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The map label for this gene is prk [H]

Identifier: 86610304

GI number: 86610304

Start: 2983697

End: 2984704

Strand: Direct

Name: prk [H]

Synonym: CYB_2883

Alternate gene names: 86610304

Gene position: 2983697-2984704 (Clockwise)

Preceding gene: 86610300

Following gene: 86610305

Centisome position: 97.93

GC content: 57.24

Gene sequence:

>1008_bases
ATGGCAAGCAGTCCTGATCGTGTTGTGATGATTGGTGTCGCCGGAGATTCTGGCTGTGGCAAGTCCACCTTTTTACGCCG
GCTGGGGGATCTATTTGGCCGGGATCTGATTACCACCATCTGTCTGGATGACTATCACTCCTTGGATCGCTACCAGCGCA
AAGAGAAGGGCATCACGGCGCTGGATCCCCGCGCCAACAACTTCGACCTGATGTACGAGCAGGCCAAGGCGCTCAAGAAC
GGCCAAAGCGTGATGAAGCCCATCTACAACCACGAGACGGGGATGATTGACCCGCCGGAGCTGGTGGAGCCCAACCGCAT
CATCGTCCTAGAGGGGCTGCATCCCATGTATGACGAGCGGGTGCGCGAGCTGCTGGACTTTAAGGTGTACTTGGATCTGG
CGCCGGAGATCAAGATTGCTTGGAAGGTGAAGCGGGACATGGCCGAGCGGGGCCACACCTACGAAGATGTGTTGCGCTCA
ATCGAGGCTCGCCGCCCGGACTTTGAAGCCTATGTCGATGTGCAGAAGCAGTACGCCGATGCCGTCATTGAGGTTTTGCC
TACCCAGTTGTTGCCGGAGCTGGATCCAGAGCACAAAGTACTGCGGGTGCGGCTGATCCAGCGGGAAGGGGTGAAGTACT
TCGACCATGTCTATCTCTTTGACGAAGGCTCCACCATTGATTGGATCCCCTGCGGCAAAAAGCTGACTTGTTCCTATCCA
GGGATCCGCCTCCACTATGGCCCTTCCACCTACTTCGAGCACCCGGTTTCGATTCTGGAGATCGACGGCACCTTCGACAA
GCTGGAAGAGGTCATCTACATCGAGAACCACCTGAGCAACTTGTCCACCCGCTACTATGGCGAGCTGACGGAACTGTTGC
GCAAGCACCCGGAATACCCGGGATCCCGCAATGGCTCTGGTCTGATTCAGATCATCGTGGGCCTGAAGCTGCGCGCCCTC
TACGAGCAAATTCGGGCAGAAGCCAAAGAGCTGGCGGTGGCTTCCTAG

Upstream 100 bases:

>100_bases
GATGTAACGGCTTTATTTGGTATCATGCAAGGCCGTAACAGTTGGTAACTTTCTAGAGCCTTTTTCTCAGTTTTGCCCTG
CCCGTCCCCAAGGAGTTCCC

Downstream 100 bases:

>100_bases
TGTTTGCCCCGCTTAGGGGATCCCTTCGGTAAAGTGTTGGTGCAGGTCGGCTGACCCAGCATAGGTCGGCAGTAGGGCTT
CGGTGTATGCAGGGATTCCA

Product: phosphoribulokinase

Products: NA

Alternate protein names: PRK; PRKase; Phosphopentokinase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MASSPDRVVMIGVAGDSGCGKSTFLRRLGDLFGRDLITTICLDDYHSLDRYQRKEKGITALDPRANNFDLMYEQAKALKN
GQSVMKPIYNHETGMIDPPELVEPNRIIVLEGLHPMYDERVRELLDFKVYLDLAPEIKIAWKVKRDMAERGHTYEDVLRS
IEARRPDFEAYVDVQKQYADAVIEVLPTQLLPELDPEHKVLRVRLIQREGVKYFDHVYLFDEGSTIDWIPCGKKLTCSYP
GIRLHYGPSTYFEHPVSILEIDGTFDKLEEVIYIENHLSNLSTRYYGELTELLRKHPEYPGSRNGSGLIQIIVGLKLRAL
YEQIRAEAKELAVAS

Sequences:

>Translated_335_residues
MASSPDRVVMIGVAGDSGCGKSTFLRRLGDLFGRDLITTICLDDYHSLDRYQRKEKGITALDPRANNFDLMYEQAKALKN
GQSVMKPIYNHETGMIDPPELVEPNRIIVLEGLHPMYDERVRELLDFKVYLDLAPEIKIAWKVKRDMAERGHTYEDVLRS
IEARRPDFEAYVDVQKQYADAVIEVLPTQLLPELDPEHKVLRVRLIQREGVKYFDHVYLFDEGSTIDWIPCGKKLTCSYP
GIRLHYGPSTYFEHPVSILEIDGTFDKLEEVIYIENHLSNLSTRYYGELTELLRKHPEYPGSRNGSGLIQIIVGLKLRAL
YEQIRAEAKELAVAS
>Mature_334_residues
ASSPDRVVMIGVAGDSGCGKSTFLRRLGDLFGRDLITTICLDDYHSLDRYQRKEKGITALDPRANNFDLMYEQAKALKNG
QSVMKPIYNHETGMIDPPELVEPNRIIVLEGLHPMYDERVRELLDFKVYLDLAPEIKIAWKVKRDMAERGHTYEDVLRSI
EARRPDFEAYVDVQKQYADAVIEVLPTQLLPELDPEHKVLRVRLIQREGVKYFDHVYLFDEGSTIDWIPCGKKLTCSYPG
IRLHYGPSTYFEHPVSILEIDGTFDKLEEVIYIENHLSNLSTRYYGELTELLRKHPEYPGSRNGSGLIQIIVGLKLRALY
EQIRAEAKELAVAS

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoribulokinase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=180, Percent_Identity=29.4444444444444, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI57863312, Length=180, Percent_Identity=29.4444444444444, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI18699734, Length=187, Percent_Identity=25.1336898395722, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI13899253, Length=190, Percent_Identity=25.2631578947368, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082034, Length=191, Percent_Identity=31.9371727748691, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17539892, Length=180, Percent_Identity=27.2222222222222, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17539894, Length=180, Percent_Identity=27.2222222222222, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71981181, Length=190, Percent_Identity=30, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324339, Length=125, Percent_Identity=28.8, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221458995, Length=199, Percent_Identity=27.6381909547739, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24649624, Length=188, Percent_Identity=27.6595744680851, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550449, Length=180, Percent_Identity=25.5555555555556, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28573516, Length=180, Percent_Identity=25.5555555555556, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28573514, Length=180, Percent_Identity=25.5555555555556, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28573512, Length=180, Percent_Identity=25.5555555555556, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006082
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.19 [H]

Molecular weight: Translated: 38462; Mature: 38330

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00567 PHOSPHORIBULOKINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSPDRVVMIGVAGDSGCGKSTFLRRLGDLFGRDLITTICLDDYHSLDRYQRKEKGITA
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LDPRANNFDLMYEQAKALKNGQSVMKPIYNHETGMIDPPELVEPNRIIVLEGLHPMYDER
ECCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHH
VRELLDFKVYLDLAPEIKIAWKVKRDMAERGHTYEDVLRSIEARRPDFEAYVDVQKQYAD
HHHHHHHHHEEECCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
AVIEVLPTQLLPELDPEHKVLRVRLIQREGVKYFDHVYLFDEGSTIDWIPCGKKLTCSYP
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEEECCCEEEECCC
GIRLHYGPSTYFEHPVSILEIDGTFDKLEEVIYIENHLSNLSTRYYGELTELLRKHPEYP
CEEEECCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GSRNGSGLIQIIVGLKLRALYEQIRAEAKELAVAS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASSPDRVVMIGVAGDSGCGKSTFLRRLGDLFGRDLITTICLDDYHSLDRYQRKEKGITA
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LDPRANNFDLMYEQAKALKNGQSVMKPIYNHETGMIDPPELVEPNRIIVLEGLHPMYDER
ECCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHH
VRELLDFKVYLDLAPEIKIAWKVKRDMAERGHTYEDVLRSIEARRPDFEAYVDVQKQYAD
HHHHHHHHHEEECCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
AVIEVLPTQLLPELDPEHKVLRVRLIQREGVKYFDHVYLFDEGSTIDWIPCGKKLTCSYP
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEEECCCEEEECCC
GIRLHYGPSTYFEHPVSILEIDGTFDKLEEVIYIENHLSNLSTRYYGELTELLRKHPEYP
CEEEECCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GSRNGSGLIQIIVGLKLRALYEQIRAEAKELAVAS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1660882; 8905231 [H]