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The map label for this gene is pilH [H]

Identifier: 86609393

GI number: 86609393

Start: 2029601

End: 2029966

Strand: Reverse

Name: pilH [H]

Synonym: CYB_1937

Alternate gene names: 86609393

Gene position: 2029966-2029601 (Counterclockwise)

Preceding gene: 86609394

Following gene: 86609392

Centisome position: 66.63

GC content: 56.01

Gene sequence:

>366_bases
ATGAGTCGCGTTTTGGTGGTGGAAGATAGCCAATCCCAGCGGGAGATGATCAGCAAGCTGCTGCAGGAAAACGGCTTCGA
GGTGATGACTGTGGAAGACGGGGTGGAGGCCGTAGAGGCGGTGAAGCAAAACAAACCCGACCTGATCGTGCTGGACATCG
TCATGCCGCGCATGAACGGCTATGAGGTGTGCCGTCTTCTCAAGGCCGACCCTCTCACCCAAAAAACGCCCATCGTCATG
TGTTCTTCCAAGGGCGAAGAATTTGACCGCTACTGGGGGATCCGCCAGGGAGCGGATGCCTACATTGCCAAGCCTTTCCA
GCCCCAGGAACTGGTGGGTACGATTAAGCAATTACTGAGAGGCTGA

Upstream 100 bases:

>100_bases
GGGCCAGGCGCAACCAGGCGGATGCCTATGTAACCAAGCCCTTTAAGCCCCAAGAGCTCCTGGCGACCATCAAACATCAA
TTGCGGGAGATGAATCGGAA

Downstream 100 bases:

>100_bases
GAGCTGCCCCTTCTGCTTCCACGCCTTTCGGTAGGTCCTGAGAACGACTCTGCGTTTTAAGCAGGGAGGGGGGCGGGATC
AACAGTCCACAAGACTATCC

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MSRVLVVEDSQSQREMISKLLQENGFEVMTVEDGVEAVEAVKQNKPDLIVLDIVMPRMNGYEVCRLLKADPLTQKTPIVM
CSSKGEEFDRYWGIRQGADAYIAKPFQPQELVGTIKQLLRG

Sequences:

>Translated_121_residues
MSRVLVVEDSQSQREMISKLLQENGFEVMTVEDGVEAVEAVKQNKPDLIVLDIVMPRMNGYEVCRLLKADPLTQKTPIVM
CSSKGEEFDRYWGIRQGADAYIAKPFQPQELVGTIKQLLRG
>Mature_120_residues
SRVLVVEDSQSQREMISKLLQENGFEVMTVEDGVEAVEAVKQNKPDLIVLDIVMPRMNGYEVCRLLKADPLTQKTPIVMC
SSKGEEFDRYWGIRQGADAYIAKPFQPQELVGTIKQLLRG

Specific function: May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=44.0677966101695, Blast_Score=105, Evalue=8e-25,
Organism=Escherichia coli, GI1790860, Length=117, Percent_Identity=36.7521367521368, Blast_Score=92, Evalue=1e-20,
Organism=Escherichia coli, GI1789809, Length=118, Percent_Identity=37.2881355932203, Blast_Score=91, Evalue=3e-20,
Organism=Escherichia coli, GI1788394, Length=118, Percent_Identity=35.5932203389831, Blast_Score=85, Evalue=1e-18,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=33.8983050847458, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI2367329, Length=120, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=5e-17,
Organism=Escherichia coli, GI87082012, Length=118, Percent_Identity=29.6610169491525, Blast_Score=75, Evalue=9e-16,
Organism=Escherichia coli, GI1786911, Length=120, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1790863, Length=117, Percent_Identity=29.0598290598291, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=110, Percent_Identity=30, Blast_Score=66, Evalue=6e-13,
Organism=Escherichia coli, GI1787375, Length=118, Percent_Identity=28.8135593220339, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI1789149, Length=108, Percent_Identity=31.4814814814815, Blast_Score=62, Evalue=9e-12,
Organism=Escherichia coli, GI1787229, Length=118, Percent_Identity=28.8135593220339, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=27.5, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1789402, Length=118, Percent_Identity=28.8135593220339, Blast_Score=61, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=117, Percent_Identity=28.2051282051282, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 13687; Mature: 13556

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVLVVEDSQSQREMISKLLQENGFEVMTVEDGVEAVEAVKQNKPDLIVLDIVMPRMNG
CCCEEEEECCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCCCCCEEEEEEECCCCCH
YEVCRLLKADPLTQKTPIVMCSSKGEEFDRYWGIRQGADAYIAKPFQPQELVGTIKQLLR
HHHHHHHHCCCCCCCCCEEEECCCCCHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHC
G
C
>Mature Secondary Structure 
SRVLVVEDSQSQREMISKLLQENGFEVMTVEDGVEAVEAVKQNKPDLIVLDIVMPRMNG
CCEEEEECCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCCCCCEEEEEEECCCCCH
YEVCRLLKADPLTQKTPIVMCSSKGEEFDRYWGIRQGADAYIAKPFQPQELVGTIKQLLR
HHHHHHHHCCCCCCCCCEEEECCCCCHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7908398; 10984043 [H]