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The map label for this gene is nucH [H]

Identifier: 86606586

GI number: 86606586

Start: 1951110

End: 1951634

Strand: Reverse

Name: nucH [H]

Synonym: CYA_1940

Alternate gene names: 86606586

Gene position: 1951634-1951110 (Counterclockwise)

Preceding gene: 86606587

Following gene: 86606585

Centisome position: 66.55

GC content: 61.14

Gene sequence:

>525_bases
ATGTTCCGGCGTATTGCTGTTGGCTCTGCGGTGTTGGGATGGCTCTTGGCCCTGCCCGGCCACGGCTTTGGGGAGCGGCG
GGTTGTGCCCGATACCCCCTTCTACTTCGACAACCACTACTTTGATCGCTACCCGGATGCAGTGGTGGTGAGCGTGGTCA
ACGGTGACACGCTGGTGGTGCAGGTCGAAGGGGAACAGAAATTGCGCCTCATCCGCCTGGCCGGGATCCAAGGTCTTAGC
CCGGAGGAGGATCCCTTTTACCAGCAAGCAATTGAGCTGATGCGGGAGCGCATCCTGCACCGCACCGTCAAGCTGGAAGG
GGATAAGCTGCTGCGCAATGTGGATGCCACCGGCTTGGTGGAGGCCTACGTCTGGCTGGAGGGCCAGCAGATGAACGCTA
TGCTGGTGCGCAACGGCCTGGCCCGCATCGCTCCCTACAGCCACAACATCAAATACGACAGCTACTTCGGTGGCCTGCAA
AAAAGAGCCCGCCAAGAGCGCCTCGGCATCTGGAGCCGCCTCTGA

Upstream 100 bases:

>100_bases
GGGGTTGTCTTCCAGGCAGTTGCCGCTACCATTACGCCTTAGGTGTTGCCGACAAACGCTCCCTGGGGGAGGGGAGCCGC
TATCCGCAAGGGGGAAAGAC

Downstream 100 bases:

>100_bases
CGCCTTGGATAGCTCTAGACTGGGTTTACTGGGCACTCTGAGAGACGTCTGCCTGCTTTGAGGGTTAAATCCACTCCGGC
TTCCCGGGATCCCAATCGCT

Product: thermonuclease

Products: NA

Alternate protein names: TNase; Micrococcal nuclease; Staphylococcal nuclease [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MFRRIAVGSAVLGWLLALPGHGFGERRVVPDTPFYFDNHYFDRYPDAVVVSVVNGDTLVVQVEGEQKLRLIRLAGIQGLS
PEEDPFYQQAIELMRERILHRTVKLEGDKLLRNVDATGLVEAYVWLEGQQMNAMLVRNGLARIAPYSHNIKYDSYFGGLQ
KRARQERLGIWSRL

Sequences:

>Translated_174_residues
MFRRIAVGSAVLGWLLALPGHGFGERRVVPDTPFYFDNHYFDRYPDAVVVSVVNGDTLVVQVEGEQKLRLIRLAGIQGLS
PEEDPFYQQAIELMRERILHRTVKLEGDKLLRNVDATGLVEAYVWLEGQQMNAMLVRNGLARIAPYSHNIKYDSYFGGLQ
KRARQERLGIWSRL
>Mature_174_residues
MFRRIAVGSAVLGWLLALPGHGFGERRVVPDTPFYFDNHYFDRYPDAVVVSVVNGDTLVVQVEGEQKLRLIRLAGIQGLS
PEEDPFYQQAIELMRERILHRTVKLEGDKLLRNVDATGLVEAYVWLEGQQMNAMLVRNGLARIAPYSHNIKYDSYFGGLQ
KRARQERLGIWSRL

Specific function: Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5'-position of the phosphodiester bond [H]

COG id: COG1525

COG function: function code L; Micrococcal nuclease (thermonuclease) homologs

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thermonuclease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016071
- InterPro:   IPR006021
- InterPro:   IPR002071 [H]

Pfam domain/function: PF00565 SNase [H]

EC number: =3.1.31.1 [H]

Molecular weight: Translated: 19915; Mature: 19915

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS50830 TNASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRRIAVGSAVLGWLLALPGHGFGERRVVPDTPFYFDNHYFDRYPDAVVVSVVNGDTLVV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCEEEE
QVEGEQKLRLIRLAGIQGLSPEEDPFYQQAIELMRERILHRTVKLEGDKLLRNVDATGLV
EECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHE
EAYVWLEGQQMNAMLVRNGLARIAPYSHNIKYDSYFGGLQKRARQERLGIWSRL
EEEEEECCCCCHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFRRIAVGSAVLGWLLALPGHGFGERRVVPDTPFYFDNHYFDRYPDAVVVSVVNGDTLVV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCEEEE
QVEGEQKLRLIRLAGIQGLSPEEDPFYQQAIELMRERILHRTVKLEGDKLLRNVDATGLV
EECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHE
EAYVWLEGQQMNAMLVRNGLARIAPYSHNIKYDSYFGGLQKRARQERLGIWSRL
EEEEEECCCCCHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045422 [H]