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The map label for this gene is pgl [H]

Identifier: 86610305

GI number: 86610305

Start: 2984791

End: 2985522

Strand: Direct

Name: pgl [H]

Synonym: CYB_2885

Alternate gene names: 86610305

Gene position: 2984791-2985522 (Clockwise)

Preceding gene: 86610304

Following gene: 86610310

Centisome position: 97.97

GC content: 61.89

Gene sequence:

>732_bases
ATGCAGGGATTCCAGTTGGAGATCTTTCCGGAGGGCCCCGTCTTAATCCAACGGGCCATCGAGATTTGGCAAGCTCGGTC
AGCCGCTGCCATTCGCGAGCGGGGACGCTTTACGGTGGCCTTGGCGGGAGGGAGCACCCCCAAGAAGCTGTATGCTGCCC
TGGCCCAAACCCCAGGGATCCCTTGGCAACAAACCTGGCTGTTCTGGGGGGATGAGCGCTATGTTCCCCCGGATCACCCT
GAAAGCAACTACCGCATGGTACGAGAAACCCTGCTGCAGCAGATCGGGATCCCGGCAGCTCAAGTTTTCCCCATGCCTAC
CCAAGCGGGGGATCCCCTTCGCGATGCTGCCGAATACGAGGCCACCCTACGGCAGATTTTCGGTGCAGAGTGCCCTTCTC
TCGACCTGGTATGGCTGGGGGTGGGGGAAGACGGCCACACAGCTTCTCTATTTCCCGACACCGCCGCTCTGCAGGTGCAG
CACCGCTGGGTGACGGTGGGGCAAAAAGGGCAGGAGCCGCGTCTAACCTTGACCTATCCTGTTCTGAACCAAGCAGCCCA
GGTGGTGTTCCTGGTAACCGGAGCGAACAAAGCCCCCATCGTGAAAGAGGCGCTGACCACCGAGGCCCACCTACCCTGCC
AGCGCGTAAACCCCAGAGGACGGCTGCTGTGGTTGCTGGATGCGGCGGCAGCAGCTCAACTGCCCCTGCCCTGTGTCCCG
CTGCTCAGCTAA

Upstream 100 bases:

>100_bases
CGGTGGCTTCCTAGTGTTTGCCCCGCTTAGGGGATCCCTTCGGTAAAGTGTTGGTGCAGGTCGGCTGACCCAGCATAGGT
CGGCAGTAGGGCTTCGGTGT

Downstream 100 bases:

>100_bases
ACAACAGGCGGGCTAACTGCCGATGGGATAGGATCCCCAGGCCCACCGCCCCCAAAATCATCCCAGCCCATTCCAGTGGC
CACAGGTTTGATAGCCCCAG

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MQGFQLEIFPEGPVLIQRAIEIWQARSAAAIRERGRFTVALAGGSTPKKLYAALAQTPGIPWQQTWLFWGDERYVPPDHP
ESNYRMVRETLLQQIGIPAAQVFPMPTQAGDPLRDAAEYEATLRQIFGAECPSLDLVWLGVGEDGHTASLFPDTAALQVQ
HRWVTVGQKGQEPRLTLTYPVLNQAAQVVFLVTGANKAPIVKEALTTEAHLPCQRVNPRGRLLWLLDAAAAAQLPLPCVP
LLS

Sequences:

>Translated_243_residues
MQGFQLEIFPEGPVLIQRAIEIWQARSAAAIRERGRFTVALAGGSTPKKLYAALAQTPGIPWQQTWLFWGDERYVPPDHP
ESNYRMVRETLLQQIGIPAAQVFPMPTQAGDPLRDAAEYEATLRQIFGAECPSLDLVWLGVGEDGHTASLFPDTAALQVQ
HRWVTVGQKGQEPRLTLTYPVLNQAAQVVFLVTGANKAPIVKEALTTEAHLPCQRVNPRGRLLWLLDAAAAAQLPLPCVP
LLS
>Mature_243_residues
MQGFQLEIFPEGPVLIQRAIEIWQARSAAAIRERGRFTVALAGGSTPKKLYAALAQTPGIPWQQTWLFWGDERYVPPDHP
ESNYRMVRETLLQQIGIPAAQVFPMPTQAGDPLRDAAEYEATLRQIFGAECPSLDLVWLGVGEDGHTASLFPDTAALQVQ
HRWVTVGQKGQEPRLTLTYPVLNQAAQVVFLVTGANKAPIVKEALTTEAHLPCQRVNPRGRLLWLLDAAAAAQLPLPCVP
LLS

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912586, Length=216, Percent_Identity=41.2037037037037, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI52145310, Length=229, Percent_Identity=36.2445414847162, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI115533058, Length=217, Percent_Identity=31.3364055299539, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI115533060, Length=217, Percent_Identity=31.3364055299539, Blast_Score=94, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6321687, Length=253, Percent_Identity=31.2252964426877, Blast_Score=102, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6319918, Length=212, Percent_Identity=33.9622641509434, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324362, Length=211, Percent_Identity=32.2274881516588, Blast_Score=96, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6321957, Length=227, Percent_Identity=29.0748898678414, Blast_Score=89, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24641119, Length=227, Percent_Identity=34.3612334801762, Blast_Score=104, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900
- InterPro:   IPR006148 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 26745; Mature: 26745

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGFQLEIFPEGPVLIQRAIEIWQARSAAAIRERGRFTVALAGGSTPKKLYAALAQTPGI
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCC
PWQQTWLFWGDERYVPPDHPESNYRMVRETLLQQIGIPAAQVFPMPTQAGDPLRDAAEYE
CCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHEECCCCCCCCCHHHHHHHH
ATLRQIFGAECPSLDLVWLGVGEDGHTASLFPDTAALQVQHRWVTVGQKGQEPRLTLTYP
HHHHHHHCCCCCCCEEEEEEECCCCCEEEECCCCEEEEEEEEEEEECCCCCCCEEEEEHH
VLNQAAQVVFLVTGANKAPIVKEALTTEAHLPCQRVNPRGRLLWLLDAAAAAQLPLPCVP
HHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHHCCCCCCEEEEEECHHHHCCCCCCCC
LLS
CCC
>Mature Secondary Structure
MQGFQLEIFPEGPVLIQRAIEIWQARSAAAIRERGRFTVALAGGSTPKKLYAALAQTPGI
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCC
PWQQTWLFWGDERYVPPDHPESNYRMVRETLLQQIGIPAAQVFPMPTQAGDPLRDAAEYE
CCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHEECCCCCCCCCHHHHHHHH
ATLRQIFGAECPSLDLVWLGVGEDGHTASLFPDTAALQVQHRWVTVGQKGQEPRLTLTYP
HHHHHHHCCCCCCCEEEEEEECCCCCEEEECCCCEEEEEEEEEEEECCCCCCCEEEEEHH
VLNQAAQVVFLVTGANKAPIVKEALTTEAHLPCQRVNPRGRLLWLLDAAAAAQLPLPCVP
HHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHHCCCCCCEEEEEECHHHHCCCCCCCC
LLS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]