Click here to switch to the map view.

The map label for this gene is gpmI

Identifier: 86606763

GI number: 86606763

Start: 2136813

End: 2138405

Strand: Reverse

Name: gpmI

Synonym: CYA_2123

Alternate gene names: 86606763

Gene position: 2138405-2136813 (Counterclockwise)

Preceding gene: 86606764

Following gene: 86606760

Centisome position: 72.91

GC content: 63.15

Gene sequence:

>1593_bases
ATGGATGCACAATCGGTGGCACCTGTGGTTCTGGTAATCCTGGATGGCTGGGGTTATCGCGAAGCCCCTGAGGGCAATGC
GGTGCTGGCCGCCCGAACCCCTGTCGTGGACAGCCTATGGGCTACCTACCCCCATACCCTGCTGCAAGCTTCGGGGCGAG
CCGTGGGCCTGCCGTCAGGGCAAATGGGCAACTCAGAAGTGGGCCACCTGACCCTGGGGGCGGGGCGGGTGGTGCCGCAG
GAGTTGGTGCGTATCAGCGACGCCATCGAGACGGGATCCCTTTTTCACGAGCCCCTCTTGGTGGAGGTTTGTCATCGGCT
CAAGGAGCAGGGGGGCCGTTTTCATTTCATTGGCCTCTGCTCTGAGGGGGGGGTTCACTCCCACATCGACCATCTCTACG
GCTTGCTGAAGCTGGCAGCCCAGGCGGGGATCCCTGCCTATGTCCACGCCATCACCGATGGCCGCGATACCTTGCCCCGC
GATGGAGCCAGGGTTCTGGCCGCTCTGGAAAAAGAGCTGCAATGGCTGGGCAGCGGCGTCATCGCCACCCTGAGCGGCCG
CTACTACGCCATGGATCGGGATCGCCGTTGGGAGCGCACCCAGAAGGCCTACGAGATCCTGACGGAAGACGGCCCTGGCT
GTGGCCGCAGCGCCGCCGAGGTGATGGAAGACTTTTACGCCCAGGATATTACCGACGAGTTTATTCCCCCCACTCGCTTG
GCTCCGGGGGCGGTGCAGTCGGGAGATGCGGTCATCTTCTTCAATTTCCGCCCGGATCGCGCCCGCCAGCTTACCCAAGC
TTTTGTCTGTCCCGACTTTTCCGGTTTTCAGCGCCGTCTGATTCCGGATCTCACCTTCATCACCATGACCCAGTACGATC
CGACCTTGCCGGTGCAGGTGCTTTTTAAGCCGCAGAACCTGGATCACCTGCTGGGCCAAGTGGTGAGCGAGGCCGGCCTC
AAGCAATTGCGCATTGCCGAGACGGAAAAGTACGCCCACGTCACCTACTTTTTTAACGGCGGCATTGAGCAGCCCTTTCC
CGGCGAAGATCGCATCTTGGTGCAAAGCCCGCTGGTGGCCACCTACGACCAAATGCCGGAGATGTCAGCGGTGGAGGTGA
CCGACAAAGCCATCGAAGCTATCGCCCGCCGCGAATACAGCCTGGTGGTGCTCAACTACGCCAACCCCGACATGGTGGGC
CACACCGGCAACTTCAAGGCCACGGTGCGGGCGCTGGAGACGGTGGATCGCTGCCTGGGCCGTCTGCTGGCGGCGGTGGT
GGACGTGGGGGGAACCACCTTAATCGTGGCGGATCACGGCAATGCGGAGCTGATGTGGGACGAGCAGGGCAACCCTTGGA
CGGCCCACACCAACAACCCCGTGCCCTGCATCCTGGTGGAGGGGGAAAGGCGCAAGATCCCTGGTCGCGGTGGCGATGTC
AAGCTGCGCTCTGGCGGCACCCTGGCCGATGTCGGCCCCACCCTGCTCGAGATCCTAGGCCTGCCTCAGCCCCCCGAGAT
GACAGGGCAATCTCTTCTGCAGCCGGCAGAATACACCATCCTGCAGCGGCAGCCGGCGCCTGTGGGGCGCTAA

Upstream 100 bases:

>100_bases
TTTCCCCTCACAAGAAAGGTGAAATCTTGAGAGGGAATGGAGGATTCGGTATCGTATTGCCTGGGCTGGTATTATGTCTT
AAAAAACGAGAGGCCATTTC

Downstream 100 bases:

>100_bases
AACCCGCCCTCCCTTACTCGGCTACTGGGATCCCTTCTTGGATTAGCCAAGCCCTCACCTCCTCCCAGCTGCGGTAGAGA
GCTAAAACCTGGGAGTGCTC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MDAQSVAPVVLVILDGWGYREAPEGNAVLAARTPVVDSLWATYPHTLLQASGRAVGLPSGQMGNSEVGHLTLGAGRVVPQ
ELVRISDAIETGSLFHEPLLVEVCHRLKEQGGRFHFIGLCSEGGVHSHIDHLYGLLKLAAQAGIPAYVHAITDGRDTLPR
DGARVLAALEKELQWLGSGVIATLSGRYYAMDRDRRWERTQKAYEILTEDGPGCGRSAAEVMEDFYAQDITDEFIPPTRL
APGAVQSGDAVIFFNFRPDRARQLTQAFVCPDFSGFQRRLIPDLTFITMTQYDPTLPVQVLFKPQNLDHLLGQVVSEAGL
KQLRIAETEKYAHVTYFFNGGIEQPFPGEDRILVQSPLVATYDQMPEMSAVEVTDKAIEAIARREYSLVVLNYANPDMVG
HTGNFKATVRALETVDRCLGRLLAAVVDVGGTTLIVADHGNAELMWDEQGNPWTAHTNNPVPCILVEGERRKIPGRGGDV
KLRSGGTLADVGPTLLEILGLPQPPEMTGQSLLQPAEYTILQRQPAPVGR

Sequences:

>Translated_530_residues
MDAQSVAPVVLVILDGWGYREAPEGNAVLAARTPVVDSLWATYPHTLLQASGRAVGLPSGQMGNSEVGHLTLGAGRVVPQ
ELVRISDAIETGSLFHEPLLVEVCHRLKEQGGRFHFIGLCSEGGVHSHIDHLYGLLKLAAQAGIPAYVHAITDGRDTLPR
DGARVLAALEKELQWLGSGVIATLSGRYYAMDRDRRWERTQKAYEILTEDGPGCGRSAAEVMEDFYAQDITDEFIPPTRL
APGAVQSGDAVIFFNFRPDRARQLTQAFVCPDFSGFQRRLIPDLTFITMTQYDPTLPVQVLFKPQNLDHLLGQVVSEAGL
KQLRIAETEKYAHVTYFFNGGIEQPFPGEDRILVQSPLVATYDQMPEMSAVEVTDKAIEAIARREYSLVVLNYANPDMVG
HTGNFKATVRALETVDRCLGRLLAAVVDVGGTTLIVADHGNAELMWDEQGNPWTAHTNNPVPCILVEGERRKIPGRGGDV
KLRSGGTLADVGPTLLEILGLPQPPEMTGQSLLQPAEYTILQRQPAPVGR
>Mature_530_residues
MDAQSVAPVVLVILDGWGYREAPEGNAVLAARTPVVDSLWATYPHTLLQASGRAVGLPSGQMGNSEVGHLTLGAGRVVPQ
ELVRISDAIETGSLFHEPLLVEVCHRLKEQGGRFHFIGLCSEGGVHSHIDHLYGLLKLAAQAGIPAYVHAITDGRDTLPR
DGARVLAALEKELQWLGSGVIATLSGRYYAMDRDRRWERTQKAYEILTEDGPGCGRSAAEVMEDFYAQDITDEFIPPTRL
APGAVQSGDAVIFFNFRPDRARQLTQAFVCPDFSGFQRRLIPDLTFITMTQYDPTLPVQVLFKPQNLDHLLGQVVSEAGL
KQLRIAETEKYAHVTYFFNGGIEQPFPGEDRILVQSPLVATYDQMPEMSAVEVTDKAIEAIARREYSLVVLNYANPDMVG
HTGNFKATVRALETVDRCLGRLLAAVVDVGGTTLIVADHGNAELMWDEQGNPWTAHTNNPVPCILVEGERRKIPGRGGDV
KLRSGGTLADVGPTLLEILGLPQPPEMTGQSLLQPAEYTILQRQPAPVGR

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=517, Percent_Identity=48.3558994197292, Blast_Score=491, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI32564249, Length=533, Percent_Identity=44.8405253283302, Blast_Score=417, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17507741, Length=533, Percent_Identity=44.8405253283302, Blast_Score=417, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_SYNJA (Q2JSV1)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_475526.1
- ProteinModelPortal:   Q2JSV1
- SMR:   Q2JSV1
- STRING:   Q2JSV1
- GeneID:   3899112
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_2123
- TIGR:   CYA_2123
- eggNOG:   COG0696
- HOGENOM:   HBG613255
- OMA:   DHGNAEL
- ProtClustDB:   PRK05434
- BioCyc:   SSP321327:CYA_2123-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 57880; Mature: 57880

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: ACT_SITE 65-65

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAQSVAPVVLVILDGWGYREAPEGNAVLAARTPVVDSLWATYPHTLLQASGRAVGLPSG
CCCCHHCCEEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEECCCC
QMGNSEVGHLTLGAGRVVPQELVRISDAIETGSLFHEPLLVEVCHRLKEQGGRFHFIGLC
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCHHHHCHHHHHHHHHHHHCCCCEEEEEEE
SEGGVHSHIDHLYGLLKLAAQAGIPAYVHAITDGRDTLPRDGARVLAALEKELQWLGSGV
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCE
IATLSGRYYAMDRDRRWERTQKAYEILTEDGPGCGRSAAEVMEDFYAQDITDEFIPPTRL
EEEECCCEEEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHCCCCCCC
APGAVQSGDAVIFFNFRPDRARQLTQAFVCPDFSGFQRRLIPDLTFITMTQYDPTLPVQV
CCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEEECCCCCCCEEE
LFKPQNLDHLLGQVVSEAGLKQLRIAETEKYAHVTYFFNGGIEQPFPGEDRILVQSPLVA
EECCCCHHHHHHHHHHHHCHHHEEEECCCCEEEEEEEEECCCCCCCCCCCEEEEECCCHH
TYDQMPEMSAVEVTDKAIEAIARREYSLVVLNYANPDMVGHTGNFKATVRALETVDRCLG
HHHCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
RLLAAVVDVGGTTLIVADHGNAELMWDEQGNPWTAHTNNPVPCILVEGERRKIPGRGGDV
HHHHHHHCCCCCEEEEEECCCEEEEECCCCCCEEECCCCCCEEEEECCCCCCCCCCCCCE
KLRSGGTLADVGPTLLEILGLPQPPEMTGQSLLQPAEYTILQRQPAPVGR
EEECCCCCHHCCHHHHHHHCCCCCCCCCHHHHCCCCHHEEEECCCCCCCC
>Mature Secondary Structure
MDAQSVAPVVLVILDGWGYREAPEGNAVLAARTPVVDSLWATYPHTLLQASGRAVGLPSG
CCCCHHCCEEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEECCCC
QMGNSEVGHLTLGAGRVVPQELVRISDAIETGSLFHEPLLVEVCHRLKEQGGRFHFIGLC
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCHHHHCHHHHHHHHHHHHCCCCEEEEEEE
SEGGVHSHIDHLYGLLKLAAQAGIPAYVHAITDGRDTLPRDGARVLAALEKELQWLGSGV
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCE
IATLSGRYYAMDRDRRWERTQKAYEILTEDGPGCGRSAAEVMEDFYAQDITDEFIPPTRL
EEEECCCEEEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHCCCCCCC
APGAVQSGDAVIFFNFRPDRARQLTQAFVCPDFSGFQRRLIPDLTFITMTQYDPTLPVQV
CCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEEECCCCCCCEEE
LFKPQNLDHLLGQVVSEAGLKQLRIAETEKYAHVTYFFNGGIEQPFPGEDRILVQSPLVA
EECCCCHHHHHHHHHHHHCHHHEEEECCCCEEEEEEEEECCCCCCCCCCCEEEEECCCHH
TYDQMPEMSAVEVTDKAIEAIARREYSLVVLNYANPDMVGHTGNFKATVRALETVDRCLG
HHHCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
RLLAAVVDVGGTTLIVADHGNAELMWDEQGNPWTAHTNNPVPCILVEGERRKIPGRGGDV
HHHHHHHCCCCCEEEEEECCCEEEEECCCCCCEEECCCCCCEEEEECCCCCCCCCCCCCE
KLRSGGTLADVGPTLLEILGLPQPPEMTGQSLLQPAEYTILQRQPAPVGR
EEECCCCCHHCCHHHHHHHCCCCCCCCCHHHHCCCCHHEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA