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The map label for this gene is era

Identifier: 86605904

GI number: 86605904

Start: 1231949

End: 1233025

Strand: Reverse

Name: era

Synonym: CYA_1220

Alternate gene names: 86605904

Gene position: 1233025-1231949 (Counterclockwise)

Preceding gene: 86605905

Following gene: 86605903

Centisome position: 42.04

GC content: 66.11

Gene sequence:

>1077_bases
ATGGAAGAAGAGCGACGGGAACGCGGCCATCCCCCTCTTCGGGATCCCGCTCCAGAGGAAGGGTGGCAGGAAGGGGCGGC
CCAAGCGCCGCCAGAGCTGGCCCCCCCCTACATCCCCCCGTACACGAGGGGACAAGAGGGTGGCCGGGGGGAGGCGGGGC
TGTCGGGGATCCCGGTCGCCCCACCGGGGTTTAAGTCGGGATTTGCGGCGCTCATCGGGCGGCCCAATGTGGGCAAGTCC
ACCTTGATGAACGCTCTGGTGGGCCAGAAGATCGCCATCACTTCTCCCGTGGCCCAGACCACCCGCAACCGCCTGCGGGG
GATCCTCTCTTTGCCGCAAGCCCAGATCATCTGGGTGGACACCCCTGGCATCCACAAGCCCCACCACCGCCTGGGGGAGA
TCTTGGTACACAACGCCCAGGCTGCCATTGGGAGCGTGGATGTCGTCCTCTTCGTGGTGGATGGCTCGGTGCCGGCAGGG
CGGGGGGATGCTTTTATCGCCGAGCGGATCCCCAGCGCGACCCCCTGCATCCTCGTCTGCAACAAAGCCGATCTGCTGCC
CAAAGAGTCTGCCGCGCGCCAGGCCCACCAAGAGAGCTACCAAGCCCTGCGCCCCGGTGCCCCCGTCGTCTGGGTGTCGG
CGTTGGATCCCGGCAGCTTGGCGCCCCTCATCCAGGCCACCGTCGACCTGCTGCCCCCTGGGCCCTACTACTATCCCCCG
GATCTGGTGACGGATCAGCCGGAGCGGTTTATCATGGCGGAGTTGATCCGCGAGCAAGTTCTCTTGCACACCCGCGAGGA
GGTGCCCCACTCGGTGGCCGTCACCATCGACCAGGTGGAAGAAACCCCCACCGTCACCCGCGTCCTGGCCACCCTCTACG
TGGAGCGGGACTCGCAAAAAGGGATCCTCATCGGCAAAGGGGGGGAAAGGCTCAAGCAAATTGGCCAGGCCGCCCGCCTC
CAGATTCAAAAGCTCATTGCCGGCAAGGTGTACCTGGAGCTGTTCGTCAAGGTGCGGCCCCACTGGCGGCGCTCCGAGCA
CCTGCTGCGCGACTTCGGCTACCGCGTTGAAACGTGA

Upstream 100 bases:

>100_bases
CCGAGCTGGGATCCCTCTCCCTGCAGTTGCCTGAGGTTTCCCTGGCCTTTGACAGTAGCCAGGCGCAGTCCTGGTCCGGC
TACCAGAGATAGGGGGCACG

Downstream 100 bases:

>100_bases
AGGGGTTTTGTGGCTGAGGTTGAGCTATCTGGTGGTATTGATGGGGATGCTGCACGTTGAGGTTAACGGCAATGCTGCGA
CTGTATGGGATCCCGACCTC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MEEERRERGHPPLRDPAPEEGWQEGAAQAPPELAPPYIPPYTRGQEGGRGEAGLSGIPVAPPGFKSGFAALIGRPNVGKS
TLMNALVGQKIAITSPVAQTTRNRLRGILSLPQAQIIWVDTPGIHKPHHRLGEILVHNAQAAIGSVDVVLFVVDGSVPAG
RGDAFIAERIPSATPCILVCNKADLLPKESAARQAHQESYQALRPGAPVVWVSALDPGSLAPLIQATVDLLPPGPYYYPP
DLVTDQPERFIMAELIREQVLLHTREEVPHSVAVTIDQVEETPTVTRVLATLYVERDSQKGILIGKGGERLKQIGQAARL
QIQKLIAGKVYLELFVKVRPHWRRSEHLLRDFGYRVET

