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The map label for this gene is aroC [H]

Identifier: 86748337

GI number: 86748337

Start: 1385868

End: 1386953

Strand: Direct

Name: aroC [H]

Synonym: RPB_1212

Alternate gene names: 86748337

Gene position: 1385868-1386953 (Clockwise)

Preceding gene: 86748336

Following gene: 86748338

Centisome position: 25.99

GC content: 68.51

Gene sequence:

>1086_bases
ATGTCGTTCAATACCTTCGGCCACATGTTTCGTGTCACCACGTTCGGCGAAAGCCACGGGGTGGCGATCGGCTGCGTGGT
CGACGGCTGTCCGCCGCTGATCCCGCTGACCGAGGCCGACATCCAGGGCGACCTCGACCGCCGCCGGCCGGGGCAGTCGC
GCTTCACCACGCAGCGCCAGGAAGCCGACCAGGTGAAGATCCTGTCCGGCGTGATGGCGCATCCGGAGACCGGCGTGCAG
GTCACCACCGGGACGCCGATCGCGCTCTTGATCGAGAACACCGACCAGCGCTCCAAGGATTATTCCGAGATCCAGAACAA
GTTTCGGCCCGGCCATGCCGACTTCACCTATGAGGCGAAATACGGCATCCGCGACTATCGCGGCGGCGGCCGCTCCTCGG
CGCGCGAGACCGCGACCCGCGTCGCCGCCGGCGCGGTGGCGCGCAAGGTGATCGCCGGCATGACCGTGCGCGGCGCGCTG
GTGCAGATCGGCCCGCACCAGATCGACCGCGACAAATGGGACTGGGCCGAGATCGGCAACAACCCGTTCTTCTGCCCCGA
CAAGGACAAGGCGGCGTTCTTCGCCGATTATCTCGACGGCATCCGCAAGAGCGGCTCGTCGATCGGCGCGGTGATCGAAG
TGGTCGCCGAAGGCGTGCCCGCGGGCCTCGGCGCGCCGATCTACGCCAAGCTCGACACCGACCTCGCCGCGGCGCTGATG
AGCATCAACGCGGTCAAGGGCGTCGAGATCGGCGACGGCTTCGCCACCGCGGCGCTGACCGGCGAGGAGAACGCTGACGA
GATGCGGATGGGCAATGCCGGCCCGCAATTTCTGTCGAACCATGCGGGCGGCATTTTGGGCGGCATCTCCACGGGGCAGC
CGGTGGTGGCGCGGTTCGCGGTGAAGCCGACCTCGTCGATCCTGTCGCCGCGCAAGACCATCGATCGCGCCGGCCACGAC
ACCGATATCCTGACCAAGGGCCGCCACGACCCCTGCGTCGGCATCCGCGCGGTCCCGGTCGGCGAGGCGATGGTCGCCTG
CGTGCTGGCCGATCATCTGCTGCGCCACCGCGGGCAGGTCGGCTAG

Upstream 100 bases:

>100_bases
CTTCGCTCGCCACCCTCTCCCACAAGGGGAGAGGGTCGGTTTGACCCTGTCCGGCCGGCGCGTTACCACACCGGCGCATG
TCTCGAGAGGCGGGTCCGCC

Downstream 100 bases:

>100_bases
ATCGCCTCGGAGGCGCCGCGGCGTGTGCGCCGGCAGCGGCATGGCTGGGGATCTGCCATGAACGGTACCCCGGTCCCAAA
GCCGATGCGTTCCGCTAGGA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSFNTFGHMFRVTTFGESHGVAIGCVVDGCPPLIPLTEADIQGDLDRRRPGQSRFTTQRQEADQVKILSGVMAHPETGVQ
VTTGTPIALLIENTDQRSKDYSEIQNKFRPGHADFTYEAKYGIRDYRGGGRSSARETATRVAAGAVARKVIAGMTVRGAL
VQIGPHQIDRDKWDWAEIGNNPFFCPDKDKAAFFADYLDGIRKSGSSIGAVIEVVAEGVPAGLGAPIYAKLDTDLAAALM
SINAVKGVEIGDGFATAALTGEENADEMRMGNAGPQFLSNHAGGILGGISTGQPVVARFAVKPTSSILSPRKTIDRAGHD
TDILTKGRHDPCVGIRAVPVGEAMVACVLADHLLRHRGQVG

Sequences:

>Translated_361_residues
MSFNTFGHMFRVTTFGESHGVAIGCVVDGCPPLIPLTEADIQGDLDRRRPGQSRFTTQRQEADQVKILSGVMAHPETGVQ
VTTGTPIALLIENTDQRSKDYSEIQNKFRPGHADFTYEAKYGIRDYRGGGRSSARETATRVAAGAVARKVIAGMTVRGAL
VQIGPHQIDRDKWDWAEIGNNPFFCPDKDKAAFFADYLDGIRKSGSSIGAVIEVVAEGVPAGLGAPIYAKLDTDLAAALM
SINAVKGVEIGDGFATAALTGEENADEMRMGNAGPQFLSNHAGGILGGISTGQPVVARFAVKPTSSILSPRKTIDRAGHD
TDILTKGRHDPCVGIRAVPVGEAMVACVLADHLLRHRGQVG
>Mature_360_residues
SFNTFGHMFRVTTFGESHGVAIGCVVDGCPPLIPLTEADIQGDLDRRRPGQSRFTTQRQEADQVKILSGVMAHPETGVQV
TTGTPIALLIENTDQRSKDYSEIQNKFRPGHADFTYEAKYGIRDYRGGGRSSARETATRVAAGAVARKVIAGMTVRGALV
QIGPHQIDRDKWDWAEIGNNPFFCPDKDKAAFFADYLDGIRKSGSSIGAVIEVVAEGVPAGLGAPIYAKLDTDLAAALMS
INAVKGVEIGDGFATAALTGEENADEMRMGNAGPQFLSNHAGGILGGISTGQPVVARFAVKPTSSILSPRKTIDRAGHDT
DILTKGRHDPCVGIRAVPVGEAMVACVLADHLLRHRGQVG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=362, Percent_Identity=63.8121546961326, Blast_Score=438, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321290, Length=374, Percent_Identity=42.5133689839572, Blast_Score=282, Evalue=4e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 38378; Mature: 38247

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNTFGHMFRVTTFGESHGVAIGCVVDGCPPLIPLTEADIQGDLDRRRPGQSRFTTQRQ
CCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHH
EADQVKILSGVMAHPETGVQVTTGTPIALLIENTDQRSKDYSEIQNKFRPGHADFTYEAK
HHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEC
YGIRDYRGGGRSSARETATRVAAGAVARKVIAGMTVRGALVQIGPHQIDRDKWDWAEIGN
CCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCEEEEECCCCCCCCCCCHHHCCC
NPFFCPDKDKAAFFADYLDGIRKSGSSIGAVIEVVAEGVPAGLGAPIYAKLDTDLAAALM
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHH
SINAVKGVEIGDGFATAALTGEENADEMRMGNAGPQFLSNHAGGILGGISTGQPVVARFA
HHHHHCCCCCCCCEEEEEECCCCCHHHHHCCCCCHHHHHHCCCCEEECCCCCCCEEEEEE
VKPTSSILSPRKTIDRAGHDTDILTKGRHDPCVGIRAVPVGEAMVACVLADHLLRHRGQV
ECCHHHHHCCHHHHHHCCCCCHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCC
G
C
>Mature Secondary Structure 
SFNTFGHMFRVTTFGESHGVAIGCVVDGCPPLIPLTEADIQGDLDRRRPGQSRFTTQRQ
CCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHH
EADQVKILSGVMAHPETGVQVTTGTPIALLIENTDQRSKDYSEIQNKFRPGHADFTYEAK
HHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEC
YGIRDYRGGGRSSARETATRVAAGAVARKVIAGMTVRGALVQIGPHQIDRDKWDWAEIGN
CCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCEEEEECCCCCCCCCCCHHHCCC
NPFFCPDKDKAAFFADYLDGIRKSGSSIGAVIEVVAEGVPAGLGAPIYAKLDTDLAAALM
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHH
SINAVKGVEIGDGFATAALTGEENADEMRMGNAGPQFLSNHAGGILGGISTGQPVVARFA
HHHHHCCCCCCCCEEEEEECCCCCHHHHHCCCCCHHHHHHCCCCEEECCCCCCCEEEEEE
VKPTSSILSPRKTIDRAGHDTDILTKGRHDPCVGIRAVPVGEAMVACVLADHLLRHRGQV
ECCHHHHHCCHHHHHHCCCCCHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA