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The map label for this gene is recQ [H]

Identifier: 86608155

GI number: 86608155

Start: 683073

End: 684488

Strand: Reverse

Name: recQ [H]

Synonym: CYB_0669

Alternate gene names: 86608155

Gene position: 684488-683073 (Counterclockwise)

Preceding gene: 86608165

Following gene: 86608154

Centisome position: 22.47

GC content: 63.14

Gene sequence:

>1416_bases
TTGCAGGATTGGCAGCAAATCCAACAGGCCCTCAAGCAACACTGGGGTTACGAGACGCTGCGCCCACCCCAGGATCAGGT
GATCCGCGCTCTGCTGGACAAGCGCGACGCGCTGGTGGTGTTGCCGACGGGGTTTGGCAAATCCCTGTGCTTTCAGCTAG
CAGCTCTGCTGCAAAGGGGGGTGATGCTGGTGGTTTCACCCCTAATCGCCCTCATGGAAGACCAAGTTCAGGATCTTTGG
AAACGCAAGCTGCCGGCAGCCTGTCTCCACAGCGAACTGGATCCGGCCCTGCGCAAGCGGGTGTTGAAGGCCCTTGAGGA
AAACCGACTGCGCCTGCTCTATTTGGGGCCGGAGACCCTATTCAGCCCCCCCGTTTGGCAACGGCTGCAACAGCCTCAGG
TGCACATCAACGGCCTGATCGTGGATGAGGCCCATACGTTGGTGCATTGGGGGGGATCCTTCCGGCCCGACTACCGCCGT
CTGGGATTGCTGCGCCCGGCTCTGGCCCCGGTGAAGTCCTCCTTTCCCATTGCCGCTTTTACCGCCACGGCTGACCCCCA
AACCTGCAGCCGCCTCAGCCAAATCCTAGAGCTGCGGGATCCGGAGCACATTCGCGCCGATCCCCTGCGGGCCAACCTCT
CCCTCAATGTGGCGATAGCCTGGAGCCCGGCGGATCGCCGTCGTCGTCTGCTGCGATTCCTGGGCGAGAATCCCGGGTCG
GGTCTGGTCTATGTGCGCACCCGACGGGATGGGGAAGAGCTGGCCGAGTGGCTGGGCCGACAGAACTTGAAAACCGCCAC
CTACCATGGGGGACTGGAAGCGGGATCCCGCCGTCGGCTGGAACGGGCCTGGCTGCAGGGGGAACTGCGCTTTCTGGTCT
GCACCAACGCCTTTGGCATGGGCATCAACAAGCCGGACGTGCGTTGGGTACTGCACTTTCATCCCCCGCCCAGCTTGATG
GATTATTTGCAAGAGGTGGGGCGAGGTGGTCGGGATGGTGGCCCTTGTCGGGCCCTGATGCTGGTCTCGGAGCCGACGGG
CATGCTGGATCCCAGCGATCGCCGGCGCCAAGCCTATTTCTATTCCCAGCAGGAGCGCCTTCAGGCCCGAGCACGCCACC
TGCTCCAAACCCTACCCCAGCAGGGATCCTACGCCGACCTGCCGCCTGGAGAGGTACGGGTGGCCCTGGGTCTATTGCAG
GAGATGGGCTGCCTGCACTGGCCGGATCCCTTTCACTTTCAGGTGTTACACCGCCGTTGGCAGCCTTTAAGACGAGAGGA
TCCCTGGCAAGGGATGGAAGCCCTCATCCACGCCCGCGGCTGTCGGTGGCAGGCGATCTTGCCCTATTTTGGCTACCCTG
GGGAGCAGCCCGGCCTGCCCTGTGGCACCTGTGACCGTTGTCGGCTTTCTCGTTAG

Upstream 100 bases:

>100_bases
GAGCTAGCAGGTTCAGCGGGATTTGAAATAGCCTATAAGACAGCTTCTCCCGAAATCGCTGTAGATTGCTGAAGGAAATT
GTTGAAAAGGGGGTTGCCGT

Downstream 100 bases:

>100_bases
CCCTCAACAGCCCGCTGCGAGCCGCAACCGGCAGGAGTGGCTATCATGATCTGCGTTTCTGCAAAGGGAGCAGTTCCCCT
TGCTGACGAACTTTCGGCTG

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MQDWQQIQQALKQHWGYETLRPPQDQVIRALLDKRDALVVLPTGFGKSLCFQLAALLQRGVMLVVSPLIALMEDQVQDLW
KRKLPAACLHSELDPALRKRVLKALEENRLRLLYLGPETLFSPPVWQRLQQPQVHINGLIVDEAHTLVHWGGSFRPDYRR
LGLLRPALAPVKSSFPIAAFTATADPQTCSRLSQILELRDPEHIRADPLRANLSLNVAIAWSPADRRRRLLRFLGENPGS
GLVYVRTRRDGEELAEWLGRQNLKTATYHGGLEAGSRRRLERAWLQGELRFLVCTNAFGMGINKPDVRWVLHFHPPPSLM
DYLQEVGRGGRDGGPCRALMLVSEPTGMLDPSDRRRQAYFYSQQERLQARARHLLQTLPQQGSYADLPPGEVRVALGLLQ
EMGCLHWPDPFHFQVLHRRWQPLRREDPWQGMEALIHARGCRWQAILPYFGYPGEQPGLPCGTCDRCRLSR

Sequences:

>Translated_471_residues
MQDWQQIQQALKQHWGYETLRPPQDQVIRALLDKRDALVVLPTGFGKSLCFQLAALLQRGVMLVVSPLIALMEDQVQDLW
KRKLPAACLHSELDPALRKRVLKALEENRLRLLYLGPETLFSPPVWQRLQQPQVHINGLIVDEAHTLVHWGGSFRPDYRR
LGLLRPALAPVKSSFPIAAFTATADPQTCSRLSQILELRDPEHIRADPLRANLSLNVAIAWSPADRRRRLLRFLGENPGS
GLVYVRTRRDGEELAEWLGRQNLKTATYHGGLEAGSRRRLERAWLQGELRFLVCTNAFGMGINKPDVRWVLHFHPPPSLM
DYLQEVGRGGRDGGPCRALMLVSEPTGMLDPSDRRRQAYFYSQQERLQARARHLLQTLPQQGSYADLPPGEVRVALGLLQ
EMGCLHWPDPFHFQVLHRRWQPLRREDPWQGMEALIHARGCRWQAILPYFGYPGEQPGLPCGTCDRCRLSR
>Mature_471_residues
MQDWQQIQQALKQHWGYETLRPPQDQVIRALLDKRDALVVLPTGFGKSLCFQLAALLQRGVMLVVSPLIALMEDQVQDLW
KRKLPAACLHSELDPALRKRVLKALEENRLRLLYLGPETLFSPPVWQRLQQPQVHINGLIVDEAHTLVHWGGSFRPDYRR
LGLLRPALAPVKSSFPIAAFTATADPQTCSRLSQILELRDPEHIRADPLRANLSLNVAIAWSPADRRRRLLRFLGENPGS
GLVYVRTRRDGEELAEWLGRQNLKTATYHGGLEAGSRRRLERAWLQGELRFLVCTNAFGMGINKPDVRWVLHFHPPPSLM
DYLQEVGRGGRDGGPCRALMLVSEPTGMLDPSDRRRQAYFYSQQERLQARARHLLQTLPQQGSYADLPPGEVRVALGLLQ
EMGCLHWPDPFHFQVLHRRWQPLRREDPWQGMEALIHARGCRWQAILPYFGYPGEQPGLPCGTCDRCRLSR

Specific function: DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI51242943, Length=352, Percent_Identity=38.0681818181818, Blast_Score=215, Evalue=7e-56,
Organism=Homo sapiens, GI51242947, Length=352, Percent_Identity=38.0681818181818, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI148612816, Length=352, Percent_Identity=38.0681818181818, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI169218196, Length=337, Percent_Identity=34.7181008902077, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI110735439, Length=336, Percent_Identity=35.1190476190476, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI284005309, Length=420, Percent_Identity=35.9523809523809, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI4557365, Length=348, Percent_Identity=31.8965517241379, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI14591902, Length=338, Percent_Identity=33.1360946745562, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI14591904, Length=338, Percent_Identity=33.1360946745562, Blast_Score=174, Evalue=2e-43,
Organism=Escherichia coli, GI48994977, Length=463, Percent_Identity=34.7732181425486, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI87082221, Length=356, Percent_Identity=25.8426966292135, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787016, Length=349, Percent_Identity=25.7879656160458, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71987993, Length=343, Percent_Identity=36.1516034985423, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI71987997, Length=343, Percent_Identity=36.1516034985423, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17552866, Length=331, Percent_Identity=35.0453172205438, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI25145561, Length=352, Percent_Identity=34.9431818181818, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI32564293, Length=344, Percent_Identity=33.4302325581395, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI71995718, Length=385, Percent_Identity=25.4545454545455, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17510307, Length=356, Percent_Identity=26.4044943820225, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17510309, Length=356, Percent_Identity=26.4044943820225, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71995514, Length=356, Percent_Identity=26.4044943820225, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323844, Length=327, Percent_Identity=33.9449541284404, Blast_Score=194, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24646066, Length=335, Percent_Identity=35.2238805970149, Blast_Score=201, Evalue=8e-52,
Organism=Drosophila melanogaster, GI24664226, Length=351, Percent_Identity=37.037037037037, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI62472181, Length=351, Percent_Identity=37.037037037037, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24664230, Length=351, Percent_Identity=37.037037037037, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI21358123, Length=401, Percent_Identity=32.4189526184539, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24584399, Length=130, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 53893; Mature: 53893

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDWQQIQQALKQHWGYETLRPPQDQVIRALLDKRDALVVLPTGFGKSLCFQLAALLQRG
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHC
VMLVVSPLIALMEDQVQDLWKRKLPAACLHSELDPALRKRVLKALEENRLRLLYLGPETL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCEEEEEECCHHH
FSPPVWQRLQQPQVHINGLIVDEAHTLVHWGGSFRPDYRRLGLLRPALAPVKSSFPIAAF
CCCHHHHHHCCCCEEEEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEE
TATADPQTCSRLSQILELRDPEHIRADPLRANLSLNVAIAWSPADRRRRLLRFLGENPGS
EECCCHHHHHHHHHHHHCCCCCCCCCCCCEECEEEEEEEEECCHHHHHHHHHHHCCCCCC
GLVYVRTRRDGEELAEWLGRQNLKTATYHGGLEAGSRRRLERAWLQGELRFLVCTNAFGM
CEEEEEECCCHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCC
GINKPDVRWVLHFHPPPSLMDYLQEVGRGGRDGGPCRALMLVSEPTGMLDPSDRRRQAYF
CCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHH
YSQQERLQARARHLLQTLPQQGSYADLPPGEVRVALGLLQEMGCLHWPDPFHFQVLHRRW
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
QPLRREDPWQGMEALIHARGCRWQAILPYFGYPGEQPGLPCGTCDRCRLSR
CCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQDWQQIQQALKQHWGYETLRPPQDQVIRALLDKRDALVVLPTGFGKSLCFQLAALLQRG
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHC
VMLVVSPLIALMEDQVQDLWKRKLPAACLHSELDPALRKRVLKALEENRLRLLYLGPETL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCEEEEEECCHHH
FSPPVWQRLQQPQVHINGLIVDEAHTLVHWGGSFRPDYRRLGLLRPALAPVKSSFPIAAF
CCCHHHHHHCCCCEEEEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEE
TATADPQTCSRLSQILELRDPEHIRADPLRANLSLNVAIAWSPADRRRRLLRFLGENPGS
EECCCHHHHHHHHHHHHCCCCCCCCCCCCEECEEEEEEEEECCHHHHHHHHHHHCCCCCC
GLVYVRTRRDGEELAEWLGRQNLKTATYHGGLEAGSRRRLERAWLQGELRFLVCTNAFGM
CEEEEEECCCHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCC
GINKPDVRWVLHFHPPPSLMDYLQEVGRGGRDGGPCRALMLVSEPTGMLDPSDRRRQAYF
CCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHH
YSQQERLQARARHLLQTLPQQGSYADLPPGEVRVALGLLQEMGCLHWPDPFHFQVLHRRW
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
QPLRREDPWQGMEALIHARGCRWQAILPYFGYPGEQPGLPCGTCDRCRLSR
CCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]