Sequences:

>Translated_358_residues
MEEERRERGHPPLRDPAPEEGWQEGAAQAPPELAPPYIPPYTRGQEGGRGEAGLSGIPVAPPGFKSGFAALIGRPNVGKS
TLMNALVGQKIAITSPVAQTTRNRLRGILSLPQAQIIWVDTPGIHKPHHRLGEILVHNAQAAIGSVDVVLFVVDGSVPAG
RGDAFIAERIPSATPCILVCNKADLLPKESAARQAHQESYQALRPGAPVVWVSALDPGSLAPLIQATVDLLPPGPYYYPP
DLVTDQPERFIMAELIREQVLLHTREEVPHSVAVTIDQVEETPTVTRVLATLYVERDSQKGILIGKGGERLKQIGQAARL
QIQKLIAGKVYLELFVKVRPHWRRSEHLLRDFGYRVET
>Mature_358_residues
MEEERRERGHPPLRDPAPEEGWQEGAAQAPPELAPPYIPPYTRGQEGGRGEAGLSGIPVAPPGFKSGFAALIGRPNVGKS
TLMNALVGQKIAITSPVAQTTRNRLRGILSLPQAQIIWVDTPGIHKPHHRLGEILVHNAQAAIGSVDVVLFVVDGSVPAG
RGDAFIAERIPSATPCILVCNKADLLPKESAARQAHQESYQALRPGAPVVWVSALDPGSLAPLIQATVDLLPPGPYYYPP
DLVTDQPERFIMAELIREQVLLHTREEVPHSVAVTIDQVEETPTVTRVLATLYVERDSQKGILIGKGGERLKQIGQAARL
QIQKLIAGKVYLELFVKVRPHWRRSEHLLRDFGYRVET

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=318, Percent_Identity=29.2452830188679, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1788919, Length=294, Percent_Identity=36.734693877551, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI2367268, Length=128, Percent_Identity=37.5, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082120, Length=123, Percent_Identity=36.5853658536585, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 39091; Mature: 39091

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEERRERGHPPLRDPAPEEGWQEGAAQAPPELAPPYIPPYTRGQEGGRGEAGLSGIPVA
CCCHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPGFKSGFAALIGRPNVGKSTLMNALVGQKIAITSPVAQTTRNRLRGILSLPQAQIIWVD
CCCCHHHHHHHHCCCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCEEEEEEE
TPGIHKPHHRLGEILVHNAQAAIGSVDVVLFVVDGSVPAGRGDAFIAERIPSATPCILVC
CCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCHHHHHHCCCCCCEEEEE
NKADLLPKESAARQAHQESYQALRPGAPVVWVSALDPGSLAPLIQATVDLLPPGPYYYPP
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCC
DLVTDQPERFIMAELIREQVLLHTREEVPHSVAVTIDQVEETPTVTRVLATLYVERDSQK
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCHHHHHHHHHHHHCCCCCC
GILIGKGGERLKQIGQAARLQIQKLIAGKVYLELFVKVRPHWRRSEHLLRDFGYRVET
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEEERRERGHPPLRDPAPEEGWQEGAAQAPPELAPPYIPPYTRGQEGGRGEAGLSGIPVA
CCCHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPGFKSGFAALIGRPNVGKSTLMNALVGQKIAITSPVAQTTRNRLRGILSLPQAQIIWVD
CCCCHHHHHHHHCCCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCEEEEEEE
TPGIHKPHHRLGEILVHNAQAAIGSVDVVLFVVDGSVPAGRGDAFIAERIPSATPCILVC
CCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCHHHHHHCCCCCCEEEEE
NKADLLPKESAARQAHQESYQALRPGAPVVWVSALDPGSLAPLIQATVDLLPPGPYYYPP
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCC
DLVTDQPERFIMAELIREQVLLHTREEVPHSVAVTIDQVEETPTVTRVLATLYVERDSQK
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCHHHHHHHHHHHHCCCCCC
GILIGKGGERLKQIGQAARLQIQKLIAGKVYLELFVKVRPHWRRSEHLLRDFGYRVET
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]