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The map label for this gene is cbiX [H]

Identifier: 86609787

GI number: 86609787

Start: 2454670

End: 2455713

Strand: Direct

Name: cbiX [H]

Synonym: CYB_2347

Alternate gene names: 86609787

Gene position: 2454670-2455713 (Clockwise)

Preceding gene: 86609786

Following gene: 86609788

Centisome position: 80.57

GC content: 60.82

Gene sequence:

>1044_bases
GTGTTGAATACCCTCAGTGTTTCCCCTCCGCTTGCGGTTGGGCAGTCTCCTGTTGTCCCCCTGCCCCTGTTGCTCATCGG
CCACGGATCCCGCGACCCCCAAGGGCAGCAAGCCTTTCTGGAGCTAGCCCAGGCTTACCAAGCTCTCACCCCCCATCGAC
CGGTGATCCCCTGCTTTCTGGAGCTGACCCAGCCAACCATTGCCCAGGGGGTAGAGCAGTGCTTGGCCCAAGGGTGGCAA
GAGATTGTGGTCCTGCCGCTGTTGCTGTTTGGGGCCCGCCACAACAAGTTCGATGTGACGATGGAATTGGATCTCCTGCA
GACCCTCTATCCCCAGTTGCGCATTCATTACGGTGGGCCGTTGGGGATCCGCATCGAGATCCTGCAACTGCTGCGAGACC
GATTGGCCGCTTTGATGGCCGCCCAACCGCAGCGGATCCCAGAAGCAGAAACCGTGCTCCTGTTTGTGGGTCGCGGCTCC
AGCGATCCCGAGGCCAATGCCGAAGCCTGTAAACTGGCCCGGTTGCTTTGGGAAGGATCTGGGTTTGCCGCTGTGGAAAC
TTGCTTTATCGGCATTACCCATCCCCGCCTGCCCGTGGGATTGGAGCGGGCCTTGTCCTGGCATCCGCGCCGGGTGATCG
TGCTGCCCTACTTCCTGTTTACCGGAGTGCTGGTGAAAAAAATTGAGGCGGCAGTGGAACAACAACGACAACGACAGCCG
GAAATCGACTGGCTGATGCTGCCGGAATTGGGCCTTGTGGACACGGTGCTGCACAGCCTGCAGCAACTGGAGCAGGAAGC
CCTGCAGGGCCAAACCCCGATGAACTGCCACCTGTGCAAGTTTCGCCTGGCCGTGAGCGCAGAGGTCAGAGCTGGATCCA
GCCATCACCACCCTCACGAGCCTCATGACCACCATCACGGGCATGGATCCCATCACCACCCTCATTCTCACCATCACCCT
CAGCACGGCCACACCCACGCAGCGGCTGGGGATCCCTGGGCCCAATTAGAGGGCTACCACCAACGGGCATGGCAGGTGCC
CTAA

Upstream 100 bases:

>100_bases
CGCCACTGTGACGCAACTGTGATGGGATCCCTCCCTCAGCCAGAACACCCACCTGCCGTTGTCCTGTACCCCTTGCGATT
CACAAGGAACGGAGTTTTTT

Downstream 100 bases:

>100_bases
GAGGGAAACAGAGGCTGCTGGCGGGATAAACTGAGTGCAGACAGGCAATTTTTGAACCTGGTTTTCCCGCTCTAGCGGTT
GTGATGACGAAAAAACGATG

Product: sirohydrochlorin cobaltochelatase

Products: NA

Alternate protein names: CbiXL [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MLNTLSVSPPLAVGQSPVVPLPLLLIGHGSRDPQGQQAFLELAQAYQALTPHRPVIPCFLELTQPTIAQGVEQCLAQGWQ
EIVVLPLLLFGARHNKFDVTMELDLLQTLYPQLRIHYGGPLGIRIEILQLLRDRLAALMAAQPQRIPEAETVLLFVGRGS
SDPEANAEACKLARLLWEGSGFAAVETCFIGITHPRLPVGLERALSWHPRRVIVLPYFLFTGVLVKKIEAAVEQQRQRQP
EIDWLMLPELGLVDTVLHSLQQLEQEALQGQTPMNCHLCKFRLAVSAEVRAGSSHHHPHEPHDHHHGHGSHHHPHSHHHP
QHGHTHAAAGDPWAQLEGYHQRAWQVP

Sequences:

>Translated_347_residues
MLNTLSVSPPLAVGQSPVVPLPLLLIGHGSRDPQGQQAFLELAQAYQALTPHRPVIPCFLELTQPTIAQGVEQCLAQGWQ
EIVVLPLLLFGARHNKFDVTMELDLLQTLYPQLRIHYGGPLGIRIEILQLLRDRLAALMAAQPQRIPEAETVLLFVGRGS
SDPEANAEACKLARLLWEGSGFAAVETCFIGITHPRLPVGLERALSWHPRRVIVLPYFLFTGVLVKKIEAAVEQQRQRQP
EIDWLMLPELGLVDTVLHSLQQLEQEALQGQTPMNCHLCKFRLAVSAEVRAGSSHHHPHEPHDHHHGHGSHHHPHSHHHP
QHGHTHAAAGDPWAQLEGYHQRAWQVP
>Mature_347_residues
MLNTLSVSPPLAVGQSPVVPLPLLLIGHGSRDPQGQQAFLELAQAYQALTPHRPVIPCFLELTQPTIAQGVEQCLAQGWQ
EIVVLPLLLFGARHNKFDVTMELDLLQTLYPQLRIHYGGPLGIRIEILQLLRDRLAALMAAQPQRIPEAETVLLFVGRGS
SDPEANAEACKLARLLWEGSGFAAVETCFIGITHPRLPVGLERALSWHPRRVIVLPYFLFTGVLVKKIEAAVEQQRQRQP
EIDWLMLPELGLVDTVLHSLQQLEQEALQGQTPMNCHLCKFRLAVSAEVRAGSSHHHPHEPHDHHHGHGSHHHPHSHHHP
QHGHTHAAAGDPWAQLEGYHQRAWQVP

Specific function: Chelates cobalt to the cobalamin precursor as part of the anaerobic pathway to cobalamin biosynthesis [H]

COG id: COG2138

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiX family. CbiXL subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002762 [H]

Pfam domain/function: PF01903 CbiX [H]

EC number: =4.99.1.3 [H]

Molecular weight: Translated: 38697; Mature: 38697

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTLSVSPPLAVGQSPVVPLPLLLIGHGSRDPQGQQAFLELAQAYQALTPHRPVIPCFL
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
ELTQPTIAQGVEQCLAQGWQEIVVLPLLLFGARHNKFDVTMELDLLQTLYPQLRIHYGGP
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHEEEECCCC
LGIRIEILQLLRDRLAALMAAQPQRIPEAETVLLFVGRGSSDPEANAEACKLARLLWEGS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCC
GFAAVETCFIGITHPRLPVGLERALSWHPRRVIVLPYFLFTGVLVKKIEAAVEQQRQRQP
CCCEEHHEEEECCCCCCCCCHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
EIDWLMLPELGLVDTVLHSLQQLEQEALQGQTPMNCHLCKFRLAVSAEVRAGSSHHHPHE
CCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEEEEHHHCCCCCCCCCCC
PHDHHHGHGSHHHPHSHHHPQHGHTHAAAGDPWAQLEGYHQRAWQVP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHCCCC
>Mature Secondary Structure
MLNTLSVSPPLAVGQSPVVPLPLLLIGHGSRDPQGQQAFLELAQAYQALTPHRPVIPCFL
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
ELTQPTIAQGVEQCLAQGWQEIVVLPLLLFGARHNKFDVTMELDLLQTLYPQLRIHYGGP
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHEEEECCCC
LGIRIEILQLLRDRLAALMAAQPQRIPEAETVLLFVGRGSSDPEANAEACKLARLLWEGS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCC
GFAAVETCFIGITHPRLPVGLERALSWHPRRVIVLPYFLFTGVLVKKIEAAVEQQRQRQP
CCCEEHHEEEECCCCCCCCCHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
EIDWLMLPELGLVDTVLHSLQQLEQEALQGQTPMNCHLCKFRLAVSAEVRAGSSHHHPHE
CCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEEEEHHHCCCCCCCCCCC
PHDHHHGHGSHHHPHSHHHPQHGHTHAAAGDPWAQLEGYHQRAWQVP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 12917443 [H]