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The map label for this gene is hypB [H]

Identifier: 90296806

GI number: 90296806

Start: 2939367

End: 2939987

Strand: Direct

Name: hypB [H]

Synonym: CYB_2844

Alternate gene names: 90296806

Gene position: 2939367-2939987 (Clockwise)

Preceding gene: 90296805

Following gene: 86610266

Centisome position: 96.48

GC content: 58.29

Gene sequence:

>621_bases
GTGTTCAGCGTAAATGTATCAGTAACCTGTCTGAACCTCATGAGCGCGCCGGGGGCGGGTAAGACGTCTTTGCTGGAGAA
AACCGTGGTCGCTCTTGCCGGCTCGCTGCGCCTGGCGGTGATCGAGGGAGACATGACGACCCAACTGGACGCGGAGCGGT
TGCGTCGCTACGGGATCCCGGTGATTGCCATCAACACGGGGCGGGCCTGTCATTTGGATGCGGCCATGGTGGCCGGGGGC
TTGCAGCAATTGGAAGCACTGCTGGATCCCCAACAACTGGATTTGCTGCTGGTGGAAAATGTCGGCAACTTGGTCTGCCC
GGCGGAGTTTGAGGTGGGGGAACACGCCAAGGTAGCACTACTCAGCGTCACAGAAGGGGAAGACAAGCCTCTCAAGTACC
CAATCATGTTTCGAGAGGCGGATTGTCTGCTGATCACCAAAGTGGATCTGGTTCCTGTGTTGGAGGTGGATTTGGATCGG
ATCCAGGCCAATATCCGCGAGATCAACCCTTCTGTGCCGATTTTTTGTCTTTCTGCCAAGACGGGTGACGGGCTGGAGCC
CTGGCTGGGCTGGATCCGAGAGCAGATTCTCCTTGCCCAACACCGACGGCAGCCGCAGTGA

Upstream 100 bases:

>100_bases
GCGCTTTGGGTATTCTACTCAAAGCTTTGCGGGATACCGCCATTCTGTTTGGAAACAAACAGAATGCTATCGCTGCATAG
TTGAACAGTGATGTTCAGCA

Downstream 100 bases:

>100_bases
AGGGTATCATACTGAGCATCTAGCCGTGGAACTCTCCTCACCTGAGCTGGCCAGGCAGGGGATGAGTTAGCACCTCTGGC
GGGTCAATTTGCAGATAACT

Product: hydrogenase accessory protein HypB, interruption-C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MFSVNVSVTCLNLMSAPGAGKTSLLEKTVVALAGSLRLAVIEGDMTTQLDAERLRRYGIPVIAINTGRACHLDAAMVAGG
LQQLEALLDPQQLDLLLVENVGNLVCPAEFEVGEHAKVALLSVTEGEDKPLKYPIMFREADCLLITKVDLVPVLEVDLDR
IQANIREINPSVPIFCLSAKTGDGLEPWLGWIREQILLAQHRRQPQ

Sequences:

>Translated_206_residues
MFSVNVSVTCLNLMSAPGAGKTSLLEKTVVALAGSLRLAVIEGDMTTQLDAERLRRYGIPVIAINTGRACHLDAAMVAGG
LQQLEALLDPQQLDLLLVENVGNLVCPAEFEVGEHAKVALLSVTEGEDKPLKYPIMFREADCLLITKVDLVPVLEVDLDR
IQANIREINPSVPIFCLSAKTGDGLEPWLGWIREQILLAQHRRQPQ
>Mature_206_residues
MFSVNVSVTCLNLMSAPGAGKTSLLEKTVVALAGSLRLAVIEGDMTTQLDAERLRRYGIPVIAINTGRACHLDAAMVAGG
LQQLEALLDPQQLDLLLVENVGNLVCPAEFEVGEHAKVALLSVTEGEDKPLKYPIMFREADCLLITKVDLVPVLEVDLDR
IQANIREINPSVPIFCLSAKTGDGLEPWLGWIREQILLAQHRRQPQ

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=185, Percent_Identity=52.4324324324324, Blast_Score=193, Evalue=9e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 22474; Mature: 22474

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSVNVSVTCLNLMSAPGAGKTSLLEKTVVALAGSLRLAVIEGDMTTQLDAERLRRYGIP
CEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHCCCC
VIAINTGRACHLDAAMVAGGLQQLEALLDPQQLDLLLVENVGNLVCPAEFEVGEHAKVAL
EEEEECCCEEEHHHHHHHCCHHHHHHHCCHHHHCEEEECCCCCEECCCCCCCCCCCEEEE
LSVTEGEDKPLKYPIMFREADCLLITKVDLVPVLEVDLDRIQANIREINPSVPIFCLSAK
EEEECCCCCCEEEEEEEECCCEEEEEEECCEEEHHHHHHHHHHHHHHCCCCCCEEEEECC
TGDGLEPWLGWIREQILLAQHRRQPQ
CCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFSVNVSVTCLNLMSAPGAGKTSLLEKTVVALAGSLRLAVIEGDMTTQLDAERLRRYGIP
CEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHCCCC
VIAINTGRACHLDAAMVAGGLQQLEALLDPQQLDLLLVENVGNLVCPAEFEVGEHAKVAL
EEEEECCCEEEHHHHHHHCCHHHHHHHCCHHHHCEEEECCCCCEECCCCCCCCCCCEEEE
LSVTEGEDKPLKYPIMFREADCLLITKVDLVPVLEVDLDRIQANIREINPSVPIFCLSAK
EEEECCCCCCEEEEEEEECCCEEEEEEECCEEEHHHHHHHHHHHHHHCCCCCCEEEEECC
TGDGLEPWLGWIREQILLAQHRRQPQ
CCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]