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The map label for this gene is pilH [H]

Identifier: 86609394

GI number: 86609394

Start: 2029963

End: 2030340

Strand: Reverse

Name: pilH [H]

Synonym: CYB_1938

Alternate gene names: 86609394

Gene position: 2030340-2029963 (Counterclockwise)

Preceding gene: 86609395

Following gene: 86609393

Centisome position: 66.64

GC content: 53.17

Gene sequence:

>378_bases
ATGAGCAAAGTGCTGGTGGTGGATGACAGCCGTACCTACCTGGAGACCATTTCCAGCTTGCTTTCCGAGAACGGTTTGGA
AGTCTCCACAGCAACAGACGGCGTAGAGGCAATGGAGTGCATTCGCCAGCAGAAGCCTGATGTGGTGGTGCTGGATATTG
TCATGCCGCGCATGAACGGCTACGAGGTATGCCGGGAAGTGAAGGGGGATGAAAGTACCAAACACATTCGCATCGTCATG
TGTTCCACCAAAGACCAGACCTTTGATATCGAGTGGGCCAGGCGCAACCAGGCGGATGCCTATGTAACCAAGCCCTTTAA
GCCCCAAGAGCTCCTGGCGACCATCAAACATCAATTGCGGGAGATGAATCGGAAATGA

Upstream 100 bases:

>100_bases
TGGCTGACTTGGAGCCATGGAGCCGGGTGAGGTTAGAAGGCGAAATCTCAGTCAAAGCAGCCCGACGGTTGCGCGGGAGT
GCAAAAGGAGCAAGACGGCG

Downstream 100 bases:

>100_bases
GTCGCGTTTTGGTGGTGGAAGATAGCCAATCCCAGCGGGAGATGATCAGCAAGCTGCTGCAGGAAAACGGCTTCGAGGTG
ATGACTGTGGAAGACGGGGT

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 124

Protein sequence:

>125_residues
MSKVLVVDDSRTYLETISSLLSENGLEVSTATDGVEAMECIRQQKPDVVVLDIVMPRMNGYEVCREVKGDESTKHIRIVM
CSTKDQTFDIEWARRNQADAYVTKPFKPQELLATIKHQLREMNRK

Sequences:

>Translated_125_residues
MSKVLVVDDSRTYLETISSLLSENGLEVSTATDGVEAMECIRQQKPDVVVLDIVMPRMNGYEVCREVKGDESTKHIRIVM
CSTKDQTFDIEWARRNQADAYVTKPFKPQELLATIKHQLREMNRK
>Mature_124_residues
SKVLVVDDSRTYLETISSLLSENGLEVSTATDGVEAMECIRQQKPDVVVLDIVMPRMNGYEVCREVKGDESTKHIRIVMC
STKDQTFDIEWARRNQADAYVTKPFKPQELLATIKHQLREMNRK

Specific function: May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=121, Percent_Identity=30.5785123966942, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1790860, Length=121, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=3e-13,
Organism=Escherichia coli, GI1789809, Length=118, Percent_Identity=29.6610169491525, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1790863, Length=121, Percent_Identity=29.7520661157025, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI1788394, Length=118, Percent_Identity=27.9661016949153, Blast_Score=62, Evalue=9e-12,
Organism=Escherichia coli, GI87082012, Length=119, Percent_Identity=26.0504201680672, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 14349; Mature: 14217

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVLVVDDSRTYLETISSLLSENGLEVSTATDGVEAMECIRQQKPDVVVLDIVMPRMNG
CCCEEEEECCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCH
YEVCREVKGDESTKHIRIVMCSTKDQTFDIEWARRNQADAYVTKPFKPQELLATIKHQLR
HHHHHHCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHH
EMNRK
HHCCC
>Mature Secondary Structure 
SKVLVVDDSRTYLETISSLLSENGLEVSTATDGVEAMECIRQQKPDVVVLDIVMPRMNG
CCEEEEECCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCH
YEVCREVKGDESTKHIRIVMCSTKDQTFDIEWARRNQADAYVTKPFKPQELLATIKHQLR
HHHHHHCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHH
EMNRK
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7908398; 10984043 [H]