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The map label for this gene is cobI [H]

Identifier: 86609635

GI number: 86609635

Start: 2293808

End: 2294563

Strand: Reverse

Name: cobI [H]

Synonym: CYB_2189

Alternate gene names: 86609635

Gene position: 2294563-2293808 (Counterclockwise)

Preceding gene: 86609636

Following gene: 86609634

Centisome position: 75.31

GC content: 61.9

Gene sequence:

>756_bases
ATGGGTCTGGGAACCTTTTGGGGGATCAGTGCTGGAGCAGGGGATCCCGACTGGATCACGGTCAAAGCAGCCCGCATCCT
CAGCACGGTCAACTGGGTGGCCTGTCCCCAAAATGCCGCCGGCCAGCCGGGCCTGGCCTATCAGATTGTGCGCCCTTGGC
TGCGACCGGAACAAACCCTCTTGCCGCTTCGCCTGCCCTTTGTCACCCGGTCGGAAGTCCTGCAAGCTGCCTGGCAAGCG
GCTGCCCAGCAACTGGCCCCACTCCTAGAAAGGGGAGAAGATGTCGCCTTCATCTGTGAGGGAGACGTGGGCCTCTACAG
CACCTTTGCCTACGTGGCCCAAGCCCTGCGGCAGCGGATCCCCGCCTTGCCCATCCAGGCCATACCGGGGGTGTGCTCTC
CCTTAGCCGCTGCTGCTGCCCTGGGATCCCCCTTGGTGCTCGGCTCCGAGAAATTGGCGATTTTACCGGCTCTGTTTGCC
CTCTCGGAACTGGAGCAGGCTTGTGCCTGGGCTGAGGTAGTCGTCCTCATGAAAGTGGCCTCTGTCTACCCTCAGGTTTG
GCAGTGGCTGGCCGAAAGAGGTTGGCTGCAACAGGCCAGCTTGGTGGTCTGGGCCGGCTGGCCTCAGCAAACCCTCTTCC
CCACCCTGGAAGGACTGGCCGACTACCGGCCCCCCTACTTTTCCCTGCTGATCCTGCGTTCTCGGCCCCGAAATCAAGAT
TCTCTTAACCTGGAAAACGAGCTACAGCTGGAATGA

Upstream 100 bases:

>100_bases
GGAGAAGTTCCTATCTTTGCGCAACTCCTTGCAGGAAGCCTTGGATCGCCTGAAGGAAGGAAGTACGGGCAGTACAGAGA
CCGCCTGATACGTAATAAGT

Downstream 100 bases:

>100_bases
GTTTTCTAGGATAGGGAATGAGTTCCTTCCGGCGATTAAGCCCGAAGCAGGGGTTGGTCGTTGTTTTTTTGCGTTTATTT
CTGTTTAGCTCAAGGCTCGC

Product: precorrin-2 methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MGLGTFWGISAGAGDPDWITVKAARILSTVNWVACPQNAAGQPGLAYQIVRPWLRPEQTLLPLRLPFVTRSEVLQAAWQA
AAQQLAPLLERGEDVAFICEGDVGLYSTFAYVAQALRQRIPALPIQAIPGVCSPLAAAAALGSPLVLGSEKLAILPALFA
LSELEQACAWAEVVVLMKVASVYPQVWQWLAERGWLQQASLVVWAGWPQQTLFPTLEGLADYRPPYFSLLILRSRPRNQD
SLNLENELQLE

Sequences:

>Translated_251_residues
MGLGTFWGISAGAGDPDWITVKAARILSTVNWVACPQNAAGQPGLAYQIVRPWLRPEQTLLPLRLPFVTRSEVLQAAWQA
AAQQLAPLLERGEDVAFICEGDVGLYSTFAYVAQALRQRIPALPIQAIPGVCSPLAAAAALGSPLVLGSEKLAILPALFA
LSELEQACAWAEVVVLMKVASVYPQVWQWLAERGWLQQASLVVWAGWPQQTLFPTLEGLADYRPPYFSLLILRSRPRNQD
SLNLENELQLE
>Mature_250_residues
GLGTFWGISAGAGDPDWITVKAARILSTVNWVACPQNAAGQPGLAYQIVRPWLRPEQTLLPLRLPFVTRSEVLQAAWQAA
AQQLAPLLERGEDVAFICEGDVGLYSTFAYVAQALRQRIPALPIQAIPGVCSPLAAAAALGSPLVLGSEKLAILPALFAL
SELEQACAWAEVVVLMKVASVYPQVWQWLAERGWLQQASLVVWAGWPQQTLFPTLEGLADYRPPYFSLLILRSRPRNQDS
LNLENELQLE

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 27467; Mature: 27336

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLGTFWGISAGAGDPDWITVKAARILSTVNWVACPQNAAGQPGLAYQIVRPWLRPEQTL
CCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCE
LPLRLPFVTRSEVLQAAWQAAAQQLAPLLERGEDVAFICEGDVGLYSTFAYVAQALRQRI
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHC
PALPIQAIPGVCSPLAAAAALGSPLVLGSEKLAILPALFALSELEQACAWAEVVVLMKVA
CCCCHHHCCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVYPQVWQWLAERGWLQQASLVVWAGWPQQTLFPTLEGLADYRPPYFSLLILRSRPRNQD
HHHHHHHHHHHHHCCHHHCCEEEEECCCCHHHHHHHHHHHHCCCCHHEEEEECCCCCCCC
SLNLENELQLE
CCCCCCCCCCC
>Mature Secondary Structure 
GLGTFWGISAGAGDPDWITVKAARILSTVNWVACPQNAAGQPGLAYQIVRPWLRPEQTL
CCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCE
LPLRLPFVTRSEVLQAAWQAAAQQLAPLLERGEDVAFICEGDVGLYSTFAYVAQALRQRI
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHC
PALPIQAIPGVCSPLAAAAALGSPLVLGSEKLAILPALFALSELEQACAWAEVVVLMKVA
CCCCHHHCCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVYPQVWQWLAERGWLQQASLVVWAGWPQQTLFPTLEGLADYRPPYFSLLILRSRPRNQD
HHHHHHHHHHHHHCCHHHCCEEEEECCCCHHHHHHHHHHHHCCCCHHEEEEECCCCCCCC
SLNLENELQLE
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]