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The map label for this gene is lpxA [H]

Identifier: 86610212

GI number: 86610212

Start: 2883111

End: 2884097

Strand: Direct

Name: lpxA [H]

Synonym: CYB_2787

Alternate gene names: 86610212

Gene position: 2883111-2884097 (Clockwise)

Preceding gene: 86610211

Following gene: 86610213

Centisome position: 94.63

GC content: 59.88

Gene sequence:

>987_bases
ATGAGTTCGTTCGCTTCAGCGGGATCCACTCCCAACATCTCTGCAAGTGCGCCGCACCGCTCACGGGAGCGGATTCATCC
CACTGCGGTGATCCATCCGAAAGCTGAGCTGCACGAAACGGTGCAGGTTGGCCCCTATGCGGTGATCGGCGAGCATGTTC
GCATTGCTGCCCATACGGTGGTGGGGGCCCATGTGGTGATCGATGGCTGGACGGAAATCGGCGAGGGCAACCACATTTTT
CCGGGAGCAGTTGTGGGCACCGAGCCTCAGGATCTGAAGTACAGCGGCGCCCCCTCTCAAGTGGTAATCGGCAGAGGCAA
TCGCATCCGCGAGTTCGTCACCATCAACCGGGCTACCAATGAAGGGGAAGCCACCCTGATTGGAGATTACAACCTGCTGA
TGGCCTACACCCATGTCGCCCACAACTGCGTCATCGAAAATCAGGTGGTGATTACCAATGCTGTTTCCTTGGCCGGCCAT
ATCCACATCGAGTCTCAAGCCCGCATCGGCGGCATGGTCGGGATCCACCAGTTCACCCGCATTGGGCGCTTGGCCATGGT
GGGGGCGATGAGCCGGGTTGACCGCGACGTTCCCCCCTACATGTTGGTGGAAGGACATCCGGCTCGCATCCGCGGTCTGA
ACTTGGTGGGGCTGCGGCGAGCCCAAGGGATGGAGGGATCCCTGCCCTTGCTGCGGCAGGTCTACCGATTTTTGTACCGC
TCAGGGTTGCCTTTGGAAAAAGCGCTGCAAACGCTGCGCAGCAGCCTGTGTGTCGTTTGTAACAGCGGTGCGGAGGGAGA
GCGCCATGTCCTTTCCCTACAGGGGAAAGAGTGGGTGGACGAGACGGGATCCCTGCAACATCTGCTGCAATTTTTGGAAG
ACTCCCTCTCCCAGCCCCAACGACGTGGCCCTCTGCCGGCCCTGCGCGGGAGGGGGGAAGATTCCTTATCGACAGCGATG
CAGAGCACTTCAGAGCTGGATGACTAA

Upstream 100 bases:

>100_bases
ACAGTGGGGCGTAGCTCTAAGGCTCATCTCCCCTGGAGTCAAGTCTTGGTGATCCTTCGCGGGGTTGGGAGCGTAACCAC
AGTTGCTGGCTAGGTCGGAA

Downstream 100 bases:

>100_bases
AGATTGGGGTCGGGAGCGTAGCTCTGGTGAGCCACCTGTTCATCTGCACGGGCGAGGTCTCAGGGGATCTGCAGGCCGGC
CATCTGATTGAAGAATTGCT

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSSFASAGSTPNISASAPHRSRERIHPTAVIHPKAELHETVQVGPYAVIGEHVRIAAHTVVGAHVVIDGWTEIGEGNHIF
PGAVVGTEPQDLKYSGAPSQVVIGRGNRIREFVTINRATNEGEATLIGDYNLLMAYTHVAHNCVIENQVVITNAVSLAGH
IHIESQARIGGMVGIHQFTRIGRLAMVGAMSRVDRDVPPYMLVEGHPARIRGLNLVGLRRAQGMEGSLPLLRQVYRFLYR
SGLPLEKALQTLRSSLCVVCNSGAEGERHVLSLQGKEWVDETGSLQHLLQFLEDSLSQPQRRGPLPALRGRGEDSLSTAM
QSTSELDD

Sequences:

