BacMap

Definition	Synechococcus sp. JA-2-3B'a(2-13), complete genome.
Accession	NC_007776
Length	3,046,682

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The map label for this gene is ppiB [H]

Identifier: 86608940

GI number: 86608940

Start: 1549452

End: 1549931

Strand: Reverse

Name: ppiB [H]

Synonym: CYB_1473

Alternate gene names: 86608940

Gene position: 1549931-1549452 (Counterclockwise)

Preceding gene: 86608941

Following gene: 86608939

Centisome position: 50.87

GC content: 59.38

Gene sequence:

>480_bases
ATGGTGATCGACCCGGCCAAGTCCTACACGGCCACGATGGAGACCACCGCCGGCACAATGGTTCTGGAGCTGTTCCCGCA
AGAAGCTCCCCTCGCCGTCAACAATTTCGTCTTTTTGGCCAACGACCACTTCTACGATGGTGTCATCTTTCACCGCGTGA
TTCGGGGCTTCATGATCCAAGGTGGGGATCCCACGGGTACAGGGCGGGGTGGGCCGGGGTACCGCTTTCCCGATGAGCCG
GTGCAACGTCCCTACAGCCGTGGCACTTTGGCGATGGCCAACGCCGGCCCCAACACCAACGGCAGCCAGTTCTTCATCAT
GCATGCCGACTACCCGCTGCCGCCCAACTACACGATCTTCGGGCAATTGATCGAGGGAGAGGATGTGTTGGATAAAATTG
CAACGGCTCCCACGGGCCCCCAGGATCGCCCGCTGAATCCAGTGGAGATCCAGTCCGTTCGTATCTCGGAATCCAATTAG

Upstream 100 bases:

>100_bases
GAGTGCTCTCCCTGTCTTGGCCCGCCCGCATTCTTCTCGCGATTTGCTCCTGGCACAACACTTGGGCAAACCCGTGAAAA
CCTACAACAATCCCCCCCCG

Downstream 100 bases:

>100_bases
GTTGGGCCACTCCGGTGGAACAGTTTGGTTAAATTAACTTGGCCTCTGGCCCCATTTTTGCAACTTGCCCTCAGGGGGAC
TCAGGTATGGAGTTCGCTAG

Product: peptidylprolyl cis-trans isomerase, cyclophilin-type

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MVIDPAKSYTATMETTAGTMVLELFPQEAPLAVNNFVFLANDHFYDGVIFHRVIRGFMIQGGDPTGTGRGGPGYRFPDEP
VQRPYSRGTLAMANAGPNTNGSQFFIMHADYPLPPNYTIFGQLIEGEDVLDKIATAPTGPQDRPLNPVEIQSVRISESN

Sequences:

>Translated_159_residues
MVIDPAKSYTATMETTAGTMVLELFPQEAPLAVNNFVFLANDHFYDGVIFHRVIRGFMIQGGDPTGTGRGGPGYRFPDEP
VQRPYSRGTLAMANAGPNTNGSQFFIMHADYPLPPNYTIFGQLIEGEDVLDKIATAPTGPQDRPLNPVEIQSVRISESN
>Mature_159_residues
MVIDPAKSYTATMETTAGTMVLELFPQEAPLAVNNFVFLANDHFYDGVIFHRVIRGFMIQGGDPTGTGRGGPGYRFPDEP
VQRPYSRGTLAMANAGPNTNGSQFFIMHADYPLPPNYTIFGQLIEGEDVLDKIATAPTGPQDRPLNPVEIQSVRISESN

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI19557636, Length=153, Percent_Identity=44.4444444444444, Blast_Score=133, Evalue=8e-32,
Organism=Homo sapiens, GI7706339, Length=144, Percent_Identity=47.9166666666667, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI24308049, Length=158, Percent_Identity=43.0379746835443, Blast_Score=118, Evalue=3e-27,
Organism=Homo sapiens, GI64276486, Length=152, Percent_Identity=44.078947368421, Blast_Score=114, Evalue=5e-26,
Organism=Homo sapiens, GI4758950, Length=142, Percent_Identity=43.6619718309859, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI4505991, Length=146, Percent_Identity=43.8356164383562, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI5454154, Length=152, Percent_Identity=41.4473684210526, Blast_Score=94, Evalue=7e-20,
Organism=Homo sapiens, GI20911035, Length=136, Percent_Identity=38.9705882352941, Blast_Score=91, Evalue=3e-19,
Organism=Homo sapiens, GI22547212, Length=150, Percent_Identity=44, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI7657473, Length=150, Percent_Identity=44, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI42560244, Length=153, Percent_Identity=37.2549019607843, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI22547215, Length=150, Percent_Identity=44, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI5031987, Length=128, Percent_Identity=45.3125, Blast_Score=85, Evalue=3e-17,
Organism=Homo sapiens, GI256017253, Length=123, Percent_Identity=41.4634146341463, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI221139811, Length=123, Percent_Identity=41.4634146341463, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI256017251, Length=123, Percent_Identity=41.4634146341463, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI4826932, Length=126, Percent_Identity=42.0634920634921, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI10863927, Length=125, Percent_Identity=41.6, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI303305009, Length=131, Percent_Identity=40.4580152671756, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI27735045, Length=149, Percent_Identity=36.241610738255, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI178057341, Length=123, Percent_Identity=40.650406504065, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI6631100, Length=150, Percent_Identity=36, Blast_Score=78, Evalue=3e-15,
Organism=Homo sapiens, GI209417936, Length=123, Percent_Identity=40.650406504065, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI30102944, Length=123, Percent_Identity=40.650406504065, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI219842199, Length=123, Percent_Identity=40.650406504065, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI45439316, Length=127, Percent_Identity=40.1574803149606, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI310129267, Length=125, Percent_Identity=38.4, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI310120620, Length=125, Percent_Identity=38.4, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI5174637, Length=127, Percent_Identity=40.1574803149606, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI310127646, Length=126, Percent_Identity=40.4761904761905, Blast_Score=74, Evalue=7e-14,
Organism=Homo sapiens, GI310114371, Length=126, Percent_Identity=40.4761904761905, Blast_Score=74, Evalue=7e-14,
Organism=Homo sapiens, GI310119221, Length=126, Percent_Identity=40.4761904761905, Blast_Score=74, Evalue=7e-14,
Organism=Homo sapiens, GI14277126, Length=96, Percent_Identity=44.7916666666667, Blast_Score=73, Evalue=8e-14,
Organism=Homo sapiens, GI169163387, Length=125, Percent_Identity=38.4, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI169164185, Length=134, Percent_Identity=38.0597014925373, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI169163623, Length=134, Percent_Identity=38.0597014925373, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI310110104, Length=125, Percent_Identity=37.6, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1789763, Length=160, Percent_Identity=40, Blast_Score=93, Evalue=7e-21,
Organism=Escherichia coli, GI1786736, Length=169, Percent_Identity=36.094674556213, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17539496, Length=153, Percent_Identity=47.0588235294118, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71980594, Length=152, Percent_Identity=44.078947368421, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71980590, Length=142, Percent_Identity=44.3661971830986, Blast_Score=119, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI71997782, Length=164, Percent_Identity=39.6341463414634, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17551282, Length=152, Percent_Identity=42.7631578947368, Blast_Score=105, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17551284, Length=152, Percent_Identity=42.7631578947368, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17552780, Length=142, Percent_Identity=47.1830985915493, Blast_Score=103, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17532641, Length=150, Percent_Identity=40.6666666666667, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17506307, Length=144, Percent_Identity=44.4444444444444, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17506311, Length=154, Percent_Identity=40.2597402597403, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32563659, Length=153, Percent_Identity=34.640522875817, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17552784, Length=157, Percent_Identity=36.3057324840764, Blast_Score=90, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17532643, Length=157, Percent_Identity=38.8535031847134, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17559074, Length=135, Percent_Identity=39.2592592592593, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17566266, Length=132, Percent_Identity=40.1515151515151, Blast_Score=86, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17565860, Length=136, Percent_Identity=41.9117647058824, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17539498, Length=143, Percent_Identity=39.1608391608392, Blast_Score=83, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17552782, Length=147, Percent_Identity=38.7755102040816, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321848, Length=148, Percent_Identity=39.8648648648649, Blast_Score=93, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320359, Length=133, Percent_Identity=42.8571428571429, Blast_Score=89, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323562, Length=133, Percent_Identity=41.3533834586466, Blast_Score=83, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320510, Length=143, Percent_Identity=39.8601398601399, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323246, Length=155, Percent_Identity=34.8387096774194, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322492, Length=199, Percent_Identity=30.1507537688442, Blast_Score=65, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17986117, Length=162, Percent_Identity=43.2098765432099, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI19922376, Length=149, Percent_Identity=43.6241610738255, Blast_Score=124, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24652460, Length=155, Percent_Identity=40, Blast_Score=115, Evalue=9e-27,
Organism=Drosophila melanogaster, GI20130249, Length=143, Percent_Identity=42.6573426573427, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19922912, Length=154, Percent_Identity=45.4545454545455, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357249, Length=160, Percent_Identity=37.5, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI45549139, Length=127, Percent_Identity=44.0944881889764, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24586038, Length=157, Percent_Identity=38.2165605095541, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24650807, Length=150, Percent_Identity=38.6666666666667, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21355677, Length=162, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24664125, Length=134, Percent_Identity=42.5373134328358, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357783, Length=134, Percent_Identity=42.5373134328358, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17647301, Length=127, Percent_Identity=42.5196850393701, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17136360, Length=149, Percent_Identity=36.9127516778523, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17363; Mature: 17363

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIDPAKSYTATMETTAGTMVLELFPQEAPLAVNNFVFLANDHFYDGVIFHRVIRGFMIQ
CCCCCCCCCEEEEECCCCEEEEEECCCCCCEEECCEEEEECCCCCCHHHHHHHHHHHEEE
GGDPTGTGRGGPGYRFPDEPVQRPYSRGTLAMANAGPNTNGSQFFIMHADYPLPPNYTIF
CCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCEEEE
GQLIEGEDVLDKIATAPTGPQDRPLNPVEIQSVRISESN
EEEECCHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MVIDPAKSYTATMETTAGTMVLELFPQEAPLAVNNFVFLANDHFYDGVIFHRVIRGFMIQ
CCCCCCCCCEEEEECCCCEEEEEECCCCCCEEECCEEEEECCCCCCHHHHHHHHHHHEEE
GGDPTGTGRGGPGYRFPDEPVQRPYSRGTLAMANAGPNTNGSQFFIMHADYPLPPNYTIF
CCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCEEEE
GQLIEGEDVLDKIATAPTGPQDRPLNPVEIQSVRISESN
EEEECCHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9317025; 9665876 [H]