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The map label for this gene is coaE

Identifier: 86608781

GI number: 86608781

Start: 1369405

End: 1370121

Strand: Reverse

Name: coaE

Synonym: CYB_1306

Alternate gene names: 86608781

Gene position: 1370121-1369405 (Counterclockwise)

Preceding gene: 86608782

Following gene: 86608780

Centisome position: 44.97

GC content: 61.51

Gene sequence:

>717_bases
ATGAGGATCATCGGCCTGACGGGCGGAGTGGGCACGGGCAAATCCACGGTGGCCCGCATCCTGGAGCAGCACGGGATCCC
AGTAGCCGATGCAGATCAAATGGCCCGCCAGGCCTTGGCGGTGGGATCCCCCATTCGCGAGCGGGTACTGGAACGCTATG
GGAAGGTCATCCAAACACCCTCCGGGGATCTGGATCGCCGGCGGTTGGGCCAGATCGTGTTTGCAGATGCCGCTGAGCGG
GCTTGGCTAGAGGCCCAAATCCACCCTTTCGTTAGAGCTCAACTGCAAGATTTTCTGTCCGCGTTGGCGGAGCAGAGCTC
TAAAGTCCATGGGGTGCCGCTTGAGGAAGAGCCTGCCTCCCAAAAGCGTAGCGGGGTAGGATTTTCTTCTGGGCAGGGAT
CCCAAACCGTTTGTCTGATGATCCCGTTGCTGTTTGAAGCCCACATGGAAAATTGGGCCAGCGAGATTTGGGTGGTGACT
TGCACCCCAGAGCAGCAGCGGCAACGCCTTGCCCGCCGGGATCCCCTGACGCCGGAAGAAATCGAAGCTCGCATTGCCAG
CCAGTGGCCTTTGGCGGAAAAAGTGCGCCGTGCAGACGTGGTGCTGGACAACTCCGGATCCCTGGCCGAGCTGGAAGCCC
AGGTGAAGCAAGCTTTGGCGTCGGCGGGCCAGAGGCCATTTGCCTCACCCCCGCGGGCCGGATACAGTGACGGGTAG

Upstream 100 bases:

>100_bases
TGCCCGCTTCTGCAGAGCACCGTTCTAACGACTCCGTCCGAGTAGCGCAAACGGCAATGGCCGCACCAGCGGCCTCTTCT
TGACTATGGCCTACAGCTCG

Downstream 100 bases:

>100_bases
GGTCTGGTGGGACGGATCCCTTGGTATCCATGTACGGATGGGTTGAGGGAGAAACGATGCAGGAAGCAGGTTGCATCGGC
AAGACGGAGTTTGCCCAAGC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MRIIGLTGGVGTGKSTVARILEQHGIPVADADQMARQALAVGSPIRERVLERYGKVIQTPSGDLDRRRLGQIVFADAAER
AWLEAQIHPFVRAQLQDFLSALAEQSSKVHGVPLEEEPASQKRSGVGFSSGQGSQTVCLMIPLLFEAHMENWASEIWVVT
CTPEQQRQRLARRDPLTPEEIEARIASQWPLAEKVRRADVVLDNSGSLAELEAQVKQALASAGQRPFASPPRAGYSDG

Sequences:

>Translated_238_residues
MRIIGLTGGVGTGKSTVARILEQHGIPVADADQMARQALAVGSPIRERVLERYGKVIQTPSGDLDRRRLGQIVFADAAER
AWLEAQIHPFVRAQLQDFLSALAEQSSKVHGVPLEEEPASQKRSGVGFSSGQGSQTVCLMIPLLFEAHMENWASEIWVVT
CTPEQQRQRLARRDPLTPEEIEARIASQWPLAEKVRRADVVLDNSGSLAELEAQVKQALASAGQRPFASPPRAGYSDG
>Mature_238_residues
MRIIGLTGGVGTGKSTVARILEQHGIPVADADQMARQALAVGSPIRERVLERYGKVIQTPSGDLDRRRLGQIVFADAAER
AWLEAQIHPFVRAQLQDFLSALAEQSSKVHGVPLEEEPASQKRSGVGFSSGQGSQTVCLMIPLLFEAHMENWASEIWVVT
CTPEQQRQRLARRDPLTPEEIEARIASQWPLAEKVRRADVVLDNSGSLAELEAQVKQALASAGQRPFASPPRAGYSDG

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=216, Percent_Identity=33.7962962962963, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI191252795, Length=216, Percent_Identity=33.7962962962963, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI110227607, Length=225, Percent_Identity=24.8888888888889, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI110227605, Length=225, Percent_Identity=24.8888888888889, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI110227603, Length=225, Percent_Identity=24.8888888888889, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI110227601, Length=225, Percent_Identity=24.8888888888889, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI205277394, Length=225, Percent_Identity=24.8888888888889, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786292, Length=205, Percent_Identity=30.7317073170732, Blast_Score=100, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17554944, Length=223, Percent_Identity=31.8385650224215, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24644728, Length=214, Percent_Identity=31.3084112149533, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24658602, Length=200, Percent_Identity=29, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_SYNJB (Q2JLX1)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_477543.1
- ProteinModelPortal:   Q2JLX1
- SMR:   Q2JLX1
- STRING:   Q2JLX1
- GeneID:   3901040
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_1306
- TIGR:   CYB_1306
- eggNOG:   COG0237
- HOGENOM:   HBG650290
- OMA:   ARPGMTE
- PhylomeDB:   Q2JLX1
- ProtClustDB:   PRK14730
- BioCyc:   SSP321332:CYB_1306-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 25968; Mature: 25968

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS51219 DPCK; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIGLTGGVGTGKSTVARILEQHGIPVADADQMARQALAVGSPIRERVLERYGKVIQTP
CEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
SGDLDRRRLGQIVFADAAERAWLEAQIHPFVRAQLQDFLSALAEQSSKVHGVPLEEEPAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
QKRSGVGFSSGQGSQTVCLMIPLLFEAHMENWASEIWVVTCTPEQQRQRLARRDPLTPEE
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHCCCCCHHH
IEARIASQWPLAEKVRRADVVLDNSGSLAELEAQVKQALASAGQRPFASPPRAGYSDG
HHHHHHHCCCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRIIGLTGGVGTGKSTVARILEQHGIPVADADQMARQALAVGSPIRERVLERYGKVIQTP
CEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
SGDLDRRRLGQIVFADAAERAWLEAQIHPFVRAQLQDFLSALAEQSSKVHGVPLEEEPAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
QKRSGVGFSSGQGSQTVCLMIPLLFEAHMENWASEIWVVTCTPEQQRQRLARRDPLTPEE
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHCCCCCHHH
IEARIASQWPLAEKVRRADVVLDNSGSLAELEAQVKQALASAGQRPFASPPRAGYSDG
HHHHHHHCCCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA