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The map label for this gene is pilH [H]

Identifier: 86606801

GI number: 86606801

Start: 2173777

End: 2174151

Strand: Reverse

Name: pilH [H]

Synonym: CYA_2161

Alternate gene names: 86606801

Gene position: 2174151-2173777 (Counterclockwise)

Preceding gene: 86606802

Following gene: 86606800

Centisome position: 74.13

GC content: 53.07

Gene sequence:

>375_bases
ATGGTGAAAGTTCTTGTGGTGGAAGATGTGGCCTCGGAGCGACAGCTCATCAGCGATTACCTCCGCTCAGAAGGCTATCA
GGTGGTAGCGGTGGCCAACGCCCAAGAGGCATTGCAGCAGATCCGCAACGACAAACCCGATGTGGTGCTGACGGACTTGG
TCATGGAAGGCATGAGCGGGCTGGAATTGTGCCGCCAAATCAAGAAAAACCCGGAAACCCAAAAGTTGCCCGTTGTGGCC
TGTACTTCTAAAAATCAAGAGCTGGACAAACTCTGGGGCATGAAGCAAGGGATCGATCTTTATCTGACCAAGCCTTTTAC
CCGCGAAGACATTTTGCGGGCCGTGAAATCAGTAGTGCTCAGCGCGAGCTCATGA

Upstream 100 bases:

>100_bases
AGCCCTTTCGGCAGGAAGAATTGCTGCAGATGGTGTTTCGCTATCTCAGCTAGGGATCCCTCTAAAGGTTCGTCGAAAAA
GAGGTAAGGAGATGTCGATC

Downstream 100 bases:

>100_bases
TTTTTGCCACTCCTGTCCTTGCTGAGCTGCGCCTCCAGTTAGGATCCCTGTGATTATCACGAATTGTTCTTAGGAGATGT
CTTAGAATTGGCAGAGCGAG

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MVKVLVVEDVASERQLISDYLRSEGYQVVAVANAQEALQQIRNDKPDVVLTDLVMEGMSGLELCRQIKKNPETQKLPVVA
CTSKNQELDKLWGMKQGIDLYLTKPFTREDILRAVKSVVLSASS

Sequences:

>Translated_124_residues
MVKVLVVEDVASERQLISDYLRSEGYQVVAVANAQEALQQIRNDKPDVVLTDLVMEGMSGLELCRQIKKNPETQKLPVVA
CTSKNQELDKLWGMKQGIDLYLTKPFTREDILRAVKSVVLSASS
>Mature_124_residues
MVKVLVVEDVASERQLISDYLRSEGYQVVAVANAQEALQQIRNDKPDVVLTDLVMEGMSGLELCRQIKKNPETQKLPVVA
CTSKNQELDKLWGMKQGIDLYLTKPFTREDILRAVKSVVLSASS

Specific function: May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=117, Percent_Identity=34.1880341880342, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI1786599, Length=121, Percent_Identity=32.2314049586777, Blast_Score=85, Evalue=2e-18,
Organism=Escherichia coli, GI1789809, Length=117, Percent_Identity=31.6239316239316, Blast_Score=80, Evalue=3e-17,
Organism=Escherichia coli, GI1790860, Length=117, Percent_Identity=31.6239316239316, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1786911, Length=106, Percent_Identity=30.188679245283, Blast_Score=63, Evalue=5e-12,
Organism=Escherichia coli, GI1790863, Length=113, Percent_Identity=30.9734513274336, Blast_Score=61, Evalue=3e-11,
Organism=Escherichia coli, GI1787375, Length=118, Percent_Identity=30.5084745762712, Blast_Score=60, Evalue=5e-11,
Organism=Escherichia coli, GI87082012, Length=116, Percent_Identity=25, Blast_Score=59, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 13864; Mature: 13864

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVLVVEDVASERQLISDYLRSEGYQVVAVANAQEALQQIRNDKPDVVLTDLVMEGMSG
CEEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCEEHHHHHHCCCHH
LELCRQIKKNPETQKLPVVACTSKNQELDKLWGMKQGIDLYLTKPFTREDILRAVKSVVL
HHHHHHHHCCCCCCCCCEEEECCCCCHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHH
SASS
CCCC
>Mature Secondary Structure
MVKVLVVEDVASERQLISDYLRSEGYQVVAVANAQEALQQIRNDKPDVVLTDLVMEGMSG
CEEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCEEHHHHHHCCCHH
LELCRQIKKNPETQKLPVVACTSKNQELDKLWGMKQGIDLYLTKPFTREDILRAVKSVVL
HHHHHHHHCCCCCCCCCEEEECCCCCHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHH
SASS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7908398; 10984043 [H]