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The map label for this gene is mpg1 [H]

Identifier: 86609570

GI number: 86609570

Start: 2215664

End: 2216611

Strand: Reverse

Name: mpg1 [H]

Synonym: CYB_2123

Alternate gene names: 86609570

Gene position: 2216611-2215664 (Counterclockwise)

Preceding gene: 86609576

Following gene: 86609569

Centisome position: 72.75

GC content: 59.18

Gene sequence:

>948_bases
ATGCAAGCGGTGATCTTGGCGGGTGGGAAAGGAACTCGTTTACGGCCCTTTACCTTTTTGCAGCCTAAGCCTTTGTTGCC
CCTCCTGGATGTGCCCTTTTTGGAGTGGCTGATCGGGCGCTGCCGCCGAGCCGGCCTGACGGATATTTTGCTCAGCGTGG
GTTATCTGGGCCAACAAATTGAGGCTGCTCTGGGAGATGGCGCTGCTTTGGGGGTGAAGCTCCGCTACATTCCCGAAGAG
ACGCCTTTGGATACGGCAGGAGCCTTGGTGCTGGCTCAGCCCTATTTCACCGGGGATCCCTTGGTGGTCTTCAATGCCGA
CATCCTCACGGATCTGGATTTGCAGGCGTTGATGCAATGTCATGTGCAGAGCAAGGCCATTGCCACCCTCACCCTCGCCC
GCGTGGAAGATATCACCGCCTATGGCCTGGTGGAAGTTGGGGAAGGGGGCCAGATCCAATCTTTTCGGGAAAAACCCACC
CCTGCAGAAGCCCTCACCCTCACCACCGACACGATCAACGCCGGCACCTATGTCTTGGATCCAGCCATTTTTAAAGACTA
CCCCAGTGGGGATCCCCTCAGCTTCGAGCGGCGTGTCTTCCCCGATTTGCTCAGGCAAGGGCACCGGCTGCAAGCTTATC
TCCACACAGGCTACTGGCGGGATCTGGGCACGCCGGCCAGCTACTACCACGGCCAACTGGACATTCTCCTGGGTCGAATG
ACGGATTTTCCCCTGGAAGATGTGCAGCAACAGGCGCCGGGGATATGGGTGCACAAAACGGCTGAGATCCATCCCAGCGC
TCAACTGCACGCCCCCTGCTACATCGGCGCCCACACCCGTTTGGGATCCCAAGCTCAGATTCCGGCAGGCACCATCCTCG
GCAGCCACAGCTGGGTAAATGGATCCCTGCAGCCGGGAGCCTACGGGCCGAGAGTCCTGGTAGTGTAG

Upstream 100 bases:

>100_bases
GGGTAGCAGAAAACATTTGGCTCGACCCAATGGATCCCCCTTAGCAATTGGGCGGAGAGGATGTCAATATCTTTGGAAGA
GAACGGGGTTGAGGGTGGTT

Downstream 100 bases:

>100_bases
GTTAAGTGCAAGTTAAGTTCACAACCATCTACGACAAAGCCATCAACAGATGGAGTTACCACAAACTGGGGAACGCTGGG
ATCCCTACCTTGCCTCTGTG

Product: nucleotidyl transferase family protein

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MQAVILAGGKGTRLRPFTFLQPKPLLPLLDVPFLEWLIGRCRRAGLTDILLSVGYLGQQIEAALGDGAALGVKLRYIPEE
TPLDTAGALVLAQPYFTGDPLVVFNADILTDLDLQALMQCHVQSKAIATLTLARVEDITAYGLVEVGEGGQIQSFREKPT
PAEALTLTTDTINAGTYVLDPAIFKDYPSGDPLSFERRVFPDLLRQGHRLQAYLHTGYWRDLGTPASYYHGQLDILLGRM
TDFPLEDVQQQAPGIWVHKTAEIHPSAQLHAPCYIGAHTRLGSQAQIPAGTILGSHSWVNGSLQPGAYGPRVLVV

Sequences:

>Translated_315_residues
MQAVILAGGKGTRLRPFTFLQPKPLLPLLDVPFLEWLIGRCRRAGLTDILLSVGYLGQQIEAALGDGAALGVKLRYIPEE
TPLDTAGALVLAQPYFTGDPLVVFNADILTDLDLQALMQCHVQSKAIATLTLARVEDITAYGLVEVGEGGQIQSFREKPT
PAEALTLTTDTINAGTYVLDPAIFKDYPSGDPLSFERRVFPDLLRQGHRLQAYLHTGYWRDLGTPASYYHGQLDILLGRM
TDFPLEDVQQQAPGIWVHKTAEIHPSAQLHAPCYIGAHTRLGSQAQIPAGTILGSHSWVNGSLQPGAYGPRVLVV
>Mature_315_residues
MQAVILAGGKGTRLRPFTFLQPKPLLPLLDVPFLEWLIGRCRRAGLTDILLSVGYLGQQIEAALGDGAALGVKLRYIPEE
TPLDTAGALVLAQPYFTGDPLVVFNADILTDLDLQALMQCHVQSKAIATLTLARVEDITAYGLVEVGEGGQIQSFREKPT
PAEALTLTTDTINAGTYVLDPAIFKDYPSGDPLSFERRVFPDLLRQGHRLQAYLHTGYWRDLGTPASYYHGQLDILLGRM
TDFPLEDVQQQAPGIWVHKTAEIHPSAQLHAPCYIGAHTRLGSQAQIPAGTILGSHSWVNGSLQPGAYGPRVLVV

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=323, Percent_Identity=31.5789473684211, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI11761619, Length=323, Percent_Identity=31.5789473684211, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI31881779, Length=338, Percent_Identity=27.5147928994083, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI45447090, Length=338, Percent_Identity=27.5147928994083, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1788351, Length=233, Percent_Identity=30.9012875536481, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1790224, Length=165, Percent_Identity=29.6969696969697, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787488, Length=271, Percent_Identity=25.0922509225092, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI133931050, Length=323, Percent_Identity=32.8173374613003, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17509979, Length=310, Percent_Identity=29.0322580645161, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17509981, Length=299, Percent_Identity=28.0936454849498, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320148, Length=310, Percent_Identity=29.0322580645161, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21355443, Length=320, Percent_Identity=31.5625, Blast_Score=157, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24644084, Length=320, Percent_Identity=31.5625, Blast_Score=157, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24653912, Length=201, Percent_Identity=35.8208955223881, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 34269; Mature: 34269

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAVILAGGKGTRLRPFTFLQPKPLLPLLDVPFLEWLIGRCRRAGLTDILLSVGYLGQQI
CCEEEEECCCCCEECCEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EAALGDGAALGVKLRYIPEETPLDTAGALVLAQPYFTGDPLVVFNADILTDLDLQALMQC
HHHHCCCEEEEEEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEECHHHCCCCHHHHHHH
HVQSKAIATLTLARVEDITAYGLVEVGEGGQIQSFREKPTPAEALTLTTDTINAGTYVLD
HHCCHHHHEEEHHHHHHHHEEEEEEECCCCCCCHHHCCCCCCCEEEEEECCCCCCEEEEC
PAIFKDYPSGDPLSFERRVFPDLLRQGHRLQAYLHTGYWRDLGTPASYYHGQLDILLGRM
HHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCHHCCCCCHHHHCCEEEEEEECC
TDFPLEDVQQQAPGIWVHKTAEIHPSAQLHAPCYIGAHTRLGSQAQIPAGTILGSHSWVN
CCCCHHHHHHHCCCEEEEEEEEECCCCEECCCEEEECCCCCCCCCCCCCEEEECCCCEEC
GSLQPGAYGPRVLVV
CCCCCCCCCCEEEEC
>Mature Secondary Structure
MQAVILAGGKGTRLRPFTFLQPKPLLPLLDVPFLEWLIGRCRRAGLTDILLSVGYLGQQI
CCEEEEECCCCCEECCEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EAALGDGAALGVKLRYIPEETPLDTAGALVLAQPYFTGDPLVVFNADILTDLDLQALMQC
HHHHCCCEEEEEEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEECHHHCCCCHHHHHHH
HVQSKAIATLTLARVEDITAYGLVEVGEGGQIQSFREKPTPAEALTLTTDTINAGTYVLD
HHCCHHHHEEEHHHHHHHHEEEEEEECCCCCCCHHHCCCCCCCEEEEEECCCCCCEEEEC
PAIFKDYPSGDPLSFERRVFPDLLRQGHRLQAYLHTGYWRDLGTPASYYHGQLDILLGRM
HHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCHHCCCCCHHHHCCEEEEEEECC
TDFPLEDVQQQAPGIWVHKTAEIHPSAQLHAPCYIGAHTRLGSQAQIPAGTILGSHSWVN
CCCCHHHHHHHCCCEEEEEEEEECCCCEECCCEEEECCCCCCCCCCCCCEEEECCCCEEC
GSLQPGAYGPRVLVV
CCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]