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The map label for this gene is pilC [H]

Identifier: 86609588

GI number: 86609588

Start: 2238427

End: 2239653

Strand: Reverse

Name: pilC [H]

Synonym: CYB_2141

Alternate gene names: 86609588

Gene position: 2239653-2238427 (Counterclockwise)

Preceding gene: 86609589

Following gene: 86609587

Centisome position: 73.51

GC content: 59.25

Gene sequence:

>1227_bases
ATGCCGCGCTACAAGGTTCGGGGGTTAAAGGCCGGTCAGCCGGTACGCCTGACGGTGGTGGCCAACAGCTTGACCGAAGT
TCGTGCACGGCTGCGCCGAGACGGGATTTTTGCCAAACAGGAAGACATTCAGGAGGAGAAACCCTTCTTTTCCTTGGATA
CGTCTTTCGATTTCTCAATGCTGGGATCCATCGACATTCGCGACAAGGCAGTGTTCTCCCGGCAATTTGCTGCCTTGATC
AACGCCGGCGTGTCGATGGTGCGCTCTCTCACCATCATGGAGGAGCAAACCGGCAACCCCAAACTCAAAAAGTACCTGCG
GGCTATCCGAGCGGAGGTGGAGGCGGGGAAAAACCTCTCCGACTCCATCCGCCCTTATCCCGACGCCTTCGACGGCCTCT
ACTGCAGCATGGTGCAGGCGGGGGAGGTGGGCGGCGTGCTGGACGAAGTGCTCAACCGCCTGGCCAAGCTGCTGGAGGAC
ATGGATCGCCTGCAGAAGCAGATCAAGTCAGCCATGACCTACCCGGTGGTGGTGACGATCTTGGCTGTCTTGATTTTCTT
GGGCATGGTGCTGTTCATCTTGCCCACGTTTGAGAGCATCTACAACGACTTGGGTGGGGAGCTGCCCGCCTTTACCCAGT
TTTTCATCAACATCAGCAAGTTCCTACGCACGCCCCAGTACAGCTTGGGGCTGGTGGGCTTTCTAGGGGCCGTCTATTTT
GCTTTCCGGCGCTTTTACCGCACCCCTGCCGGCAAGGAGACCATCGACGCGCTGGCCCTCAAGCTCCCTATCTTCGGGGA
TCTGATCCAGAAGTCGGCGGTGGCTCGCTTCTGCCGCACCTTTGGCGCTCTCACCCGCTCCGGGGTGCCGGTGCTGACTT
CCTTGGAAATTGTGCGCGACACCTCCGGCAACCAGGTGGTGGCCAACGCCATTGACGCCGCCCGCCAATCCATCTCAGAG
GGAGGGCAGATTGCCCCTGCTCTGGACAAGGCCAAGGTCTTCCCAGTCATGGCCATTCAGATGATCAGCGTGGGGGAAGA
GACAGGGGAGCTGGACGCGATGCTGATGAAGACGGCGGATTTCTACGAGCTGGAGGTGGAGGAGGCGGTACGCGCCCTCA
CCAGCCTGCTGGAGCCGTTGATGATCGTGATCCTGGGCGGTATGGTGGGCTGCATTATCGTGGCCATGTACCTGCCCATG
TTCAACGTGTTCGAGTTGGTGAAGTAG

Upstream 100 bases:

>100_bases
ATTGTTGATCTGCCCAAGGTTTGGGCTGACTTCTCTTTTGCACCTGCGAAACATTTAAAGCCATTTCGTTATTTAGAGCG
ATCTAGCCGGGGGTACAGCC

Downstream 100 bases:

>100_bases
CCGGAAGGGATCCCTCGAAGTTGGACGGTAAATTCTACACAGGTTCTGCTGCTGGCTCCCGATAGTTTGGGTCGAAAGAG
GCAAAGTCAGAGCAACGGAG

Product: type IV pilus assembly protein PilC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MPRYKVRGLKAGQPVRLTVVANSLTEVRARLRRDGIFAKQEDIQEEKPFFSLDTSFDFSMLGSIDIRDKAVFSRQFAALI
NAGVSMVRSLTIMEEQTGNPKLKKYLRAIRAEVEAGKNLSDSIRPYPDAFDGLYCSMVQAGEVGGVLDEVLNRLAKLLED
MDRLQKQIKSAMTYPVVVTILAVLIFLGMVLFILPTFESIYNDLGGELPAFTQFFINISKFLRTPQYSLGLVGFLGAVYF
AFRRFYRTPAGKETIDALALKLPIFGDLIQKSAVARFCRTFGALTRSGVPVLTSLEIVRDTSGNQVVANAIDAARQSISE
GGQIAPALDKAKVFPVMAIQMISVGEETGELDAMLMKTADFYELEVEEAVRALTSLLEPLMIVILGGMVGCIIVAMYLPM
FNVFELVK

Sequences:

>Translated_408_residues
MPRYKVRGLKAGQPVRLTVVANSLTEVRARLRRDGIFAKQEDIQEEKPFFSLDTSFDFSMLGSIDIRDKAVFSRQFAALI
NAGVSMVRSLTIMEEQTGNPKLKKYLRAIRAEVEAGKNLSDSIRPYPDAFDGLYCSMVQAGEVGGVLDEVLNRLAKLLED
MDRLQKQIKSAMTYPVVVTILAVLIFLGMVLFILPTFESIYNDLGGELPAFTQFFINISKFLRTPQYSLGLVGFLGAVYF
AFRRFYRTPAGKETIDALALKLPIFGDLIQKSAVARFCRTFGALTRSGVPVLTSLEIVRDTSGNQVVANAIDAARQSISE
GGQIAPALDKAKVFPVMAIQMISVGEETGELDAMLMKTADFYELEVEEAVRALTSLLEPLMIVILGGMVGCIIVAMYLPM
FNVFELVK
>Mature_407_residues
PRYKVRGLKAGQPVRLTVVANSLTEVRARLRRDGIFAKQEDIQEEKPFFSLDTSFDFSMLGSIDIRDKAVFSRQFAALIN
AGVSMVRSLTIMEEQTGNPKLKKYLRAIRAEVEAGKNLSDSIRPYPDAFDGLYCSMVQAGEVGGVLDEVLNRLAKLLEDM
DRLQKQIKSAMTYPVVVTILAVLIFLGMVLFILPTFESIYNDLGGELPAFTQFFINISKFLRTPQYSLGLVGFLGAVYFA
FRRFYRTPAGKETIDALALKLPIFGDLIQKSAVARFCRTFGALTRSGVPVLTSLEIVRDTSGNQVVANAIDAARQSISEG
GQIAPALDKAKVFPVMAIQMISVGEETGELDAMLMKTADFYELEVEEAVRALTSLLEPLMIVILGGMVGCIIVAMYLPMF
NVFELVK

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=406, Percent_Identity=25.615763546798, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1786295, Length=331, Percent_Identity=31.1178247734139, Blast_Score=163, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 45096; Mature: 44964

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PRYKVRGLKAGQPVRLTVVANSLTEVRARLRRDGIFAKQEDIQEEKPFFSLDTSFDFSM
CCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEECCCCCHHH
LGSIDIRDKAVFSRQFAALINAGVSMVRSLTIMEEQTGNPKLKKYLRAIRAEVEAGKNLS
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
DSIRPYPDAFDGLYCSMVQAGEVGGVLDEVLNRLAKLLEDMDRLQKQIKSAMTYPVVVTI
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LAVLIFLGMVLFILPTFESIYNDLGGELPAFTQFFINISKFLRTPQYSLGLVGFLGAVYF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AFRRFYRTPAGKETIDALALKLPIFGDLIQKSAVARFCRTFGALTRSGVPVLTSLEIVRD
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
TSGNQVVANAIDAARQSISEGGQIAPALDKAKVFPVMAIQMISVGEETGELDAMLMKTAD
CCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCH
FYELEVEEAVRALTSLLEPLMIVILGGMVGCIIVAMYLPMFNVFELVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]