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The map label for this gene is sds [H]

Identifier: 86607946

GI number: 86607946

Start: 457349

End: 458311

Strand: Direct

Name: sds [H]

Synonym: CYB_0451

Alternate gene names: 86607946

Gene position: 457349-458311 (Clockwise)

Preceding gene: 86607944

Following gene: 86607948

Centisome position: 15.01

GC content: 59.19

Gene sequence:

>963_bases
GTGCTCTCCCCCTTTGGCCCTGTAGAAGCGGATCTGGAGCGTTTACGCCAGAACCTAACGCGGTTGGTCAGTGCCAAGCA
CCCCATCCTGGCCATGGCTGCCGAACATCTGTTTTCGGCGGGGGGGAAAGGGATCCGGCCAGCCATCGTGCTCCTCATTG
CCCGTGCCACCACCCCAGATGGAGAGATTACCCCACGGCATTGGCGCTTGGCAGAGATTACTGAGATGATCCACACGGCC
AGCTTGGTTCACGACGATGTCATCGACGCTGCCGATGTGCGACGGGGCATCGATACGGTGAATACCCTCTTCGACAATCG
GATAGCCGTGCTGGCGGGGGATTACCTCTTCGGCCAAGCTGCTTGGTACTTGGCCAATCTGGACAACCTGGAGGTAGTGA
AGCTCCTTTCCAAAGTAATCATGGATTTGCCGGAGGGAGAGGTGCGCCAGAGCCTCACCCGCTTCGACCCGGATGTGTCG
ATGGAAGACTACCTGGCCAAGAGCTTCTACAAAACGGCCTCCCTCATGTCCGGCAGTTCCAAGGCTGCTGGCCTGCTGAG
CGGGGTTAGCGAGGAAGTGGCGGATCGCCTGTTCGATTTTGGGCGGGATCTGGGCATTGCTTTTCAGATTGTCGACGATC
TGCTGGATTTCACCGCTTCGGCAGAGACGCTTGGCAAGCCTGTGGGATCCGACCTCATCCAGGGCAACCTCACTGCACCC
GTTCTGTTTGCCCTAGAGGAATTTCCCCAGATGCGAGAGCTCATTCTCAGGGAGCTGTCCAACCCGCAAGACCTGAAGCA
GGCCCTGGAGTGGGTGTATCAAAGCGAAGGGATCCCACGCTCTCGTCAGTTGGCCCGCGACTACGCCCAGCGGGCTGCCG
AAGCGCTGTATAGCCTGCCGGACTCTGCGGCGCGTCGTGCTTTGTTTCAGATGGTGGACTATGTGCTGGAGCGGCTGCAC
TGA

Upstream 100 bases:

>100_bases
ATGATACCGCTTGGTTTTCCCCGAGAACGATGGGGTACTCTACAATAGAAAAAGATGTGAAATTTTGTAAAACCTCTCAT
ACTTTGGCTCCATGACCTCT

Downstream 100 bases:

>100_bases
GCAGTCCCGACAGGGTCAAGCTGGCTTTCTACCGGGCTGTGTTGCCCAACACTTGGGCCTCTGGAAGAAGCTCAGGATAT
TCTGGCGGGGCGAAAAAGTG

Product: solanesyl diphosphate synthase

Products: trans-polyisoprenyln-PP; pyrophosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MLSPFGPVEADLERLRQNLTRLVSAKHPILAMAAEHLFSAGGKGIRPAIVLLIARATTPDGEITPRHWRLAEITEMIHTA
SLVHDDVIDAADVRRGIDTVNTLFDNRIAVLAGDYLFGQAAWYLANLDNLEVVKLLSKVIMDLPEGEVRQSLTRFDPDVS
MEDYLAKSFYKTASLMSGSSKAAGLLSGVSEEVADRLFDFGRDLGIAFQIVDDLLDFTASAETLGKPVGSDLIQGNLTAP
VLFALEEFPQMRELILRELSNPQDLKQALEWVYQSEGIPRSRQLARDYAQRAAEALYSLPDSAARRALFQMVDYVLERLH

Sequences:

>Translated_320_residues
MLSPFGPVEADLERLRQNLTRLVSAKHPILAMAAEHLFSAGGKGIRPAIVLLIARATTPDGEITPRHWRLAEITEMIHTA
SLVHDDVIDAADVRRGIDTVNTLFDNRIAVLAGDYLFGQAAWYLANLDNLEVVKLLSKVIMDLPEGEVRQSLTRFDPDVS
MEDYLAKSFYKTASLMSGSSKAAGLLSGVSEEVADRLFDFGRDLGIAFQIVDDLLDFTASAETLGKPVGSDLIQGNLTAP
VLFALEEFPQMRELILRELSNPQDLKQALEWVYQSEGIPRSRQLARDYAQRAAEALYSLPDSAARRALFQMVDYVLERLH
>Mature_320_residues
MLSPFGPVEADLERLRQNLTRLVSAKHPILAMAAEHLFSAGGKGIRPAIVLLIARATTPDGEITPRHWRLAEITEMIHTA
SLVHDDVIDAADVRRGIDTVNTLFDNRIAVLAGDYLFGQAAWYLANLDNLEVVKLLSKVIMDLPEGEVRQSLTRFDPDVS
MEDYLAKSFYKTASLMSGSSKAAGLLSGVSEEVADRLFDFGRDLGIAFQIVDDLLDFTASAETLGKPVGSDLIQGNLTAP
VLFALEEFPQMRELILRELSNPQDLKQALEWVYQSEGIPRSRQLARDYAQRAAEALYSLPDSAARRALFQMVDYVLERLH

Specific function: Possible role in synthesis of the nonaprenyl side chain of plastoquinone or in synthesis of other prenyl chains such as undekaprenyl pyrophosphate [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=320, Percent_Identity=39.6875, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI169808399, Length=326, Percent_Identity=28.8343558282209, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4758430, Length=201, Percent_Identity=25.8706467661692, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI83700220, Length=201, Percent_Identity=25.8706467661692, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1789578, Length=287, Percent_Identity=37.9790940766551, Blast_Score=194, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17505681, Length=299, Percent_Identity=36.7892976588629, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6319475, Length=301, Percent_Identity=41.8604651162791, Blast_Score=212, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6325188, Length=251, Percent_Identity=25.8964143426295, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24651612, Length=325, Percent_Identity=34.7692307692308, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI21356309, Length=350, Percent_Identity=27.4285714285714, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR014120
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 35483; Mature: 35483

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSPFGPVEADLERLRQNLTRLVSAKHPILAMAAEHLFSAGGKGIRPAIVLLIARATTPD
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
GEITPRHWRLAEITEMIHTASLVHDDVIDAADVRRGIDTVNTLFDNRIAVLAGDYLFGQA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHH
AWYLANLDNLEVVKLLSKVIMDLPEGEVRQSLTRFDPDVSMEDYLAKSFYKTASLMSGSS
HHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
KAAGLLSGVSEEVADRLFDFGRDLGIAFQIVDDLLDFTASAETLGKPVGSDLIQGNLTAP
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
VLFALEEFPQMRELILRELSNPQDLKQALEWVYQSEGIPRSRQLARDYAQRAAEALYSLP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
DSAARRALFQMVDYVLERLH
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSPFGPVEADLERLRQNLTRLVSAKHPILAMAAEHLFSAGGKGIRPAIVLLIARATTPD
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
GEITPRHWRLAEITEMIHTASLVHDDVIDAADVRRGIDTVNTLFDNRIAVLAGDYLFGQA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHH
AWYLANLDNLEVVKLLSKVIMDLPEGEVRQSLTRFDPDVSMEDYLAKSFYKTASLMSGSS
HHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
KAAGLLSGVSEEVADRLFDFGRDLGIAFQIVDDLLDFTASAETLGKPVGSDLIQGNLTAP
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
VLFALEEFPQMRELILRELSNPQDLKQALEWVYQSEGIPRSRQLARDYAQRAAEALYSLP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
DSAARRALFQMVDYVLERLH
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trans-polyisoprenyln-PP; Delta3-isopentenyl-PP [C]

Specific reaction: trans-polyisoprenyln-PP + Delta3-isopentenyl-PP = trans-polyisoprenyln-PP + pyrophosphate [C]

General reaction: Transferring alkyl or aryl groups, other than methyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]