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The map label for this gene is cobC [C]

Identifier: 86607958

GI number: 86607958

Start: 469147

End: 469785

Strand: Reverse

Name: cobC [C]

Synonym: CYB_0464

Alternate gene names: 86607958

Gene position: 469785-469147 (Counterclockwise)

Preceding gene: 86607959

Following gene: 86607957

Centisome position: 15.42

GC content: 59.78

Gene sequence:

>639_bases
ATGAGCCTGAGACTTTACCTCCTCAGACACGGCGAAACTCCCTACAGCCGTTCCGGCAGCTTTTGCGGCGCTCTCGATCC
CGACCTCACCCCCGAAGGCAAACAAATGGCAGAAGCCTTTGCCGCAGCCTATGCTGGGATCCCTTGGCAAGCTCTCTACG
TCAGCCCAATGCGGCGCGCCTTGGCTACCCTAAGCCCCCTGGCCGAGAAAGTTGGCTTGGAGATGCAGATTCGAGAGGGC
CTAAGAGAAATTCACTACGGCGAGTGGGAGGGCAAAACCCACGCTGAGGCGCAAGAAGCCTACCCAGAAGCCTATTGGCG
CTGGATGACCGAGCCGGCCTGGAACGCCCCTCCGGGGGGCGAAACCGCCGTGCAAATTGCCAATCGGGCCATGCCGGTTG
TGGCCGAGATCCAGGAAAAATGGACAGGCGGCCACGTCTTGATCGTCTCCCACAAGGCCACCATTCGGGTTATTCTCTGC
AGCCTGCTGGGCATCGACCTGGGTCGCTACCGGGATCGCATTGAGGTTTTGGCCGCCTCGGTCAGCGTGGTCAAGTTCGA
CCGCTATGGCCCCCTTCTGGAAATCTTAGGGGAACGCAGTTATCTGCCTTCCGATCTGCGAGAAAGGGCAGGTACCTAA

Upstream 100 bases:

>100_bases
GGCGGGCAGCCGCATTTACATCCCCACCACCAACCACCGCCCCGAAGGGGGATAAGGAGAGCTAGAGTGGCGAAGTTCAC
CACCCATCCGCACATCTCCC

Downstream 100 bases:

>100_bases
TTGTTAGAGGGAGCAAGGTTTAGGATTCTTGAGGTCTTTTGGGTCTCTTTTTGAGGGAGCAATCATGGGCAAAAAACTGG
GATTAGCACTGGGCAGCGGC

Product: phosphoglycerate mutase family protein

Products: NA

Alternate protein names: Phosphoglyceromutase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSLRLYLLRHGETPYSRSGSFCGALDPDLTPEGKQMAEAFAAAYAGIPWQALYVSPMRRALATLSPLAEKVGLEMQIREG
LREIHYGEWEGKTHAEAQEAYPEAYWRWMTEPAWNAPPGGETAVQIANRAMPVVAEIQEKWTGGHVLIVSHKATIRVILC
SLLGIDLGRYRDRIEVLAASVSVVKFDRYGPLLEILGERSYLPSDLRERAGT

Sequences:

>Translated_212_residues
MSLRLYLLRHGETPYSRSGSFCGALDPDLTPEGKQMAEAFAAAYAGIPWQALYVSPMRRALATLSPLAEKVGLEMQIREG
LREIHYGEWEGKTHAEAQEAYPEAYWRWMTEPAWNAPPGGETAVQIANRAMPVVAEIQEKWTGGHVLIVSHKATIRVILC
SLLGIDLGRYRDRIEVLAASVSVVKFDRYGPLLEILGERSYLPSDLRERAGT
>Mature_211_residues
SLRLYLLRHGETPYSRSGSFCGALDPDLTPEGKQMAEAFAAAYAGIPWQALYVSPMRRALATLSPLAEKVGLEMQIREGL
REIHYGEWEGKTHAEAQEAYPEAYWRWMTEPAWNAPPGGETAVQIANRAMPVVAEIQEKWTGGHVLIVSHKATIRVILCS
LLGIDLGRYRDRIEVLAASVSVVKFDRYGPLLEILGERSYLPSDLRERAGT

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Homo sapiens, GI64762445, Length=162, Percent_Identity=31.4814814814815, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI64762406, Length=162, Percent_Identity=31.4814814814815, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4758902, Length=161, Percent_Identity=29.8136645962733, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786857, Length=163, Percent_Identity=26.3803680981595, Blast_Score=74, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24643264, Length=162, Percent_Identity=32.0987654320988, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643254, Length=162, Percent_Identity=32.0987654320988, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643260, Length=162, Percent_Identity=32.0987654320988, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643258, Length=162, Percent_Identity=32.0987654320988, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643256, Length=162, Percent_Identity=32.0987654320988, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643262, Length=162, Percent_Identity=32.0987654320988, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643252, Length=162, Percent_Identity=32.0987654320988, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17137706, Length=162, Percent_Identity=32.0987654320988, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 3.1.3.73 [C]

Molecular weight: Translated: 23640; Mature: 23509

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRLYLLRHGETPYSRSGSFCGALDPDLTPEGKQMAEAFAAAYAGIPWQALYVSPMRRA
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LATLSPLAEKVGLEMQIREGLREIHYGEWEGKTHAEAQEAYPEAYWRWMTEPAWNAPPGG
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
ETAVQIANRAMPVVAEIQEKWTGGHVLIVSHKATIRVILCSLLGIDLGRYRDRIEVLAAS
HHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVVKFDRYGPLLEILGERSYLPSDLRERAGT
HHHEEECCCCHHHHHHCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
SLRLYLLRHGETPYSRSGSFCGALDPDLTPEGKQMAEAFAAAYAGIPWQALYVSPMRRA
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LATLSPLAEKVGLEMQIREGLREIHYGEWEGKTHAEAQEAYPEAYWRWMTEPAWNAPPGG
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
ETAVQIANRAMPVVAEIQEKWTGGHVLIVSHKATIRVILCSLLGIDLGRYRDRIEVLAAS
HHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVVKFDRYGPLLEILGERSYLPSDLRERAGT
HHHEEECCCCHHHHHHCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]