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The map label for this gene is prk [H]

Identifier: 86607936

GI number: 86607936

Start: 449717

End: 450658

Strand: Reverse

Name: prk [H]

Synonym: CYB_0441

Alternate gene names: 86607936

Gene position: 450658-449717 (Counterclockwise)

Preceding gene: 86607939

Following gene: 86607929

Centisome position: 14.79

GC content: 54.88

Gene sequence:

>942_bases
GTGGCTCAGCGCCCGATTATTCTGGGTATTGTTGGTGATAGTGCTGCTGGAAAAACCACCCTCACCCGTGGCATTGCCCA
AGTCTTGGGGGAAGAAAACGTCACTGTCATCTGCACCGACGACTACCACCGCTACGACCGCAAACAACGCGCTGAACTGG
GGATTACAGCCCTCCATCCCGACTGCAACTACCTGGATATCGTTCAGCAGCACCTGACGCTCTTGCGCACCGGCCAGCCG
ATCCTAAAGCCCGTCTACAACCACAGCACCGGCACCTTTGACCCGCCAGAGTATGTCAAGCCCAACAAATACGTGATTGT
CGAAGGGCTGCTGGGCTACTTTACCCGTGGTATGCGGGATAGCTACGATGTCAAGGTTTATTTGGCCCCTCCCGAACATC
TACGCGCCCTCTGGAAGATTAAGCGGGACACCCGCAAGCGCGGATATACCGAAGAGCAAGTGCGAGAAGAGCTCAAAAAG
CGCGAACCCGACTCAGAGGCTTTTATTCGTCCACAGCGCCAATGGGCCGATGTAGTGGTCACCTTTTACCCGCCCCAAGA
GGGATCCGACCAAGACGAGGTATTGCTGAATGCACGCTTGGTGCTGCGCCCCACCATTCCTCACCCAGATTTTTGGCAAA
TCCTCAATGCCCGCGACAATCACCTTAGCTCTGCCATTCGTTTGGATTTGGATCGGGATATGGGCAAGCCCGTCGATGTT
TTGCAGATTGATGCCCATGCTACGGCCAGCCAAGTGATCGAATTGGAGCGGATGCTCTGCAACGAAATCCCTTACCTGGG
CAAGTTCTGTAGCTTAGAGGGAAACCCCAATATCGGCCAATTGATCGGCACCACCGGCGAGCTGCTCCAGAGCTATCCCC
TGGCTTTGACTCAGTTGCTGATCACCTACCACATGCTAAAAGCGGCCCATATCTACCAGTAG

Upstream 100 bases:

>100_bases
GTTCTCTGATCGGGGCCATCCGCAGGTCGAAACGAAGTTGAGTTTGGCCGGTGTTGTTGGGAGTTCTCCGCCCCAGGTTC
ACGATTCAGGAGAGGGATCC

Downstream 100 bases:

>100_bases
AATCCGTGGCGGTGAGGGATCCCCAGTTTCGCAAGACCTGCAGGGTAAGGCTCGGCCCAGCACGGTAACCCGCTCCCAGA
GCAGAGTCTTGTGAGCTTCT

Product: phosphoribulokinase

Products: NA

Alternate protein names: PRK; PRKase; Phosphopentokinase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MAQRPIILGIVGDSAAGKTTLTRGIAQVLGEENVTVICTDDYHRYDRKQRAELGITALHPDCNYLDIVQQHLTLLRTGQP
ILKPVYNHSTGTFDPPEYVKPNKYVIVEGLLGYFTRGMRDSYDVKVYLAPPEHLRALWKIKRDTRKRGYTEEQVREELKK
REPDSEAFIRPQRQWADVVVTFYPPQEGSDQDEVLLNARLVLRPTIPHPDFWQILNARDNHLSSAIRLDLDRDMGKPVDV
LQIDAHATASQVIELERMLCNEIPYLGKFCSLEGNPNIGQLIGTTGELLQSYPLALTQLLITYHMLKAAHIYQ

Sequences:

>Translated_313_residues
MAQRPIILGIVGDSAAGKTTLTRGIAQVLGEENVTVICTDDYHRYDRKQRAELGITALHPDCNYLDIVQQHLTLLRTGQP
ILKPVYNHSTGTFDPPEYVKPNKYVIVEGLLGYFTRGMRDSYDVKVYLAPPEHLRALWKIKRDTRKRGYTEEQVREELKK
REPDSEAFIRPQRQWADVVVTFYPPQEGSDQDEVLLNARLVLRPTIPHPDFWQILNARDNHLSSAIRLDLDRDMGKPVDV
LQIDAHATASQVIELERMLCNEIPYLGKFCSLEGNPNIGQLIGTTGELLQSYPLALTQLLITYHMLKAAHIYQ
>Mature_312_residues
AQRPIILGIVGDSAAGKTTLTRGIAQVLGEENVTVICTDDYHRYDRKQRAELGITALHPDCNYLDIVQQHLTLLRTGQPI
LKPVYNHSTGTFDPPEYVKPNKYVIVEGLLGYFTRGMRDSYDVKVYLAPPEHLRALWKIKRDTRKRGYTEEQVREELKKR
EPDSEAFIRPQRQWADVVVTFYPPQEGSDQDEVLLNARLVLRPTIPHPDFWQILNARDNHLSSAIRLDLDRDMGKPVDVL
QIDAHATASQVIELERMLCNEIPYLGKFCSLEGNPNIGQLIGTTGELLQSYPLALTQLLITYHMLKAAHIYQ

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoribulokinase family [H]

Homologues:

Organism=Homo sapiens, GI18699734, Length=189, Percent_Identity=25.3968253968254, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI13899253, Length=192, Percent_Identity=26.5625, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI301129207, Length=185, Percent_Identity=24.3243243243243, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI57863312, Length=185, Percent_Identity=24.3243243243243, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI87082034, Length=187, Percent_Identity=29.4117647058824, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17539892, Length=184, Percent_Identity=27.1739130434783, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17539894, Length=184, Percent_Identity=27.1739130434783, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221458995, Length=192, Percent_Identity=23.9583333333333, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24649624, Length=192, Percent_Identity=23.9583333333333, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45550449, Length=182, Percent_Identity=27.4725274725275, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28573516, Length=182, Percent_Identity=27.4725274725275, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28573514, Length=182, Percent_Identity=27.4725274725275, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28573512, Length=182, Percent_Identity=27.4725274725275, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006082
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.19 [H]

Molecular weight: Translated: 35711; Mature: 35580

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00567 PHOSPHORIBULOKINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRPIILGIVGDSAAGKTTLTRGIAQVLGEENVTVICTDDYHRYDRKQRAELGITALHP
CCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCEEEECC
DCNYLDIVQQHLTLLRTGQPILKPVYNHSTGTFDPPEYVKPNKYVIVEGLLGYFTRGMRD
CCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCC
SYDVKVYLAPPEHLRALWKIKRDTRKRGYTEEQVREELKKREPDSEAFIRPQRQWADVVV
CCCEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCEEE
TFYPPQEGSDQDEVLLNARLVLRPTIPHPDFWQILNARDNHLSSAIRLDLDRDMGKPVDV
EEECCCCCCCHHHEEEEEEEEEECCCCCCHHHHHHCCCHHHHHHHHEEECHHCCCCCCCE
LQIDAHATASQVIELERMLCNEIPYLGKFCSLEGNPNIGQLIGTTGELLQSYPLALTQLL
EEECCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHH
ITYHMLKAAHIYQ
HHHHHHHHHHHCC
>Mature Secondary Structure 
AQRPIILGIVGDSAAGKTTLTRGIAQVLGEENVTVICTDDYHRYDRKQRAELGITALHP
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCEEEECC
DCNYLDIVQQHLTLLRTGQPILKPVYNHSTGTFDPPEYVKPNKYVIVEGLLGYFTRGMRD
CCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCC
SYDVKVYLAPPEHLRALWKIKRDTRKRGYTEEQVREELKKREPDSEAFIRPQRQWADVVV
CCCEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCEEE
TFYPPQEGSDQDEVLLNARLVLRPTIPHPDFWQILNARDNHLSSAIRLDLDRDMGKPVDV
EEECCCCCCCHHHEEEEEEEEEECCCCCCHHHHHHCCCHHHHHHHHEEECHHCCCCCCCE
LQIDAHATASQVIELERMLCNEIPYLGKFCSLEGNPNIGQLIGTTGELLQSYPLALTQLL
EEECCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHH
ITYHMLKAAHIYQ
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1660882; 8905231 [H]