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The map label for this gene is cysQ [H]

Identifier: 86607939

GI number: 86607939

Start: 452438

End: 453265

Strand: Reverse

Name: cysQ [H]

Synonym: CYB_0444

Alternate gene names: 86607939

Gene position: 453265-452438 (Counterclockwise)

Preceding gene: 86607940

Following gene: 86607936

Centisome position: 14.88

GC content: 62.8

Gene sequence:

>828_bases
GTGCAGGCTCAAGATCTGGCCGCTCTCCTGCCTGAGGTGTGCCGCCTGGCAGAAGCAGCAGGGCAGGCCATCTTGCCCTT
CTATCGGCAAAAATCGCTGCCGATCCAACTCAAAGCAGATGCCTCCCCCCTAACTGAGGCGGATCTGGCTGCCCACCACC
TGATCCTGCAGGGCCTGCAAGAGTTGACCCCAGGGATCCCCCTCCTCTCGGAAGAATCCAGCGATATCCCCTACGCCCAG
CGGCAGGTGTGGCGGCACTTCTGGCTGGTGGATCCCTTGGATGGCACGCGCGAGTTTATCGAAGGCAGCGGCCAGTTCAC
CGTCAACATTGCCCTTGTCGAGGTGGGGATCCCCATCCTGGGGGTCGTCCATGCCCCAGCTCTGGGCCTCACCTACGCGG
CTGCGCAAAAGCTGGGGGCCTGCAAGAGGGAAAGGACTCCGTCCTGCGTTCACGAACAGCCCATCCGCACCTGCCCTTAC
GCCCAAGAACCCCTACAAGTGGTGGCCAGCCGTTCCCACAGCAACCCGGAGACGGAGCAGTTCCTCGAGCGGCTGCGGCA
GCGCTGTGGCTCTCTGGAAGTGAAGTCTGTGGGCAGTGCCCTAAAGCTTTGCCTTGTGGCCGAAGGATCTGCCCATCTCT
ACCCTCGCTTCGGCCCCACCATGGAGTGGGATACTGCCGCTGCCCAGTGCATTGTGGAGCAGGCGGGGGGAAGGGTTACC
GATCTGGTAGGGGATCCCTTGCGCTACAACAAGCCCGACCTGCACAACCCGCCCTTTGTAGCGGCTGCCGAAGGCATGGC
CCAACTGTGGCAGAACCTGATCCCCTGA

Upstream 100 bases:

>100_bases
GGCTTCTCTGTTGCACTACGGCCAGTTAACGATTGCCCAAATCAAAGCCGACTTGGCCGCCCACGGCATTCCGGTGCGTT
TCTAGCTTGGGGAGGGATCC

Downstream 100 bases:

>100_bases
GCGAAGCCCCGGCTACATGCCCATCTCTGTGGGGTTAAAGCCATCCGGGAACTTGGTGTACTCGTCGTAAAGGGCACCGC
GGAAATGGGTGTTGGTGATG

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MQAQDLAALLPEVCRLAEAAGQAILPFYRQKSLPIQLKADASPLTEADLAAHHLILQGLQELTPGIPLLSEESSDIPYAQ
RQVWRHFWLVDPLDGTREFIEGSGQFTVNIALVEVGIPILGVVHAPALGLTYAAAQKLGACKRERTPSCVHEQPIRTCPY
AQEPLQVVASRSHSNPETEQFLERLRQRCGSLEVKSVGSALKLCLVAEGSAHLYPRFGPTMEWDTAAAQCIVEQAGGRVT
DLVGDPLRYNKPDLHNPPFVAAAEGMAQLWQNLIP

Sequences:

>Translated_275_residues
MQAQDLAALLPEVCRLAEAAGQAILPFYRQKSLPIQLKADASPLTEADLAAHHLILQGLQELTPGIPLLSEESSDIPYAQ
RQVWRHFWLVDPLDGTREFIEGSGQFTVNIALVEVGIPILGVVHAPALGLTYAAAQKLGACKRERTPSCVHEQPIRTCPY
AQEPLQVVASRSHSNPETEQFLERLRQRCGSLEVKSVGSALKLCLVAEGSAHLYPRFGPTMEWDTAAAQCIVEQAGGRVT
DLVGDPLRYNKPDLHNPPFVAAAEGMAQLWQNLIP
>Mature_275_residues
MQAQDLAALLPEVCRLAEAAGQAILPFYRQKSLPIQLKADASPLTEADLAAHHLILQGLQELTPGIPLLSEESSDIPYAQ
RQVWRHFWLVDPLDGTREFIEGSGQFTVNIALVEVGIPILGVVHAPALGLTYAAAQKLGACKRERTPSCVHEQPIRTCPY
AQEPLQVVASRSHSNPETEQFLERLRQRCGSLEVKSVGSALKLCLVAEGSAHLYPRFGPTMEWDTAAAQCIVEQAGGRVT
DLVGDPLRYNKPDLHNPPFVAAAEGMAQLWQNLIP

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=255, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI221625487, Length=255, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1790659, Length=254, Percent_Identity=48.4251968503937, Blast_Score=200, Evalue=8e-53,
Organism=Escherichia coli, GI1788882, Length=248, Percent_Identity=25.4032258064516, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71995897, Length=283, Percent_Identity=28.6219081272085, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71995905, Length=283, Percent_Identity=28.6219081272085, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17537869, Length=287, Percent_Identity=29.616724738676, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641722, Length=271, Percent_Identity=26.1992619926199, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357329, Length=243, Percent_Identity=24.6913580246914, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 30035; Mature: 30035

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAQDLAALLPEVCRLAEAAGQAILPFYRQKSLPIQLKADASPLTEADLAAHHLILQGLQ
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
ELTPGIPLLSEESSDIPYAQRQVWRHFWLVDPLDGTREFIEGSGQFTVNIALVEVGIPIL
HHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEEEEECCCHHH
GVVHAPALGLTYAAAQKLGACKRERTPSCVHEQPIRTCPYAQEPLQVVASRSHSNPETEQ
HHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHH
FLERLRQRCGSLEVKSVGSALKLCLVAEGSAHLYPRFGPTMEWDTAAAQCIVEQAGGRVT
HHHHHHHHHCCCCHHHHHHHHHHHHEECCCCEECCCCCCCCCHHHHHHHHHHHHHCCEEE
DLVGDPLRYNKPDLHNPPFVAAAEGMAQLWQNLIP
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQAQDLAALLPEVCRLAEAAGQAILPFYRQKSLPIQLKADASPLTEADLAAHHLILQGLQ
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
ELTPGIPLLSEESSDIPYAQRQVWRHFWLVDPLDGTREFIEGSGQFTVNIALVEVGIPIL
HHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEEEEECCCHHH
GVVHAPALGLTYAAAQKLGACKRERTPSCVHEQPIRTCPYAQEPLQVVASRSHSNPETEQ
HHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHH
FLERLRQRCGSLEVKSVGSALKLCLVAEGSAHLYPRFGPTMEWDTAAAQCIVEQAGGRVT
HHHHHHHHHCCCCHHHHHHHHHHHHEECCCCEECCCCCCCCCHHHHHHHHHHHHHCCEEE
DLVGDPLRYNKPDLHNPPFVAAAEGMAQLWQNLIP
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]