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The map label for this gene is etfA [H]

Identifier: 86747946

GI number: 86747946

Start: 935700

End: 936650

Strand: Direct

Name: etfA [H]

Synonym: RPB_0820

Alternate gene names: 86747946

Gene position: 935700-936650 (Clockwise)

Preceding gene: 86747945

Following gene: 86747947

Centisome position: 17.55

GC content: 67.19

Gene sequence:

>951_bases
ATGGCCACGCTGCTGATTGCCGAACACGACCACGCTCAGCTCAAGGATGCGACCAACAAGGCGCTGACCGCGGCAGCCGC
TCTCGGCGCCGAGGTTCACGTCCTGGTCGCCGGTGGTGGCGAGGGCACCAAGGCGGCCGCCGAAGCCGCTGCGAAGCTGC
AGGGCGTCGCCAAGGTGCTGCTGGCGGATGCGCCGCTCTATGAGCACGATCTCGCCGAGCCGCTGGCGGCGCTGATCGTG
TCGCTGGCGCCGAACTACGACGCGATCGTCGCGCCCGCGACCTCGCGCTTCAAGAACGTGATGCCGCGCGTCGCCGCTTT
GCTCGACGTCATGCAGGTGTCGGAGATCATCAAGGTGATCGCGCCCGACACCTATGAGCGGCCGATCTATGCGGGCAACG
CGATCCAGACCGTGAAGTCGAAGGACGCCAAGAAGGTGATCACGGTCCGCACCTCGACCTTCCAGGCGACCGGCGAGGGC
GGCAGCGCCGCGATCGAGCCGGTGGCGGCTGCGGCGGATCCGGGCCTCTCCACCTTCGTCGGCGAGGAGGTCGCCAAGAG
CGACCGTCCGGAACTGGCCTCGGCCAAGATCATCGTCTCCGGCGGCCGCGCGATGCAGAGCCGCGAGAACTTCACCAAAT
ACATCGAGCCGCTCGCCGACAAGCTCGGCGCCGGTGTCGGCGCCTCGCGCGCCGCGGTCGATGCCGGCTACGCGCCGAAC
GACTGGCAGGTCGGCCAGACCGGCAAGGTGGTGGCGCCGGAGCTGTACATCGCGATCGGCATTTCCGGCGCGATCCAGCA
TCTCGCCGGCATGAAGGACTCCAAGGTGATCGTCGCGATCAACAAGGACGAAGACGCGCCGATCTTCCAGGTCGCCGATT
ATGGTCTGGTCGCCGATCTGTATCAGGCGGTACCGGAACTGACCGACGAACTGGGCAAGCTCGGCAAGTAG

Upstream 100 bases:

>100_bases
TCCTCAAGACCGTCGAGCCGAGCGGCCGCAAGGCCGGCGTCAAGGTCAAGGACGTCGCCGAACTGGTCTCCAAACTCAAG
AACGAAGCGGGTGTTATCTG

Downstream 100 bases:

>100_bases
ACGGCGGCTCGCGCACGGATCCGGCTGCGGCCGGGTCCGTTGCCGAAGCCTTCATTTTTGACGTGATACGATCGCCGCGC
CGGTGCAACGGATGGCGGCG

Product: electron transfer flavoprotein, alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MATLLIAEHDHAQLKDATNKALTAAAALGAEVHVLVAGGGEGTKAAAEAAAKLQGVAKVLLADAPLYEHDLAEPLAALIV
SLAPNYDAIVAPATSRFKNVMPRVAALLDVMQVSEIIKVIAPDTYERPIYAGNAIQTVKSKDAKKVITVRTSTFQATGEG
GSAAIEPVAAAADPGLSTFVGEEVAKSDRPELASAKIIVSGGRAMQSRENFTKYIEPLADKLGAGVGASRAAVDAGYAPN
DWQVGQTGKVVAPELYIAIGISGAIQHLAGMKDSKVIVAINKDEDAPIFQVADYGLVADLYQAVPELTDELGKLGK

Sequences:

>Translated_316_residues
MATLLIAEHDHAQLKDATNKALTAAAALGAEVHVLVAGGGEGTKAAAEAAAKLQGVAKVLLADAPLYEHDLAEPLAALIV
SLAPNYDAIVAPATSRFKNVMPRVAALLDVMQVSEIIKVIAPDTYERPIYAGNAIQTVKSKDAKKVITVRTSTFQATGEG
GSAAIEPVAAAADPGLSTFVGEEVAKSDRPELASAKIIVSGGRAMQSRENFTKYIEPLADKLGAGVGASRAAVDAGYAPN
DWQVGQTGKVVAPELYIAIGISGAIQHLAGMKDSKVIVAINKDEDAPIFQVADYGLVADLYQAVPELTDELGKLGK
>Mature_315_residues
ATLLIAEHDHAQLKDATNKALTAAAALGAEVHVLVAGGGEGTKAAAEAAAKLQGVAKVLLADAPLYEHDLAEPLAALIVS
LAPNYDAIVAPATSRFKNVMPRVAALLDVMQVSEIIKVIAPDTYERPIYAGNAIQTVKSKDAKKVITVRTSTFQATGEGG
SAAIEPVAAAADPGLSTFVGEEVAKSDRPELASAKIIVSGGRAMQSRENFTKYIEPLADKLGAGVGASRAAVDAGYAPND
WQVGQTGKVVAPELYIAIGISGAIQHLAGMKDSKVIVAINKDEDAPIFQVADYGLVADLYQAVPELTDELGKLGK

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=317, Percent_Identity=54.5741324921136, Blast_Score=309, Evalue=2e-84,
Organism=Homo sapiens, GI189181759, Length=277, Percent_Identity=55.5956678700361, Blast_Score=288, Evalue=5e-78,
Organism=Escherichia coli, GI1786226, Length=198, Percent_Identity=35.3535353535354, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1787990, Length=260, Percent_Identity=32.3076923076923, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082157, Length=218, Percent_Identity=31.651376146789, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=314, Percent_Identity=57.3248407643312, Blast_Score=322, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6325261, Length=285, Percent_Identity=48.4210526315789, Blast_Score=253, Evalue=3e-68,
Organism=Drosophila melanogaster, GI17136898, Length=315, Percent_Identity=58.4126984126984, Blast_Score=323, Evalue=9e-89,
Organism=Drosophila melanogaster, GI24652801, Length=315, Percent_Identity=58.4126984126984, Blast_Score=323, Evalue=9e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32674; Mature: 32542

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLLIAEHDHAQLKDATNKALTAAAALGAEVHVLVAGGGEGTKAAAEAAAKLQGVAKVL
CCEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHH
LADAPLYEHDLAEPLAALIVSLAPNYDAIVAPATSRFKNVMPRVAALLDVMQVSEIIKVI
HHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APDTYERPIYAGNAIQTVKSKDAKKVITVRTSTFQATGEGGSAAIEPVAAAADPGLSTFV
CCCCCCCCEECCCHHHHHHCCCCCEEEEEEECEEEECCCCCCCHHCCHHHHCCCCHHHHH
GEEVAKSDRPELASAKIIVSGGRAMQSRENFTKYIEPLADKLGAGVGASRAAVDAGYAPN
HHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCC
DWQVGQTGKVVAPELYIAIGISGAIQHLAGMKDSKVIVAINKDEDAPIFQVADYGLVADL
CCCCCCCCCEECCEEEEEEECHHHHHHHHCCCCCEEEEEEECCCCCCEEEEHHHHHHHHH
YQAVPELTDELGKLGK
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATLLIAEHDHAQLKDATNKALTAAAALGAEVHVLVAGGGEGTKAAAEAAAKLQGVAKVL
CEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHH
LADAPLYEHDLAEPLAALIVSLAPNYDAIVAPATSRFKNVMPRVAALLDVMQVSEIIKVI
HHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APDTYERPIYAGNAIQTVKSKDAKKVITVRTSTFQATGEGGSAAIEPVAAAADPGLSTFV
CCCCCCCCEECCCHHHHHHCCCCCEEEEEEECEEEECCCCCCCHHCCHHHHCCCCHHHHH
GEEVAKSDRPELASAKIIVSGGRAMQSRENFTKYIEPLADKLGAGVGASRAAVDAGYAPN
HHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCC
DWQVGQTGKVVAPELYIAIGISGAIQHLAGMKDSKVIVAINKDEDAPIFQVADYGLVADL
CCCCCCCCCEECCEEEEEEECHHHHHHHHCCCCCEEEEEEECCCCCCEEEEHHHHHHHHH
YQAVPELTDELGKLGK
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]