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The map label for this gene is typA [H]

Identifier: 86609702

GI number: 86609702

Start: 2361940

End: 2363757

Strand: Direct

Name: typA [H]

Synonym: CYB_2260

Alternate gene names: 86609702

Gene position: 2361940-2363757 (Clockwise)

Preceding gene: 86609701

Following gene: 86609711

Centisome position: 77.52

GC content: 59.79

Gene sequence:

>1818_bases
ATGTCACTCCCCATCCGCAACGTCGCCATCATTGCCCATGTTGACCATGGCAAAACCACCCTCGTGGATGCCCTGTTGCG
CCAGGCGGGCATCTTTCGGGAGGGGGAAGACATCCCCACCTGTGTGATGGACTGCAACACGCTGGAGCGGGAGCGGGGCA
TCACCATCTTGGCCAAAAACACAGCCGTCCGCTACGGCGAAACCTTGATCAACATCGTCGACACCCCTGGCCACGCCGAT
TTCGGGGGCGAGGTGGAGCGGGTGCTGGGGATGGTGGAGGGCTGCTTGTTGATCGTGGATGCCAACGAAGGCACGATGCC
GCAAACCCGCTTTGTGCTGCGCAAAGCCTTGGAGAAGGGCCTGCGCCCAATTGTGGTGGTCAACAAGATTGATCGGCCTC
GCGCCGAGCCCTACAAAGCCGTCGACAAGGTGCTGGATTTGTTCTTGGAGCTGGGGGCAGACGAAGACCAGTGCGACTTC
CCCTATCTATTTGCCTCTGGGTTGCGCGGCTTTGCCCTGGAAGAAGCCCATCTCAAAGACTTTCTGGAAGGGAAGTACAG
CGGATCCCTGGATATGAAGCCTCTTTTCGAGGCCATTCTCAAGCATGTCCCACCTCCCATTGGGGATCCCGGCAAGCCCC
TGCAGCTGCAGGTCACCACGCTGGAGTATTCGGAATACCTGGGCCGGATTGTGATCGGCAAGATCCACAACGGCACCATC
CGTCTGGGGGATCCATTGGCAGTGGTGAAAGAGGATGGATCCATTGCCAAGGGCAAAGTAACCAAGCTGTTCGGCTTTCA
GGGCCTGCAGCGCATCGAGCTGACGGAAGCCACCGCCGGCCACATTGTTGCTGTGGCGGGGTTTGCCGAGGCCAACATTG
GCCACACCCTCACCTCTCCCGAGAATCCCCAGGCTTTGCCGCTCATCAAAGTGGACGAGCCCACATTGCAGGTGATGATC
TGCGTCAACGACTCCCCCTTCGCCGGGCAAGAGGGTACTTTTGTAACTTCGCGGCAACTGCGGGAGCGCCTGATGCGGGA
GTTGGAAACCAACGTGGCGCTGCGGGTGGAAGAAACCGACTCGCCGGATCGCTTTTTGGTGTCGGGGCGAGGCGAGCTGC
ACCTGGGCATCCTGCTAGAAACCATGCGGCGGGAAGGCTATGAGTTTCAGGTGGGGCAACCGAAGGTAATTTTCCGCGAG
GTCAACGGCCAGCCCTATGAGCCCTATGAGTGTTTGGTGCTGGATGTGCCGGAAGCGACGGTGGGGGCCTGCATCGAGCG
GCTGGGGCAACGGCGGGGAGAAATGCAGAACATGATGGTGGGATCCGATGGTCGGGCTCAGCTGGAGTTTGTCATTCCGG
CGCGAGGGCTGATCGGCTTTCGAGGGGAGTTTATCCGCATCACCCGCGGCGAGGGGATCATGAGCCACAGCTTTCTGGAA
TACCGTCCCCTGACTTCTGAGATGGAAATGCGCCGCAACGGGGTGCTGATTGCTTTTGAAGAAGGGGTGGCCACCACCTA
CGCCCTGAAAAACGCCGAGGATCGGGGTGTGTTTTTCATTACCCCAGGTACCCGTGTTTACAAAGGGATGATCGTGGGCG
AGCACAACCGTCCCCAGGACTTGGAGTTGAACGTCTGCAAAACCAAGCAACTGACCAACCACCGAGCTGCGGGCGGGGAG
GAGCTGGTGCACTTGCAAGCGCCGGTGGAGATGACCCTGGAGCGGGCTTTGGAATACATCGGCGAGGATGAGCTGGTGGA
GATCACGCCCCAGTCGGTGCGCCTGCGCAAGGCACAGTTAACGCCCTCTCGCCGCTAG

Upstream 100 bases:

>100_bases
CTCAACTGTTTAGCGATGTAACGCTTCTTTGCGCTAAAGTTGTAAAGAGATCCCTAGGGCTCTCCTGCCTATAGGGCAAT
GTTCCCCTGGCTGATTATCT

Downstream 100 bases:

>100_bases
TTTTCTCAGCCAACTGGAAGAGAGCCTGGCTCACCACCGCCGCAGGTAAGAGGCCAAGTTGGGGAAATAGAACGCCCCCC
AAATCCCCAGCAGGATGACT

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 604

Protein sequence:

>605_residues
MSLPIRNVAIIAHVDHGKTTLVDALLRQAGIFREGEDIPTCVMDCNTLERERGITILAKNTAVRYGETLINIVDTPGHAD
FGGEVERVLGMVEGCLLIVDANEGTMPQTRFVLRKALEKGLRPIVVVNKIDRPRAEPYKAVDKVLDLFLELGADEDQCDF
PYLFASGLRGFALEEAHLKDFLEGKYSGSLDMKPLFEAILKHVPPPIGDPGKPLQLQVTTLEYSEYLGRIVIGKIHNGTI
RLGDPLAVVKEDGSIAKGKVTKLFGFQGLQRIELTEATAGHIVAVAGFAEANIGHTLTSPENPQALPLIKVDEPTLQVMI
CVNDSPFAGQEGTFVTSRQLRERLMRELETNVALRVEETDSPDRFLVSGRGELHLGILLETMRREGYEFQVGQPKVIFRE
VNGQPYEPYECLVLDVPEATVGACIERLGQRRGEMQNMMVGSDGRAQLEFVIPARGLIGFRGEFIRITRGEGIMSHSFLE
YRPLTSEMEMRRNGVLIAFEEGVATTYALKNAEDRGVFFITPGTRVYKGMIVGEHNRPQDLELNVCKTKQLTNHRAAGGE
ELVHLQAPVEMTLERALEYIGEDELVEITPQSVRLRKAQLTPSRR

Sequences:

>Translated_605_residues
MSLPIRNVAIIAHVDHGKTTLVDALLRQAGIFREGEDIPTCVMDCNTLERERGITILAKNTAVRYGETLINIVDTPGHAD
FGGEVERVLGMVEGCLLIVDANEGTMPQTRFVLRKALEKGLRPIVVVNKIDRPRAEPYKAVDKVLDLFLELGADEDQCDF
PYLFASGLRGFALEEAHLKDFLEGKYSGSLDMKPLFEAILKHVPPPIGDPGKPLQLQVTTLEYSEYLGRIVIGKIHNGTI
RLGDPLAVVKEDGSIAKGKVTKLFGFQGLQRIELTEATAGHIVAVAGFAEANIGHTLTSPENPQALPLIKVDEPTLQVMI
CVNDSPFAGQEGTFVTSRQLRERLMRELETNVALRVEETDSPDRFLVSGRGELHLGILLETMRREGYEFQVGQPKVIFRE
VNGQPYEPYECLVLDVPEATVGACIERLGQRRGEMQNMMVGSDGRAQLEFVIPARGLIGFRGEFIRITRGEGIMSHSFLE
YRPLTSEMEMRRNGVLIAFEEGVATTYALKNAEDRGVFFITPGTRVYKGMIVGEHNRPQDLELNVCKTKQLTNHRAAGGE
ELVHLQAPVEMTLERALEYIGEDELVEITPQSVRLRKAQLTPSRR
>Mature_604_residues
SLPIRNVAIIAHVDHGKTTLVDALLRQAGIFREGEDIPTCVMDCNTLERERGITILAKNTAVRYGETLINIVDTPGHADF
GGEVERVLGMVEGCLLIVDANEGTMPQTRFVLRKALEKGLRPIVVVNKIDRPRAEPYKAVDKVLDLFLELGADEDQCDFP
YLFASGLRGFALEEAHLKDFLEGKYSGSLDMKPLFEAILKHVPPPIGDPGKPLQLQVTTLEYSEYLGRIVIGKIHNGTIR
LGDPLAVVKEDGSIAKGKVTKLFGFQGLQRIELTEATAGHIVAVAGFAEANIGHTLTSPENPQALPLIKVDEPTLQVMIC
VNDSPFAGQEGTFVTSRQLRERLMRELETNVALRVEETDSPDRFLVSGRGELHLGILLETMRREGYEFQVGQPKVIFREV
NGQPYEPYECLVLDVPEATVGACIERLGQRRGEMQNMMVGSDGRAQLEFVIPARGLIGFRGEFIRITRGEGIMSHSFLEY
RPLTSEMEMRRNGVLIAFEEGVATTYALKNAEDRGVFFITPGTRVYKGMIVGEHNRPQDLELNVCKTKQLTNHRAAGGEE
LVHLQAPVEMTLERALEYIGEDELVEITPQSVRLRKAQLTPSRR

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=321, Percent_Identity=31.4641744548287, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI94966754, Length=132, Percent_Identity=44.6969696969697, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI4503483, Length=144, Percent_Identity=38.1944444444444, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI18390331, Length=145, Percent_Identity=39.3103448275862, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI310132016, Length=110, Percent_Identity=40.9090909090909, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI310110807, Length=110, Percent_Identity=40.9090909090909, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI310123363, Length=110, Percent_Identity=40.9090909090909, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI34147630, Length=249, Percent_Identity=31.3253012048193, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI217272892, Length=155, Percent_Identity=35.4838709677419, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI217272894, Length=155, Percent_Identity=35.4838709677419, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI19923640, Length=142, Percent_Identity=36.6197183098592, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI25306287, Length=142, Percent_Identity=36.6197183098592, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI25306283, Length=142, Percent_Identity=36.6197183098592, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI94966752, Length=83, Percent_Identity=48.1927710843374, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI48994988, Length=605, Percent_Identity=51.5702479338843, Blast_Score=618, Evalue=1e-178,
Organism=Escherichia coli, GI1788922, Length=549, Percent_Identity=29.8724954462659, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI1789738, Length=494, Percent_Identity=25.9109311740891, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1790835, Length=145, Percent_Identity=31.7241379310345, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1790412, Length=283, Percent_Identity=27.9151943462898, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789737, Length=283, Percent_Identity=27.9151943462898, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17557151, Length=320, Percent_Identity=31.5625, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17506493, Length=243, Percent_Identity=30.4526748971193, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17533571, Length=143, Percent_Identity=43.3566433566434, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71988819, Length=132, Percent_Identity=39.3939393939394, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71988811, Length=132, Percent_Identity=39.3939393939394, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17556745, Length=142, Percent_Identity=39.4366197183099, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17552882, Length=210, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17556456, Length=287, Percent_Identity=29.9651567944251, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32566629, Length=274, Percent_Identity=27.7372262773723, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323320, Length=520, Percent_Identity=27.5, Blast_Score=138, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6324707, Length=204, Percent_Identity=36.2745098039216, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320593, Length=204, Percent_Identity=36.2745098039216, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324761, Length=284, Percent_Identity=30.6338028169014, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322359, Length=148, Percent_Identity=37.8378378378378, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323098, Length=149, Percent_Identity=34.8993288590604, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324166, Length=142, Percent_Identity=38.0281690140845, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI78706572, Length=524, Percent_Identity=26.1450381679389, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28574573, Length=137, Percent_Identity=40.8759124087591, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24582462, Length=145, Percent_Identity=40, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585711, Length=150, Percent_Identity=40, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24585713, Length=150, Percent_Identity=40, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24585709, Length=150, Percent_Identity=40, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357743, Length=206, Percent_Identity=34.4660194174757, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI221458488, Length=147, Percent_Identity=40.1360544217687, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281363316, Length=375, Percent_Identity=28.8, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17864358, Length=375, Percent_Identity=28.8, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI19921738, Length=240, Percent_Identity=31.6666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28572034, Length=285, Percent_Identity=29.1228070175439, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 67203; Mature: 67072

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPIRNVAIIAHVDHGKTTLVDALLRQAGIFREGEDIPTCVMDCNTLERERGITILAKN
CCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHCCEEEEECC
TAVRYGETLINIVDTPGHADFGGEVERVLGMVEGCLLIVDANEGTMPQTRFVLRKALEKG
CEEHHCCEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHC
LRPIVVVNKIDRPRAEPYKAVDKVLDLFLELGADEDQCDFPYLFASGLRGFALEEAHLKD
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEECHHHHHH
FLEGKYSGSLDMKPLFEAILKHVPPPIGDPGKPLQLQVTTLEYSEYLGRIVIGKIHNGTI
HHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEHHHHCCEEEEEEEECCEE
RLGDPLAVVKEDGSIAKGKVTKLFGFQGLQRIELTEATAGHIVAVAGFAEANIGHTLTSP
EECCCEEEEECCCCCCCCCHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCC
ENPQALPLIKVDEPTLQVMICVNDSPFAGQEGTFVTSRQLRERLMRELETNVALRVEETD
CCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHCCCEEEEEECCC
SPDRFLVSGRGELHLGILLETMRREGYEFQVGQPKVIFREVNGQPYEPYECLVLDVPEAT
CCCEEEEECCCCEEHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCEEEEEECCCHH
VGACIERLGQRRGEMQNMMVGSDGRAQLEFVIPARGLIGFRGEFIRITRGEGIMSHSFLE
HHHHHHHHHHHHCHHHHEEECCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCE
YRPLTSEMEMRRNGVLIAFEEGVATTYALKNAEDRGVFFITPGTRVYKGMIVGEHNRPQD
ECCCCHHHHHHHCCEEEEEECCCEEEEEECCCCCCCEEEECCCCEEEEEEEEECCCCCCC
LELNVCKTKQLTNHRAAGGEELVHLQAPVEMTLERALEYIGEDELVEITPQSVRLRKAQL
CEEEEECCHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEECCHHHEEEEECC
TPSRR
CCCCC
>Mature Secondary Structure 
SLPIRNVAIIAHVDHGKTTLVDALLRQAGIFREGEDIPTCVMDCNTLERERGITILAKN
CCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHCCEEEEECC
TAVRYGETLINIVDTPGHADFGGEVERVLGMVEGCLLIVDANEGTMPQTRFVLRKALEKG
CEEHHCCEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHC
LRPIVVVNKIDRPRAEPYKAVDKVLDLFLELGADEDQCDFPYLFASGLRGFALEEAHLKD
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEECHHHHHH
FLEGKYSGSLDMKPLFEAILKHVPPPIGDPGKPLQLQVTTLEYSEYLGRIVIGKIHNGTI
HHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEHHHHCCEEEEEEEECCEE
RLGDPLAVVKEDGSIAKGKVTKLFGFQGLQRIELTEATAGHIVAVAGFAEANIGHTLTSP
EECCCEEEEECCCCCCCCCHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCC
ENPQALPLIKVDEPTLQVMICVNDSPFAGQEGTFVTSRQLRERLMRELETNVALRVEETD
CCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHCCCEEEEEECCC
SPDRFLVSGRGELHLGILLETMRREGYEFQVGQPKVIFREVNGQPYEPYECLVLDVPEAT
CCCEEEEECCCCEEHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCEEEEEECCCHH
VGACIERLGQRRGEMQNMMVGSDGRAQLEFVIPARGLIGFRGEFIRITRGEGIMSHSFLE
HHHHHHHHHHHHCHHHHEEECCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCE
YRPLTSEMEMRRNGVLIAFEEGVATTYALKNAEDRGVFFITPGTRVYKGMIVGEHNRPQD
ECCCCHHHHHHHCCEEEEEECCCEEEEEECCCCCCCEEEECCCCEEEEEEEEECCCCCCC
LELNVCKTKQLTNHRAAGGEELVHLQAPVEMTLERALEYIGEDELVEITPQSVRLRKAQL
CEEEEECCHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEECCHHHEEEEECC
TPSRR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]