Click here to switch to the map view.

The map label for this gene is mmgC [H]

Identifier: 86748363

GI number: 86748363

Start: 1416968

End: 1418164

Strand: Reverse

Name: mmgC [H]

Synonym: RPB_1238

Alternate gene names: 86748363

Gene position: 1418164-1416968 (Counterclockwise)

Preceding gene: 86748364

Following gene: 86748356

Centisome position: 26.6

GC content: 66.17

Gene sequence:

>1197_bases
ATGGACATGACCTTCGGCGATTCCGAGCTCGCCTTTCAGCAGGAGGTCCGCGATTTCATCGCGGCCAATCTCACGCCCGA
CATGAAGCGCGCGGAGTCGCTCAACGCCTCGGTGTTCTCCGAGCCGGAGACCGGCGTGCCGTGGCAACGCGCCCTCAACG
CGAAGGGCTGGGGCGCCCCCGGCTGGCCGGTCGAATATGGCGGCACCGGCTGGACACCGGCGCAGCGCTGGATTTTCGAG
ACCGAATGCGCGCATGCGGGCGTGCCGTCGCCGACGCCGATGGGCGTCAAGATGGTCGGCCCCGTCATCATCGGCTTCGG
CTCGCCGGAGCAGAAGAACTACTTCCTGCCGCGGATTCTGTCCTGCGAGGATTATTGGTGTCAGGGCTATTCGGAGCCCG
GTTCGGGCTCGGACCTGTCGTCGCTGAAGACCCGCGCGGTCCGCGACGGCGACGAGTACGTCATCAACGGCACCAAGATC
TGGACCACCCACGCCCACAACGCCAACATGATGTTCGCGCTGGTGCGCACCAGCGACGAGCCGCGGCAGCAGGACGGCAT
CAGCTTCGTGCTGATCGACATGAAGAGCCCCGGCATTACCATCCGCCCGATCCTGACGATCGGCGGCGATCACGAGGTCA
ACCAGGTGTTCTTCGACGACGTCCGGATTCCGGCATCGAACCTGGTCGGCGAGGAAGGCAAGGGCTGGACCTACGGCAAG
TACCTACTCGAATTCGAACGCGGTTCCGGCATCGCCTCGGCGAAGCTCCGCAAGGCGCTGCACAGGACGGCGGCGTTCGC
CGAGTCGGAGGCGACCGGACGGGCGATCGAGGATCCGGACATCGCGATCCGGATGTCGGAGGCCGAGGTCGATATCGACG
CGCTGGAAATGACCGAGCTGCGGGTGCTCTCCGCGCTGCAGAACGGCCAGAACCCCGGCGCGGTGTCGTCGATCCTCAAG
CTGCGCACCAGCGAGATCTACCAGGCGGTGAGCCGCCTCGGCGTCGACGTGATCGGCACCGACGGCCTCTATGTCGAACC
GACCCGCCCGCTGCACCGGCTCAACGCCCCGCCGGCGATTCCCGAGGACGAACTCGCCGTGATGCCGACACACCTCAACG
GCCGCGCCTACACCATCTTCGGCGGCACCTCCGAGATCCAGCGCGACATCATCAGCAAGCTGGTGCTGGGGTTGTAG

Upstream 100 bases:

>100_bases
CCTGCTGGCGTTCGAGACGCTGTTCGGCGGCAGCACCCATCATTATCGCCGCCACGCCGCGCTCAGCGGCCGGCCTGTTT
AAGCAAAGCGAGGCATCGAC

Downstream 100 bases:

>100_bases
GCCGCTCGTCAACGACGAGTCGAAGCGTCATCCTGAGGTGCGTGTCGGCCGCGCGTCGCGCGGTCGACGCGCCTCGAAGG
ATGGCCGCACGCGCCGGTCT

Product: Acyl-CoA dehydrogenase-like

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDMTFGDSELAFQQEVRDFIAANLTPDMKRAESLNASVFSEPETGVPWQRALNAKGWGAPGWPVEYGGTGWTPAQRWIFE
TECAHAGVPSPTPMGVKMVGPVIIGFGSPEQKNYFLPRILSCEDYWCQGYSEPGSGSDLSSLKTRAVRDGDEYVINGTKI
WTTHAHNANMMFALVRTSDEPRQQDGISFVLIDMKSPGITIRPILTIGGDHEVNQVFFDDVRIPASNLVGEEGKGWTYGK
YLLEFERGSGIASAKLRKALHRTAAFAESEATGRAIEDPDIAIRMSEAEVDIDALEMTELRVLSALQNGQNPGAVSSILK
LRTSEIYQAVSRLGVDVIGTDGLYVEPTRPLHRLNAPPAIPEDELAVMPTHLNGRAYTIFGGTSEIQRDIISKLVLGL

Sequences:

>Translated_398_residues
MDMTFGDSELAFQQEVRDFIAANLTPDMKRAESLNASVFSEPETGVPWQRALNAKGWGAPGWPVEYGGTGWTPAQRWIFE
TECAHAGVPSPTPMGVKMVGPVIIGFGSPEQKNYFLPRILSCEDYWCQGYSEPGSGSDLSSLKTRAVRDGDEYVINGTKI
WTTHAHNANMMFALVRTSDEPRQQDGISFVLIDMKSPGITIRPILTIGGDHEVNQVFFDDVRIPASNLVGEEGKGWTYGK
YLLEFERGSGIASAKLRKALHRTAAFAESEATGRAIEDPDIAIRMSEAEVDIDALEMTELRVLSALQNGQNPGAVSSILK
LRTSEIYQAVSRLGVDVIGTDGLYVEPTRPLHRLNAPPAIPEDELAVMPTHLNGRAYTIFGGTSEIQRDIISKLVLGL
>Mature_398_residues
MDMTFGDSELAFQQEVRDFIAANLTPDMKRAESLNASVFSEPETGVPWQRALNAKGWGAPGWPVEYGGTGWTPAQRWIFE
TECAHAGVPSPTPMGVKMVGPVIIGFGSPEQKNYFLPRILSCEDYWCQGYSEPGSGSDLSSLKTRAVRDGDEYVINGTKI
WTTHAHNANMMFALVRTSDEPRQQDGISFVLIDMKSPGITIRPILTIGGDHEVNQVFFDDVRIPASNLVGEEGKGWTYGK
YLLEFERGSGIASAKLRKALHRTAAFAESEATGRAIEDPDIAIRMSEAEVDIDALEMTELRVLSALQNGQNPGAVSSILK
LRTSEIYQAVSRLGVDVIGTDGLYVEPTRPLHRLNAPPAIPEDELAVMPTHLNGRAYTIFGGTSEIQRDIISKLVLGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=397, Percent_Identity=28.9672544080605, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI187960098, Length=406, Percent_Identity=25.615763546798, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4557231, Length=406, Percent_Identity=25.615763546798, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4501857, Length=407, Percent_Identity=24.3243243243243, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI7656849, Length=411, Percent_Identity=24.330900243309, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4501859, Length=242, Percent_Identity=29.3388429752066, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI226958412, Length=392, Percent_Identity=23.7244897959184, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=24.633431085044, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI21361497, Length=241, Percent_Identity=28.6307053941909, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4557235, Length=180, Percent_Identity=32.2222222222222, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI76496475, Length=180, Percent_Identity=32.2222222222222, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI38505218, Length=256, Percent_Identity=26.5625, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87081958, Length=355, Percent_Identity=24.2253521126761, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786223, Length=251, Percent_Identity=25.8964143426295, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=411, Percent_Identity=24.5742092457421, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17569725, Length=388, Percent_Identity=26.5463917525773, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17538396, Length=252, Percent_Identity=30.5555555555556, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=344, Percent_Identity=28.4883720930233, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17551932, Length=351, Percent_Identity=27.0655270655271, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17534899, Length=414, Percent_Identity=25.1207729468599, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17506239, Length=351, Percent_Identity=28.7749287749288, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI32563615, Length=185, Percent_Identity=37.2972972972973, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=295, Percent_Identity=26.7796610169492, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=192, Percent_Identity=32.8125, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71982178, Length=258, Percent_Identity=24.8062015503876, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71985184, Length=149, Percent_Identity=30.8724832214765, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=145, Percent_Identity=31.0344827586207, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534353, Length=410, Percent_Identity=22.4390243902439, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24660351, Length=311, Percent_Identity=29.2604501607717, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI281363737, Length=223, Percent_Identity=30.9417040358744, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356377, Length=404, Percent_Identity=26.7326732673267, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21355753, Length=245, Percent_Identity=29.7959183673469, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24666513, Length=160, Percent_Identity=36.875, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646207, Length=401, Percent_Identity=25.4364089775561, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43558; Mature: 43558

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMTFGDSELAFQQEVRDFIAANLTPDMKRAESLNASVFSEPETGVPWQRALNAKGWGAP
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCCCCHHHHCCCCCCCCC
GWPVEYGGTGWTPAQRWIFETECAHAGVPSPTPMGVKMVGPVIIGFGSPEQKNYFLPRIL
CCCEECCCCCCCHHHHEEEEECHHHCCCCCCCCCCEEEECEEEEECCCCCCCCCCCCEEE
SCEDYWCQGYSEPGSGSDLSSLKTRAVRDGDEYVINGTKIWTTHAHNANMMFALVRTSDE
CCCHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECEEEEEEECCCCCEEEEEEECCCC
PRQQDGISFVLIDMKSPGITIRPILTIGGDHEVNQVFFDDVRIPASNLVGEEGKGWTYGK
CHHHCCCEEEEEEECCCCEEEEEEEEECCCCCCCCEEECCCCCCHHHHCCCCCCCCEEEE
YLLEFERGSGIASAKLRKALHRTAAFAESEATGRAIEDPDIAIRMSEAEVDIDALEMTEL
EEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHH
RVLSALQNGQNPGAVSSILKLRTSEIYQAVSRLGVDVIGTDGLYVEPTRPLHRLNAPPAI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCCCHHHHCCCCCCC
PEDELAVMPTHLNGRAYTIFGGTSEIQRDIISKLVLGL
CCCCEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDMTFGDSELAFQQEVRDFIAANLTPDMKRAESLNASVFSEPETGVPWQRALNAKGWGAP
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCCCCHHHHCCCCCCCCC
GWPVEYGGTGWTPAQRWIFETECAHAGVPSPTPMGVKMVGPVIIGFGSPEQKNYFLPRIL
CCCEECCCCCCCHHHHEEEEECHHHCCCCCCCCCCEEEECEEEEECCCCCCCCCCCCEEE
SCEDYWCQGYSEPGSGSDLSSLKTRAVRDGDEYVINGTKIWTTHAHNANMMFALVRTSDE
CCCHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECEEEEEEECCCCCEEEEEEECCCC
PRQQDGISFVLIDMKSPGITIRPILTIGGDHEVNQVFFDDVRIPASNLVGEEGKGWTYGK
CHHHCCCEEEEEEECCCCEEEEEEEEECCCCCCCCEEECCCCCCHHHHCCCCCCCCEEEE
YLLEFERGSGIASAKLRKALHRTAAFAESEATGRAIEDPDIAIRMSEAEVDIDALEMTEL
EEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHH
RVLSALQNGQNPGAVSSILKLRTSEIYQAVSRLGVDVIGTDGLYVEPTRPLHRLNAPPAI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCCCHHHHCCCCCCC
PEDELAVMPTHLNGRAYTIFGGTSEIQRDIISKLVLGL
CCCCEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]