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The map label for this gene is lon [H]

Identifier: 86607988

GI number: 86607988

Start: 506813

End: 507466

Strand: Direct

Name: lon [H]

Synonym: CYB_0494

Alternate gene names: 86607988

Gene position: 506813-507466 (Clockwise)

Preceding gene: 86607987

Following gene: 86607990

Centisome position: 16.63

GC content: 59.94

Gene sequence:

>654_bases
ATGCCTTCTTCTTCCGTGGATGTTCGCGAGCTACCGCTGTTTCCCTTGCCGGAGGTGGTGCTGTTTCCGGGCCGACCTCT
GCCGCTGCACATTTTCGAGTACCGCTACCGCATGATGATCAACACCATTCTGGAGACGGATCGCCGCTTTGGGGTGCTGA
TGTTCAATCCCCAGACGGGATCCCCAGTGCGGGTGGGCTGTTGTGCTGAGGTGTTGCAGGTGCAGCGATTGCCGGATGAC
CGCATGGACATTTTGACCTTGGGGCAGCAGCGCTTCCGCGTCTTGGATTACGTGCGGGAAAAACCCTTCCGGGTGGGGCT
GGTGGAATGGATTGAGGATGAGCCGACCACCCCTTCCGATGACCTGCAGAGCTGGGTGCGCCAGGTTACCACTCTCCTTC
AAGATGTGGTGCGTCTCTCGGGCAAGCTAATGGAGCGGGATGCACAGTTGCCGGAGCAGCTCCCCACCACCCCCATAGAA
CTGTCCTACTGGGTGGCTAGCCACTTCCATGGGGCCCCCCAAGAGCAGCAAGCTCTGCTGGAAATGGTCAGTACCGAAAG
GCGGCTGCGCCGGGAAGCCGAAATTCTCGAGTCCACCCGCAAGCACTTGGCCGCCCGCACGGCCCTCAAGGATCTGTTCA
CGGAAATTTCCTGA

Upstream 100 bases:

>100_bases
CTTGAGGGATCCCCTCCCTGTCAATCCCCTACCTTTAGCAGAGATAAAGATTGGCCAATAAAGATGGGCTAGACTCAGTA
CAGCGAGAAGCACAAGCCCT

Downstream 100 bases:

>100_bases
GGTTCCTGTCAGTTGGTCAGGTCTGCTCCCATCTGTTCTGGTGGCTCTTGTGGACCTTTCCAGAGAGTGCCCTTTGCCTT
GCTCGACCAGGCAGAGCAGA

Product: ATP-dependent protease La

Products: NA

Alternate protein names: ATP-dependent protease La [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MPSSSVDVRELPLFPLPEVVLFPGRPLPLHIFEYRYRMMINTILETDRRFGVLMFNPQTGSPVRVGCCAEVLQVQRLPDD
RMDILTLGQQRFRVLDYVREKPFRVGLVEWIEDEPTTPSDDLQSWVRQVTTLLQDVVRLSGKLMERDAQLPEQLPTTPIE
LSYWVASHFHGAPQEQQALLEMVSTERRLRREAEILESTRKHLAARTALKDLFTEIS

Sequences:

>Translated_217_residues
MPSSSVDVRELPLFPLPEVVLFPGRPLPLHIFEYRYRMMINTILETDRRFGVLMFNPQTGSPVRVGCCAEVLQVQRLPDD
RMDILTLGQQRFRVLDYVREKPFRVGLVEWIEDEPTTPSDDLQSWVRQVTTLLQDVVRLSGKLMERDAQLPEQLPTTPIE
LSYWVASHFHGAPQEQQALLEMVSTERRLRREAEILESTRKHLAARTALKDLFTEIS
>Mature_216_residues
PSSSVDVRELPLFPLPEVVLFPGRPLPLHIFEYRYRMMINTILETDRRFGVLMFNPQTGSPVRVGCCAEVLQVQRLPDDR
MDILTLGQQRFRVLDYVREKPFRVGLVEWIEDEPTTPSDDLQSWVRQVTTLLQDVVRLSGKLMERDAQLPEQLPTTPIEL
SYWVASHFHGAPQEQQALLEMVSTERRLRREAEILESTRKHLAARTALKDLFTEIS

Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced

COG id: COG2802

COG function: function code R; Uncharacterized protein, similar to the N-terminal domain of Lon protease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Lon domain [H]

Homologues:

Organism=Homo sapiens, GI37622896, Length=197, Percent_Identity=29.9492385786802, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI73747840, Length=197, Percent_Identity=29.9492385786802, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI87080813, Length=204, Percent_Identity=26.4705882352941, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI148528975, Length=197, Percent_Identity=29.4416243654822, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008269
- InterPro:   IPR004815
- InterPro:   IPR003111
- InterPro:   IPR008268
- InterPro:   IPR001984
- InterPro:   IPR015947
- InterPro:   IPR020568 [H]

Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]

EC number: =3.4.21.53 [H]

Molecular weight: Translated: 25182; Mature: 25051

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSSVDVRELPLFPLPEVVLFPGRPLPLHIFEYRYRMMINTILETDRRFGVLMFNPQTG
CCCCCCCHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
SPVRVGCCAEVLQVQRLPDDRMDILTLGQQRFRVLDYVREKPFRVGLVEWIEDEPTTPSD
CCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHH
DLQSWVRQVTTLLQDVVRLSGKLMERDAQLPEQLPTTPIELSYWVASHFHGAPQEQQALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHCCCCCHHHHHHH
EMVSTERRLRREAEILESTRKHLAARTALKDLFTEIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PSSSVDVRELPLFPLPEVVLFPGRPLPLHIFEYRYRMMINTILETDRRFGVLMFNPQTG
CCCCCCHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
SPVRVGCCAEVLQVQRLPDDRMDILTLGQQRFRVLDYVREKPFRVGLVEWIEDEPTTPSD
CCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHH
DLQSWVRQVTTLLQDVVRLSGKLMERDAQLPEQLPTTPIELSYWVASHFHGAPQEQQALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHCCCCCHHHHHHH
EMVSTERRLRREAEILESTRKHLAARTALKDLFTEIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA