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The map label for this gene is purQ [H]

Identifier: 86607783

GI number: 86607783

Start: 298297

End: 298974

Strand: Reverse

Name: purQ [H]

Synonym: CYB_0284

Alternate gene names: 86607783

Gene position: 298974-298297 (Counterclockwise)

Preceding gene: 86607784

Following gene: 86607779

Centisome position: 9.81

GC content: 60.91

Gene sequence:

>678_bases
ATGGCTGGCGTGAGGTTTGGCGTTGTTGTTTTTCCGGGTTCCAACTGCGACCGAGATGTAGCCTGGGTAACCCGCGGCCT
CTTGGGCTGCCCAACGCGGCTGATCTGGCACCGAGAGACGGATTTGTCGGAGCTGGATGTGGTGGTGCTGCCGGGGGGCT
TCAGCTATGGGGATTATTTGCGTTGTGGGGCCATCGCTCGTTTTGCTCCGGTGATGGGATCCCTGAAGGAGCACGCGGCG
CGAGGGGGCTATGTGCTGGGCATTTGCAATGGCTTTCAGATCTTGACAGAGGCGGGCCTGCTGCCGGGGGCGCTGGTGCG
CAATGCCAACCTGCACTTTATCTGCGACCGAGTGGGGATCCGTGTAGAACGGCAGGATCTTCCCTGGACAAGCGCGTATC
CCCAGGGATCCACCTTAACCCTGCCCATCGCCCATGGGGAAGGCCGCTACACCTGTGATCCGGATACCCTCAAGCAGTTG
CAGGATCGAGGGCAGATCGTCTTTCGCTATGCTCCGGTTGCGCCCAACGGCTCTGTGGACAACATCGCCGGCATTTGCGA
TCCCAGCGGTCGGATTCTGGGTTTAATGCCCCACCCTGAGCGGGCAGCAGATCCCGATTTGCCAGGGCAGGATGGGATCC
CCTTCTGGCAGTCGATTTTGCGCAGCTTCGCCGCCTAA

Upstream 100 bases:

>100_bases
CGATTTGGGGTTGATCTGATGGCCATTCCAAAAATACCCCCAACCCCTCTTCCATCCCTCTAATCTGACCATCTTCTTTC
CTCTCACTTAAGGGATCCCA

Downstream 100 bases:

>100_bases
CTCTTCTCCAGGAGAACTCACCCCTGCCTCGGCCCTTGAGACAACACCTGGCGAACTTGATTCACCATCTCCTCGTGATC
CACCACTGGCTTGGCGATAT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MAGVRFGVVVFPGSNCDRDVAWVTRGLLGCPTRLIWHRETDLSELDVVVLPGGFSYGDYLRCGAIARFAPVMGSLKEHAA
RGGYVLGICNGFQILTEAGLLPGALVRNANLHFICDRVGIRVERQDLPWTSAYPQGSTLTLPIAHGEGRYTCDPDTLKQL
QDRGQIVFRYAPVAPNGSVDNIAGICDPSGRILGLMPHPERAADPDLPGQDGIPFWQSILRSFAA

Sequences:

>Translated_225_residues
MAGVRFGVVVFPGSNCDRDVAWVTRGLLGCPTRLIWHRETDLSELDVVVLPGGFSYGDYLRCGAIARFAPVMGSLKEHAA
RGGYVLGICNGFQILTEAGLLPGALVRNANLHFICDRVGIRVERQDLPWTSAYPQGSTLTLPIAHGEGRYTCDPDTLKQL
QDRGQIVFRYAPVAPNGSVDNIAGICDPSGRILGLMPHPERAADPDLPGQDGIPFWQSILRSFAA
>Mature_224_residues
AGVRFGVVVFPGSNCDRDVAWVTRGLLGCPTRLIWHRETDLSELDVVVLPGGFSYGDYLRCGAIARFAPVMGSLKEHAAR
GGYVLGICNGFQILTEAGLLPGALVRNANLHFICDRVGIRVERQDLPWTSAYPQGSTLTLPIAHGEGRYTCDPDTLKQLQ
DRGQIVFRYAPVAPNGSVDNIAGICDPSGRILGLMPHPERAADPDLPGQDGIPFWQSILRSFAA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=213, Percent_Identity=30.0469483568075, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321498, Length=181, Percent_Identity=31.4917127071823, Blast_Score=76, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582111, Length=247, Percent_Identity=28.3400809716599, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24582109, Length=247, Percent_Identity=28.3400809716599, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17137292, Length=247, Percent_Identity=28.3400809716599, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24357; Mature: 24226

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGVRFGVVVFPGSNCDRDVAWVTRGLLGCPTRLIWHRETDLSELDVVVLPGGFSYGDYL
CCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCCCCHH
RCGAIARFAPVMGSLKEHAARGGYVLGICNGFQILTEAGLLPGALVRNANLHFICDRVGI
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCHHHHCCCCEEEEEECCCC
RVERQDLPWTSAYPQGSTLTLPIAHGEGRYTCDPDTLKQLQDRGQIVFRYAPVAPNGSVD
EEECCCCCCCCCCCCCCEEEEEEECCCCCEEECHHHHHHHHHCCCEEEEEECCCCCCCCC
NIAGICDPSGRILGLMPHPERAADPDLPGQDGIPFWQSILRSFAA
CCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AGVRFGVVVFPGSNCDRDVAWVTRGLLGCPTRLIWHRETDLSELDVVVLPGGFSYGDYL
CCEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCCCCHH
RCGAIARFAPVMGSLKEHAARGGYVLGICNGFQILTEAGLLPGALVRNANLHFICDRVGI
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCHHHHCCCCEEEEEECCCC
RVERQDLPWTSAYPQGSTLTLPIAHGEGRYTCDPDTLKQLQDRGQIVFRYAPVAPNGSVD
EEECCCCCCCCCCCCCCEEEEEEECCCCCEEECHHHHHHHHHCCCEEEEEECCCCCCCCC
NIAGICDPSGRILGLMPHPERAADPDLPGQDGIPFWQSILRSFAA
CCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA