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The map label for this gene is accA

Identifier: 86606792

GI number: 86606792

Start: 2164603

End: 2165586

Strand: Reverse

Name: accA

Synonym: CYA_2152

Alternate gene names: 86606792

Gene position: 2165586-2164603 (Counterclockwise)

Preceding gene: 86606794

Following gene: 86606790

Centisome position: 73.84

GC content: 63.11

Gene sequence:

>984_bases
ATGACCAAGCCCACCGATCGCCTGCTGCTGGAGTTTGAGCAGCCTGTTGCCGCCCTCGAACAGCGCATCCAGGAAATTCG
CGCCTTGGCCGAAGAAAACGACATCGACGCCTCTGAGCAGATTCGCCAACTAGAGGCCAAAGCCGAAGAGCTGCGCCGCG
AGATCTTCAGCCAGCTCACCCCCGTAGAACGGCTGCAGGTGGCCCGCCATCCCCGCCGCCCCACCACCTTGGACTACGTC
CAGACCATCTGCGACGACTGGTTTGAGCTGCACGGGGATCGCCACGGCCAAGACGATCCGGCCATCGTCGGCGGCCTGGC
CAAACTGGGGGATCAGCCGGTGATGATCCTCGGCCACCAAAAAGGCCGCGACACCAAAGACAACATCCACCGCAACTTCG
GCATGCCCAACCCCGCCGGCTACCGCAAAGCCCTGCGGCTGATGGAACATGCCCACCGCTTCGGCCTGCCCCTATTGACC
TTTATCGACACGCCGGGGGCCTACCCAGGGGTTAAGGCAGAAGCCGAGGGCCAGGGGGAAGCGATCGCCACCAACCTGCA
GACCCTGTTTCGGCTGGAGATCCCCATCATCTGCACCGTCATCGGCGAAGGGGGATCCGGGGGGGCTTTGGCCATTGGCA
TTGGGGATCGCATCTTGATGTTTGAGCACGCCGTCTATTCGGTGATCTCGCCGGAAGGCTGTGCGGCCATCCTTTGGAAA
GATGCCAAGAAAGCGCCGCAAGCAGCGGCAGCCCTGCGCATTACCGCCCAAGACCTGCTGCAGCTAGAGGTCATTGACGA
GATCTTGCCGGAGCCGGTTGGCGGCACCCACCGCGCCCCCCTGGAAGCTGCCCAGACGCTGAAAGAAGCTCTCCTGCGGC
ATCTCAAGGAGCTATCTGCTCTGAGCGGGCGGGAGCTGCGGGAGGAGCGCTACCAGAAGTTTCGCCGCATGGGGGCCTTT
CTGGAGCTGGCTCAAGAGAGCTAG

Upstream 100 bases:

>100_bases
GGATGTGAGAAGATCAACTTCCAGCCCTAAGCGGGCTGCCACCCCAGAAGCTGGGGCAAGCTGTCGCAGCCGCCAGATCC
CAACGCGAATGCCGACCGGT

Downstream 100 bases:

>100_bases
ACCGGATCCCTACCAGGTGACCCGATCCCGCAGTTGCTCAATCCGGGCCGGCCCGATGCCCTTGACCCGCTGTAGATCTT
CCAAGGAGGAAAAGGGACGG

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTKPTDRLLLEFEQPVAALEQRIQEIRALAEENDIDASEQIRQLEAKAEELRREIFSQLTPVERLQVARHPRRPTTLDYV
QTICDDWFELHGDRHGQDDPAIVGGLAKLGDQPVMILGHQKGRDTKDNIHRNFGMPNPAGYRKALRLMEHAHRFGLPLLT
FIDTPGAYPGVKAEAEGQGEAIATNLQTLFRLEIPIICTVIGEGGSGGALAIGIGDRILMFEHAVYSVISPEGCAAILWK
DAKKAPQAAAALRITAQDLLQLEVIDEILPEPVGGTHRAPLEAAQTLKEALLRHLKELSALSGRELREERYQKFRRMGAF
LELAQES

Sequences:

>Translated_327_residues
MTKPTDRLLLEFEQPVAALEQRIQEIRALAEENDIDASEQIRQLEAKAEELRREIFSQLTPVERLQVARHPRRPTTLDYV
QTICDDWFELHGDRHGQDDPAIVGGLAKLGDQPVMILGHQKGRDTKDNIHRNFGMPNPAGYRKALRLMEHAHRFGLPLLT
FIDTPGAYPGVKAEAEGQGEAIATNLQTLFRLEIPIICTVIGEGGSGGALAIGIGDRILMFEHAVYSVISPEGCAAILWK
DAKKAPQAAAALRITAQDLLQLEVIDEILPEPVGGTHRAPLEAAQTLKEALLRHLKELSALSGRELREERYQKFRRMGAF
LELAQES
>Mature_326_residues
TKPTDRLLLEFEQPVAALEQRIQEIRALAEENDIDASEQIRQLEAKAEELRREIFSQLTPVERLQVARHPRRPTTLDYVQ
TICDDWFELHGDRHGQDDPAIVGGLAKLGDQPVMILGHQKGRDTKDNIHRNFGMPNPAGYRKALRLMEHAHRFGLPLLTF
IDTPGAYPGVKAEAEGQGEAIATNLQTLFRLEIPIICTVIGEGGSGGALAIGIGDRILMFEHAVYSVISPEGCAAILWKD
AKKAPQAAAALRITAQDLLQLEVIDEILPEPVGGTHRAPLEAAQTLKEALLRHLKELSALSGRELREERYQKFRRMGAFL
ELAQES

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=313, Percent_Identity=55.9105431309904, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 36360; Mature: 36229

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPTDRLLLEFEQPVAALEQRIQEIRALAEENDIDASEQIRQLEAKAEELRREIFSQLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PVERLQVARHPRRPTTLDYVQTICDDWFELHGDRHGQDDPAIVGGLAKLGDQPVMILGHQ
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEECC
KGRDTKDNIHRNFGMPNPAGYRKALRLMEHAHRFGLPLLTFIDTPGAYPGVKAEAEGQGE
CCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCH
AIATNLQTLFRLEIPIICTVIGEGGSGGALAIGIGDRILMFEHAVYSVISPEGCAAILWK
HHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHEEH
DAKKAPQAAAALRITAQDLLQLEVIDEILPEPVGGTHRAPLEAAQTLKEALLRHLKELSA
HHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSGRELREERYQKFRRMGAFLELAQES
HCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKPTDRLLLEFEQPVAALEQRIQEIRALAEENDIDASEQIRQLEAKAEELRREIFSQLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PVERLQVARHPRRPTTLDYVQTICDDWFELHGDRHGQDDPAIVGGLAKLGDQPVMILGHQ
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEECC
KGRDTKDNIHRNFGMPNPAGYRKALRLMEHAHRFGLPLLTFIDTPGAYPGVKAEAEGQGE
CCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCH
AIATNLQTLFRLEIPIICTVIGEGGSGGALAIGIGDRILMFEHAVYSVISPEGCAAILWK
HHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHEEH
DAKKAPQAAAALRITAQDLLQLEVIDEILPEPVGGTHRAPLEAAQTLKEALLRHLKELSA
HHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSGRELREERYQKFRRMGAFLELAQES
HCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]