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The map label for this gene is aroC [H]

Identifier: 86608978

GI number: 86608978

Start: 1583525

End: 1584661

Strand: Direct

Name: aroC [H]

Synonym: CYB_1511

Alternate gene names: 86608978

Gene position: 1583525-1584661 (Clockwise)

Preceding gene: 86608977

Following gene: 86608979

Centisome position: 51.98

GC content: 66.49

Gene sequence:

>1137_bases
ATGGCCAACGGCAACTCCTTCGGTGTCCTGTTTTGCGTGACCACCTATGGCGAGTCCCACGGGGGGGCGGTGGGGGTGGT
GGTGGATGGCTGCCCGCCGCGGCTGCCCTTGAGCGAGGCCGACATTCAGGCAGAGCTGGATCGGCGGCGTCCTGGCCAGA
GCCCCATCACGACGCCCCGCCAGGAAGCGGATCGCTGCCAGATCCTCTCCGGGGTTTTTCAGGGCTTTACGCTGGGCACC
CCCATCCACATCCTGGTGCGCAACCAAGATGCCCGCCCCCAGGACTACCAGGAGATGGCCACCACCTTCCGCCCTTCCCA
TGCCGATGCCACCTACCAGGCCAAGTACGGCATCCGCAACTGGCAGGGGGGCGGACGGGCCTCAGCGCGAGAAACCATTG
GCCGGGTGGCTGCCGGGGCCATTGCCAAGAAGATCCTGCGCCTAGCGGCAGGGGTGGAGATCCTGGCCTACGTGCAGCGG
GTAAAAGACGTGGAAGCCCAGGTGGATCCCAGCTCGGTAACTGCAGAGCAGGTGGAGGCCAACATCGTCCGCTGCCCCGA
TCCCCAAGCGGCGGCGGCCATGATCCAAAAAATTGAGGAGGCGGCGCGGGAAGGGGATTCGCTGGGGGGAGTGGTGGAGT
GTGTAGCCCGCCGGGTGCCGCGCGGGCTGGGATCCCCGGTGTTTGACAAGCTGGAGGCCGACTTGGCCAAGGCGGTGATG
TCCCTGCCAGCCAGCAAGGGGTTTGAGATTGGCTCGGGGTTTGCCGGCACCTACCTGACGGGCAAGCAGCACAACGACGA
GTTTTACATGACCCCCGGCGGCTGGCGCACCCGCAGCAACCGCTCCGGCGGCATCCAGGGGGGCATCAGCAACGGCGAAG
ACATCGTCCTGCGGGTAGCCTTTAAGCCCACTGCCACCATTCGCCAGCCTCAAAACACCGTCACCCTCAATGGGCAAGAG
ACGGTTTTGGCGGCGCGGGGACGCCACGATCCCTGTGTCTTGCCGCGGGCAGTGCCGATGGTGGAGGCGATGGTGGCCCT
GGTCCTCTGCGACCATCTGCTGCGCCACCACGCCCAGTGCGGATCCCTGGTCTTGTCGGAGGTGCCCCTCCCTGTCGCCG
CTGCTCCCCAGGCCTAG

Upstream 100 bases:

>100_bases
GCCGCCAGCTGCACCGCACTGCCCGCCACTCCCCTAGTGCAGAATAGAAAACAGTCTCTCCCAGCCGCCTGCGAGTAACG
GCTTCTTGCTTGGGGATCCC

Downstream 100 bases:

>100_bases
GAGTCCCCGGCTATGGCCAAGGCCAAAACCGTCTGGGAGTGCAGCCAGTGCGGCGAGCGCTATGCCAAGTTTTTGGGCCG
CTGCGACCATTGCGGCGCCT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MANGNSFGVLFCVTTYGESHGGAVGVVVDGCPPRLPLSEADIQAELDRRRPGQSPITTPRQEADRCQILSGVFQGFTLGT
PIHILVRNQDARPQDYQEMATTFRPSHADATYQAKYGIRNWQGGGRASARETIGRVAAGAIAKKILRLAAGVEILAYVQR
VKDVEAQVDPSSVTAEQVEANIVRCPDPQAAAAMIQKIEEAAREGDSLGGVVECVARRVPRGLGSPVFDKLEADLAKAVM
SLPASKGFEIGSGFAGTYLTGKQHNDEFYMTPGGWRTRSNRSGGIQGGISNGEDIVLRVAFKPTATIRQPQNTVTLNGQE
TVLAARGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQCGSLVLSEVPLPVAAAPQA

Sequences:

>Translated_378_residues
MANGNSFGVLFCVTTYGESHGGAVGVVVDGCPPRLPLSEADIQAELDRRRPGQSPITTPRQEADRCQILSGVFQGFTLGT
PIHILVRNQDARPQDYQEMATTFRPSHADATYQAKYGIRNWQGGGRASARETIGRVAAGAIAKKILRLAAGVEILAYVQR
VKDVEAQVDPSSVTAEQVEANIVRCPDPQAAAAMIQKIEEAAREGDSLGGVVECVARRVPRGLGSPVFDKLEADLAKAVM
SLPASKGFEIGSGFAGTYLTGKQHNDEFYMTPGGWRTRSNRSGGIQGGISNGEDIVLRVAFKPTATIRQPQNTVTLNGQE
TVLAARGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQCGSLVLSEVPLPVAAAPQA
>Mature_377_residues
ANGNSFGVLFCVTTYGESHGGAVGVVVDGCPPRLPLSEADIQAELDRRRPGQSPITTPRQEADRCQILSGVFQGFTLGTP
IHILVRNQDARPQDYQEMATTFRPSHADATYQAKYGIRNWQGGGRASARETIGRVAAGAIAKKILRLAAGVEILAYVQRV
KDVEAQVDPSSVTAEQVEANIVRCPDPQAAAAMIQKIEEAAREGDSLGGVVECVARRVPRGLGSPVFDKLEADLAKAVMS
LPASKGFEIGSGFAGTYLTGKQHNDEFYMTPGGWRTRSNRSGGIQGGISNGEDIVLRVAFKPTATIRQPQNTVTLNGQET
VLAARGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQCGSLVLSEVPLPVAAAPQA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=366, Percent_Identity=51.3661202185792, Blast_Score=335, Evalue=2e-93,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=54.7683923705722, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 40291; Mature: 40160

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANGNSFGVLFCVTTYGESHGGAVGVVVDGCPPRLPLSEADIQAELDRRRPGQSPITTPR
CCCCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCH
QEADRCQILSGVFQGFTLGTPIHILVRNQDARPQDYQEMATTFRPSHADATYQAKYGIRN
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCC
WQGGGRASARETIGRVAAGAIAKKILRLAAGVEILAYVQRVKDVEAQVDPSSVTAEQVEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
NIVRCPDPQAAAAMIQKIEEAAREGDSLGGVVECVARRVPRGLGSPVFDKLEADLAKAVM
CEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SLPASKGFEIGSGFAGTYLTGKQHNDEFYMTPGGWRTRSNRSGGIQGGISNGEDIVLRVA
HCCCCCCCCCCCCCCCCEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
FKPTATIRQPQNTVTLNGQETVLAARGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQC
ECCCCCCCCCCCEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GSLVLSEVPLPVAAAPQA
HHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ANGNSFGVLFCVTTYGESHGGAVGVVVDGCPPRLPLSEADIQAELDRRRPGQSPITTPR
CCCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCH
QEADRCQILSGVFQGFTLGTPIHILVRNQDARPQDYQEMATTFRPSHADATYQAKYGIRN
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCC
WQGGGRASARETIGRVAAGAIAKKILRLAAGVEILAYVQRVKDVEAQVDPSSVTAEQVEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
NIVRCPDPQAAAAMIQKIEEAAREGDSLGGVVECVARRVPRGLGSPVFDKLEADLAKAVM
CEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SLPASKGFEIGSGFAGTYLTGKQHNDEFYMTPGGWRTRSNRSGGIQGGISNGEDIVLRVA
HCCCCCCCCCCCCCCCCEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
FKPTATIRQPQNTVTLNGQETVLAARGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQC
ECCCCCCCCCCCEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GSLVLSEVPLPVAAAPQA
HHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA