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The map label for this gene is alr

Identifier: 86606130

GI number: 86606130

Start: 1467548

End: 1468837

Strand: Reverse

Name: alr

Synonym: CYA_1462

Alternate gene names: 86606130

Gene position: 1468837-1467548 (Counterclockwise)

Preceding gene: 86606131

Following gene: 86606129

Centisome position: 50.08

GC content: 65.97

Gene sequence:

>1290_bases
GTGGATCACACGCCGGACGACGCTTCTGCGCTGGCGACGGCAGGGCATAGCCCCCTGGCCACGGCGTCCGCCTCGTGGAC
CCAGAGCCAGGGATCCCAGGGAGCGGATCCCGTCGGCGAGACGGGGTTCTGGCCGGATTTCAACCCAGAGCTGGAGCTGC
TGACCAGCCGGGCATGGGTGGAAATTGACGCAGCCCAATTGCGAGAAAATCTGCGTCTGTTGCAGGCGCGCCTGTCGCCA
GACACTGAGATCTGGGCAGTGGTCAAGGCCAATGCCTACGGCCATGGAGCTCGCTTGGTGGCTCCCATAGCCCTCGCTGC
CGGTGCCAAGGGGTTGTGTGTGGCCACCCTGGCAGAAGGGATCGAGCTGCGGCAGGCCGGCCTCCAGGCCCCGATTTTGG
TGTTGGGGGCTTTGAATACCTGGGCCGAGCTGCAGCAGGCCATGGCTGCGCGGCTGGAGGTCAGCCTCACCCGGGCCGAG
CAGATCCCCGTGATGCGCCAGGTGGCCCGTTGGGCCGGGCGGCCTGTTCCTGTCCACGTCAACGTCGATACGGGCATGAC
CCGCCTGGGGATTCCCTGGCAAGAGGCCGCCGCCGTGTGGGGGCAGATCTGCCGGATCCCCGAGCTGGAAGGCTGTAGCC
TGTTTTCCCACTTCGCAACGGCAGATGAGCCCGATTCTCCGGTGATGGCCCAGCAAGAGGCCCGCTTCGCCCAGGTGGTG
GAGCAGATCCGCCAGGCCGGGGATCCCCTGCCCCCCCTGCATCTGGATAACTCCGCCGGCGCCCTAATCCATCTCCACTA
TCCCCGCGTGCGGTTGGGGCTGGCCCTCTACGGCTTGTCTCCTGCCCCGCACCTGCAGGTGCCGGGGTTGCGGCCGATCC
TGCGCCTCAAAGCGCGGTTGACCCACATCCAAACCGTACCCGCCCACACCGGCGTCAGCTATGGCCATCGCTACGTCACT
TCTCGCCCCAGTCGCATTGCCACACTGGCCATCGGCTATGCCGACGGGATCCCACGGCGGCTTTCCGGCTGGCTGCGGGG
GTGGGTGCGCGGCAGCCTGATCCAGCAGGTGGGCACGATCACGATGGATCAGTGCATGTGGGATGTCACCGAGAGGCCGG
ATATTCAGGTGGGTGATGTGGTGGAGCTGCTGGGCCCCCATCTGGCGAGTGCGGGTTTCTCAATCCAGGATTGGGCGGAT
CAGTTGGGCACCATTTCCTATGAACTGCTGTGCGGACTTTCTGCCCGCCTGCCGAGAGTGCTGGTCAACGTGCTCGGGGA
AGCTAGCTGA

Upstream 100 bases:

>100_bases
GTGGCCGGGATCCCGGAAGTGCCGCTGCTGTGGATGGCGCCCGGGTGGACTTTGCGCTAAACCTGACAGTGATCATAGGC
TTGGTGTGAGGGGTGAAGCT

Downstream 100 bases:

>100_bases
CGTTGACGCTATGGCACGTTTTTGTTGGGCGGTTTATGGTAGCAGCAAATGCAGGCGAGGTTTTAAGCGTGGGTTCGGAT
CCCTACCTCCCCCCTCAATT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MDHTPDDASALATAGHSPLATASASWTQSQGSQGADPVGETGFWPDFNPELELLTSRAWVEIDAAQLRENLRLLQARLSP
DTEIWAVVKANAYGHGARLVAPIALAAGAKGLCVATLAEGIELRQAGLQAPILVLGALNTWAELQQAMAARLEVSLTRAE
QIPVMRQVARWAGRPVPVHVNVDTGMTRLGIPWQEAAAVWGQICRIPELEGCSLFSHFATADEPDSPVMAQQEARFAQVV
EQIRQAGDPLPPLHLDNSAGALIHLHYPRVRLGLALYGLSPAPHLQVPGLRPILRLKARLTHIQTVPAHTGVSYGHRYVT
SRPSRIATLAIGYADGIPRRLSGWLRGWVRGSLIQQVGTITMDQCMWDVTERPDIQVGDVVELLGPHLASAGFSIQDWAD
QLGTISYELLCGLSARLPRVLVNVLGEAS

Sequences:

>Translated_429_residues
MDHTPDDASALATAGHSPLATASASWTQSQGSQGADPVGETGFWPDFNPELELLTSRAWVEIDAAQLRENLRLLQARLSP
DTEIWAVVKANAYGHGARLVAPIALAAGAKGLCVATLAEGIELRQAGLQAPILVLGALNTWAELQQAMAARLEVSLTRAE
QIPVMRQVARWAGRPVPVHVNVDTGMTRLGIPWQEAAAVWGQICRIPELEGCSLFSHFATADEPDSPVMAQQEARFAQVV
EQIRQAGDPLPPLHLDNSAGALIHLHYPRVRLGLALYGLSPAPHLQVPGLRPILRLKARLTHIQTVPAHTGVSYGHRYVT
SRPSRIATLAIGYADGIPRRLSGWLRGWVRGSLIQQVGTITMDQCMWDVTERPDIQVGDVVELLGPHLASAGFSIQDWAD
QLGTISYELLCGLSARLPRVLVNVLGEAS
>Mature_429_residues
MDHTPDDASALATAGHSPLATASASWTQSQGSQGADPVGETGFWPDFNPELELLTSRAWVEIDAAQLRENLRLLQARLSP
DTEIWAVVKANAYGHGARLVAPIALAAGAKGLCVATLAEGIELRQAGLQAPILVLGALNTWAELQQAMAARLEVSLTRAE
QIPVMRQVARWAGRPVPVHVNVDTGMTRLGIPWQEAAAVWGQICRIPELEGCSLFSHFATADEPDSPVMAQQEARFAQVV
EQIRQAGDPLPPLHLDNSAGALIHLHYPRVRLGLALYGLSPAPHLQVPGLRPILRLKARLTHIQTVPAHTGVSYGHRYVT
SRPSRIATLAIGYADGIPRRLSGWLRGWVRGSLIQQVGTITMDQCMWDVTERPDIQVGDVVELLGPHLASAGFSIQDWAD
QLGTISYELLCGLSARLPRVLVNVLGEAS

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=368, Percent_Identity=34.2391304347826, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1790487, Length=372, Percent_Identity=30.9139784946237, Blast_Score=138, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 46305; Mature: 46305

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHTPDDASALATAGHSPLATASASWTQSQGSQGADPVGETGFWPDFNPELELLTSRAWV
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEE
EIDAAQLRENLRLLQARLSPDTEIWAVVKANAYGHGARLVAPIALAAGAKGLCVATLAEG
EECHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
IELRQAGLQAPILVLGALNTWAELQQAMAARLEVSLTRAEQIPVMRQVARWAGRPVPVHV
HHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEE
NVDTGMTRLGIPWQEAAAVWGQICRIPELEGCSLFSHFATADEPDSPVMAQQEARFAQVV
ECCCCCEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHH
EQIRQAGDPLPPLHLDNSAGALIHLHYPRVRLGLALYGLSPAPHLQVPGLRPILRLKARL
HHHHHCCCCCCCEEECCCCCEEEEEECCHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
THIQTVPAHTGVSYGHRYVTSRPSRIATLAIGYADGIPRRLSGWLRGWVRGSLIQQVGTI
HHHEECCCCCCCHHCCHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCH
TMDQCMWDVTERPDIQVGDVVELLGPHLASAGFSIQDWADQLGTISYELLCGLSARLPRV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHCCHHHHHHH
LVNVLGEAS
HHHHHCCCC
>Mature Secondary Structure
MDHTPDDASALATAGHSPLATASASWTQSQGSQGADPVGETGFWPDFNPELELLTSRAWV
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEE
EIDAAQLRENLRLLQARLSPDTEIWAVVKANAYGHGARLVAPIALAAGAKGLCVATLAEG
EECHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
IELRQAGLQAPILVLGALNTWAELQQAMAARLEVSLTRAEQIPVMRQVARWAGRPVPVHV
HHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEE
NVDTGMTRLGIPWQEAAAVWGQICRIPELEGCSLFSHFATADEPDSPVMAQQEARFAQVV
ECCCCCEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHH
EQIRQAGDPLPPLHLDNSAGALIHLHYPRVRLGLALYGLSPAPHLQVPGLRPILRLKARL
HHHHHCCCCCCCEEECCCCCEEEEEECCHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
THIQTVPAHTGVSYGHRYVTSRPSRIATLAIGYADGIPRRLSGWLRGWVRGSLIQQVGTI
HHHEECCCCCCCHHCCHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCH
TMDQCMWDVTERPDIQVGDVVELLGPHLASAGFSIQDWADQLGTISYELLCGLSARLPRV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHCCHHHHHHH
LVNVLGEAS
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]