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The map label for this gene is phoR [H]

Identifier: 86606312

GI number: 86606312

Start: 1652449

End: 1653678

Strand: Reverse

Name: phoR [H]

Synonym: CYA_1656

Alternate gene names: 86606312

Gene position: 1653678-1652449 (Counterclockwise)

Preceding gene: 86606313

Following gene: 86606310

Centisome position: 56.39

GC content: 62.28

Gene sequence:

>1230_bases
ATGCAGAGGCTTGAGAGCAACCTTTCGGCTGGATCCGTTCCTCAGACCGGAACGAGCTCTGCTGCGGCAGAGAAGCGGCC
TCTCCTCCTCATTGCCGACGATGATCCCAGCCAGCGGCTTTTGACTCGCTACGCCCTGGAGCGGGAGGGCTACCAACTCG
TGGAAGCGGACAGCGGCTTGGCGTGTCTAGAAGCTGCAAGCCGCTATCAGCCGGACATGGTGCTCCTCGATGCGGTGATG
CCGGATCTGGATGGGTTTGAGTGCTGCCGCCGCCTCCACGCCCAAAACCCGGACTTGCCGATTTTAATCGTCACGGCTTT
GGAAGACGAAACCTTTGTCAACGAGGCCTTTGCAGCCGGCGCCAGCGACTACATCCCCAAGCCCATCCACTGGTCGGTTT
TGAAGCGGCGGCTGCGCCACTTGCTGCAAGCCAACCAGGCCCAGCGCCGTCTGCAGCAGCTTAACCAGGAACTGGAAGCC
AAGGTACAGGAGCGCACCGCCCAACTGGCCTGCCAGGTGGCAGATCTGGAGCAGCTCAACCGCCTCAAAGACCACTTTTT
GGCCACCGTCTCCCACGAGCTGTGCACCCCCCTGACCAAGATCAAGCTGGCCCTGGAACTCCTGCGCCGCACCCCCCTCA
ACGAGAAGCAGCGGCAATACCATGACATTGCCCTGCAGGAGTGCGAGGCCGAAATCCAGCTCATCAACCGCCTATTGGAT
CTGCAGGGCCTGGAAGGGAAAGACCTGGGCTCTGCCGTTGCAGCTATTGACCTGCCCCACCTCTGGCACAGCTTGATCGA
GTCGGTGCAGCAATGCACCCAGGCCCGCTCCCTCACGCTGCAGGTGGGGGATCTGCCCCCCTCCCCCTGGCGGTTTTACA
GCCATCCGCAGCTCCTGACCCAGATCCTCAAAGAGCTGCTGGACAACGCCTGCAAGTTCACCCAGCCAGGTGGCACGATT
CGTCTAGAGGTTCAGCCAATCCCTGAAGGGGTTGAGTTCAGGATCGGCAACACCGCTCAGATCCCGCCCGACCAGTTGCC
CCGCCTGTTCGAGCGCTTTTATCGGGTGCCCACTGCGGATCCCTGGGCCCAGCCGGGCAGCGGCCTGGGGCTGGCCTTGG
TGAAGCAATGGGTGGAGCGCCTCCAGGGTCACATTCGAGTAACCAGCGAGGCGGGGTGGACATGTTTCCTGCTGCGCCTG
CCCAGCCTAAAGCCCTCTGGCAGGACGTGA

Upstream 100 bases:

>100_bases
ATAGAGCAGGCCTTCCAGCGGTTGGAAGCCGAGTACCAGCGGGTTATCCTCGAATTATCGGCTAGCGCGCCAGGACCGCT
TCTTTCTTCTCCAGGGGCCC

Downstream 100 bases:

>100_bases
TCAGTGGCCGACGGCAGCGGCGGTTTCGGCAGTGGCAAAGGAAGTGCCGCAGCCGCAGCTAGCCACCGCATTGGGGTTCT
TGAAGCGGAAGCCGCCCCCC

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MQRLESNLSAGSVPQTGTSSAAAEKRPLLLIADDDPSQRLLTRYALEREGYQLVEADSGLACLEAASRYQPDMVLLDAVM
PDLDGFECCRRLHAQNPDLPILIVTALEDETFVNEAFAAGASDYIPKPIHWSVLKRRLRHLLQANQAQRRLQQLNQELEA
KVQERTAQLACQVADLEQLNRLKDHFLATVSHELCTPLTKIKLALELLRRTPLNEKQRQYHDIALQECEAEIQLINRLLD
LQGLEGKDLGSAVAAIDLPHLWHSLIESVQQCTQARSLTLQVGDLPPSPWRFYSHPQLLTQILKELLDNACKFTQPGGTI
RLEVQPIPEGVEFRIGNTAQIPPDQLPRLFERFYRVPTADPWAQPGSGLGLALVKQWVERLQGHIRVTSEAGWTCFLLRL
PSLKPSGRT

Sequences:

>Translated_409_residues
MQRLESNLSAGSVPQTGTSSAAAEKRPLLLIADDDPSQRLLTRYALEREGYQLVEADSGLACLEAASRYQPDMVLLDAVM
PDLDGFECCRRLHAQNPDLPILIVTALEDETFVNEAFAAGASDYIPKPIHWSVLKRRLRHLLQANQAQRRLQQLNQELEA
KVQERTAQLACQVADLEQLNRLKDHFLATVSHELCTPLTKIKLALELLRRTPLNEKQRQYHDIALQECEAEIQLINRLLD
LQGLEGKDLGSAVAAIDLPHLWHSLIESVQQCTQARSLTLQVGDLPPSPWRFYSHPQLLTQILKELLDNACKFTQPGGTI
RLEVQPIPEGVEFRIGNTAQIPPDQLPRLFERFYRVPTADPWAQPGSGLGLALVKQWVERLQGHIRVTSEAGWTCFLLRL
PSLKPSGRT
>Mature_409_residues
MQRLESNLSAGSVPQTGTSSAAAEKRPLLLIADDDPSQRLLTRYALEREGYQLVEADSGLACLEAASRYQPDMVLLDAVM
PDLDGFECCRRLHAQNPDLPILIVTALEDETFVNEAFAAGASDYIPKPIHWSVLKRRLRHLLQANQAQRRLQQLNQELEA
KVQERTAQLACQVADLEQLNRLKDHFLATVSHELCTPLTKIKLALELLRRTPLNEKQRQYHDIALQECEAEIQLINRLLD
LQGLEGKDLGSAVAAIDLPHLWHSLIESVQQCTQARSLTLQVGDLPPSPWRFYSHPQLLTQILKELLDNACKFTQPGGTI
RLEVQPIPEGVEFRIGNTAQIPPDQLPRLFERFYRVPTADPWAQPGSGLGLALVKQWVERLQGHIRVTSEAGWTCFLLRL
PSLKPSGRT

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=244, Percent_Identity=29.5081967213115, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790861, Length=220, Percent_Identity=32.7272727272727, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=29.4820717131474, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=28.448275862069, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788713, Length=226, Percent_Identity=28.7610619469027, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=30, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790346, Length=269, Percent_Identity=28.2527881040892, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=262, Percent_Identity=28.6259541984733, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994928, Length=221, Percent_Identity=28.5067873303167, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789149, Length=282, Percent_Identity=25.531914893617, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790860, Length=100, Percent_Identity=38, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=27.9475982532751, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=135, Percent_Identity=32.5925925925926, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=29.0909090909091, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786911, Length=120, Percent_Identity=37.5, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788550, Length=135, Percent_Identity=27.4074074074074, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786784, Length=120, Percent_Identity=32.5, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=34.2105263157895, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789809, Length=120, Percent_Identity=34.1666666666667, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787375, Length=119, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788394, Length=171, Percent_Identity=31.5789473684211, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45973; Mature: 45973

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRLESNLSAGSVPQTGTSSAAAEKRPLLLIADDDPSQRLLTRYALEREGYQLVEADSGL
CCCHHCCCCCCCCCCCCCCCCHHCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCH
ACLEAASRYQPDMVLLDAVMPDLDGFECCRRLHAQNPDLPILIVTALEDETFVNEAFAAG
HHHHHHHHCCCCCEEHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCC
ASDYIPKPIHWSVLKRRLRHLLQANQAQRRLQQLNQELEAKVQERTAQLACQVADLEQLN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLKDHFLATVSHELCTPLTKIKLALELLRRTPLNEKQRQYHDIALQECEAEIQLINRLLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LQGLEGKDLGSAVAAIDLPHLWHSLIESVQQCTQARSLTLQVGDLPPSPWRFYSHPQLLT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHH
QILKELLDNACKFTQPGGTIRLEVQPIPEGVEFRIGNTAQIPPDQLPRLFERFYRVPTAD
HHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCC
PWAQPGSGLGLALVKQWVERLQGHIRVTSEAGWTCFLLRLPSLKPSGRT
CCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MQRLESNLSAGSVPQTGTSSAAAEKRPLLLIADDDPSQRLLTRYALEREGYQLVEADSGL
CCCHHCCCCCCCCCCCCCCCCHHCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCH
ACLEAASRYQPDMVLLDAVMPDLDGFECCRRLHAQNPDLPILIVTALEDETFVNEAFAAG
HHHHHHHHCCCCCEEHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCC
ASDYIPKPIHWSVLKRRLRHLLQANQAQRRLQQLNQELEAKVQERTAQLACQVADLEQLN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLKDHFLATVSHELCTPLTKIKLALELLRRTPLNEKQRQYHDIALQECEAEIQLINRLLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LQGLEGKDLGSAVAAIDLPHLWHSLIESVQQCTQARSLTLQVGDLPPSPWRFYSHPQLLT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHH
QILKELLDNACKFTQPGGTIRLEVQPIPEGVEFRIGNTAQIPPDQLPRLFERFYRVPTAD
HHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCC
PWAQPGSGLGLALVKQWVERLQGHIRVTSEAGWTCFLLRLPSLKPSGRT
CCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]