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The map label for this gene is ndk [H]

Identifier: 86607769

GI number: 86607769

Start: 286029

End: 286478

Strand: Reverse

Name: ndk [H]

Synonym: CYB_0270

Alternate gene names: 86607769

Gene position: 286478-286029 (Counterclockwise)

Preceding gene: 86607770

Following gene: 86607763

Centisome position: 9.4

GC content: 60.0

Gene sequence:

>450_bases
ATGGAGCGCACCTTTATTGCCATCAAGCCAGACGGCGTGCAGCGGGGGCTGGTGGGCACCATCATCCAGCGCCTGGAGAG
CCGGGGCTACCAATTGGTGGGCCTGAAGCTGGTGCAAGTGAGCCAAGAGCTGGCGGAAGCCCATTACGCCGAACACAAGG
AGCGCCCCTTCTTCCACAGTTTGGTGAAGTTCATTACCTCGGGGCCGGTGGTGGCTATGGTCTGGCAGGGCAAAGGGGTG
ATTGCTGCCGCCCGTAAGCTCATCGGCAAGACCAACCCCCTGGAGGCAGAACCGGGCACCATTCGCGGCGATTTTGGCAT
CGACATTGGCCGCAACCTCATTCACGGCTCCGATGGAGTTGAAACCGCGCAGCGGGAGATCGCCCTTTGGTTCGATGAGT
CGGAATTGGTGAGCTGGACACCGGTTGCCCAAAGCTGGATTTATGAGTAG

Upstream 100 bases:

>100_bases
GGTGGGCGCGTAAAAAGCGCTAATTTTGCTCCCTTGCGCTCGGGATCCCCGATCCGGTACAAGGATAGCGGTGAAGATCT
GTAAAACGAGGGGAGATCCC

Downstream 100 bases:

>100_bases
GTACTTGCTGCAGGCAAGGGGTAGTCGTGTTCGCAGGTTCCAGACCGGGAGTAGTGCAGAGCGCTAGGGCCGTGTTTCGA
ACTGGCTTCGGCTGGCCGCA

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MERTFIAIKPDGVQRGLVGTIIQRLESRGYQLVGLKLVQVSQELAEAHYAEHKERPFFHSLVKFITSGPVVAMVWQGKGV
IAAARKLIGKTNPLEAEPGTIRGDFGIDIGRNLIHGSDGVETAQREIALWFDESELVSWTPVAQSWIYE

Sequences:

>Translated_149_residues
MERTFIAIKPDGVQRGLVGTIIQRLESRGYQLVGLKLVQVSQELAEAHYAEHKERPFFHSLVKFITSGPVVAMVWQGKGV
IAAARKLIGKTNPLEAEPGTIRGDFGIDIGRNLIHGSDGVETAQREIALWFDESELVSWTPVAQSWIYE
>Mature_149_residues
MERTFIAIKPDGVQRGLVGTIIQRLESRGYQLVGLKLVQVSQELAEAHYAEHKERPFFHSLVKFITSGPVVAMVWQGKGV
IAAARKLIGKTNPLEAEPGTIRGDFGIDIGRNLIHGSDGVETAQREIALWFDESELVSWTPVAQSWIYE

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI38045913, Length=149, Percent_Identity=61.744966442953, Blast_Score=206, Evalue=7e-54,
Organism=Homo sapiens, GI4557797, Length=149, Percent_Identity=61.744966442953, Blast_Score=205, Evalue=1e-53,
Organism=Homo sapiens, GI37693993, Length=148, Percent_Identity=63.5135135135135, Blast_Score=204, Evalue=3e-53,
Organism=Homo sapiens, GI66392203, Length=149, Percent_Identity=57.0469798657718, Blast_Score=195, Evalue=1e-50,
Organism=Homo sapiens, GI66392227, Length=149, Percent_Identity=57.0469798657718, Blast_Score=195, Evalue=1e-50,
Organism=Homo sapiens, GI66392205, Length=149, Percent_Identity=57.0469798657718, Blast_Score=195, Evalue=1e-50,
Organism=Homo sapiens, GI4505409, Length=149, Percent_Identity=57.0469798657718, Blast_Score=195, Evalue=1e-50,
Organism=Homo sapiens, GI66392192, Length=149, Percent_Identity=57.0469798657718, Blast_Score=195, Evalue=1e-50,
Organism=Homo sapiens, GI4826862, Length=139, Percent_Identity=56.8345323741007, Blast_Score=177, Evalue=4e-45,
Organism=Homo sapiens, GI37574614, Length=136, Percent_Identity=35.2941176470588, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI7019465, Length=136, Percent_Identity=35.2941176470588, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI5031951, Length=143, Percent_Identity=34.965034965035, Blast_Score=83, Evalue=7e-17,
Organism=Homo sapiens, GI4505413, Length=149, Percent_Identity=32.8859060402685, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788866, Length=140, Percent_Identity=44.2857142857143, Blast_Score=134, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17506807, Length=149, Percent_Identity=57.7181208053691, Blast_Score=187, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17507605, Length=101, Percent_Identity=40.5940594059406, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322783, Length=148, Percent_Identity=58.7837837837838, Blast_Score=196, Evalue=2e-51,
Organism=Drosophila melanogaster, GI45549037, Length=148, Percent_Identity=61.4864864864865, Blast_Score=206, Evalue=3e-54,
Organism=Drosophila melanogaster, GI18860097, Length=136, Percent_Identity=37.5, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564
- InterPro:   IPR023005 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 16570; Mature: 16570

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERTFIAIKPDGVQRGLVGTIIQRLESRGYQLVGLKLVQVSQELAEAHYAEHKERPFFHS
CCCCEEEECCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHH
LVKFITSGPVVAMVWQGKGVIAAARKLIGKTNPLEAEPGTIRGDFGIDIGRNLIHGSDGV
HHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCHHCCCCCCH
ETAQREIALWFDESELVSWTPVAQSWIYE
HHHHHEEEEEECCCCCEEECHHHHHHCCC
>Mature Secondary Structure
MERTFIAIKPDGVQRGLVGTIIQRLESRGYQLVGLKLVQVSQELAEAHYAEHKERPFFHS
CCCCEEEECCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHH
LVKFITSGPVVAMVWQGKGVIAAARKLIGKTNPLEAEPGTIRGDFGIDIGRNLIHGSDGV
HHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCHHCCCCCCH
ETAQREIALWFDESELVSWTPVAQSWIYE
HHHHHEEEEEECCCCCEEECHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA