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The map label for this gene is gstA [H]

Identifier: 86748421

GI number: 86748421

Start: 1478043

End: 1478729

Strand: Reverse

Name: gstA [H]

Synonym: RPB_1296

Alternate gene names: 86748421

Gene position: 1478729-1478043 (Counterclockwise)

Preceding gene: 86748428

Following gene: 86748420

Centisome position: 27.73

GC content: 64.63

Gene sequence:

>687_bases
ATGCCCGGACCACAGGCGAGCGAAACGACCGCGATGTACAAGCTCTATTCGATGCAGCGATCCGGCAACAGCTACAAGGC
GCGGCTTGCGCTGGCGTTTCTGGGTGCGCCCTATCGCGCGATCGAAGTCGATATCCTGCGCGGCGAGAGTCGCACGCCGG
AATTCCTCGCCAAGAATCCGAGCGGTCAGGTGCCGCTGCTGGAAGTCGCGCAAGGCCGCTATCTGGCCGAATCCAACGCG
ATTCTGTGGTACCTCGCCGTCGGCACTTCGCTGGCGCCGGATACGCGGATGGATCGCGCCGAAGCGCTGCAATGGATGTT
CTTCGAGCAGCATGCGCTGGAGCCGAATATCGGATCGGCTTACTTCTGGCTGTGCCTGGTGAAGGGCGGTCGCGACTTGC
AGACCCACGCACTCGAGGACTGGCTGGAGCGGGGCTACGCCGCGCTGCAGGTGATGGAAAATCACCTCAGGACTCACGAT
TTCGTGGCGGCCGGCCAGCTCACCATCGCCGACATCGCGCTGTACGGCTACACCCACGTCGCCGACCAGTGCGACTTCGA
CCTGTCGACCTTCCCGGCGGTCAACGCGTGGCTGCGGCGGGTCGAGCAGACGCCGGGCTTCATCACCATGGACTGGACGC
CGGATTCGGCGCCGCACGACCACGTCGATTTCGCCGCCGAGGCCTGA

Upstream 100 bases:

>100_bases
CGCGGTTGCACTGCGGCAAATGATTTCGACCCTTTCCATTGCTTGGGGCTTGCGACGCCTGCCGGTCGGCATCATTGTTT
AGCCGCGTTCGGGTCGGCAG

Downstream 100 bases:

>100_bases
ACGACTGGTATTTTCGCGCCGATTCCGCCGTCATTTTGCCACGATCGGCCCCGTGCTGCCCCATAAACGCCTGCGATTGC
AAGGATATTTGAGTGCTCGG

Product: glutathione S-transferase-like protein

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MPGPQASETTAMYKLYSMQRSGNSYKARLALAFLGAPYRAIEVDILRGESRTPEFLAKNPSGQVPLLEVAQGRYLAESNA
ILWYLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCLVKGGRDLQTHALEDWLERGYAALQVMENHLRTHD
FVAAGQLTIADIALYGYTHVADQCDFDLSTFPAVNAWLRRVEQTPGFITMDWTPDSAPHDHVDFAAEA

Sequences:

>Translated_228_residues
MPGPQASETTAMYKLYSMQRSGNSYKARLALAFLGAPYRAIEVDILRGESRTPEFLAKNPSGQVPLLEVAQGRYLAESNA
ILWYLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCLVKGGRDLQTHALEDWLERGYAALQVMENHLRTHD
FVAAGQLTIADIALYGYTHVADQCDFDLSTFPAVNAWLRRVEQTPGFITMDWTPDSAPHDHVDFAAEA
>Mature_227_residues
PGPQASETTAMYKLYSMQRSGNSYKARLALAFLGAPYRAIEVDILRGESRTPEFLAKNPSGQVPLLEVAQGRYLAESNAI
LWYLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCLVKGGRDLQTHALEDWLERGYAALQVMENHLRTHDF
VAAGQLTIADIALYGYTHVADQCDFDLSTFPAVNAWLRRVEQTPGFITMDWTPDSAPHDHVDFAAEA

Specific function: Unknown

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4503481, Length=201, Percent_Identity=27.8606965174129, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1788640, Length=191, Percent_Identity=28.7958115183246, Blast_Score=73, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24654992, Length=196, Percent_Identity=32.6530612244898, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17864596, Length=197, Percent_Identity=29.9492385786802, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19922532, Length=200, Percent_Identity=31, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20130115, Length=196, Percent_Identity=30.1020408163265, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24654983, Length=198, Percent_Identity=30.3030303030303, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17933730, Length=198, Percent_Identity=28.7878787878788, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI19922526, Length=207, Percent_Identity=28.0193236714976, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17864594, Length=197, Percent_Identity=29.9492385786802, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571670, Length=178, Percent_Identity=29.2134831460674, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24654979, Length=196, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24651001, Length=189, Percent_Identity=28.042328042328, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24651003, Length=189, Percent_Identity=28.042328042328, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19922528, Length=203, Percent_Identity=31.0344827586207, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 25531; Mature: 25400

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGPQASETTAMYKLYSMQRSGNSYKARLALAFLGAPYRAIEVDILRGESRTPEFLAKNP
CCCCCCCHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCEEEEEEEEECCCCCCHHHCCCC
SGQVPLLEVAQGRYLAESNAILWYLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSA
CCCCCHHHHHCCCEEECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
YFWLCLVKGGRDLQTHALEDWLERGYAALQVMENHLRTHDFVAAGQLTIADIALYGYTHV
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEHHHHHHHHHH
ADQCDFDLSTFPAVNAWLRRVEQTPGFITMDWTPDSAPHDHVDFAAEA
HCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PGPQASETTAMYKLYSMQRSGNSYKARLALAFLGAPYRAIEVDILRGESRTPEFLAKNP
CCCCCCHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCEEEEEEEEECCCCCCHHHCCCC
SGQVPLLEVAQGRYLAESNAILWYLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSA
CCCCCHHHHHCCCEEECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
YFWLCLVKGGRDLQTHALEDWLERGYAALQVMENHLRTHDFVAAGQLTIADIALYGYTHV
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEHHHHHHHHHH
ADQCDFDLSTFPAVNAWLRRVEQTPGFITMDWTPDSAPHDHVDFAAEA
HCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA