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The map label for this gene is trxB [H]

Identifier: 86610230

GI number: 86610230

Start: 2904959

End: 2906389

Strand: Direct

Name: trxB [H]

Synonym: CYB_2806

Alternate gene names: 86610230

Gene position: 2904959-2906389 (Clockwise)

Preceding gene: 86610229

Following gene: 86610234

Centisome position: 95.35

GC content: 58.98

Gene sequence:

>1431_bases
ATGACAGAGCAAAGTCGGGTTGAGAATGTGGTGATTATCGGCTCCGGCCCTGCTGGGTTTACAGCAGCCATTTACGCTGG
GCGTGCCAACCTGAAGCCGGTTGTGTTTGAGGGGTTCCAGGCGGGCGGGATCCCGGGCGGGCAACTGATGACCACCACCG
AGGTGGAGAACTTTCCGGGCTTTCCCGAGGGCATCACCGGCCCCCAACTGATGAAGAACATGCGGGCTCAAGCGCAGCGG
TGGGGGGCAGAACTTTACACCGAAGATGTCACCTTTGTGGATTTAAGCCAGCGGCCCTTTGTCGTCTGTTCTGACGAGCG
GGAATTGCGCACCCACAGCCTGATCATCGCCACCGGGGCCACAGCCAAGCGCCTACACCTGCCGGGGGAGGAGACCTACT
GGAACCGGGGCATGTCAGCTTGTGCTGTCTGCGATGGGGCTATGCCCATGTTCAGAGGGGTGGAATTGGTGGTGATCGGC
GGCGGCGATACTGCCTGTGAGGAGGCCACCTACCTGACCAAGTTTGGATCCCACGTGCACATGCTGGTGCGCAGCGACAA
AATGCGGGCCAGCAAGGCCATGCAGGATCGTGTTCTCAACAACCCCAAGATCACTGTGCACTGGAACACCGAGGCGGTGG
AAGTGATGGGCGACGGCCTGCGCCTGACCGGGGTGAAAGTGCGGAACAACCAAACCGGCGAAATACGCGAGATGTCAGTG
GGTGGCCTATTTTATGCCATTGGCCACAAGCCCAACACCGACTTGTTCAAAGGACAACTGGAACTGGATGAAGTCGGCTA
CATCGTCACCCGCCCGGGATCCGTGGCCACCAGTGTGGAGGGGGTGTTTGCCGCCGGCGACGTGCAGGATCACGAGTTTC
GTCAGGCGATTACCGCTGCCGGCACTGGCTGTATGGCGGCCATGTTGGCAGAGCGTTGGCTCTCGGAACACGGCTTGGCC
CAGGAGTATCACGTCCTTCCCCAAAGCCATCCTGAACCCAGCCCTGCTGCGACTTCTGCGGCAGAGTCTGCTGGGGATCC
TGCTGTTGAGGAGGCCAGCTTTGAGGAGAATGGACAGGATGACTTAGACTTCAGCAAGACTTGCCATGAGGGGAGCTATG
CCCTGCGGCGACTCTACCACGAAAGCGATCGCCTGCTCATGGTCAAGTACACCGCCCCCACCTGTGCCCCTTGTCATGCC
CTCAAGCCGATCTTGAACAAGATCATCGATGAGTTCTCGGACAAGCTGCACGTGGTGGAGATCGATATTGAGAAAGATCC
GGAGATTGCAGAGGCAGGGGGGGTGGCGGGCACCCCGACGGTGCAATTTTTCAAAAACAAGACGCTGGTGGCCCAGTTGG
TGGGCGTTAAGCCCAAGTCCCAATATCGAGAGGTGATCCAGGCCAATTTGTGTGAGGAAAAATCCCCCTAA

Upstream 100 bases:

>100_bases
AATAGGCCTCGGCCTCGACCGGTTCGCCAAGGGGTGTTAAGCTAAAGCGTAGTCGTTATGAGTTTGGCTTTTATTCCCAT
TGCAGAAGGAGAGACATCGG

Downstream 100 bases:

>100_bases
GGATGTTGTCCTCTCCAACCTCTGGCCCCTCTCCCCAAGGGAGAAGGGAGCTGGGCGCAGAAAACGGTTTCCCAACCGAG
GCTCAGCTAGTCCGAAAAGG

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MTEQSRVENVVIIGSGPAGFTAAIYAGRANLKPVVFEGFQAGGIPGGQLMTTTEVENFPGFPEGITGPQLMKNMRAQAQR
WGAELYTEDVTFVDLSQRPFVVCSDERELRTHSLIIATGATAKRLHLPGEETYWNRGMSACAVCDGAMPMFRGVELVVIG
GGDTACEEATYLTKFGSHVHMLVRSDKMRASKAMQDRVLNNPKITVHWNTEAVEVMGDGLRLTGVKVRNNQTGEIREMSV
GGLFYAIGHKPNTDLFKGQLELDEVGYIVTRPGSVATSVEGVFAAGDVQDHEFRQAITAAGTGCMAAMLAERWLSEHGLA
QEYHVLPQSHPEPSPAATSAAESAGDPAVEEASFEENGQDDLDFSKTCHEGSYALRRLYHESDRLLMVKYTAPTCAPCHA
LKPILNKIIDEFSDKLHVVEIDIEKDPEIAEAGGVAGTPTVQFFKNKTLVAQLVGVKPKSQYREVIQANLCEEKSP

Sequences:

>Translated_476_residues
MTEQSRVENVVIIGSGPAGFTAAIYAGRANLKPVVFEGFQAGGIPGGQLMTTTEVENFPGFPEGITGPQLMKNMRAQAQR
WGAELYTEDVTFVDLSQRPFVVCSDERELRTHSLIIATGATAKRLHLPGEETYWNRGMSACAVCDGAMPMFRGVELVVIG
GGDTACEEATYLTKFGSHVHMLVRSDKMRASKAMQDRVLNNPKITVHWNTEAVEVMGDGLRLTGVKVRNNQTGEIREMSV
GGLFYAIGHKPNTDLFKGQLELDEVGYIVTRPGSVATSVEGVFAAGDVQDHEFRQAITAAGTGCMAAMLAERWLSEHGLA
QEYHVLPQSHPEPSPAATSAAESAGDPAVEEASFEENGQDDLDFSKTCHEGSYALRRLYHESDRLLMVKYTAPTCAPCHA
LKPILNKIIDEFSDKLHVVEIDIEKDPEIAEAGGVAGTPTVQFFKNKTLVAQLVGVKPKSQYREVIQANLCEEKSP
>Mature_475_residues
TEQSRVENVVIIGSGPAGFTAAIYAGRANLKPVVFEGFQAGGIPGGQLMTTTEVENFPGFPEGITGPQLMKNMRAQAQRW
GAELYTEDVTFVDLSQRPFVVCSDERELRTHSLIIATGATAKRLHLPGEETYWNRGMSACAVCDGAMPMFRGVELVVIGG
GDTACEEATYLTKFGSHVHMLVRSDKMRASKAMQDRVLNNPKITVHWNTEAVEVMGDGLRLTGVKVRNNQTGEIREMSVG
GLFYAIGHKPNTDLFKGQLELDEVGYIVTRPGSVATSVEGVFAAGDVQDHEFRQAITAAGTGCMAAMLAERWLSEHGLAQ
EYHVLPQSHPEPSPAATSAAESAGDPAVEEASFEENGQDDLDFSKTCHEGSYALRRLYHESDRLLMVKYTAPTCAPCHAL
KPILNKIIDEFSDKLHVVEIDIEKDPEIAEAGGVAGTPTVQFFKNKTLVAQLVGVKPKSQYREVIQANLCEEKSP

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=319, Percent_Identity=50.4702194357367, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI87081763, Length=319, Percent_Identity=31.0344827586207, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI87082331, Length=90, Percent_Identity=37.7777777777778, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320560, Length=312, Percent_Identity=57.3717948717949, Blast_Score=374, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6321898, Length=311, Percent_Identity=56.2700964630225, Blast_Score=365, Evalue=1e-101,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 51775; Mature: 51644

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00573 PYRIDINE_REDOX_2 ; PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQSRVENVVIIGSGPAGFTAAIYAGRANLKPVVFEGFQAGGIPGGQLMTTTEVENFPG
CCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCC
FPEGITGPQLMKNMRAQAQRWGAELYTEDVTFVDLSQRPFVVCSDERELRTHSLIIATGA
CCCCCCCHHHHHHHHHHHHHHCHHHHCCCEEEEEECCCCEEEECCCCCCCEEEEEEEECC
TAKRLHLPGEETYWNRGMSACAVCDGAMPMFRGVELVVIGGGDTACEEATYLTKFGSHVH
CEEEEECCCCHHHHHCCCCHHHHCCCCCHHHCCCEEEEECCCCCHHHHHHHHHHHCCEEE
MLVRSDKMRASKAMQDRVLNNPKITVHWNTEAVEVMGDGLRLTGVKVRNNQTGEIREMSV
EEEECCHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCEEEEEEEEECCCCCCEEEEEE
GGLFYAIGHKPNTDLFKGQLELDEVGYIVTRPGSVATSVEGVFAAGDVQDHEFRQAITAA
CEEEEEECCCCCCCCEECEEEHHHCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHC
GTGCMAAMLAERWLSEHGLAQEYHVLPQSHPEPSPAATSAAESAGDPAVEEASFEENGQD
CCHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCHHHHHHHCCCCCCHHCCCCCCCCCC
DLDFSKTCHEGSYALRRLYHESDRLLMVKYTAPTCAPCHALKPILNKIIDEFSDKLHVVE
CCCHHHHHCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEE
IDIEKDPEIAEAGGVAGTPTVQFFKNKTLVAQLVGVKPKSQYREVIQANLCEEKSP
EEECCCCCHHHCCCCCCCCCCHHHCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TEQSRVENVVIIGSGPAGFTAAIYAGRANLKPVVFEGFQAGGIPGGQLMTTTEVENFPG
CCCCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCC
FPEGITGPQLMKNMRAQAQRWGAELYTEDVTFVDLSQRPFVVCSDERELRTHSLIIATGA
CCCCCCCHHHHHHHHHHHHHHCHHHHCCCEEEEEECCCCEEEECCCCCCCEEEEEEEECC
TAKRLHLPGEETYWNRGMSACAVCDGAMPMFRGVELVVIGGGDTACEEATYLTKFGSHVH
CEEEEECCCCHHHHHCCCCHHHHCCCCCHHHCCCEEEEECCCCCHHHHHHHHHHHCCEEE
MLVRSDKMRASKAMQDRVLNNPKITVHWNTEAVEVMGDGLRLTGVKVRNNQTGEIREMSV
EEEECCHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCEEEEEEEEECCCCCCEEEEEE
GGLFYAIGHKPNTDLFKGQLELDEVGYIVTRPGSVATSVEGVFAAGDVQDHEFRQAITAA
CEEEEEECCCCCCCCEECEEEHHHCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHC
GTGCMAAMLAERWLSEHGLAQEYHVLPQSHPEPSPAATSAAESAGDPAVEEASFEENGQD
CCHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCHHHHHHHCCCCCCHHCCCCCCCCCC
DLDFSKTCHEGSYALRRLYHESDRLLMVKYTAPTCAPCHALKPILNKIIDEFSDKLHVVE
CCCHHHHHCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEE
IDIEKDPEIAEAGGVAGTPTVQFFKNKTLVAQLVGVKPKSQYREVIQANLCEEKSP
EEECCCCCHHHCCCCCCCCCCHHHCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]