>Translated_328_residues
MSSFASAGSTPNISASAPHRSRERIHPTAVIHPKAELHETVQVGPYAVIGEHVRIAAHTVVGAHVVIDGWTEIGEGNHIF
PGAVVGTEPQDLKYSGAPSQVVIGRGNRIREFVTINRATNEGEATLIGDYNLLMAYTHVAHNCVIENQVVITNAVSLAGH
IHIESQARIGGMVGIHQFTRIGRLAMVGAMSRVDRDVPPYMLVEGHPARIRGLNLVGLRRAQGMEGSLPLLRQVYRFLYR
SGLPLEKALQTLRSSLCVVCNSGAEGERHVLSLQGKEWVDETGSLQHLLQFLEDSLSQPQRRGPLPALRGRGEDSLSTAM
QSTSELDD
>Mature_327_residues
SSFASAGSTPNISASAPHRSRERIHPTAVIHPKAELHETVQVGPYAVIGEHVRIAAHTVVGAHVVIDGWTEIGEGNHIFP
GAVVGTEPQDLKYSGAPSQVVIGRGNRIREFVTINRATNEGEATLIGDYNLLMAYTHVAHNCVIENQVVITNAVSLAGHI
HIESQARIGGMVGIHQFTRIGRLAMVGAMSRVDRDVPPYMLVEGHPARIRGLNLVGLRRAQGMEGSLPLLRQVYRFLYRS
GLPLEKALQTLRSSLCVVCNSGAEGERHVLSLQGKEWVDETGSLQHLLQFLEDSLSQPQRRGPLPALRGRGEDSLSTAMQ
STSELDD

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=224, Percent_Identity=42.4107142857143, Blast_Score=191, Evalue=8e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 35607; Mature: 35476

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFASAGSTPNISASAPHRSRERIHPTAVIHPKAELHETVQVGPYAVIGEHVRIAAHTV
CCCCCCCCCCCCCCCCCCCCHHHCCCCEEEECCHHHHHHHHHCCCEEEECCCEEEEEHEE
VGAHVVIDGWTEIGEGNHIFPGAVVGTEPQDLKYSGAPSQVVIGRGNRIREFVTINRATN
EEEEEEEECCHHCCCCCEECCCCEECCCCCCCEECCCCCEEEEECCCCEEEEEEEECCCC
EGEATLIGDYNLLMAYTHVAHNCVIENQVVITNAVSLAGHIHIESQARIGGMVGIHQFTR
CCCEEEEECHHHHHHHHHHHHHEEECCCEEEEEHEEEEEEEEEECCCCCCCHHHHHHHHH
IGRLAMVGAMSRVDRDVPPYMLVEGHPARIRGLNLVGLRRAQGMEGSLPLLRQVYRFLYR
HHHHHHHHHHHHHCCCCCCEEEECCCCCCEECCEEEEEHHCCCCCCCCHHHHHHHHHHHH
SGLPLEKALQTLRSSLCVVCNSGAEGERHVLSLQGKEWVDETGSLQHLLQFLEDSLSQPQ
CCCCHHHHHHHHHHHHEEEECCCCCCCEEEEEECCCHHHCCCCCHHHHHHHHHHHHCCHH
RRGPLPALRGRGEDSLSTAMQSTSELDD
HHCCCCHHCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSFASAGSTPNISASAPHRSRERIHPTAVIHPKAELHETVQVGPYAVIGEHVRIAAHTV
CCCCCCCCCCCCCCCCCCCHHHCCCCEEEECCHHHHHHHHHCCCEEEECCCEEEEEHEE
VGAHVVIDGWTEIGEGNHIFPGAVVGTEPQDLKYSGAPSQVVIGRGNRIREFVTINRATN
EEEEEEEECCHHCCCCCEECCCCEECCCCCCCEECCCCCEEEEECCCCEEEEEEEECCCC
EGEATLIGDYNLLMAYTHVAHNCVIENQVVITNAVSLAGHIHIESQARIGGMVGIHQFTR
CCCEEEEECHHHHHHHHHHHHHEEECCCEEEEEHEEEEEEEEEECCCCCCCHHHHHHHHH
IGRLAMVGAMSRVDRDVPPYMLVEGHPARIRGLNLVGLRRAQGMEGSLPLLRQVYRFLYR
HHHHHHHHHHHHHCCCCCCEEEECCCCCCEECCEEEEEHHCCCCCCCCHHHHHHHHHHHH
SGLPLEKALQTLRSSLCVVCNSGAEGERHVLSLQGKEWVDETGSLQHLLQFLEDSLSQPQ
CCCCHHHHHHHHHHHHEEEECCCCCCCEEEEEECCCHHHCCCCCHHHHHHHHHHHHCCHH
RRGPLPALRGRGEDSLSTAMQSTSELDD
HHCCCCHHCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA