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The map label for this gene is yjeP [H]

Identifier: 86747184

GI number: 86747184

Start: 59695

End: 61008

Strand: Direct

Name: yjeP [H]

Synonym: RPB_0057

Alternate gene names: 86747184

Gene position: 59695-61008 (Clockwise)

Preceding gene: 86747178

Following gene: 86747185

Centisome position: 1.12

GC content: 65.53

Gene sequence:

>1314_bases
ATGATCGATTTCACCCAGGCCTCCGAGGCGCTGCTGTCGGCTGCGCGTTCGGTCGGCGCTGAATTCACCGCGCCCTGGTT
CTATGCCCAGCTCGGCATCATCATCACCGCGCTCGGGGTCGGGCTCGGCGGCGGCGCGCTGATCAAGGCGCGGGTCGACC
TGACCACGCTGACGATGGGCTGGCCGGTACCGTTGCGGACGTTCCTGCGGGTGGTGGTCGACAGCGCCTGGACCGCGCTC
TTCGCGCTGACCCTGATCCTGGCGCGCGTGGTGATGTTGCACGCGACCTGGCCGAGCCGCAGCTATCTGATCGGCATCGC
CGCCAAGCTGGCGCTGGCCTGGCTTCTGATCCGGCTGGTCACCAGCATCCTGCGCAACGCCTTCCTGATCCGGGTGGTGT
CGGTCTCGGCCTGGTGCGTGGCGGCGCTCAGCATCATCGGGCAATTGTTTCCGGTGCTGGAGGCGCTGGATTCGGTCGCG
ATCGTGGTCGGCGATCTGCGGCTGTCGCCGCTGCTGGTGATCAAACTCTGCGTGCTGCTGGCGATCGCGCTGTGGCTCGC
CAATATCGCCAGCAATTTCTTCGAGGGCCGGATCAACCGGACCGCGGACCTGACGCCGTCGGTGCAGGTGCTGCTGATCA
AGCTGATGCGGATCGGCCTGATGGTGTTCGCGATCGCGCTGACGATGAGCGCGGTCGGCATCAATCTGCAGGCGCTGGCG
GTGTTCTCCGGCGCGGTCGGCGTCGGCATCGGTTTCGGGTTGCAGAAGATCTTCGGCAATTTCATCTCGGGCGTGATCCT
GCTCGCCGACAAATCGGTCAAGCCCGGCGATCTCGTCACCATCGGCGACAGTTCCGGCAAGATCAGCGCGATGAACACGC
GCTATATTTCGGTGGCGGCCGGCGACGGCCGTGAATTCCTGATCCCGAACGAGGATTTGATCACCCAGAAGGTGGTCAAC
TGGACCTACACCGACAGGAACACGCTGGTGAAGGTCGCCTTCGCCACCAATTACGACGCCGATCCCCGCCTCGTCTGCCA
GCTCGCGATCGACGTCGCGACGAACGTGGCGCGGGCGTCGAAGGCCAAGCCGCCGGGCTGCATCCTCACCGAATTCACCG
ATACGGGGATGAAATTCGCCCTGACCTTCTGGATCGCCGAGCCGGACGGCATGGACGCGGTCAAAAGCGAGGCGATGCTC
GGGCTGTGGGACGCGTTCAAGCGCGAGGGCATCCGGGTGCCCTATCCGGTGCGCGAGATCCGCGTCCGCGGCGGCGCGCT
GCCGGTCGAGACTATCGTCGAGGTGCCGCGTTGA

Upstream 100 bases:

>100_bases
AGGGGGCTCGGGTGAGGGCGCGCCGGGCACCGGGCCGCTGGCCGAAATCCCGGCCGCCCGTTAAGAGAGAGTCGCAATCC
ATGGAAACGCGGCACCGGCG

Downstream 100 bases:

>100_bases
GCCGTTCCGGCGCGCCCGCTGGGGCTTTTGCTTGCGCCCACCGCTGCGATGACTAAATTGGCCTCACATCCTCCGTTTTC
CTCAACCAGACCGGCCCGAT

Product: MscS mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MIDFTQASEALLSAARSVGAEFTAPWFYAQLGIIITALGVGLGGGALIKARVDLTTLTMGWPVPLRTFLRVVVDSAWTAL
FALTLILARVVMLHATWPSRSYLIGIAAKLALAWLLIRLVTSILRNAFLIRVVSVSAWCVAALSIIGQLFPVLEALDSVA
IVVGDLRLSPLLVIKLCVLLAIALWLANIASNFFEGRINRTADLTPSVQVLLIKLMRIGLMVFAIALTMSAVGINLQALA
VFSGAVGVGIGFGLQKIFGNFISGVILLADKSVKPGDLVTIGDSSGKISAMNTRYISVAAGDGREFLIPNEDLITQKVVN
WTYTDRNTLVKVAFATNYDADPRLVCQLAIDVATNVARASKAKPPGCILTEFTDTGMKFALTFWIAEPDGMDAVKSEAML
GLWDAFKREGIRVPYPVREIRVRGGALPVETIVEVPR

Sequences:

>Translated_437_residues
MIDFTQASEALLSAARSVGAEFTAPWFYAQLGIIITALGVGLGGGALIKARVDLTTLTMGWPVPLRTFLRVVVDSAWTAL
FALTLILARVVMLHATWPSRSYLIGIAAKLALAWLLIRLVTSILRNAFLIRVVSVSAWCVAALSIIGQLFPVLEALDSVA
IVVGDLRLSPLLVIKLCVLLAIALWLANIASNFFEGRINRTADLTPSVQVLLIKLMRIGLMVFAIALTMSAVGINLQALA
VFSGAVGVGIGFGLQKIFGNFISGVILLADKSVKPGDLVTIGDSSGKISAMNTRYISVAAGDGREFLIPNEDLITQKVVN
WTYTDRNTLVKVAFATNYDADPRLVCQLAIDVATNVARASKAKPPGCILTEFTDTGMKFALTFWIAEPDGMDAVKSEAML
GLWDAFKREGIRVPYPVREIRVRGGALPVETIVEVPR
>Mature_437_residues
MIDFTQASEALLSAARSVGAEFTAPWFYAQLGIIITALGVGLGGGALIKARVDLTTLTMGWPVPLRTFLRVVVDSAWTAL
FALTLILARVVMLHATWPSRSYLIGIAAKLALAWLLIRLVTSILRNAFLIRVVSVSAWCVAALSIIGQLFPVLEALDSVA
IVVGDLRLSPLLVIKLCVLLAIALWLANIASNFFEGRINRTADLTPSVQVLLIKLMRIGLMVFAIALTMSAVGINLQALA
VFSGAVGVGIGFGLQKIFGNFISGVILLADKSVKPGDLVTIGDSSGKISAMNTRYISVAAGDGREFLIPNEDLITQKVVN
WTYTDRNTLVKVAFATNYDADPRLVCQLAIDVATNVARASKAKPPGCILTEFTDTGMKFALTFWIAEPDGMDAVKSEAML
GLWDAFKREGIRVPYPVREIRVRGGALPVETIVEVPR

Specific function: Unknown

COG id: COG3264

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI2367355, Length=315, Percent_Identity=29.2063492063492, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786670, Length=157, Percent_Identity=33.1210191082803, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789291, Length=228, Percent_Identity=23.6842105263158, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 46998; Mature: 46998

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFTQASEALLSAARSVGAEFTAPWFYAQLGIIITALGVGLGGGALIKARVDLTTLTMG
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEC
WPVPLRTFLRVVVDSAWTALFALTLILARVVMLHATWPSRSYLIGIAAKLALAWLLIRLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
TSILRNAFLIRVVSVSAWCVAALSIIGQLFPVLEALDSVAIVVGDLRLSPLLVIKLCVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHH
AIALWLANIASNFFEGRINRTADLTPSVQVLLIKLMRIGLMVFAIALTMSAVGINLQALA
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VFSGAVGVGIGFGLQKIFGNFISGVILLADKSVKPGDLVTIGDSSGKISAMNTRYISVAA
HHHCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEECCCCCEEEEEEEEEEEEEE
GDGREFLIPNEDLITQKVVNWTYTDRNTLVKVAFATNYDADPRLVCQLAIDVATNVARAS
CCCCEEECCCHHHHHHHHHCCEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
KAKPPGCILTEFTDTGMKFALTFWIAEPDGMDAVKSEAMLGLWDAFKREGIRVPYPVREI
CCCCCCEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
RVRGGALPVETIVEVPR
EECCCCCCHHHHHCCCC
>Mature Secondary Structure
MIDFTQASEALLSAARSVGAEFTAPWFYAQLGIIITALGVGLGGGALIKARVDLTTLTMG
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEC
WPVPLRTFLRVVVDSAWTALFALTLILARVVMLHATWPSRSYLIGIAAKLALAWLLIRLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
TSILRNAFLIRVVSVSAWCVAALSIIGQLFPVLEALDSVAIVVGDLRLSPLLVIKLCVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHH
AIALWLANIASNFFEGRINRTADLTPSVQVLLIKLMRIGLMVFAIALTMSAVGINLQALA
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VFSGAVGVGIGFGLQKIFGNFISGVILLADKSVKPGDLVTIGDSSGKISAMNTRYISVAA
HHHCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEECCCCCEEEEEEEEEEEEEE
GDGREFLIPNEDLITQKVVNWTYTDRNTLVKVAFATNYDADPRLVCQLAIDVATNVARAS
CCCCEEECCCHHHHHHHHHCCEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
KAKPPGCILTEFTDTGMKFALTFWIAEPDGMDAVKSEAMLGLWDAFKREGIRVPYPVREI
CCCCCCEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
RVRGGALPVETIVEVPR
EECCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 3042771 [H]