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The map label for this gene is phoP [H]

Identifier: 86609479

GI number: 86609479

Start: 2133374

End: 2134093

Strand: Reverse

Name: phoP [H]

Synonym: CYB_2031

Alternate gene names: 86609479

Gene position: 2134093-2133374 (Counterclockwise)

Preceding gene: 86609490

Following gene: 86609477

Centisome position: 70.05

GC content: 56.11

Gene sequence:

>720_bases
ATGTCACGCATCCTCATCATCGATGATGATCCCAGCATTTGTGCTCTACTGCAGCGGTACTTGCAGCGGCAGGGGTATTC
GGTTGAGGTGGCGATGACGGGGGCCGAGGGCTTACAGCAGTTGCGCGCTTTTCAGCCGGCCTTGGTAATTTTGGATCTGA
ACTTGCCGGATGTGAGCGGCTACGATCTCTGCCAGCAAATGCAAAAAGAGACCGGCGTGTACGTGTTGATGTTGACCAGC
CGCGTCAGCCCTGCTGATAAGTTGCACGGATTCCAGTTGGGGGCAGATGACTACCTGACCAAGCCCTTCAGCCTGCCGGA
GTTACAGGCGCGAGTGCAAGCCATTCTGCGGCGGCAACGCATGAAGACCGAAGTTGCCAGCGCACCGGTCTTGACCTTTG
CCTCTTTGGTAATCGACCCGGAAACCCGAGCAGTCATCCGCGAGCAGCGCCTGATCAACTTAACAGCACTGGAGTTCGAT
TTGCTCTATGCTATGGCTCGACATCCGGGGCGGGTTTGGCGACGGGCTGAGCTGATTCAAGAGGTGTGGGATTTTAACCA
CGAGGGAGATGAACGGGTGGTCGATGTCCACATTGGCCAAATTCGCAAGAAACTAGAGACTGATACCAGCCAACCGGAGT
TGATCCGCACCGTGCGTGGAGTTGGCTACAAGTTTGAGCCCCCCGCTCCGAAGGAGGGATGGGGAGAGGAAAAACCTTAA

Upstream 100 bases:

>100_bases
CACCTCTGCACGATTGTTGCCCATGAGCTGCCGAAGGGATCCCCACACCCCAACGCCCTGCAACCTTGTCTCCTGCTGAC
TTCGAGAGTGCCAAGCTGCC

Downstream 100 bases:

>100_bases
CCCCCAAATAACTCTCCCCTCTTCACGTTGGGAGAGGGGCCAGGGGTGAGGGCCCGTTAATCCAAGCGGCGGCCTGTCAA
ACGCACAAAAATGTCTTCTA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSRILIIDDDPSICALLQRYLQRQGYSVEVAMTGAEGLQQLRAFQPALVILDLNLPDVSGYDLCQQMQKETGVYVLMLTS
RVSPADKLHGFQLGADDYLTKPFSLPELQARVQAILRRQRMKTEVASAPVLTFASLVIDPETRAVIREQRLINLTALEFD
LLYAMARHPGRVWRRAELIQEVWDFNHEGDERVVDVHIGQIRKKLETDTSQPELIRTVRGVGYKFEPPAPKEGWGEEKP

Sequences:

>Translated_239_residues
MSRILIIDDDPSICALLQRYLQRQGYSVEVAMTGAEGLQQLRAFQPALVILDLNLPDVSGYDLCQQMQKETGVYVLMLTS
RVSPADKLHGFQLGADDYLTKPFSLPELQARVQAILRRQRMKTEVASAPVLTFASLVIDPETRAVIREQRLINLTALEFD
LLYAMARHPGRVWRRAELIQEVWDFNHEGDERVVDVHIGQIRKKLETDTSQPELIRTVRGVGYKFEPPAPKEGWGEEKP
>Mature_238_residues
SRILIIDDDPSICALLQRYLQRQGYSVEVAMTGAEGLQQLRAFQPALVILDLNLPDVSGYDLCQQMQKETGVYVLMLTSR
VSPADKLHGFQLGADDYLTKPFSLPELQARVQAILRRQRMKTEVASAPVLTFASLVIDPETRAVIREQRLINLTALEFDL
LYAMARHPGRVWRRAELIQEVWDFNHEGDERVVDVHIGQIRKKLETDTSQPELIRTVRGVGYKFEPPAPKEGWGEEKP

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=37.0044052863436, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=34.6320346320346, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=34.2222222222222, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=35.1694915254237, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=35.8744394618834, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=34.9557522123894, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.9775784753363, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=35.2422907488987, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=33.4801762114537, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=35.1111111111111, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=30.379746835443, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=34.6846846846847, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=32.3008849557522, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=33.7777777777778, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788550, Length=126, Percent_Identity=30.952380952381, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790437, Length=151, Percent_Identity=27.8145695364238, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=115, Percent_Identity=33.0434782608696, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788905, Length=102, Percent_Identity=39.2156862745098, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27197; Mature: 27066

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRILIIDDDPSICALLQRYLQRQGYSVEVAMTGAEGLQQLRAFQPALVILDLNLPDVSG
CCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCEEEEEECCCCCCCH
YDLCQQMQKETGVYVLMLTSRVSPADKLHGFQLGADDYLTKPFSLPELQARVQAILRRQR
HHHHHHHHHCCCEEEEEEECCCCCHHHHCCEEECCHHHHCCCCCCHHHHHHHHHHHHHHH
MKTEVASAPVLTFASLVIDPETRAVIREQRLINLTALEFDLLYAMARHPGRVWRRAELIQ
HHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EVWDFNHEGDERVVDVHIGQIRKKLETDTSQPELIRTVRGVGYKFEPPAPKEGWGEEKP
HHHCCCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHCCEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRILIIDDDPSICALLQRYLQRQGYSVEVAMTGAEGLQQLRAFQPALVILDLNLPDVSG
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCEEEEEECCCCCCCH
YDLCQQMQKETGVYVLMLTSRVSPADKLHGFQLGADDYLTKPFSLPELQARVQAILRRQR
HHHHHHHHHCCCEEEEEEECCCCCHHHHCCEEECCHHHHCCCCCCHHHHHHHHHHHHHHH
MKTEVASAPVLTFASLVIDPETRAVIREQRLINLTALEFDLLYAMARHPGRVWRRAELIQ
HHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EVWDFNHEGDERVVDVHIGQIRKKLETDTSQPELIRTVRGVGYKFEPPAPKEGWGEEKP
HHHCCCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHCCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]