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The map label for this gene is patA [H]

Identifier: 86606802

GI number: 86606802

Start: 2174199

End: 2175443

Strand: Reverse

Name: patA [H]

Synonym: CYA_2162

Alternate gene names: 86606802

Gene position: 2175443-2174199 (Counterclockwise)

Preceding gene: 86606803

Following gene: 86606801

Centisome position: 74.18

GC content: 58.15

Gene sequence:

>1245_bases
ATGAACTGTCCCCCCGTCTGTACAGAAGTCTCGGCCCATCTGCTGAACGCAGAGGTCAGCTTCACAGGAGTTGTTCGGTA
TTTCAGTGCCTTGGACAAAGGGGAGGGGCTGGGCACTTGGTCATTGGTGTTTCACCAAGGTCGCCTGGGGTTTGCTCACC
ACAGCTTGGAGCCCTTGGAGCGCTTGGATCGCCACCTGCGTCGGCTCAGCCATCAAGTCTTTTCTCTGACTCGCCAAAAT
TGCCTACGTATCCATCGGCAGGTGGAGGCGCTATTGGCTCAGGAGACTGGGCCTCTACCTGCAGACCTTCTGGGGCTGAG
TTGGATGGTAACGGAGCAACTGCTGCCTTGGGAAGCTGCGCGCAGGTTGAATGCTTGGATCGGCGAGGAGGTGCTGCAAA
ATCTGTTGCTGGTTCCAGGGGGCTTTCAGCAGGAGATCATCCCACTGGACAACGTGCCCACCCTGGGCCAGTGGGATGGG
GGATCCCTGCTCGACCTGATCCAAAAGCGGCTACGGGCATGGCAATCTTTGGGGCCTGAGATCACCTCCCCCTACCAACG
GCCCTACTTTGCCAGCCGGGCCCAGGCAGAACGCCTTCCCGCCGAGCAACAGGAACGGCTAGGCCGGTTACTGAAGGGGT
TTAGCTTCCGCCAGTTGAGCGCCCTTCTCGATCAAGACGACCTCCAGATCGCTCGCCGCCTACATCCTCTGGTCAAAGCC
GGTATCCTTGTCCTGCGGGATCCCCAACCCCCCTTTGATCGGCTGCCCAAAACCTACTCGGCCAAGCTTGAGACAGAATC
ACAGCCCTCAGAAACTCCCACCGTCCCTCTTCACCTGGCCAACGAGCTTGCAGATCTAGGCCCATCTCCCCAGGCCTCGA
AAACCTGGATTGTGGCCTGTATTGACGACAGCGAAGCCATGCTCAGCGAGTTGCAGCGGTTGTTGGAAGGGCACAACCTG
GTCATTCACGCCATCAGCGACTCTTTGAAAGCCCTGATGAAGCTGACCACCCTCAAGCCAGATTTGATCCTGCTGGACGT
GGGTATGCCCAACGTGGATGGCTACCAATTGTGCAGCCTCATCCGCAAATCCTCCGTGTTAAAGGATGTGCCGGTGGTGA
TGGTCACAGGCCACAAAGGTCTGATCGATCGGGTGAAGGCGCGCCTGGCCGGTGCCACCGATTACCTGACCAAGCCCTTT
CGGCAGGAAGAATTGCTGCAGATGGTGTTTCGCTATCTCAGCTAG

Upstream 100 bases:

>100_bases
TTCTGGAAAGCATTTTTTCACCGGCTTGTGGGGTAGCTAAGACTTCAGTCGTGTCATCAACCTCAGCGCAGGAAATTGTC
CGAGCACGTCCTCTCGACCC

Downstream 100 bases:

>100_bases
GGATCCCTCTAAAGGTTCGTCGAAAAAGAGGTAAGGAGATGTCGATCATGGTGAAAGTTCTTGTGGTGGAAGATGTGGCC
TCGGAGCGACAGCTCATCAG

Product: response regulator

Products: NADP; 2 glutathione [C]

Alternate protein names: PAT-1 [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MNCPPVCTEVSAHLLNAEVSFTGVVRYFSALDKGEGLGTWSLVFHQGRLGFAHHSLEPLERLDRHLRRLSHQVFSLTRQN
CLRIHRQVEALLAQETGPLPADLLGLSWMVTEQLLPWEAARRLNAWIGEEVLQNLLLVPGGFQQEIIPLDNVPTLGQWDG
GSLLDLIQKRLRAWQSLGPEITSPYQRPYFASRAQAERLPAEQQERLGRLLKGFSFRQLSALLDQDDLQIARRLHPLVKA
GILVLRDPQPPFDRLPKTYSAKLETESQPSETPTVPLHLANELADLGPSPQASKTWIVACIDDSEAMLSELQRLLEGHNL
VIHAISDSLKALMKLTTLKPDLILLDVGMPNVDGYQLCSLIRKSSVLKDVPVVMVTGHKGLIDRVKARLAGATDYLTKPF
RQEELLQMVFRYLS

Sequences:

>Translated_414_residues
MNCPPVCTEVSAHLLNAEVSFTGVVRYFSALDKGEGLGTWSLVFHQGRLGFAHHSLEPLERLDRHLRRLSHQVFSLTRQN
CLRIHRQVEALLAQETGPLPADLLGLSWMVTEQLLPWEAARRLNAWIGEEVLQNLLLVPGGFQQEIIPLDNVPTLGQWDG
GSLLDLIQKRLRAWQSLGPEITSPYQRPYFASRAQAERLPAEQQERLGRLLKGFSFRQLSALLDQDDLQIARRLHPLVKA
GILVLRDPQPPFDRLPKTYSAKLETESQPSETPTVPLHLANELADLGPSPQASKTWIVACIDDSEAMLSELQRLLEGHNL
VIHAISDSLKALMKLTTLKPDLILLDVGMPNVDGYQLCSLIRKSSVLKDVPVVMVTGHKGLIDRVKARLAGATDYLTKPF
RQEELLQMVFRYLS
>Mature_414_residues
MNCPPVCTEVSAHLLNAEVSFTGVVRYFSALDKGEGLGTWSLVFHQGRLGFAHHSLEPLERLDRHLRRLSHQVFSLTRQN
CLRIHRQVEALLAQETGPLPADLLGLSWMVTEQLLPWEAARRLNAWIGEEVLQNLLLVPGGFQQEIIPLDNVPTLGQWDG
GSLLDLIQKRLRAWQSLGPEITSPYQRPYFASRAQAERLPAEQQERLGRLLKGFSFRQLSALLDQDDLQIARRLHPLVKA
GILVLRDPQPPFDRLPKTYSAKLETESQPSETPTVPLHLANELADLGPSPQASKTWIVACIDDSEAMLSELQRLLEGHNL
VIHAISDSLKALMKLTTLKPDLILLDVGMPNVDGYQLCSLIRKSSVLKDVPVVMVTGHKGLIDRVKARLAGATDYLTKPF
RQEELLQMVFRYLS

Specific function: Controls heterocyst pattern formation. Required for the differentiation of intercalary heterocysts but not for terminal heterocysts [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790299, Length=118, Percent_Identity=33.8983050847458, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786911, Length=108, Percent_Identity=35.1851851851852, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=126, Percent_Identity=32.5396825396825, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786599, Length=92, Percent_Identity=39.1304347826087, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=175, Percent_Identity=28, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 46468; Mature: 46468

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCPPVCTEVSAHLLNAEVSFTGVVRYFSALDKGEGLGTWSLVFHQGRLGFAHHSLEPLE
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCCCHHCCHHHHH
RLDRHLRRLSHQVFSLTRQNCLRIHRQVEALLAQETGPLPADLLGLSWMVTEQLLPWEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHH
RRLNAWIGEEVLQNLLLVPGGFQQEIIPLDNVPTLGQWDGGSLLDLIQKRLRAWQSLGPE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
ITSPYQRPYFASRAQAERLPAEQQERLGRLLKGFSFRQLSALLDQDDLQIARRLHPLVKA
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHH
GILVLRDPQPPFDRLPKTYSAKLETESQPSETPTVPLHLANELADLGPSPQASKTWIVAC
CEEEEECCCCCHHHCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEE
IDDSEAMLSELQRLLEGHNLVIHAISDSLKALMKLTTLKPDLILLDVGMPNVDGYQLCSL
ECCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHH
IRKSSVLKDVPVVMVTGHKGLIDRVKARLAGATDYLTKPFRQEELLQMVFRYLS
HHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MNCPPVCTEVSAHLLNAEVSFTGVVRYFSALDKGEGLGTWSLVFHQGRLGFAHHSLEPLE
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCCCHHCCHHHHH
RLDRHLRRLSHQVFSLTRQNCLRIHRQVEALLAQETGPLPADLLGLSWMVTEQLLPWEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHH
RRLNAWIGEEVLQNLLLVPGGFQQEIIPLDNVPTLGQWDGGSLLDLIQKRLRAWQSLGPE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
ITSPYQRPYFASRAQAERLPAEQQERLGRLLKGFSFRQLSALLDQDDLQIARRLHPLVKA
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHH
GILVLRDPQPPFDRLPKTYSAKLETESQPSETPTVPLHLANELADLGPSPQASKTWIVAC
CEEEEECCCCCHHHCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEE
IDDSEAMLSELQRLLEGHNLVIHAISDSLKALMKLTTLKPDLILLDVGMPNVDGYQLCSL
ECCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHH
IRKSSVLKDVPVVMVTGHKGLIDRVKARLAGATDYLTKPFRQEELLQMVFRYLS
HHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1608976; 11237320; 11759840 [H]