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The map label for this gene is coaX

Identifier: 86608977

GI number: 86608977

Start: 1582707

End: 1583471

Strand: Direct

Name: coaX

Synonym: CYB_1510

Alternate gene names: 86608977

Gene position: 1582707-1583471 (Clockwise)

Preceding gene: 86608976

Following gene: 86608978

Centisome position: 51.95

GC content: 66.41

Gene sequence:

>765_bases
ATGAGTTTTGAGGAGGGGGCAGATCTCAACGCTTCGCACTGTTGTCGTGAGTGGCTGGCAGCCGTGCTGGGCAACACTCA
CGTGCGCTGGGGTTGGTTTGTGGAGGAGACCCTGGTGAAGGTGGAGCGGTTTCCTGCTCACCAGCCCTTGTCCTGGCCGC
AGCAGACAGAGCTGTGGCTGGCTCCTGTGGGCTCTGCCCCCCTGCCGCCAGCATCGCCCTGGGTGCATCAGTTGGAGCTG
TCGCAGGTGCCGCTGCGGGATCCCTACCCGGGGTTGGGGCTGGATCGGGCCTTGGCCCTGTGGGCTGCCGGGATCCACTA
CGGCTGGCCCTGTTTGGTCATCGACGCGGGTACTGCCCTGACCCTCACAGGAGCTGACTCTGAAGGATCCCTGGTGGGAG
GGGCCATCTTGCCCGGCCTGGGGTTGCAGGCGCAGGCGTTGGCTGATCACACAGCCCTGCTGCCCAAAGTGCAGTGGGAT
CCGCAGGATCCCTTGCCCCCTCGCTGGGCCAACGACACCGTGGCTGCCATCCGCAGCGGCATCCTCCACACCCTCTTGGC
TGGCTTGCGCGAGTTCATTGCCGACTGGCGTCGCCGCTTTCCCCAAGGCCCCCTGCTGCTGACCGGCGGGGATGGGAAGT
GGCTCCACCCTCACTTGGGCCCGCTTGACCCAGAGCTGCGCTGGGATCCCCACCTGGTGTTGCGGGGAATTGCCGGCTGC
CGCCAGCTGCACCGCACTGCCCGCCACTCCCCTAGTGCAGAATAG

Upstream 100 bases:

>100_bases
GCTTTGACGACAGAATGGCAGCTTGCTACCGCTAAGAGGTTGGCCGGGATCCCTGTCGACCAGCCGGTGGAGCTGTTTCG
CGTGGAGGCAGAGCTGTTGC

Downstream 100 bases:

>100_bases
AAAACAGTCTCTCCCAGCCGCCTGCGAGTAACGGCTTCTTGCTTGGGGATCCCATGGCCAACGGCAACTCCTTCGGTGTC
CTGTTTTGCGTGACCACCTA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSFEEGADLNASHCCREWLAAVLGNTHVRWGWFVEETLVKVERFPAHQPLSWPQQTELWLAPVGSAPLPPASPWVHQLEL
SQVPLRDPYPGLGLDRALALWAAGIHYGWPCLVIDAGTALTLTGADSEGSLVGGAILPGLGLQAQALADHTALLPKVQWD
PQDPLPPRWANDTVAAIRSGILHTLLAGLREFIADWRRRFPQGPLLLTGGDGKWLHPHLGPLDPELRWDPHLVLRGIAGC
RQLHRTARHSPSAE

Sequences:

>Translated_254_residues
MSFEEGADLNASHCCREWLAAVLGNTHVRWGWFVEETLVKVERFPAHQPLSWPQQTELWLAPVGSAPLPPASPWVHQLEL
SQVPLRDPYPGLGLDRALALWAAGIHYGWPCLVIDAGTALTLTGADSEGSLVGGAILPGLGLQAQALADHTALLPKVQWD
PQDPLPPRWANDTVAAIRSGILHTLLAGLREFIADWRRRFPQGPLLLTGGDGKWLHPHLGPLDPELRWDPHLVLRGIAGC
RQLHRTARHSPSAE
>Mature_253_residues
SFEEGADLNASHCCREWLAAVLGNTHVRWGWFVEETLVKVERFPAHQPLSWPQQTELWLAPVGSAPLPPASPWVHQLELS
QVPLRDPYPGLGLDRALALWAAGIHYGWPCLVIDAGTALTLTGADSEGSLVGGAILPGLGLQAQALADHTALLPKVQWDP
QDPLPPRWANDTVAAIRSGILHTLLAGLREFIADWRRRFPQGPLLLTGGDGKWLHPHLGPLDPELRWDPHLVLRGIAGCR
QLHRTARHSPSAE

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_SYNJB (Q2JLD5)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_477739.1
- ProteinModelPortal:   Q2JLD5
- SMR:   Q2JLD5
- STRING:   Q2JLD5
- GeneID:   3901509
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_1510
- TIGR:   CYB_1510
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   HWGYFQG
- ProtClustDB:   PRK13331
- BioCyc:   SSP321332:CYB_1510-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27836; Mature: 27705

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: ACT_SITE 95-95 BINDING 89-89 BINDING 118-118 BINDING 173-173

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFEEGADLNASHCCREWLAAVLGNTHVRWGWFVEETLVKVERFPAHQPLSWPQQTELWL
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
APVGSAPLPPASPWVHQLELSQVPLRDPYPGLGLDRALALWAAGIHYGWPCLVIDAGTAL
EECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCEE
TLTGADSEGSLVGGAILPGLGLQAQALADHTALLPKVQWDPQDPLPPRWANDTVAAIRSG
EEECCCCCCCEECHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
ILHTLLAGLREFIADWRRRFPQGPLLLTGGDGKWLHPHLGPLDPELRWDPHLVLRGIAGC
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEECCCCCCCCCCCCCCHHHHHHHHHHH
RQLHRTARHSPSAE
HHHHHHHCCCCCCC
>Mature Secondary Structure 
SFEEGADLNASHCCREWLAAVLGNTHVRWGWFVEETLVKVERFPAHQPLSWPQQTELWL
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
APVGSAPLPPASPWVHQLELSQVPLRDPYPGLGLDRALALWAAGIHYGWPCLVIDAGTAL
EECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCEE
TLTGADSEGSLVGGAILPGLGLQAQALADHTALLPKVQWDPQDPLPPRWANDTVAAIRSG
EEECCCCCCCEECHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
ILHTLLAGLREFIADWRRRFPQGPLLLTGGDGKWLHPHLGPLDPELRWDPHLVLRGIAGC
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEECCCCCCCCCCCCCCHHHHHHHHHHH
RQLHRTARHSPSAE
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA