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The map label for this gene is atpA

Identifier: 86606753

GI number: 86606753

Start: 2130468

End: 2131988

Strand: Reverse

Name: atpA

Synonym: CYA_2113

Alternate gene names: 86606753

Gene position: 2131988-2130468 (Counterclockwise)

Preceding gene: 86606754

Following gene: 86606752

Centisome position: 72.7

GC content: 61.28

Gene sequence:

>1521_bases
ATGCCTACAATTCGCCCAGACGAGATCAGCACCATCATCAAGCAACAGATCGAACAGTACAACCAGGAGATGCAGATCTC
CAATGTCGGCACCGTCCTGCAGGTGGGGGACGGCATTGCCCGCATCTACGGCTTGGAGAAGGTGATGGCCAGCGAGCTAC
TGGAGTTCGAGGATGGCACGGTGGGCATTGCCCTCAACCTGGAGGAAGACAACGTCGGCGCGGTGCTGATCGGCTCCGGG
CGCAACATCCAAGAAGGATCTATCGTCAAAGCCACGGGCAGGATTGCCAGCATCCCGGTGGGAGAAGCCCTGCTGGGCCG
CGTGGTGGATCCCCTCTGCAATCCCATCGATGGCAAAGGGCCGATTCACTGCACCGAGACGCGCCTCATTGAGTCGCCGG
CCCCTGGCATCGTCGATCGCCGCTCCGTCTACGAGCCCCTGCAGACTGGCATCACCGCCATCGATGCCCTGATCCCCATC
GGGCGGGGCCAGCGGGAGCTGATCATCGGCGACCGCCAAACCGGCAAGACCACCCTTGCTGTCGACACCATCCTCAACCA
AAAAGGACAGGATGTCATTTGCATCTATGTGGCCATCGGCCAGAAGCAGAGCAATATCGCCCAGGTGGTGAACATCCTGA
GCGAGCGAGGGGCGATGGACTACAGCATTGTGGTGGCTGCCGGCGCCGACAGCCCGGCCCCGCTGCAGTGGCTGGCCCCC
TATTGCGGCGCCACCATCGCCGAGTACTTCATGTACCAGGGCAAGCATACCCTGGTGGTCTACGACGATCTGTCCAAGCA
GGCGGTGGCCTACCGGCAGATGTCGCTGCTGTTGCGGCGCCCACCTGGACGGGAAGCCTACCCAGGAGATGTGTTCTATC
TGCACTCGCGCCTGCTGGAGCGGGCCGCCAAGCTGAACAGCCGGCTGGGCGAGGGATCCATGACGGCGCTGCCGATTGTG
GAAACCCAGGCCAACGACGTGTCGGCCTATATTCCCACCAACGTTATCTCCATTACCGATGGGCAGATCTTCCTGGAGTC
GGATCTGTTCAACGCCGGCATTCGCCCGGCCATCAACGTCGGCATCTCTGTCAGCCGCGTCGGCTCGGCAGCCCAGACCA
AGGCGATGAAGAAAGTGGCCGGCTCGATCAAGGTGGAACTGGCGCAATATCGCGACCTGGAAGCCTTTGCCCAATTTGCC
TCCGACCTGGACGAAGCTACACAGAAGCAACTGGCCCGCGGCCAACGGCTGCAGGAGATCCTCAAGCAGCCGCAGTACTC
GCCCCTGTCTTTGGATCAGCAGGTGGCCATCATCTACGCCGGGACGCGGGGGTATTTGGACGACATTCCGGTGGAGAAAG
TCTCCAGCTTTAAGCAGGGCCTGCTGTCCTACTTGGGCACCGCCCATCCCAAGTATGGCGAGATCGTTCTCTCCACCAAG
CAGCTTACCGACGAGGCGGAAGAGATCTTGAAAACCGCCATCGCGGAGTTCAAGCAAAGCTTCCTGGCCAAGGCGGCCTA
G

Upstream 100 bases:

>100_bases
TGCGCGGCCAGTTGCGCCGGCTGGCGCTGCAGTTAGCCTAGATTGGCCGAGCGTTTTTCCTTAATTTTGGATCCCTTCCC
ATTCCCTCGAGAGGACTGCC

Downstream 100 bases:

>100_bases
TTGCCGGGGATCCCCATCCAGTGACCACAGCAGAGAGGATCGGTTATGGCAAACCTAAAGCGGATTCGCGACCGCATCAA
GGCGGTGAAGAACACCCGCA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MPTIRPDEISTIIKQQIEQYNQEMQISNVGTVLQVGDGIARIYGLEKVMASELLEFEDGTVGIALNLEEDNVGAVLIGSG
RNIQEGSIVKATGRIASIPVGEALLGRVVDPLCNPIDGKGPIHCTETRLIESPAPGIVDRRSVYEPLQTGITAIDALIPI
GRGQRELIIGDRQTGKTTLAVDTILNQKGQDVICIYVAIGQKQSNIAQVVNILSERGAMDYSIVVAAGADSPAPLQWLAP
YCGATIAEYFMYQGKHTLVVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNSRLGEGSMTALPIV
ETQANDVSAYIPTNVISITDGQIFLESDLFNAGIRPAINVGISVSRVGSAAQTKAMKKVAGSIKVELAQYRDLEAFAQFA
SDLDEATQKQLARGQRLQEILKQPQYSPLSLDQQVAIIYAGTRGYLDDIPVEKVSSFKQGLLSYLGTAHPKYGEIVLSTK
QLTDEAEEILKTAIAEFKQSFLAKAA

Sequences:

>Translated_506_residues
MPTIRPDEISTIIKQQIEQYNQEMQISNVGTVLQVGDGIARIYGLEKVMASELLEFEDGTVGIALNLEEDNVGAVLIGSG
RNIQEGSIVKATGRIASIPVGEALLGRVVDPLCNPIDGKGPIHCTETRLIESPAPGIVDRRSVYEPLQTGITAIDALIPI
GRGQRELIIGDRQTGKTTLAVDTILNQKGQDVICIYVAIGQKQSNIAQVVNILSERGAMDYSIVVAAGADSPAPLQWLAP
YCGATIAEYFMYQGKHTLVVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNSRLGEGSMTALPIV
ETQANDVSAYIPTNVISITDGQIFLESDLFNAGIRPAINVGISVSRVGSAAQTKAMKKVAGSIKVELAQYRDLEAFAQFA
SDLDEATQKQLARGQRLQEILKQPQYSPLSLDQQVAIIYAGTRGYLDDIPVEKVSSFKQGLLSYLGTAHPKYGEIVLSTK
QLTDEAEEILKTAIAEFKQSFLAKAA
>Mature_505_residues
PTIRPDEISTIIKQQIEQYNQEMQISNVGTVLQVGDGIARIYGLEKVMASELLEFEDGTVGIALNLEEDNVGAVLIGSGR
NIQEGSIVKATGRIASIPVGEALLGRVVDPLCNPIDGKGPIHCTETRLIESPAPGIVDRRSVYEPLQTGITAIDALIPIG
RGQRELIIGDRQTGKTTLAVDTILNQKGQDVICIYVAIGQKQSNIAQVVNILSERGAMDYSIVVAAGADSPAPLQWLAPY
CGATIAEYFMYQGKHTLVVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNSRLGEGSMTALPIVE
TQANDVSAYIPTNVISITDGQIFLESDLFNAGIRPAINVGISVSRVGSAAQTKAMKKVAGSIKVELAQYRDLEAFAQFAS
DLDEATQKQLARGQRLQEILKQPQYSPLSLDQQVAIIYAGTRGYLDDIPVEKVSSFKQGLLSYLGTAHPKYGEIVLSTKQ
LTDEAEEILKTAIAEFKQSFLAKAA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=504, Percent_Identity=60.1190476190476, Blast_Score=617, Evalue=1e-177,
Organism=Homo sapiens, GI4757810, Length=504, Percent_Identity=60.1190476190476, Blast_Score=617, Evalue=1e-177,
Organism=Homo sapiens, GI19913428, Length=303, Percent_Identity=31.3531353135314, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI19913426, Length=318, Percent_Identity=30.188679245283, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI32189394, Length=409, Percent_Identity=24.6943765281174, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI19913424, Length=248, Percent_Identity=28.2258064516129, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790172, Length=504, Percent_Identity=56.7460317460317, Blast_Score=571, Evalue=1e-164,
Organism=Escherichia coli, GI1788251, Length=334, Percent_Identity=32.0359281437126, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1790170, Length=468, Percent_Identity=23.0769230769231, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=58.7649402390438, Blast_Score=610, Evalue=1e-175,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=58.7649402390438, Blast_Score=610, Evalue=1e-175,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=54.7808764940239, Blast_Score=557, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI17570191, Length=308, Percent_Identity=31.1688311688312, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17510931, Length=299, Percent_Identity=31.1036789297659, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=440, Percent_Identity=24.3181818181818, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71988068, Length=74, Percent_Identity=41.8918918918919, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=253, Percent_Identity=28.4584980237154, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=58, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=505, Percent_Identity=59.6039603960396, Blast_Score=611, Evalue=1e-175,
Organism=Saccharomyces cerevisiae, GI6319603, Length=426, Percent_Identity=29.5774647887324, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6322581, Length=406, Percent_Identity=25.615763546798, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24658560, Length=507, Percent_Identity=59.3688362919132, Blast_Score=608, Evalue=1e-174,
Organism=Drosophila melanogaster, GI281361666, Length=342, Percent_Identity=29.5321637426901, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24646341, Length=342, Percent_Identity=29.5321637426901, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136796, Length=342, Percent_Identity=29.5321637426901, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24638766, Length=402, Percent_Identity=25.8706467661692, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI28574560, Length=440, Percent_Identity=26.5909090909091, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24583992, Length=415, Percent_Identity=25.7831325301205, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24583988, Length=297, Percent_Identity=26.9360269360269, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24583986, Length=297, Percent_Identity=26.9360269360269, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24583984, Length=297, Percent_Identity=26.9360269360269, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI20129479, Length=317, Percent_Identity=25.8675078864353, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_SYNJA (Q2JSW1)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_475516.1
- ProteinModelPortal:   Q2JSW1
- SMR:   Q2JSW1
- STRING:   Q2JSW1
- GeneID:   3899160
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_2113
- TIGR:   CYA_2113
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- ProtClustDB:   PRK09281
- BioCyc:   SSP321327:CYA_2113-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54878; Mature: 54746

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTIRPDEISTIIKQQIEQYNQEMQISNVGTVLQVGDGIARIYGLEKVMASELLEFEDGT
CCCCCHHHHHHHHHHHHHHHHHHEEHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCE
VGIALNLEEDNVGAVLIGSGRNIQEGSIVKATGRIASIPVGEALLGRVVDPLCNPIDGKG
EEEEEEECCCCCCEEEEECCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHHCCCCCCCC
PIHCTETRLIESPAPGIVDRRSVYEPLQTGITAIDALIPIGRGQRELIIGDRQTGKTTLA
CEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEE
VDTILNQKGQDVICIYVAIGQKQSNIAQVVNILSERGAMDYSIVVAAGADSPAPLQWLAP
HHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHH
YCGATIAEYFMYQGKHTLVVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLE
HHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLNSRLGEGSMTALPIVETQANDVSAYIPTNVISITDGQIFLESDLFNAGIRPAINV
HHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCHHCCCCCCHHHC
GISVSRVGSAAQTKAMKKVAGSIKVELAQYRDLEAFAQFASDLDEATQKQLARGQRLQEI
CEEHHHCCCHHHHHHHHHHHHHHEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQPQYSPLSLDQQVAIIYAGTRGYLDDIPVEKVSSFKQGLLSYLGTAHPKYGEIVLSTK
HHCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEHH
QLTDEAEEILKTAIAEFKQSFLAKAA
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PTIRPDEISTIIKQQIEQYNQEMQISNVGTVLQVGDGIARIYGLEKVMASELLEFEDGT
CCCCHHHHHHHHHHHHHHHHHHEEHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCE
VGIALNLEEDNVGAVLIGSGRNIQEGSIVKATGRIASIPVGEALLGRVVDPLCNPIDGKG
EEEEEEECCCCCCEEEEECCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHHCCCCCCCC
PIHCTETRLIESPAPGIVDRRSVYEPLQTGITAIDALIPIGRGQRELIIGDRQTGKTTLA
CEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEE
VDTILNQKGQDVICIYVAIGQKQSNIAQVVNILSERGAMDYSIVVAAGADSPAPLQWLAP
HHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHH
YCGATIAEYFMYQGKHTLVVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLE
HHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLNSRLGEGSMTALPIVETQANDVSAYIPTNVISITDGQIFLESDLFNAGIRPAINV
HHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCHHCCCCCCHHHC
GISVSRVGSAAQTKAMKKVAGSIKVELAQYRDLEAFAQFASDLDEATQKQLARGQRLQEI
CEEHHHCCCHHHHHHHHHHHHHHEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQPQYSPLSLDQQVAIIYAGTRGYLDDIPVEKVSSFKQGLLSYLGTAHPKYGEIVLSTK
HHCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEHH
QLTDEAEEILKTAIAEFKQSFLAKAA
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA