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The map label for this gene is sdhB [H]

Identifier: 86747450

GI number: 86747450

Start: 368777

End: 369586

Strand: Reverse

Name: sdhB [H]

Synonym: RPB_0324

Alternate gene names: 86747450

Gene position: 369586-368777 (Counterclockwise)

Preceding gene: 86747451

Following gene: 86747449

Centisome position: 6.93

GC content: 63.46

Gene sequence:

>810_bases
ATGACGAACAGAGCCAGAGGCAACGAGATGGTTGAATTCGCACTTCCGAAGAATTCGAAGATTGTCGGCGGCAAGGCCTG
GCCGAAGCCGGAAGGCGCGACGGAAGTTCGCGAATTCCGCGTCTATCGCTGGAATCCCGACGACGGCAAGAACCCGAGCG
TCGACACCTACTACGTCGACAAGCACGATTGCGGCCCGATGGTGCTCGACGGCCTGATCTGGATCAAGAACAACATCGAT
CCGACGCTGACCTTCCGCCGCTCCTGCCGCGAAGGCGTGTGCGGCTCCTGCGCGATGAACATCGACGGCGAGAACACGCT
GGCCTGCACCAAGGCGATGGACGACGTCCGCGGCGAGGCGGTGAAGGTCAACCCGCTGCCGCACCAGCCGGTGGTCAAGG
ACCTGGTCCCCGACCTCACCAATTTCTACGCGCAATACGCCTCGATCGAACCGTGGCTGCAAACGGTGACGCCGACGCCG
CAGAAGGAATGGCGGCAGAGCCACGCCGATCGCGAGAAGCTCGACGGCCTGTACGAGTGCATCCTGTGCGCCTGCTGCTC
GACCTCGTGCCCGAGCTATTGGTGGAATTCCGACCGCTTCCTCGGACCGGCCGCGCTGCTGCAGGCGACCCGCTGGGTCG
AGGATTCGCGCGACGAAGCCACCGGCGAGCGGCTCGACAATCTCGAGGATCCGTTCCGGATCTATCGCTGCCACACCATC
ATGAACTGCGCCAAGGCGTGCCCGAAGGGCCTCAACCCGTCGGAAGCGATCGCCAGCCTCAAGCTCAAGCTGGTCGAACG
CCAGATCTGA

Upstream 100 bases:

>100_bases
CGAAGCCGCGGGTGTATTGATCCAAGATCGTCATGCCCGGGCTTGACCCGGGCATCCATCGCTCTTCGCAAGAAGATGGA
TTGCCGGGTCAAGCCCGGCA

Downstream 100 bases:

>100_bases
GGGCGCCGATCGTTTGCTGCGTTGCAATGGCCGGGCCTCGTCCCGGCCATTTGCTTGTCTGCGCCCGCCCGACACCATCG
CCATCGCCATTGCGGAACAT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTNRARGNEMVEFALPKNSKIVGGKAWPKPEGATEVREFRVYRWNPDDGKNPSVDTYYVDKHDCGPMVLDGLIWIKNNID
PTLTFRRSCREGVCGSCAMNIDGENTLACTKAMDDVRGEAVKVNPLPHQPVVKDLVPDLTNFYAQYASIEPWLQTVTPTP
QKEWRQSHADREKLDGLYECILCACCSTSCPSYWWNSDRFLGPAALLQATRWVEDSRDEATGERLDNLEDPFRIYRCHTI
MNCAKACPKGLNPSEAIASLKLKLVERQI

Sequences:

>Translated_269_residues
MTNRARGNEMVEFALPKNSKIVGGKAWPKPEGATEVREFRVYRWNPDDGKNPSVDTYYVDKHDCGPMVLDGLIWIKNNID
PTLTFRRSCREGVCGSCAMNIDGENTLACTKAMDDVRGEAVKVNPLPHQPVVKDLVPDLTNFYAQYASIEPWLQTVTPTP
QKEWRQSHADREKLDGLYECILCACCSTSCPSYWWNSDRFLGPAALLQATRWVEDSRDEATGERLDNLEDPFRIYRCHTI
MNCAKACPKGLNPSEAIASLKLKLVERQI
>Mature_268_residues
TNRARGNEMVEFALPKNSKIVGGKAWPKPEGATEVREFRVYRWNPDDGKNPSVDTYYVDKHDCGPMVLDGLIWIKNNIDP
TLTFRRSCREGVCGSCAMNIDGENTLACTKAMDDVRGEAVKVNPLPHQPVVKDLVPDLTNFYAQYASIEPWLQTVTPTPQ
KEWRQSHADREKLDGLYECILCACCSTSCPSYWWNSDRFLGPAALLQATRWVEDSRDEATGERLDNLEDPFRIYRCHTIM
NCAKACPKGLNPSEAIASLKLKLVERQI

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=232, Percent_Identity=63.3620689655172, Blast_Score=321, Evalue=4e-88,
Organism=Escherichia coli, GI1786943, Length=234, Percent_Identity=51.7094017094017, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI1790596, Length=227, Percent_Identity=33.4801762114537, Blast_Score=134, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17533915, Length=229, Percent_Identity=60.6986899563319, Blast_Score=306, Evalue=5e-84,
Organism=Saccharomyces cerevisiae, GI6322987, Length=231, Percent_Identity=61.4718614718615, Blast_Score=301, Evalue=8e-83,
Organism=Drosophila melanogaster, GI17137106, Length=253, Percent_Identity=59.2885375494071, Blast_Score=328, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24643156, Length=234, Percent_Identity=60.2564102564103, Blast_Score=300, Evalue=8e-82,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 30432; Mature: 30301

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRARGNEMVEFALPKNSKIVGGKAWPKPEGATEVREFRVYRWNPDDGKNPSVDTYYVD
CCCCCCCCCEEEEECCCCCEEECCCCCCCCCCHHHHHHEEEEEECCCCCCCCCCCEEECC
KHDCGPMVLDGLIWIKNNIDPTLTFRRSCREGVCGSCAMNIDGENTLACTKAMDDVRGEA
CCCCCHHHHHCEEEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHCCCE
VKVNPLPHQPVVKDLVPDLTNFYAQYASIEPWLQTVTPTPQKEWRQSHADREKLDGLYEC
EEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHCCHHHHHHHHHH
ILCACCSTSCPSYWWNSDRFLGPAALLQATRWVEDSRDEATGERLDNLEDPFRIYRCHTI
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHH
MNCAKACPKGLNPSEAIASLKLKLVERQI
HHHHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNRARGNEMVEFALPKNSKIVGGKAWPKPEGATEVREFRVYRWNPDDGKNPSVDTYYVD
CCCCCCCCEEEEECCCCCEEECCCCCCCCCCHHHHHHEEEEEECCCCCCCCCCCEEECC
KHDCGPMVLDGLIWIKNNIDPTLTFRRSCREGVCGSCAMNIDGENTLACTKAMDDVRGEA
CCCCCHHHHHCEEEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHCCCE
VKVNPLPHQPVVKDLVPDLTNFYAQYASIEPWLQTVTPTPQKEWRQSHADREKLDGLYEC
EEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHCCHHHHHHHHHH
ILCACCSTSCPSYWWNSDRFLGPAALLQATRWVEDSRDEATGERLDNLEDPFRIYRCHTI
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHH
MNCAKACPKGLNPSEAIASLKLKLVERQI
HHHHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA