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The map label for this gene is mraY

Identifier: 86608624

GI number: 86608624

Start: 1184835

End: 1185857

Strand: Direct

Name: mraY

Synonym: CYB_1146

Alternate gene names: 86608624

Gene position: 1184835-1185857 (Clockwise)

Preceding gene: 86608623

Following gene: 86608625

Centisome position: 38.89

GC content: 64.13

Gene sequence:

>1023_bases
ATGGCGCTCTCGCTGGGGCTGGGTTTAGCCCTCTCGGCCCTTGTGATCGGGATCCGCCCCCAGGTGGTCGTTCCTTTTGG
ATTGAGCGCGTTGGGTTCGGCCCTGCTGGGATCCCTGCTCATCCCTGGGTTGCGGCGCTGGAAGGCGGGGCAAGTGATCC
GCCAGGAGGGGCCCCAATCCCACCAGAAAAAAGCAGGCACACCCACCATGGGCGGGATCAGCTTTTTGCCCGTGGGGCTA
CTGGTGGCCGGGATCTGGAGCGGCTGGGATCCCCATTGGCTGGCCGTCGCGCTGCTCACGCTGGCCTACAGCTTTGTCGG
CTGGCTGGACGATTGGCTGGTGATCCGACAGCAATCCAACAAGGGGTTGTCTCCCCAACACAAGCTGTTGCTCCAGGTGG
GAGTTGCCCTTGGGTTTTGTGTCTACCTGGCCTGGCAGGGGATCCCGACCAGTCTGACCTTGCCGGGGATAGGCACCCTC
TCTCTGGGCTGGCTGTTCTGGCCCTTGGCCCTGTTTGTGTTGGTGGGCACCAATAATGCCGTAAACCTCACCGATGGTAT
GGACGGCTTGGCGGCAGGGGTGGTGGCCATCCTGCTGATTGGGCTGGGGCTCCTTCACAGGGATCCAGAGCTATCGGTGT
TGGCTTTCACACTGAGCGGTGCCTGCTTGGGGTTCCTGGTTCACAACCACCACCGGGCGCGGCTGTTCATGGGCGATACC
GGATCCCTGGGGTTGGGGGGCGCTCTGGCCGGGTTGGCGCTGCTGGGGGATCAGCTCTGGGCCTTGGCCCTGATGGGGGG
CGTGCTGGTGGCCGAGGCGCTGTCGGTGATGCTGCAGGTGGGCTACTTCCAATACACCAAACGCAAAACCGGCACAGGCC
AACGGCTGTTGCGCATGTCGCCCTTGCACCACCATCTGGAGCTGGGGGGCTGGTCGGAGGTGCAGGTGGTGGGATCCTTC
TACGGGGTAACGGCGCTGCTGGTGGGGCTGGGCTGGGCCTGGTGGCACTGGACCGGAATGTGA

Upstream 100 bases:

>100_bases
AGTTTTTGAGGGTTTGGAGGTTGAGAGTGTGAGGGGTTCAGAAAGGGTGGATGCGGATACCCTTCCCGATCTGGAGGTGG
AAGAAACAGAGTGGGGCGGG

Downstream 100 bases:

>100_bases
GTTCGAGCTGGGGATCCACCGGGATTCCAATGGGGGCCTGACCTCAAACGGGTTGTTCGGCGTGGGAAATGGCCACCGGC
AGATCGGCCCCCACCCGCTA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MALSLGLGLALSALVIGIRPQVVVPFGLSALGSALLGSLLIPGLRRWKAGQVIRQEGPQSHQKKAGTPTMGGISFLPVGL
LVAGIWSGWDPHWLAVALLTLAYSFVGWLDDWLVIRQQSNKGLSPQHKLLLQVGVALGFCVYLAWQGIPTSLTLPGIGTL
SLGWLFWPLALFVLVGTNNAVNLTDGMDGLAAGVVAILLIGLGLLHRDPELSVLAFTLSGACLGFLVHNHHRARLFMGDT
GSLGLGGALAGLALLGDQLWALALMGGVLVAEALSVMLQVGYFQYTKRKTGTGQRLLRMSPLHHHLELGGWSEVQVVGSF
YGVTALLVGLGWAWWHWTGM

Sequences:

>Translated_340_residues
MALSLGLGLALSALVIGIRPQVVVPFGLSALGSALLGSLLIPGLRRWKAGQVIRQEGPQSHQKKAGTPTMGGISFLPVGL
LVAGIWSGWDPHWLAVALLTLAYSFVGWLDDWLVIRQQSNKGLSPQHKLLLQVGVALGFCVYLAWQGIPTSLTLPGIGTL
SLGWLFWPLALFVLVGTNNAVNLTDGMDGLAAGVVAILLIGLGLLHRDPELSVLAFTLSGACLGFLVHNHHRARLFMGDT
GSLGLGGALAGLALLGDQLWALALMGGVLVAEALSVMLQVGYFQYTKRKTGTGQRLLRMSPLHHHLELGGWSEVQVVGSF
YGVTALLVGLGWAWWHWTGM
>Mature_339_residues
ALSLGLGLALSALVIGIRPQVVVPFGLSALGSALLGSLLIPGLRRWKAGQVIRQEGPQSHQKKAGTPTMGGISFLPVGLL
VAGIWSGWDPHWLAVALLTLAYSFVGWLDDWLVIRQQSNKGLSPQHKLLLQVGVALGFCVYLAWQGIPTSLTLPGIGTLS
LGWLFWPLALFVLVGTNNAVNLTDGMDGLAAGVVAILLIGLGLLHRDPELSVLAFTLSGACLGFLVHNHHRARLFMGDTG
SLGLGGALAGLALLGDQLWALALMGGVLVAEALSVMLQVGYFQYTKRKTGTGQRLLRMSPLHHHLELGGWSEVQVVGSFY
GVTALLVGLGWAWWHWTGM

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=331, Percent_Identity=39.5770392749245, Blast_Score=186, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_SYNJB (Q2JMC1)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_477386.1
- STRING:   Q2JMC1
- GeneID:   3900634
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_1146
- TIGR:   CYB_1146
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   TFWQFRN
- ProtClustDB:   PRK00108
- BioCyc:   SSP321332:CYB_1146-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 36118; Mature: 35987

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12b05670)-; HASH(0x138770c0)-; HASH(0x134ed324)-; HASH(0x122bdba8)-; HASH(0x13877264)-; HASH(0x13874bcc)-; HASH(0x134ada54)-; HASH(0x13815754)-; HASH(0x1353ed58)-; HASH(0x13874c5c)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSLGLGLALSALVIGIRPQVVVPFGLSALGSALLGSLLIPGLRRWKAGQVIRQEGPQS
CEEEHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
HQKKAGTPTMGGISFLPVGLLVAGIWSGWDPHWLAVALLTLAYSFVGWLDDWLVIRQQSN
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
KGLSPQHKLLLQVGVALGFCVYLAWQGIPTSLTLPGIGTLSLGWLFWPLALFVLVGTNNA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCE
VNLTDGMDGLAAGVVAILLIGLGLLHRDPELSVLAFTLSGACLGFLVHNHHRARLFMGDT
EECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHCCCEEEEEECCC
GSLGLGGALAGLALLGDQLWALALMGGVLVAEALSVMLQVGYFQYTKRKTGTGQRLLRMS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
PLHHHLELGGWSEVQVVGSFYGVTALLVGLGWAWWHWTGM
CHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHEECCH
>Mature Secondary Structure 
ALSLGLGLALSALVIGIRPQVVVPFGLSALGSALLGSLLIPGLRRWKAGQVIRQEGPQS
EEEHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
HQKKAGTPTMGGISFLPVGLLVAGIWSGWDPHWLAVALLTLAYSFVGWLDDWLVIRQQSN
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
KGLSPQHKLLLQVGVALGFCVYLAWQGIPTSLTLPGIGTLSLGWLFWPLALFVLVGTNNA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCE
VNLTDGMDGLAAGVVAILLIGLGLLHRDPELSVLAFTLSGACLGFLVHNHHRARLFMGDT
EECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHCCCEEEEEECCC
GSLGLGGALAGLALLGDQLWALALMGGVLVAEALSVMLQVGYFQYTKRKTGTGQRLLRMS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
PLHHHLELGGWSEVQVVGSFYGVTALLVGLGWAWWHWTGM
CHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHEECCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA