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The map label for this gene is bioH [H]

Identifier: 86748333

GI number: 86748333

Start: 1381257

End: 1382078

Strand: Reverse

Name: bioH [H]

Synonym: RPB_1208

Alternate gene names: 86748333

Gene position: 1382078-1381257 (Counterclockwise)

Preceding gene: 86748334

Following gene: 86748330

Centisome position: 25.92

GC content: 70.19

Gene sequence:

>822_bases
ATGCAGACCCAGACGATCGAGACGTCCATTGGACGGATCGCCTACCGCCAGTCCGCCGGCAGCGGACCGACCATCGTCCT
CATTCACGGCAATTCGGCCTCCTCACGCGCCTTCGCGCCGCAGCTCGACAGCCCGCTCGGCGCCAAATATCGCATCCTGG
TGCCCGATCTGCCCGGCCACGGCGAGTCGGACGATGCGGCCGATCCGGCCGGCACCTACAACCTGCCCGGCTATGCCGCC
GTTTTGCGCCAGGTCGTGGCCAGGCTCGACGCCGCAGATGCGATTTTCGTCGGCTGGAGCCTCGGCGGGCACATCGTGCT
GGAGGCCGCGCCCGACCTCGCACAGGCCCGCGGCTTTGCGATCTTCGGCGCCCCGCCGATCAGCTTTCCGCCGGCGATGG
ACCGGGCGTTCCTGCCGACGCCGGCGATGGCCTACACCTTCCAGCCCGAACTCGACGAAGACCAGGCGCGCGCCTATGTC
GCCGCCGCGTTCCGGCCGGGCGTCGGCGAACTGCCGGCGGAGATGGTGGCCGACGTGCTGCGCACCGACGGCCGCGCCCG
CGGCCAGCTCGCCGCCAGCATCCGGCCCGGCGGCTATCGCGACGAGGTGGCTGTCGCCGCCGACCTGAAGCAGCCGCTCG
CCGTGCTGCACGGCGCCGAGGAACAGCTCGTCAACGGCGCCTATTTCGACACGCTGACGATGCCGACCTTGTGGCGTGGC
CGGGTGCAGGTGATCGACGACGCCGGCCATCTGCCGCAATGGGAACAGGCGAAGCGCTTCAACGCGCTGCTCGATGCGTT
CGTGACGGAGGCGAACGCTTAG

Upstream 100 bases:

>100_bases
CCCCTTCCAGGCCGAAGACCTGCCGCAGCCGCGGCGCGGCCTTCCCAAATCCGGTACGCTGGTATTGTATCCCCACCGCA
AGTGCGAAGGGACACCATCC

Downstream 100 bases:

>100_bases
ATAAAGCCGCCGCACCAGCCGTCATTGCGAGCGAAGCGAAGCAATCCAGCTCAGTGCACCGGGCCGGATTGCGTCGTCGC
TTCGCTCCTCGCAATGACGA

Product: Alpha/beta hydrolase

Products: NA

Alternate protein names: Biotin synthesis protein BioH [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MQTQTIETSIGRIAYRQSAGSGPTIVLIHGNSASSRAFAPQLDSPLGAKYRILVPDLPGHGESDDAADPAGTYNLPGYAA
VLRQVVARLDAADAIFVGWSLGGHIVLEAAPDLAQARGFAIFGAPPISFPPAMDRAFLPTPAMAYTFQPELDEDQARAYV
AAAFRPGVGELPAEMVADVLRTDGRARGQLAASIRPGGYRDEVAVAADLKQPLAVLHGAEEQLVNGAYFDTLTMPTLWRG
RVQVIDDAGHLPQWEQAKRFNALLDAFVTEANA

Sequences:

>Translated_273_residues
MQTQTIETSIGRIAYRQSAGSGPTIVLIHGNSASSRAFAPQLDSPLGAKYRILVPDLPGHGESDDAADPAGTYNLPGYAA
VLRQVVARLDAADAIFVGWSLGGHIVLEAAPDLAQARGFAIFGAPPISFPPAMDRAFLPTPAMAYTFQPELDEDQARAYV
AAAFRPGVGELPAEMVADVLRTDGRARGQLAASIRPGGYRDEVAVAADLKQPLAVLHGAEEQLVNGAYFDTLTMPTLWRG
RVQVIDDAGHLPQWEQAKRFNALLDAFVTEANA
>Mature_273_residues
MQTQTIETSIGRIAYRQSAGSGPTIVLIHGNSASSRAFAPQLDSPLGAKYRILVPDLPGHGESDDAADPAGTYNLPGYAA
VLRQVVARLDAADAIFVGWSLGGHIVLEAAPDLAQARGFAIFGAPPISFPPAMDRAFLPTPAMAYTFQPELDEDQARAYV
AAAFRPGVGELPAEMVADVLRTDGRARGQLAASIRPGGYRDEVAVAADLKQPLAVLHGAEEQLVNGAYFDTLTMPTLWRG
RVQVIDDAGHLPQWEQAKRFNALLDAFVTEANA

Specific function: Shows carboxylesterase activity with a preference for short chain fatty acid esters (acyl chain length of up to 6 carbons). Also displays a weak thioesterase activity. Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010076 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 29031; Mature: 29031

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTQTIETSIGRIAYRQSAGSGPTIVLIHGNSASSRAFAPQLDSPLGAKYRILVPDLPGH
CCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
GESDDAADPAGTYNLPGYAAVLRQVVARLDAADAIFVGWSLGGHIVLEAAPDLAQARGFA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHHCCEE
IFGAPPISFPPAMDRAFLPTPAMAYTFQPELDEDQARAYVAAAFRPGVGELPAEMVADVL
EECCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHEEEEECCCCCCCCCCHHHHHHHH
RTDGRARGQLAASIRPGGYRDEVAVAADLKQPLAVLHGAEEQLVNGAYFDTLTMPTLWRG
HCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCHHHHCCCCHHHCC
RVQVIDDAGHLPQWEQAKRFNALLDAFVTEANA
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQTQTIETSIGRIAYRQSAGSGPTIVLIHGNSASSRAFAPQLDSPLGAKYRILVPDLPGH
CCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
GESDDAADPAGTYNLPGYAAVLRQVVARLDAADAIFVGWSLGGHIVLEAAPDLAQARGFA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHHCCEE
IFGAPPISFPPAMDRAFLPTPAMAYTFQPELDEDQARAYVAAAFRPGVGELPAEMVADVL
EECCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHEEEEECCCCCCCCCCHHHHHHHH
RTDGRARGQLAASIRPGGYRDEVAVAADLKQPLAVLHGAEEQLVNGAYFDTLTMPTLWRG
HCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCHHHHCCCCHHHCC
RVQVIDDAGHLPQWEQAKRFNALLDAFVTEANA
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA