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The map label for this gene is ppnK [H]

Identifier: 86607959

GI number: 86607959

Start: 469831

End: 470799

Strand: Reverse

Name: ppnK [H]

Synonym: CYB_0465

Alternate gene names: 86607959

Gene position: 470799-469831 (Counterclockwise)

Preceding gene: 86607961

Following gene: 86607958

Centisome position: 15.45

GC content: 60.37

Gene sequence:

>969_bases
ATGGACTTGGGCTTGGTGGTGATTGCCTACAAAGAGGGGGATCGGGAGAGCAAAGCCGCCTGCCAGAGGTGTGCGGAGCA
GTTGCGCCGGCGCGGTGTTACGGTGTTAACGGCTCCCACCGGCTTGCACCACAACCCCTACCCAGTCTTTTTGGAGGCCA
CCTCGGATCCCATCGATCTGGCGGTGGTGCTGGGGGGAGATGGCTCGGTGTTGGCGGCGGCACGATACCTGGCTCCCCAT
GGGATCCCGATTTTGCCGATCAAAGCGGGGGGTAGGCTGGGGTTTTTGGCCCAGTCGGAGCGGGTGCTGCAACAGGATCC
CTGGGATCGCATTCAGGCAGGGGATTTTTTCTTGCAAGCCCGCATGATGTTGCAAGCCCAGATTTGGGAACAGCCGCAGT
TGGGGCAAGGGGATCCCTTGGCCGCCCGTGGAGAGGGAAAGTCGCAAGGCCGTCCGGTTAGCGAAGTCTACTATGCCCTC
AATGAGATCTGCCTGAAGCCGATCAACCGAGAACGGCTGCCCGCCGCGATCATGGAGATCGAGGTCAACGGAGAGATTTT
GGATCAGTACCACGGGGATGGCGTGCTGGTGGCCACACCGACGGGATCCACCTCTTACACTCTGGCAGCCAATGGCCCCA
TCCTCGAGCCCACCCTCGACGCCATCATCATCACCCCTATTTGTCCCCTGAGTTTGTCTAGCCGTCCTATTGTCATCAGC
GGCACAGCCAGGGTGGACATTTGGCCTCTTGCCGATCCCGAAGGGTTGACCCGCCTGTGGACAGATGGCGTGTTGGCCCA
GTCGGTGAATCCCGGCCAGTGGGTTCACATTCAGCAAGCGCCTACACCGGCCAAGCTGATGATCCTGGAAAAAGAGCTCT
CCTACTTTCGCACTCTGCGGGAAAAACTGCAGTGGGCGGGCAGCCGCATTTACATCCCCACCACCAACCACCGCCCCGAA
GGGGGATAA

Upstream 100 bases:

>100_bases
ATTTTCTGGTTAACTTTGGGGGGGAGAGTCTGGATTATCCTGAGCAATCCCCAGCCTGAAGAAGGGGACAATCGACAGGG
ATCCCTTGATGAGGTTGACC

Downstream 100 bases:

>100_bases
GGAGAGCTAGAGTGGCGAAGTTCACCACCCATCCGCACATCTCCCATGAGCCTGAGACTTTACCTCCTCAGACACGGCGA
AACTCCCTACAGCCGTTCCG

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 2 [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MDLGLVVIAYKEGDRESKAACQRCAEQLRRRGVTVLTAPTGLHHNPYPVFLEATSDPIDLAVVLGGDGSVLAAARYLAPH
GIPILPIKAGGRLGFLAQSERVLQQDPWDRIQAGDFFLQARMMLQAQIWEQPQLGQGDPLAARGEGKSQGRPVSEVYYAL
NEICLKPINRERLPAAIMEIEVNGEILDQYHGDGVLVATPTGSTSYTLAANGPILEPTLDAIIITPICPLSLSSRPIVIS
GTARVDIWPLADPEGLTRLWTDGVLAQSVNPGQWVHIQQAPTPAKLMILEKELSYFRTLREKLQWAGSRIYIPTTNHRPE
GG

Sequences:

>Translated_322_residues
MDLGLVVIAYKEGDRESKAACQRCAEQLRRRGVTVLTAPTGLHHNPYPVFLEATSDPIDLAVVLGGDGSVLAAARYLAPH
GIPILPIKAGGRLGFLAQSERVLQQDPWDRIQAGDFFLQARMMLQAQIWEQPQLGQGDPLAARGEGKSQGRPVSEVYYAL
NEICLKPINRERLPAAIMEIEVNGEILDQYHGDGVLVATPTGSTSYTLAANGPILEPTLDAIIITPICPLSLSSRPIVIS
GTARVDIWPLADPEGLTRLWTDGVLAQSVNPGQWVHIQQAPTPAKLMILEKELSYFRTLREKLQWAGSRIYIPTTNHRPE
GG
>Mature_322_residues
MDLGLVVIAYKEGDRESKAACQRCAEQLRRRGVTVLTAPTGLHHNPYPVFLEATSDPIDLAVVLGGDGSVLAAARYLAPH
GIPILPIKAGGRLGFLAQSERVLQQDPWDRIQAGDFFLQARMMLQAQIWEQPQLGQGDPLAARGEGKSQGRPVSEVYYAL
NEICLKPINRERLPAAIMEIEVNGEILDQYHGDGVLVATPTGSTSYTLAANGPILEPTLDAIIITPICPLSLSSRPIVIS
GTARVDIWPLADPEGLTRLWTDGVLAQSVNPGQWVHIQQAPTPAKLMILEKELSYFRTLREKLQWAGSRIYIPTTNHRPE
GG

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=265, Percent_Identity=29.4339622641509, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1788968, Length=250, Percent_Identity=33.6, Blast_Score=119, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320794, Length=262, Percent_Identity=30.5343511450382, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6325068, Length=224, Percent_Identity=31.25, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322509, Length=192, Percent_Identity=31.7708333333333, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573832, Length=258, Percent_Identity=28.6821705426357, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573830, Length=258, Percent_Identity=28.6821705426357, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573828, Length=258, Percent_Identity=28.6821705426357, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161077047, Length=258, Percent_Identity=28.6821705426357, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24653422, Length=277, Percent_Identity=28.8808664259928, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28573826, Length=258, Percent_Identity=28.6821705426357, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281363321, Length=277, Percent_Identity=28.8808664259928, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI20129957, Length=277, Percent_Identity=28.8808664259928, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281363323, Length=277, Percent_Identity=28.8808664259928, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24653424, Length=277, Percent_Identity=28.8808664259928, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 35144; Mature: 35144

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGLVVIAYKEGDRESKAACQRCAEQLRRRGVTVLTAPTGLHHNPYPVFLEATSDPIDL
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCCEEE
AVVLGGDGSVLAAARYLAPHGIPILPIKAGGRLGFLAQSERVLQQDPWDRIQAGDFFLQA
EEEECCCCCHHHHHHHHCCCCCEEEEEECCCCEEEHHHCCHHHHCCCCCHHHCCHHHHHH
RMMLQAQIWEQPQLGQGDPLAARGEGKSQGRPVSEVYYALNEICLKPINRERLPAAIMEI
HHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEE
EVNGEILDQYHGDGVLVATPTGSTSYTLAANGPILEPTLDAIIITPICPLSLSSRPIVIS
EECCCEEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCEEEE
GTARVDIWPLADPEGLTRLWTDGVLAQSVNPGQWVHIQQAPTPAKLMILEKELSYFRTLR
CCCEEEEEECCCCCCHHHHHCCCHHCCCCCCCCEEEEECCCCCEEEEEEHHHHHHHHHHH
EKLQWAGSRIYIPTTNHRPEGG
HHHHHCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MDLGLVVIAYKEGDRESKAACQRCAEQLRRRGVTVLTAPTGLHHNPYPVFLEATSDPIDL
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCCEEE
AVVLGGDGSVLAAARYLAPHGIPILPIKAGGRLGFLAQSERVLQQDPWDRIQAGDFFLQA
EEEECCCCCHHHHHHHHCCCCCEEEEEECCCCEEEHHHCCHHHHCCCCCHHHCCHHHHHH
RMMLQAQIWEQPQLGQGDPLAARGEGKSQGRPVSEVYYALNEICLKPINRERLPAAIMEI
HHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEE
EVNGEILDQYHGDGVLVATPTGSTSYTLAANGPILEPTLDAIIITPICPLSLSSRPIVIS
EECCCEEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCEEEE
GTARVDIWPLADPEGLTRLWTDGVLAQSVNPGQWVHIQQAPTPAKLMILEKELSYFRTLR
CCCEEEEEECCCCCCHHHHHCCCHHCCCCCCCCEEEEECCCCCEEEEEEHHHHHHHHHHH
EKLQWAGSRIYIPTTNHRPEGG
HHHHHCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]