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The map label for this gene is rppH [H]

Identifier: 86747389

GI number: 86747389

Start: 296719

End: 297213

Strand: Direct

Name: rppH [H]

Synonym: RPB_0263

Alternate gene names: 86747389

Gene position: 296719-297213 (Clockwise)

Preceding gene: 86747388

Following gene: 86747395

Centisome position: 5.57

GC content: 66.06

Gene sequence:

>495_bases
ATGCCGTACCGGCGCAATGTCGGAATCGCGCTGTTCAACGCCGAAGGCCGGGTGCTGATCGGCCGCCGCTTCCGCGACGA
CGGCCCGGAGATCATCCTGCCCGGCCTCGAATGGCAGATGCCGCAAGGCGGCATCGACGAAGGCGAGGAGCCGCACACCG
CGGTGATGCGCGAATTGTGGGAGGAGACCGGCGTGCAGCACGCCGAGCTGCTCGGCGAAGCCGATTGGATCGCTTACGAC
TTCCCGCCCTATGACGGCCCGCCGCATCGGCTCGAGCATTTTCGCGGCCAACGGCAAAAATGGTTCGCGCTGCGCTTCAC
CGGCAATGACAGCGAGATCGATCCGCTCGCGGTGCGCAACGACATGCCACCTGAATTCGACGCCTGGCGCTGGGAGCGGC
TCGATCGCGTCGCCGACCTGGTGGTGCCGTTCAGGCGCGAGGTCTATCGCGAAGTCGCAAGGAGCTTCGCGCGGTTCGTG
TTGCCCGCGACTTAA

Upstream 100 bases:

>100_bases
GCTGGGAGCCGAAGGTCGCACTCGCCGACGGGCTGAAGGAGACCATCTCCTACTTCCGCAAGCTGCTGGCGTCGTGAGCG
ACCGGCCGGCGGTCGACTCG

Downstream 100 bases:

>100_bases
CCGCAGCGCTCCTTCGCAAAGAACCGTCATGCGCGGGCTTGACCCGCGCATCCATCGCTCTTCGGAAAGGAGATGGATGC
CGGGTCAAGCCCGGCAATGA

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MPYRRNVGIALFNAEGRVLIGRRFRDDGPEIILPGLEWQMPQGGIDEGEEPHTAVMRELWEETGVQHAELLGEADWIAYD
FPPYDGPPHRLEHFRGQRQKWFALRFTGNDSEIDPLAVRNDMPPEFDAWRWERLDRVADLVVPFRREVYREVARSFARFV
LPAT

Sequences:

>Translated_164_residues
MPYRRNVGIALFNAEGRVLIGRRFRDDGPEIILPGLEWQMPQGGIDEGEEPHTAVMRELWEETGVQHAELLGEADWIAYD
FPPYDGPPHRLEHFRGQRQKWFALRFTGNDSEIDPLAVRNDMPPEFDAWRWERLDRVADLVVPFRREVYREVARSFARFV
LPAT
>Mature_163_residues
PYRRNVGIALFNAEGRVLIGRRFRDDGPEIILPGLEWQMPQGGIDEGEEPHTAVMRELWEETGVQHAELLGEADWIAYDF
PPYDGPPHRLEHFRGQRQKWFALRFTGNDSEIDPLAVRNDMPPEFDAWRWERLDRVADLVVPFRREVYREVARSFARFVL
PAT

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=166, Percent_Identity=37.3493975903614, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 19216; Mature: 19085

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYRRNVGIALFNAEGRVLIGRRFRDDGPEIILPGLEWQMPQGGIDEGEEPHTAVMRELW
CCCCCCCCEEEECCCCCEEEECCCCCCCCEEEECCCCEECCCCCCCCCCCHHHHHHHHHH
EETGVQHAELLGEADWIAYDFPPYDGPPHRLEHFRGQRQKWFALRFTGNDSEIDPLAVRN
HHHCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCEEECC
DMPPEFDAWRWERLDRVADLVVPFRREVYREVARSFARFVLPAT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PYRRNVGIALFNAEGRVLIGRRFRDDGPEIILPGLEWQMPQGGIDEGEEPHTAVMRELW
CCCCCCCEEEECCCCCEEEECCCCCCCCEEEECCCCEECCCCCCCCCCCHHHHHHHHHH
EETGVQHAELLGEADWIAYDFPPYDGPPHRLEHFRGQRQKWFALRFTGNDSEIDPLAVRN
HHHCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCEEECC
DMPPEFDAWRWERLDRVADLVVPFRREVYREVARSFARFVLPAT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA