFMMADGQVTRAPRPYSARTADDRAGQFADAVIPIDPDGPMTFGIKGARGTAVP
CCCCCCCEEEECCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCC
PPLITSYKTAGLHSANNVTRFMEEIGGPLRGGDPGAMLLKPNAAALIDPPPSEPVAGEGL
CCHHHCCHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCE
LMVPLHDAFSGFELSRASALLAARAPAPRLLLHPDDAALHGLAPGAAVLIDGRACAATIS
EEEEECCCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHCCCCCCEEEECCCEEEEEEE
LDASLPRGCVAISAGIDAPRGPLRRVRLEAAR
ECCCCCCCEEEEECCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure 
TKKIEIDGRIIEAKDDEDLLSACLTHGVDVPYFCWHGALGSVGACRQCAVKVYAGPNDT
CCEEEECCEEEECCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHCEEEEEECCCCC
EGRIVMSCMTPVADVERVSVSDPEAVAFRAQVIEWLMVNHPHDCPVCEEAGSCHLQDMTI
CCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEEEEE
ATGHAIRRYRFDKRTHRNQDLGPLLTHEMNRCIACYRCTRFYRDYAGGRDLDAFGAHDDV
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
YFGRAEDGPLDSPFAGNLAEVCPTGVFNDKGWSQDYARKWDMRATPSICPHCSLGCNILV
EECCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEE
DQRDGRVKRVQNRYHGALNGYFICDRGRYGPLHVVSDKRLLTPLMQGEAASEADACAAAH
ECCCCHHHHHHHHHCCCCCCEEEECCCCCCCEEEECCCHHHHHHHCCCCCCHHHHHHHHH
AVVAEGAIGIGSPRASLEANYALQRLVGPERFFAGVSDAEATMVRRIVAIVRAGPATVAS
HHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHH
LADVERADAVLVLGDDLTNASPRLALALRQTARGAERDLAEQKGVPRWLDPAVRTAGEGR
HHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHHHCHHHHHCCCCC
RSPIALVTPVADPLDHIAALSLRRDPQAIAALGAGVAAALRGEAQGDADTTRVAEILAVA
CCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
QRPLIVAGCSLGVADIIEAAAAIASALGAKARIVLLPPEANSIGLALLGGDGLDSAAALL
CCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHH
ERGAAKTAIVLENELFERAPRASVERLFAAAKSVVALDSMASETTARASVALPVAPFTGC
HCCCCCEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCC
AGTFVNYEGRAQRFFAAVPPQDSAPSAWRRLDAFGAGDWHSLDALIGDLIVEWPDLVGVA
CCCEECCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHCEEC
DAAPNADFMMADGQVTRAPRPYSARTADDRAGQFADAVIPIDPDGPMTFGIKGARGTAVP
CCCCCCCEEEECCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCC
PPLITSYKTAGLHSANNVTRFMEEIGGPLRGGDPGAMLLKPNAAALIDPPPSEPVAGEGL
CCHHHCCHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCE
LMVPLHDAFSGFELSRASALLAARAPAPRLLLHPDDAALHGLAPGAAVLIDGRACAATIS
EEEEECCCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHCCCCCCEEEECCCEEEEEEE
LDASLPRGCVAISAGIDAPRGPLRRVRLEAAR
ECCCCCCCEEEEECCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12118882 [H]