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The map label for this gene is pyrH [H]

Identifier: 86609733

GI number: 86609733

Start: 2396569

End: 2397330

Strand: Direct

Name: pyrH [H]

Synonym: CYB_2292

Alternate gene names: 86609733

Gene position: 2396569-2397330 (Clockwise)

Preceding gene: 86609732

Following gene: 86609734

Centisome position: 78.66

GC content: 60.24

Gene sequence:

>762_bases
ATGAAATATCGACGGATTCTACTGAAGTTGAGTGGTGAAGCCCTGATGGGGGAGCGCCCCTACGGGATCGACCCCGAGGT
CTTGAAGTCCATTGCCGGCGAAGTGGCCTCGGTGGTGCGGGCCGGTGTGCAGGTGGCGATTGTGGTGGGAGGGGGTAACA
TCTGGCGCGGGCGCAAAGAGGCGGCTGCCCAAGGGATGGATCAGGCTTCTGCCGACTACGTAGGGATGCTGGCCACCGTC
ATCAACGCCTTAACCCTGCAGGATGCCATTGAGCGAGCCGGGATCCCCACCCGGGTGCAGACGGCCATCGCCATGCAGGA
GGTGGCGGAGCCCTATATTCGTCGCCGCGCCATTCGTCACCTGGAAAAGGGGCGGGTGGTGATTTTTGGGGCAGGATCTG
GCAACCCCTTCTTCACCACCGATACCACTGCGGCCTTGCGGGCGGCGGAGATCGATGCCGAGGTGATTTTCAAAGCCACC
AAGGTGGACGGAGTTTACGATGCGGATCCCAAGACTCACCCTCAGGCCCGCCGCTACGATGTCCTCAGCTATCAGGATGT
GCTGAACCGCGATCTGCGGGTTATGGACAGCACCGCCATCGCCCTCTGCAAGGAAAATCAATTGCCCATCGTGGTCTTTG
ACCTGACTACCCCTGGCAATATTTATCGAGTGGTGCAGGGAGAACCCATCGGCACTTGGATCGGACAGCGGACGGTCGAG
AACAACGGGATCCCCAGCCCAGGAGAGTTGATCCCAAGTTAG

Upstream 100 bases:

>100_bases
AAGGTTGTTTTTGTCGAGATGCTCTGTCGGTCAATCCTGTGAGCGGAGCTAGTTCAACAAACCTGCTATCGTATGCAGGG
GTGGGCCGGAGCGGATAAGC

Downstream 100 bases:

>100_bases
GGGGGAAATCGGCCTTGAGAGTCCGGCGACGCCCTAGCCAGGATTGAGTCCGAAGGATAGCCTGGCTCAAGGGTGTGCTC
AGGCCGTTTGGAGGGAAAGG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MKYRRILLKLSGEALMGERPYGIDPEVLKSIAGEVASVVRAGVQVAIVVGGGNIWRGRKEAAAQGMDQASADYVGMLATV
INALTLQDAIERAGIPTRVQTAIAMQEVAEPYIRRRAIRHLEKGRVVIFGAGSGNPFFTTDTTAALRAAEIDAEVIFKAT
KVDGVYDADPKTHPQARRYDVLSYQDVLNRDLRVMDSTAIALCKENQLPIVVFDLTTPGNIYRVVQGEPIGTWIGQRTVE
NNGIPSPGELIPS

Sequences:

>Translated_253_residues
MKYRRILLKLSGEALMGERPYGIDPEVLKSIAGEVASVVRAGVQVAIVVGGGNIWRGRKEAAAQGMDQASADYVGMLATV
INALTLQDAIERAGIPTRVQTAIAMQEVAEPYIRRRAIRHLEKGRVVIFGAGSGNPFFTTDTTAALRAAEIDAEVIFKAT
KVDGVYDADPKTHPQARRYDVLSYQDVLNRDLRVMDSTAIALCKENQLPIVVFDLTTPGNIYRVVQGEPIGTWIGQRTVE
NNGIPSPGELIPS
>Mature_253_residues
MKYRRILLKLSGEALMGERPYGIDPEVLKSIAGEVASVVRAGVQVAIVVGGGNIWRGRKEAAAQGMDQASADYVGMLATV
INALTLQDAIERAGIPTRVQTAIAMQEVAEPYIRRRAIRHLEKGRVVIFGAGSGNPFFTTDTTAALRAAEIDAEVIFKAT
KVDGVYDADPKTHPQARRYDVLSYQDVLNRDLRVMDSTAIALCKENQLPIVVFDLTTPGNIYRVVQGEPIGTWIGQRTVE
NNGIPSPGELIPS

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=234, Percent_Identity=49.1452991452991, Blast_Score=232, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 27459; Mature: 27459

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYRRILLKLSGEALMGERPYGIDPEVLKSIAGEVASVVRAGVQVAIVVGGGNIWRGRKE
CCHHEEEEEECCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHH
AAAQGMDQASADYVGMLATVINALTLQDAIERAGIPTRVQTAIAMQEVAEPYIRRRAIRH
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LEKGRVVIFGAGSGNPFFTTDTTAALRAAEIDAEVIFKATKVDGVYDADPKTHPQARRYD
HHCCCEEEEECCCCCCEEECCHHHHHHHHHCCHHHEEEEECCCCEECCCCCCCCCCHHHH
VLSYQDVLNRDLRVMDSTAIALCKENQLPIVVFDLTTPGNIYRVVQGEPIGTWIGQRTVE
HHHHHHHHCHHHHHHHHHHHEEEECCCCCEEEEEECCCCCEEEEEECCCCHHHHCCEEEC
NNGIPSPGELIPS
CCCCCCCCCCCCC
>Mature Secondary Structure
MKYRRILLKLSGEALMGERPYGIDPEVLKSIAGEVASVVRAGVQVAIVVGGGNIWRGRKE
CCHHEEEEEECCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHH
AAAQGMDQASADYVGMLATVINALTLQDAIERAGIPTRVQTAIAMQEVAEPYIRRRAIRH
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LEKGRVVIFGAGSGNPFFTTDTTAALRAAEIDAEVIFKATKVDGVYDADPKTHPQARRYD
HHCCCEEEEECCCCCCEEECCHHHHHHHHHCCHHHEEEEECCCCEECCCCCCCCCCHHHH
VLSYQDVLNRDLRVMDSTAIALCKENQLPIVVFDLTTPGNIYRVVQGEPIGTWIGQRTVE
HHHHHHHHCHHHHHHHHHHHEEEECCCCCEEEEEECCCCCEEEEEECCCCHHHHCCEEEC
NNGIPSPGELIPS
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA